• Title/Summary/Keyword: wisdom of science

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The Trend of e-Science Projects for Virtual Screening (Virtual Screening을 위한 e-Science 프로젝트 동향)

  • KIM, Nam Gyu;AHN, Sun Il;LEE, Sehoon;LEE, June H.;HWANG, Soon Wook
    • Proceedings of the Korea Contents Association Conference
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    • 2007.11a
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    • pp.569-573
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    • 2007
  • e-Science is a new paradigm to increase the research efficiency by applying the state-of-the-art information technology to the classical research methodology. Among the research fields influenced by e-Science, Biology and Bioinformatics are the fields that are using IT very actively. And virtual screening, a procedure for the drug discovery, is one of the bioinformatics applications which requires a large amount of computing resources. In this paper, WISDOM, which is a e-Science project to design a new drug for Malaria and Avian flu, and related projects are introduced and the joint research between KISTI and Chun-nam university planned for the virtual screening research is explained.

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Different mechanism of visual attention in anxious and non-anxious population (부정자극 지각에 관련된 불안인과 정상인의 공간주의 비교연구)

  • Choi, Moon-Gee;Koo, Min-Mo;Park, Kun-Woo;Nam, Ki-Chun
    • Korean Journal of Cognitive Science
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    • v.20 no.1
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    • pp.51-77
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    • 2009
  • Using a modified Posner's cue-target paradigm, we investigated whether negative cues attract more attention than neutral cues in anxious people. Previous studies used commonly an unbalanced proportion of valid and invalid trials(75% vs. 25% respectively). But in the present study, an equivalent proportion of valid and invalids trials was used for measuring detection speed of cues without participant's expectancy caused by the unbalanced proportion. Emotional words(Experiment 1) and facial expressions(Experiment 2) were used as cues for target locations. The result of Experiment 1 and 2 showed that threatening cues facilitated target detection in valid trials and interfered with it in invalid trials in anxious participants and a, reverse response patterns were found in non-anxious participants. This indicates that threatening cues attract more attention to the cued location in anxious people and in contrast, non-anxious people avoid threatening stimuli. In Experiment 3, we investigated the difference of validity effect across anxiety levels. The results showed that anxious participants gave less attention to cued location when the cues were non-informative whereas non-anxious participants gave more attention to cued locations in the same condition. We discussed two kinds of cognitive bias caused by anxiety levels: attentional bias and proportion related bias.

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A Role of Bio-production Robots in Precision Farming Model of Japan

  • Shibusawa S.
    • Agricultural and Biosystems Engineering
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    • v.5 no.1
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    • pp.1-4
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    • 2004
  • Community-based precision farming is a new concept of agricultural systems, which leads to organize groups of wise farmers and technology platforms in Japan. The wisdom farmers create a rational farming system to manage hierarchical variability: variability in farmers' community as well as variability of within-field and between-field. The technology platform develops and provides three key-technologies: mapping technology, variable-rate technology, and decision support systems available for rural constraints. Advancement of bio-production robots leads precision farming to the next level, where two technological innovations: how to produce and manage information-oriented fields and information-added products, can be attained.

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Bioprospecting in a Tropical Dry Deciduous Forest of Western Rajasthan, India

  • Kumar, J.I. Nirmal;Sajish, P.R.;Kumar, Rita.N.;Bhoi, Rohit Kumar
    • Journal of Forest and Environmental Science
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    • v.26 no.1
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    • pp.25-30
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    • 2010
  • Bioprospecting has been widely used to assess the economic potential of different plant species and their value-addition. Prospecting for biological material like plants with medicinal or other economically valuable properties like fibre or oil is becoming a dynamic activity. Our folklore with embedded cultural heritage has tremendous possibilities and potential for bioprospecting. This forest region of Western Rajasthan is enriched with diverse vegetational wealth, if subjected to bioprospecting may prove to be a boon for the society.

White matter injury following rotavirus infection in neonates: new aspects to a forgotten entity, 'fifth day fits'?

