한국생물공학회:학술대회논문집
- 2000.04a
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- Pages.592-595
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- 2000
PCR-based genotyping of Korean population for forensic applications
- Published : 2000.04.08
Abstract
In human chromosome, a short sequence of DNA has been repeated a number of times. These repeats are called variable number of tandem repeat(VNTR) or short tandem repeat(STR) which has short repeat core. VNTR and STR are used in the field of forensic science, evolution, and anthropology. In this work, we examined allele frequencies of 3 VNTR(YNZ22, NeuR, D21S11) and one STR(Humth01) in a Korean population sample by polymerase chain reaction(PCR) followed by high-resolution polyacrylamide gelelectrophoresis(PAGE) with silver staining. Subsequently, the polymorphism information content(PIC) was calculated : the highest PIC was observed for the NeuR locus(0.95680) and lowest for the Humth01 locus(0.75809).
Keywords
- Variable Number of Tandem Repeat(VNTR);
- Short Tandem Repeat(STR);
- Polymorphism Information Content(PIC);
- Polymerase Chain Reaction(PCR)