Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)

The Korean Biophysical Society (한국생물물리학회)
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Conformation of Luteinizing Hormone Releasing Hormone as Studied by $^1$H NMR

  • Yi, Gwan-Su (Department of Biological Sciences Korea Advanced Institute of Science and Technology, Magnetic Resonance Group, Korea Basic Science Institute) ;
  • Chaejoon Cheon (Magnetic Resonance Group, Korea Basic Science Institut) ;
  • Park, Byong-Seok (Department of Chemistry, Korea Advanced Institute of Science and Technolog) ;
  • Kim, Hyoungman (Department of Biological Sciences Korea Advanced Institute of Science and Technology)
  • Published : 1996.07.01
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Abstract

NMR studies on the structure of the luteinizing hormone releasing hormone (LHRH) in aqueous buffer and trifluoroethanol (TFE)/aqueous buffer (1:1, v/v) solution were performed. The NMR data under these conditions suggested a unique conformation which includes a ${\beta}$-1 turn of the Tyr5-Arg8 segment and an unusual turn of Ser4-Gly6 segment staggered with the ${\beta}$-I turn. (omitted)

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