  • Yeom, Jung Sook;Park, Chan-Hoo
    • Clinical and Experimental Pediatrics
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    • v.59 no.7
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    • pp.285-291
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    • 2016
  • That rotavirus infection can cause neurological symptoms in young children has been well established. However, it is surprising why rotavirus infection has been overlooked as a cause of neonatal seizures for many years, despite significant research interest in neonatal rotavirus infection. Neonates are the age group most vulnerable to seizures, which are typically attributed to a wide range of causes. By contrast, because rotavirus infection is usually asymptomatic, it has been difficult to identify an association between this virus and neonatal seizures. The conventional wisdom has been that, although neonates are commonly infected with rotavirus, neurological complications are rare in this age. However, recent studies using diffusion-weighted imaging (DWI) have suggested a connection between rotavirus infection and neonatal seizures and that rotavirus infection can induce diffuse white matter injury without direct invasion of the central nervous system. The clinical features of white matter injury in rotavirus-infected neonates include the onset of seizures at days 4-6 of life in apparently healthy term infants. The recent findings seem to contradict the conventional wisdom. However, white matter injury might not be a completely new aspect of rotavirus infection in neonates, considering the forgotten clinical entity of neonatal seizures, 'fifth day fits'. With increased use of DWI in neonatal seizures, we are just starting to understand connection between viral infection and white matter injury in neonates. In this review, we discuss the historical aspects of rotavirus infection and neonatal seizures. We also present the clinical features of white matter injury in neonatal rotavirus infection.

A Study on the Islamic Libraries in the Middle Ages (중세 이슬람 도서관 연구)

  • Yoon, Hee-Yoon
    • Journal of Korean Library and Information Science Society
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    • v.50 no.3
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    • pp.1-22
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    • 2019
  • Western society has depreciated the Middle Ages as the 'Darkness'. However, if Islam, which led the medieval millennium, had not spread paper and art of papermaking, and Arabic translations to the Western countries, translating and interpreting Arabic manuscripts into Greek and Latin, Gutenberg's printing press, Reformation, and Renaissance could not take place. They were not destructors of ancient knowledge and civilization, but were the protagonists of restoration and resurrection. The base camp is the Mosque and Islamic library(the House of Wisdom), which was referred to as a Muslim community. This study traced Islamic libraries that emerged in the process of establishing the Islamic dynasties and controlling Arabian Peninsula, Africa, Iberian Peninsula. For this purpose, the Islamic library was divided into the caliph library led by the royal families, the public library attached to the mosques, and the private library established by the viziers and scholars, etc. Then, the researcher analyzed history and development, roles and functions, impact and Importance on human civilization, and stagnation and decline, focusing on major libraries that existed in the Islamic cities of Damascus, Mecca, Baghdad, Aleppo, Cordoba, Cairo, Fes, Tunis, etc.

Service Philosophy as Wisdom for Human Society Development (인류사회 발전 지혜로서의 서비스철학)

  • Hyunsoo Kim
    • Journal of Service Research and Studies
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    • v.12 no.4
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    • pp.1-18
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    • 2022
  • This study was conducted to prove that the service philosophy is the development principle of human society in the service age. From ancient times to the present, the service philosophy was tried to show the wisdom of the development of human society in all earth spaces including the East and the West. In addition, it tried to prove that the service philosophy was at the center of the development wisdom of many countries and individuals who flickered on all space on earth and all human time. The study showed that the differences between countries were in software rather than hardware. Furthermore, it was analyzed that countries with a service philosophy embedded in the center of software such as spirit and culture made a great contribution to human society. The cases of Greece and Rome, the Republic of Venice, the Republic of the Netherlands, followed by the United States and modern Korea prove this, and the Soviet Union can be seen to disprove it. The former was a society in which state-run software was strong, and the latter was a society in which hardware was strong. There is a big difference between the case of the state, which citizens have autonomously organized and operated, and the case of the upper-level state-led operation. Since the leadership of the upper classes is not based on the service philosophy, the accumulated software power is weak, so it can be said that the accumulation of wisdom in human society is weak. Therefore, while the essence of human society so far has been a society of self-centered animal ecosystems led by selfishness, the human society in the service age from now on can be said to be a society of plant ecosystems where mutual respect and self-centeredness coexist. Just as the society centered on the service philosophy in the past human society prospered and left a greater legacy to mankind, it is suggested that the human society in the future service era should be a human society of a plant ecosystem centered on the service philosophy. Further in-depth studies related to this are needed in the future.

