CHEMOPREVENTION OF COLON AND MAMMARY CANCER BY THE KOREAN FOOD STUFFS

  • Kim, Dae-Joong (Structural BioInformatics & Cancer Prevention, College of Veterinary Medicine & Research Institute of Veterinary Medicine, Chungbuk National University) ;
  • Byeongwoo Ahn (Department of Pathology, National Institute of Toxicology Research, Korea Food and Drug Administratio) ;
  • Kang, Jin-Seok (Department of Pathology, National Institute of Toxicology Research, Korea Food and Drug Administratio) ;
  • Nam, Ki-Taek (Department of Pathology, National Institute of Toxicology Research, Korea Food and Drug Administratio) ;
  • Park, Mina (Department of Pathology, National Institute of Toxicology Research, Korea Food and Drug Administratio) ;
  • Shin, Dong-Hwan (Department of Pathology, National Institute of Toxicology Research, Korea Food and Drug Administratio) ;
  • Jang, Dong-Deuk (Department of Pathology, National Institute of Toxicology Research, Korea Food and Drug Administration)
  • Published : 2001.10.01

Abstract

In the present study, we examined the chemopreventive effects of indole-3-carbinol (I3C), a constituent of cruciferous vegetables (the Family of Cruciferae) such as cabbages, cauliflowers and broccoli on multiple intestinal neoplasia (Min) genetic mouse model and on mouse colon carcinogenesis induced by azoxymethane (AOM) as well as on rat mammary carcinogenesis induced by 7, 12-dimethybenz[$\alpha$]anthracene (DMBA).(omitted)

Keywords