• Nutrition Research and Practice
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• v.17 no.5
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• pp.883-898
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• 2023

BACKGROUND/OBJECTIVES: Probiotics have been suggested as potent modulators of age-related disorders in immunological functions, yet little is known about sex-dependent effects of probiotic supplements. Therefore, we aimed to investigate sex-dependent effects of probiotics on profiles of the gut microbiota and peripheral immune cells in healthy older adults. SUBJECTS/METHODS: In a randomized, double-blind, placebo-controlled, multicenter trial, healthy elderly individuals ≥ 65 yrs old were administered probiotic capsules (or placebo) for 12 wk. Gut microbiota was analyzed using 16S rRNA gene sequencing and bioinformatic analyses. Peripheral immune cells were profiled using flow cytometry for lymphocytes (natural killer, B, CD4⁺ T, and CD8⁺ T cells), dendritic cells, monocytes, and their subpopulations. RESULTS: Compared with placebo, phylum Firmicutes was significantly reduced in the probiotic group in women, but not in men. At the genus level, sex-specific responses included reductions in the relative abundances of pro-inflammatory gut microbes, including Catabacter and unclassified_Coriobacteriales, and Burkholderia and unclassified Enterobacteriaceae, in men and women, respectively. Peripheral immune cell profiling analysis revealed that in men, probiotics significantly reduced the proportions of dendritic cells and CD14⁺ CD16^- monocytes; however, these effects were not observed in women. In contrast, the proportion of total CD4⁺ T cells was significantly reduced in women in the probiotic group. Additionally, serum lipopolysaccharide-binding protein levels showed a decreasing tendency that were positively associated with changes in gut bacteria, including Catabacter (ρ = 0.678, P < 0.05) and Burkholderia (ρ = 0.673, P < 0.05) in men and women, respectively. CONCLUSIONS: These results suggest that probiotic supplementation may reduce the incidence of inflammation-related diseases by regulating the profiles of the gut microbiota and peripheral immune cells in healthy elders in a sex-specific manner.

• Biomedical Science Letters
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• v.10 no.4
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• pp.467-472
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• 2004

Transcranial Doppler sonography (TCD) is a useful diagnostic method to measure cerebral blood flow velocity in various cerebral disorders. However, we haven't data enough to be available for young persons, especially in the twenties in Korea. This study was performed to collect the basic data of the cerebral blood flow velocity and to understand the cerebral physiology in the twenties. We determined the mean velocities of middle, anterior, and posterior cerebral artery, and vertebral and basilar artery (MCA-V, ACA-V, PCA-V, VA-V, and BA-V, respectively) in eighty-two healthy volunteers. For evaluating cerebral autoregulation, only the MCA- V was measured under various conditions such as stable, apnea, and hyperventilation state. Right and left MCA-V were 80.66±14.03 and 83.22±14.40 cm/sec at stable state, 90.13±17.47 and 90.26±16.38 cm/sec at apnea, and 54.83±11.09 and 55.33±10.74 cm/sec at hyperventilation. Right and left ACA-V were 49.11±15.71 and 48.19±13.75 cm/sec. Right and left PCA-V were 39.44±9.12 and 37.91±6.74 cm/sec. Right and left VA-V were 33.65±9.26 and 36.l8±10.39 cm/sec. BA-V was 48.49±11.16 cm/sec. Right and left MCA- V, V A-V, and right ACA- V and PCA- V in women were higher than those of men (P<0.05). No significant differences were found between men and women in the others. These findings indicate that cerebral hemodynamics and autoregulation were normal in young people in their twenties. The velocities of MCA, ACA, PCA, and BA were high values in women as compared with men.

• Archives of Obesity and Metabolism
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• v.3 no.1
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• pp.1-8
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• 2024

Background: This study investigated the association between obesity and cardiometabolic disease clusters in Korean adults aged 19-39 years. Methods: We included 3,785 participants (1,767 men and 2,018 women) aged 19-39 years who participated in the Korea National Health and Nutrition Examination Survey (2020-2022). The risk factors for cardiometabolic disease were defined as follows: high blood pressure; hypertriglyceridemia; hyperuricemia; and high low-density lipoprotein cholesterol, low high-density lipoprotein cholesterol, high fasting plasma glucose, elevated alanine aminotransferase levels. Results: The prevalence of participants with ≥ 1, ≥ 2, and ≥ 3 cardiometabolic disease risk factors was 95.2%, 84.2%, and 65.6% in men and 90.0%, 70.5%, and 43.0%, in women with class 2-3 obesity, respectively. Compared to those for young adults with underweight/normal weight, the odds ratios (ORs) and 95% confidence intervals (CIs) for the clustering of cardiometabolic risk factors were 17.26 (8.32-35.80) for ≥ 1; 19.43 (12.18-31.00) for ≥ 2; and 22.93 (14.15-37.15) for ≥ 3 factors in men with class 2-3 obesity and 14.67 (8.00-26.91) for ≥ 1; 20.88 (12.15-35.88) for ≥ 2; and 36.26 (20.20-65.09) for ≥ 3 factors in women with class 2-3 obesity. Conclusion: Although the patients were young, the prevalence and ORs for cardiometabolic disease risk factor clusters in young adults with obesity were prominently high. Prevention and management of obesity in young Korean adults are urgently needed at both individual and public levels.

