한국생물물리학회:학술대회논문집 (Proceedings of the Korean Biophysical Society Conference)

한국생물물리학회 (The Korean Biophysical Society)
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CONTRIBUTION OF DIFFERENT TYPES OF $Ca^{2+}$ CHANNELS TO CATECHOLAMINE SECRETION IN RAT CHROMAFFIN CELLS

  • Goo, Yong-Sook (College of Medicine, Chungbuk National University) ;
  • Jina Roh (College of Medicine, Chungbuk National University) ;
  • Lee, Jung-Hwa (College of Medicine, Chungbuk National University) ;
  • Cha, Eun-Jong (Department of Physiology ＆ Biomedical Engineering)
  • 발행 : 1996.07.01
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초록

Adrenal chromaffin cells secrete catecholamine in response to acetylcholine. The secretory response has absolute requirement for extracellular calcium, indicating that $Ca^{2+}$ influx through voltage operated $Ca^{2+}$ channels (VOCC) is the primary trigger of the secretion cascade. Although the existence of various types of $Ca^{2+}$ channels has been explore using patch clamp techique in adrenal chromaffin cells, the contribution of different types of $Ca^{2+}$ channels to catecholamine secretion remains to be establised. (omitted)omitted)

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