• Title/Summary/Keyword: zoonotic

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Characteristics of Salmonella spp isolated from poultry carcasses (닭 도체에서 분리한 Salmonella spp의 특성 분석)

  • Lee, Ho-Won;Hong, Chong-Hae;Jung, Byeong-Yeal
    • Korean Journal of Veterinary Service
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    • v.30 no.3
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    • pp.339-351
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    • 2007
  • Salmonella infections cause the diseases in poultry and some zoonotic Salmonella can be transmitted to human through poultry products, resulting in food-borne disease. This study was conducted to obtain some useful information for the control of salmonellosis in human. Twenty four Salmonella spp were isolated from poultry carcasses, and they were examined with several methods such as serotyping, antimicrobial resistance test and random amplified polymorphic DNA(RAPD) to identify their characteristics. In serotyping test of 24 strains S enteritidis was 17 (70.8%), followed by S schwarzengrund 3 (12.5%), untyped strain 4 (16.7%). In the results of antimicrobial resistance test, 23 (95.8%) isolates were resistant to at least one antimicrobial agent, generating eight different resistance patterns. In RAPD analysis using URP-6 primer to differentiate Salmonella isolates within a serotype, 4 serogroups were divided into 10 RAPD types: 5 types in S enteritidis, 2 types in S schwarzengrund and 3 types in the remainder.

Isolation of Photobacterium damselae subsp. damselae from zebra shark Stegostoma fasciatum

  • Han, Jee Eun;Gomez, Dennis K.;Kim, Ji Hyung;Choresca, Casiano H. Jr.;Shin, Sang Phil;Baeck, Gun Wook;Park, Se Chang
    • Korean Journal of Veterinary Research
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    • v.49 no.1
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    • pp.35-38
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    • 2009
  • The zebra shark Stegostoma fasciatum which had been reared in the commercial aquaria was found dead and submitted for postmortem examination. A pure bacterial culture was isolated from pale and enlarged liver. The analysis of ureC and 16S rRNA genes confirmed the isolate as Photobacterium (P.) damselae subsp. damselae and this pathogen was sensitive to gentamicin. Although, no mortality in mouse was observed in the experimental infection study, the isolation of this pathogen in aquarium fish is significant because it can act as a reservoir to other aquatic animals and can also be zoonotic potential to human during aquarium management. This paper describes the first isolation of P. damselae subsp. damselae from zebra shark.

Helminths in Rattus norvegicus captured in Chunchon, Korea (춘천에서 잡은 시궁쥐(Rattus norvegicus)의 윤충 감염)

  • SEONG, Je-Kyung;HUH, Sun;Lee, Joon-Sup;OH, Yang-Seok
    • Parasites, Hosts and Diseases
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    • v.33 no.3
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    • pp.235-238
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    • 1995
  • We report helminthic infections in the liver and intestine of Rattus norvegicus captured in Chunchon, Korea from April to October 1994. Out of 43 examined rats, eggs of Capillaria hepatica were found in 11, Hymenolepis diminuta in 14 and Taenia taeniaeformis metacestodes in 28. Those rats can be cources of zoonotic infections in the curveyed area.

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Current Knowledge of Small Flukes (Digenea: Heterophyidae) from South America

  • Santos, Claudia Portes;Borges, Juliana Novo
    • Parasites, Hosts and Diseases
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    • v.58 no.4
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    • pp.373-386
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    • 2020
  • Fish-borne heterophyid trematodes are known to have a zoonotic potential, since at least 30 species are able to infect humans worldwide, with a global infection of around 7 million people. In this paper, a 'state-of-the-art' review of the South American heterophyid species is provided, including classical and molecular taxonomy, parasite ecology, host-parasite interaction studies and a list of species and their hosts. There is still a lack of information on human infections in South America with undetected or unreported infections probably due to the information shortage and little attention by physicians to these small intestinal flukes. Molecular tools for specific diagnoses of South American heterophyid species are still to be defined. Additional new sequences of Pygidiopsis macrostomum, Ascocotyle pindoramensis and Ascocotyle longa from Brazil are also provided.

Molecular detection of bat coronaviruses in three bat species in Indonesia

  • Dharmayanti, Ni Luh Putu Indi;Nurjanah, Diana;Nuradji, Harimurti;Maryanto, Ibnu;Exploitasia, Indra;Indriani, Risa
    • Journal of Veterinary Science
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    • v.22 no.6
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    • pp.70.1-70.12
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    • 2021
  • Bats are an important reservoir of several zoonotic diseases. However, the circulation of bat coronaviruses (BatCoV) in live animal markets in Indonesia has not been reported. Genetic characterization of BatCoV was performed by sequencing partial RdRp genes. Real-time polymerase chain reaction based on nucleocapsid protein (N) gene and Enzyme-linked immunosorbent assay against the N protein were conducted to detect the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral RNA and antibody, respectively. We identified the presence of BatCoV on Cynopterus brachyotis, Macroglossus minimus, and Rousettus amplexicaudatus. The results showed that the BatCoV included in this study are from an unclassified coronavirus group. Notably, SARS-CoV-2 viral RNA and antibodies were not detected in the sampled bats.

