한국생물공학회:학술대회논문집
- 한국생물공학회 2000년도 추계학술발표대회 및 bio-venture fair
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- Pages.713-714
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- 2000
Human Cardiac Troponin I 면역분석을 위한 단일클론 항체의 특성화
초록
Six monoclonal antibodies to human cardiac troponin I (hcTnI) were produced to eventually develop an immunosensor for acute myocardial infarction (AMI). For the characterization of these antibodies, a set of 11 different peptides covering selected ranges of the complete amino acid sequence of hcTnI was prepared and used for epitope mapping. Such analysis allowed to select an appropriate pair of antibodies that can form a sandwich type of immune complexes and was consequently used for an immunoassay.
키워드