MECHANISMS AND APPLICATIONS OF NSAIDS IN THE CHEMOPREVENTION OF CANCER

  • Steele, Vernon E. (Division of Cancer Prevention National Cancer Institute, NIH)
  • Published : 2001.10.01

Abstract

Significant evidence exists which demonstrates that inflammation predisposes and promotes the cancer process in humans. Chronic inflammation can induce cancer in a variety of organ sites, including bowel and lung. There is also firm evidence that induced cyclooxygenases and nitric oxide synthetases, prostaglandins, and inflammatory cytokines can promote and accelerate the carcinogenic process.(omitted)

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