Proceedings of the KSAR Conference (한국동물번식학회:학술대회논문집)
- 2001.03a
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- Pages.19-19
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- 2001
Cloning and Characterization of Porcine Uroplakin II Gene
- D. N. Kwon (Dept. of Dairy Science, Division of Applied Life Science, Gyeongsang National University) ;
- H. K. Shin (Dept. of Dairy Science, Division of Applied Life Science, Gyeongsang National University) ;
- C. K. Hwang (Dept. of Dairy Science, Division of Applied Life Science, Gyeongsang National University) ;
- D. W. Ok (Dept. of Dairy Science, Division of Applied Life Science, Gyeongsang National University) ;
- Kim, J. H. (Dept. of Dairy Science, Division of Applied Life Science, Gyeongsang National University)
- Published : 2001.03.01
Abstract
Mammalian urothelium undergoes unique membrane specialization by making the asymmetric unit membrane (AUM) that is covered with the apical cell surface during terminal differentiation. The AUM contains several major integral membrane proteins including uroplakin Ia, Ib, II and III. The genes for uroplakins have been cloned from humans and mice, but not from porcine. In this study, we report the cloning of the UPII genomic DNA, which codes for the full length open reading frame for the uroplakin II protein. The deduced amino acid sequence encodes of a hydrophobic NH