THE ''BAYT AL-HlKMA'' AND SCIENTIFIC ACTIVITY OF CENTRAL ASIAN SCHOLARS IN BAGHDAD

  • ABDUKHALIMOV, BAKHROM
    • Acta Via Serica
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    • v.1 no.1
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    • pp.15-23
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    • 2016
  • The main aim this paper is to investigate the "Bayt al-Hikma" ("The House of Wisdom"), an important medieval centre for translation and science. In this paper, the author attempts to define the establishment, tasks and development of this institution and its place in medieval civilization. In addition, considerable attention is given to the scientific activity of the Central Asian scholars in Baghdad, who migrated there when caliph al-Ma'mun shifted his court from Marw to Baghdad in 819 CE. The paper describes "Bayt al-Hikma" as an important institution for translation and science and describes some of the Central Asian scholars' activities in Baghdad. Despite its brevity, this short overview shows that these scholars had an important influence on the development of medieval sciences.

Technology valuation utilizing crowd sourcing approach (크라우드 소싱 접근법을 활용한 기술가치 평가)

  • Choi, Jieun;Lee, Hwansoo
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.6 no.6
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    • pp.403-412
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    • 2016
  • As transaction and investment using technology are vitalized, the need for objective standards for the technology is increasing. Current technology value evaluation system is limited lacking reliability and objectivity. Besides the traditional evaluation methodology which are market approach, income approach and cost approach other diverse evaluation methodology such as real option method and royalty calculation method are being studied; however currently there are no dominant evaluation methodology in the market. Same value evaluation system cannot be applied between similar technologies because value of technology is relatively decided based on the target. Approaching through collective intelligence and crowd sourcing, in meaning of majority participant's decision can make objective and better result than handful of experts, suggest alternative to problems of such matter above. By grafting the four types of crowd sourcing model which are Wisdom, Voting, Funding and Creation, this paper will discuss the ways to enhance the objectivity of technology evaluation through direct evaluation utilizing expert group and the public's indirect evaluation.

Isolation and characterization of human dental tissue-derived stem cells in the impacted wisdom teeth: comparison of dental follicle, dental pulp, and root apical papilla-derived cells (미성숙 매복지치의 치낭, 치수, 치근유두 조직에서 다능성 줄기세포의 분리와 특성화에 대한 연구)

  • Song, Jung-Ho;Park, Bong-Wook;Byun, June-Ho;Kang, Eun-Ju;Rho, Gyu-Jin;Shin, Sang-Hun;Kim, Uk-Kyu;Kim, Jong-Ryoul
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.36 no.3
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    • pp.186-196
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    • 2010
  • Introduction: The first aim of this study was to isolate the dental tissue-derived stem cells from the dental follicle (DF), dental pulp (DP), and root apical papilla (RAP) of the extracted wisdom teeth. Second was to evaluate their characterization with the expressions of transcription factors and cell surface markers. Finally, their ability of the in vitro multi-lineage differentiations into osteogenic and adipogenic cells were compared, respectively. Materials and Methods: Dental tissues, including dental follicle, dental pulp, and root apical papilla, were separated in the extracted wisdom teeth. These three dental tissues were cultured in Dulbecco’s modified Eagle’s medium (DMEM) with supplements, respectively. After passage 3, the homogeneous shaped dental tissue-derived cells were analyzed the expression of transcription factors (Oct-4, Nanog and Sox-2) and cell surface markers (CD44, CD90 and CD105) with reverse transcription polymerase chain reaction (RT-PCR) and fluorescence-activated cell sorting (FACS) analysis. In order to evaluate in vitro multi-lineage differentiations, the culture media were changed to the osteogenic and adipogenic induction mediums when the dental tissue-derived cells reached to passage 3. The characteristics of these three dental tissue-derived cells were compared with immunohistochemistry. Results: During primary culture, heterogenous and colony formatted dental tissue-derived cells were observed in the culture plates. After passage 2 or 3, homogenous spindle-like cells were observed in all culture plates. Transcription factors and mesenchymal stem cell markers were positively observed in all three types of dental tissue-derived cells. However, the quantity of expressed transcription factors was most large in RAP-derived cells. In all three types of dental tissue-derived cells, osteogenic and adipogenic differentiations were observed after treatment of specific induction media. In vitro adipogenic differentiation was similar among these three types of cells. In vitro osteogenic differentiation was most strongly and frequently observed in the RAP-derived cells, whereas rarely osteogenic differentiation was observed in the DP-derived cells. Conclusion: These findings suggest that three types of human dental tissue-derived cells from extracted wisdom teeth were multipotent mesenchymal stem cells, have the properties of multi-lineage differentiations. Especially, stem cells from root apical papilla (SCAP) have much advantage in osteogenic differentiation, whereas dental follicle cells (DFCs) have a characteristic of easy adipogenic differentiation.