A New ELISA Kit Based on Antigenic Epitopes for Diagnosing Brucella abortus

  • Khodabakhsh, Tannaz;Arabi, Azin;Pakzad, Parviz;Gheflat, ShivaSadat;Bahreinipour, Akram;Bandehpour, Mojgan
    • Microbiology and Biotechnology Letters
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    • v.47 no.1
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    • pp.158-163
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    • 2019
  • Brucellosis is one of the most important zoonotic diseases that lead to a great amount of economic losses. Prevention and diagnosis are both necessary to eradicate this disease. The identification and evaluation of different antigens of Brucella spp. play a key role in the progress of diagnostic programs. In this study, we designed, produced, and evaluated a 24-kDa polypeptide containing antigenic epitopes of VirB2, 3, and 9 of Brucella abortus for use with the ELISA kit. The produced polypeptide is appropriate for diagnosing brucellosis in bovines by a laboratory diagnostic kit, with 100% sensitivity and 97.5% specificity.

COVID-19 Drug Development

  • Kim, Seungtaek
    • Journal of Microbiology and Biotechnology
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    • v.32 no.1
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    • pp.1-5
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    • 2022
  • Diagnostics, vaccines, and drugs are indispensable tools and control measures employed to overcome infectious diseases such as coronavirus disease 2019 (COVID-19). Diagnostic tools based on RT-PCR were developed early in the COVID-19 pandemic and were urgently required for quarantine (testing, tracing and isolation). Vaccines such as mRNA vaccines and virus-vectored vaccines were also successfully developed using new platform technologies within one year after identifying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as the causative agent of COVID-19. Drug development has been conducted in various ways including drug repurposing, convalescent plasma therapy, and monoclonal antibody development. Among the above efforts, this review examines COVID-19 drug development along with the related and upcoming challenges.

Complete genome sequence of a methicillin-resistant Staphylococcus schleiferi strain from canine otitis externa in Korea

  • Lee, Gi Yong;Yang, Soo-Jin
    • Journal of Veterinary Science
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    • v.21 no.1
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    • pp.11.1-11.7
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    • 2020
  • The increase in canine skin and soft tissue infections, such as pyoderma and otitis, caused by Staphylococcus schleiferi strains, is of significant zoonotic concern. In this study, we report the first complete genome sequence for a methicillin-resistant clinical isolate of S. schleiferi (MRSS) designated as SS4, obtained from a dog with otitis externa, in Korea. The genome of SS4 strain was of 2,539,409 bp and presented high G+C content ratio (35.90%) with no plasmid. Comparative analysis of SS4 genome revealed that it is closely related to 2142-05 and 5909-02 strains isolated from the canine skin infections in the USA.

Eight cases of canine thelaziosis found in two localities in Korea

  • Seongjun Choe;Sunmin Kim;Tilak Chandra Nath;Jeong-Ho Kim
    • Parasites, Hosts and Diseases
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    • v.61 no.3
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    • pp.325-331
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    • 2023
  • Thelazia callipaeda, a parasitic nematode that causes thelaziosis in various mammals, including humans, is known to be endemic in Korea. However, life cycle-related information on the parasite, primarily from human infection and a few dog cases, is limited. This study reports additional cases of T. callipaeda infections in dogs from both rural and urban areas in Korea, indicating the potential for transmission to humans and other animals. We collected 61 worms from 8 infected dogs from Paju and Cheongju Cities and observed their morphological characteristics under a light microscope. The findings indicate that T. callipaeda infections in animals in Korea may be underestimated and are distributed close to human environments. Our results contribute to the growing knowledge of the reservoir hosts of T. callipaeda in Korea and highlight the importance of continued surveillance and research to prevent and control this emerging zoonotic disease.

Streptococcus suis causes bacterial meningitis with hearing loss in patients without direct exposure to pigs in a regional pork industry territory

  • Joong-Goo Kim;Gil Myeong Seong;Young Ree Kim;Sang Taek Heo;Jeong Rae Yoo
    • Journal of Medicine and Life Science
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    • v.20 no.1
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    • pp.43-47
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    • 2023
  • Streptococcus suis (S. suis) is an emerging zoonotic pathogen that causes bacterial meningitis in humans. S. suis is an encapsulated gram-positive facultative anaerobic bacterium and is an important pathogen in pigs. This infectious disease usually manifests in humans as meningitis, endocarditis, septicemia, and arthritis. Most cases originate in Southeast Asia, and human S. suis infections are often reported in countries with a high density of pigs. Meningitis is a common clinical manifestation of S. suis infection. Moreover, hearing loss is a common complication that can be bilateral, profound, and/or permanent. This report presents two cases of bacterial meningitis and hearing loss caused by S. suis in patients without a history of direct exposure to pigs in an intensive pork industry region.