Proceedings of the KOSOMBE Conference (대한의용생체공학회:학술대회논문집)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Bone Ingrowth and Enhancement of Bone Bonding Strength at Interface between Bone and HA Coated Stainless Steel

HA 코팅된 스테인레스강과 뼈의 계면에서의 경조직 성장 및 결합력 향상

  • Kim, C.S. (Department of Biomedical Engineering, College of Medicine, Konkuk University) ;
  • Kim, S.Y. (Department of Orthopedic Surgery, College of Medicine, Konkuk University) ;
  • Kim, D.H. (Department of Pathology, College of Medicine, Konkuk University) ;
  • Khang, G. (Department of Biomedical Engineering, College of Medicine, Konkuk University)
  • 김철생 (건국대학교 의과대학 의학공학과) ;
  • 김상윤 (건국대학교 의과대학 병리학교실) ;
  • 김동헌 (건국대학교 의과대학 정형외과학교실) ;
  • 강곤 (건국대학교 의과대학 의학공학과)
  • Published : 1996.05.17
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Abstract

We investigated how hydroxyapatite (HA) coating onto a porous super stainless steel (S.S.S, 22Cr-20Ni-6Mo-0.25N) affects bone ingrowth in a dog transcortical femoral model. Implants were histologically evaluated after 4 and 48 weeks of implantation, and the bone bonding strength at the bone/implant interface was examined by employing the pull-out test. The direct osseous tissue bonding onto the HA-coated S.S.S was observed, but the uncoated stainless steels had thin fibrous tissue layers. The mean interface strength of the HA-coated S.S.S was 1.5 and 2.5 times greater than those of the S.S.S and the 316L SS after one year of implantation, respectively. In preliminary studies, no toxic responce was observed from a cytotoxicity test of the S.S.S, having similar corrosion resistance to titanium. Our results suggest that early osteoconductive nature of HA coating may induce long term osteointegration for a bioinert substrate.

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