대한의용생체공학회:학술대회논문집 (Proceedings of the KOSOMBE Conference)

대한의용생체공학회 (The Korean Society of Medical and Biological Engineering)
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알진이 도포된 인공혈관의 물성 평가

In vitro investigation of algin impregnated vascular graft

  • 이진오 (한국화학연구소 고분자제3연구실) ;
  • 신병철 (한국화학연구소 고분자제3연구실) ;
  • 강길선 (한국화학연구소 고분자제3연구실) ;
  • 이해방 (한국화학연구소 고분자제3연구실)
  • Lee, Jin-Ho (Polymer Research Lab.3, Korea Research Institute of Chemical Technology) ;
  • Shin, Bung-Chul (Polymer Research Lab.3, Korea Research Institute of Chemical Technology) ;
  • Khang, Gil-Son (Polymer Research Lab.3, Korea Research Institute of Chemical Technology) ;
  • Lee, Hai-Bang (Polymer Research Lab.3, Korea Research Institute of Chemical Technology)
  • 발행 : 1990.05.23
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초록

He impregnated a highly porous, knitted polyester (Dacron) graft with a biodegradable nonproteinaceous material, algin. This new vascular graft is blood tight but still retains high porosity in the body. It does not need to be preclotted with blood before implantation and has good tissue ingrowth and biological healing properties due to the high porosity. The algin impregnated graft was investigated by "in vitro" examinations in this study. It was characterized by ESCA analysis, SEM observation, and measurements of water permeability, algin coating weight, mechanical properties and whole blood clotting time. The water permeability of the graft was reduced more than 99% by the algin impregnation treatment without changing any mechanical properties. "In vivo" examinations of the algin impregnated vascular graft are on progress.

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