• Journal of Family Resource Management and Policy Review
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• v.16 no.4
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• pp.195-211
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• 2012

The purpose of this study is to investigate the relationship between leisure time and time pressure based on time availability perspective and gender perspective. For this purpose, this study examined the use of leisure time and the level of time pressure according to gender and gender role attitudes and investigated the relationship between leisure time and time pressure focusing on gender differences in the moderating effect of gender role attitudes. The sample for the study was drawn from the Time Use Survey data collected by Korean National Statistical Office in 2009. Two cases were gathered from each of the samples who are married, aged over 20, presently working and raising preschoolers, which makes 3,150 cases in the total. The major findings are as follows. First, the differences of leisure time between groups according to gender role attitude are not significant, but gender differences are significant. Men's leisure time is more than women's leisure time. Secondly, people with progressive gender role attitudes have higher time pressure than people with conservative gender role attitudes. By the gender groups, women's time pressure is higher than men's time pressure. Thirdly, men's time pressure is decreasing as leisure time increases, but effect of leisure time on women's time pressure is not significant. Women with progressive gender role attitudes have higher time pressure than women with conservative gender role attitudes. On the other hand, influence of gender role attitudes on men's time pressure is not significant. Fourthly, only male group has a significant moderating effect of gender role attitudes in the relationship between leisure time and time pressure. In other words, time pressure of men with conservative gender role attitudes is decreasing more sharply than men with progressive gender role attitudes as leisure time increases. In contrast, increased leisure time does not relieve women's time pressure even though they have conservative gender role attitudes. These results show that men's time pressure can be interpreted in the time availability perspective, while women's time pressure can be described in gender perspective.

• Journal of Preventive Medicine and Public Health
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• v.31 no.3 s.62
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• pp.395-403
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• 1998

To estimate the incidence rate of coronary heart disease in Korea, of all residents in Taegu city aged 25 or above, those who had an acute MI or a fatal coronary event between 1 July 1996 and 30 June 1997 were registered. Seven hundreds and eight patients were registered during the study period(685 were identified at hospital and 23 were autopsy cases). Age-standardized annual incidence rate of men in city area was 93 per 100,000(95% CI; 61-142) and 35% CI; 16-67) in women(100 in men and 20 in women aged 35-64). The incidence was rapidly increased after age 40 in men, however, in women after age 60. Twenty-eight-days case fatality rate was 45% in men and 47% in women. However, in the age group of 45-59 case fatality rate in women was two times higher than that in men. In conclusion, crude annual incidence rate of CHD in city area was 73 per 100,000 in men and 33 in women. The age-standardized annual incidence of CHD in men(93 per 100,000) was 2 times higher than that in women (33 per 100,000) in Korea.

• Journal of Korean Medicine for Obesity Research
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• v.10 no.1
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• pp.41-48
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• 2010

Background The length of the second digit (the index finger) relative to the length of the fourth digit (the ring finger) is sexually dimorphic as males have a lower second to fourth digit ratio (2D:4D). There is evidence that sex differences in 2D:4D arise from in utero concentrations of sex steroids, with a low 2D:4D (male typical ratio) being positively related to prenatal testosterone, while a high 2D:4D (female typical ratio) is positively associated with prenatal oestrogen Objective To investigate possible associations between 2D:4D ratio and sexually dimorphic body composition Methods 2D:4D ratio, body mass index (BMI), waist circumference, waist-hip ratio (WHR), weight, and body fat percentage was measured from 46 men and 20 women Results Digit ratio was found to be significantly lower in men than in women. No significant correlation between 2D:4D ratio and body compositions was found for both men and women while digit ratio in obese men was significantly higher than normal weight men. Conclusion This finding dose not support the significant correlation between digit ratio and sexually dimorphic body composition. However digit ratio in obese men was significantly higher than normal weight men.

• Journal of the Korea Safety Management & Science
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• v.23 no.4
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• pp.49-53
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• 2021

The objective of this study was to understand which type of fire hose should be placed in indoor fireplug box upon analyzing the preparation time between rack-type fire hose and reel-type one. With respect to the type of hose, rack-type stacking method was used and hose preparation time was measured with 5 times of repeat test, separating men and women. Study results reveal that preparation time of reel-type fire hose took longer than that of rack-type one in both men and women. For both rack-type hose and reel-type hose, preparation time by two persons took shorter than that by one man. Also, preparation time by three persons took shorted than that by two women. Preparation time for both rack-type hose and reel-type one by men took shorter than that by women. In summary, it was confirmed that rack-type hose could be prepared within shorter time than reel-type one. Since the size of drum set in the reel-type fire hose is relatively small, it had some difficulty in preparation of fire hose timely.

• Korean Institute of Interior Design Journal
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• v.22 no.1
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• pp.3-10
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• 2013

This study, with a space of cafeteria for the object, selected adjective and space for space evaluation based on existing dissertations and experts' survey so as to analyze the perception features by adjective into perception types. At space evaluation, the purpose of visiting the cafeteria was setup for test. Analysis of what perceptual information on the space was acquired enables to set up any features at a space and the direction of designing. The approach through the evaluation of space perception assigning this kind of observing intentionality can be applied to emotion technique which connects a designer to customers. From this study, the following conclusion has been reached. Frist, the difference at perception type by gender is formality, which is higher with women than men. When it is considered that other types are identical, it can be seen that the formality is the perception type to decide the selection of gender and has the highest average value among all the three types. On the whole, men have the tendency for regarding spaciality as the most important, while women have that for looking upon formality as such. Second, to the question what element they would see first when visiting for conversation, men and women answered respectively that they would see partition (35.6%) and chairs (38.0%). Men had a very strong propensity for the element of area section(partition) supporting the activity of purpose and women regarded the element of behavior support(chair) carrying out the activity of purpose as important. Third, the analysis of deviance shown at the formality of perception type showed that men had dispersive selection at the process of selecting all adjectives and their features at the process of space perception were higher than spaciality and fancine.

• Journal of Distribution Science
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• v.14 no.2
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• pp.33-39
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• 2016

Purpose The purpose of this study is to investigate the impact of gender differences in DNA on consumer buying behavior both online and offline and other buying channels to find out effective sales promotion strategies of enterprises. Research design, data, and methodology - This study investigated the relation between chromosome and DNA, DNA and gene, and gene and human behavior of gender. The study shows generic characteristics have influence upon consumers' buying behavior and inclination, and examined the effects of genetic characteristics depending upon the difference of gender DNA upon consumers' buying behavior. Results - Precedent studies on genetics and ethology showed close relations between chromosome and DNA, DNA and gene, and gene and buying behavior of the gene. 'Hunting and protection', one of the genetic characteristics in men's DNA, had great influence upon the consumers' different buying behavior. Conclusion - Gender DNA difference in genetics and ethology disclosed fundamental reasons for the difference in buying behavior and inclination of men and women. It gives implications that marketing strategies of advertising and sales promotion should be made in different ways depending upon men and women.

• Journal of Families and Better Life
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• v.24 no.1 s.79
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• pp.129-140
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• 2006

The purpose of this study was to understand the labor division between men's housework and market work and to research the change of men's contribution to housework. And it was also examined what kinds of valuables work on a change in men's market work and housework. The information about men's change in the labor division was collected from the biggest 5 news papers in Korea for last five years for this study. And either men's new participation trend to household work did. Words searched for this study were men, labor, family, home, housewife, work, household work, father etc. Korean men have experienced a overloaded breadwinner role and have worked most in the world since 1960s. But Korean men's working time was continuously decreased a little every year. As Korean Companies had fired many worker during IMP economic crisis period, Korean men had to work more than before because of decreased fellows and they should have concentrated on their work at the sacrifice of private life and family-sharing time. On the other hand, some men were started to participate to do housework as a results of long-unemployment and early retirement after this periods. 5 day working system be in forced gradually since 2003 especially make men come back home and interest on housework. So Korean men's housework participation is gradually increasing by the practical application of sex-equitable politics such as 5 day working system and men's suspension regime for baby care. father's increased participation to children education and care, men's new family-oriented life style, dual-sexuality education system, and socially changed perception to husband housemaker. These interrelated trends demands us to shape a new labor division pattern in the family that make change the breadwinner/homemaker conception by the gender role. Now, all of family, men, women, and children have to join housework. It would help women, men, and all families make more human and equitable relationship.