• Natural Product Sciences
• /
• v.21 no.3
• /
• pp.210-218
• /
• 2015

The antioxidant activity of white ginseng was not recorded in Korea Functional Food Code, while its activity of red ginsengs was recorded. The aim of this study was to evaluate the antioxidant and hepato protective effect of different ginsengs in H₂O₂-treated HepG2 cells. White and red ginseng were prepared from longitudinal section of the same fresh ginseng (4-year old). The whole parts of white and red ginsengs were separately extracted with 70% ethanol and distilled water respectively, at 70 ℃ to obtain therapeutic ginseng extracts namely, WDH (distilled water extract of white ginseng), WEH (70% ethanol extract of white ginseng), RDH (distilled water extract of red ginseng) and REH (70% ethanol extract of red ginseng). In this work, we have investigated the DPPH, hydroxyl radical, Fe²⁺-chelating activity, intracellular ROS scavenging capacity and lipid peroxidation of different ginsengs. All these extracts showed a dose dependent free-radical scavenging capacity and a ROS generation as well as lipid peroxidation was significantly reduced by treatment with bioactive extracts of white ginsengs (WDH) than red ginsengs. Additionally, white ginseng extracts (WDH) has dramatically increased intracellular antioxidant enzyme activities like superoxide dismutase and catalase in H₂O₂-treated HepG2 cells. All these results explain that administration of white ginseng is useful as herbal medicine than red ginseng for chemoprevention of liver damage.

• KSBB Journal
• /
• v.15 no.3
• /
• pp.323-328
• /
• 2000

Free amino acids were extracted and analyzed from Korean mountain ginsengs. Chinese mountain ginsengs and Korean white ginsengs by HPLC. The highest total free amino acid content was 12.46 mg/g in Korean white ginseg(P) and the lowest total free amino acid content was 6.86 mg/g in Korean mountain ginseng (Kㅡ6) The content of arginine in a Korean white ginseng(Y) was 8.77 mg/g Arginine was 77.80% of total free amino acids in a Korean mountin ginseng (KM2) The amount of histidine and methionine in Korean mountain ginsengs were higher than any other ginsengs. The highest amount of threonine and lysine were observed in Korean white ginseng and Chinese mountain ginseng respectively, The contents of glycine in Korean mountain ginseng and korean white ginseng were higher than Chinses mountain ginseng. There is no significant difference between two mountain ginsengs and Korean white ginseng.

• Korean Journal of Pharmacognosy
• /
• v.20 no.3
• /
• pp.170-174
• /
• 1989

Crude saponin and ginsenosides in commercial white ginsengs such as six kinds of whole ginsengs, five kinds of tail roots and one undergrade raw ginseng were analyzed. The contents of crude saponin and ginsenosides in whole ginsengs were found to be 2.7 to 4.6% and 1.0 to 1.7%, respectively. On the other hand, those of tail roots were 3.3 to 7.2% and 1.3 to 4.4%, respectively. The content ratio of PD to PT saponin in whole ginsengs showed a little variation as 0.73 to 0.92, while those of tail roots showed a greater variation in the range of 0.72 to 1.75, indicating that tail roots contain higher content of PD saponin than whole ginsengs did.

• Proceedings of the Korean Society for Agricultural Machinery Conference
• /
• 2000.11b
• /
• pp.388-395
• /
• 2000

This study was performed to examine the effects of infrared (IR)/heated-air combination drying on some quality attributes of Korean white ginsengs. Ginseng roots were dried in a dryer where both the far infrared ray and heated-air are available as drying energy sources. Diametral shrinkage, external color, total saponin content, and ginsenosides and free sugar composition of the IR/heated-air combination dried ginsengs were measured and compared with those of commercial white ginseng products. The external color became lower in lightness and higher in saturation as the IR radiating plate temperature increased. IR/heated-air combination dried white ginsengs at IR plate temperature of 100$^{\circ}C$ was comparable to the commercial white ginseng products in color characteristics. Diametral shrinkage ratios ranged from 20 to 36% and appeared to be independent on the different drying methods. No definite evidence could be found whether the IR/heated-air combination drying and the conventional. hot-air drying practice resulted in white ginsengs having different ginsenoside contents and compositions. No conclusion could be made on whether the various drying treatments used in the study had effects on the free sugar contents and compositions of white ginsengs.

• Agricultural and Biosystems Engineering
• /
• v.7 no.1
• /
• pp.8-12
• /
• 2006

This study was conducted to develop a real-time internal quality evaluation technique for Korean red ginseng using NIR spectroscopy while they were moving to be graded. Internal qualities of Korean red ginseng were defined by color, amount of white core and cavity in the red ginseng. To evaluate the internal quality, PLS (Partial Least Square) model was developed. Spectrum saturation can be occurred when most red ginseng has a sound internal quality expressed by higher light transmittance ratio, but that could not found in the ginseng of internal white core under the same light situation. And, if spectrum saturation is obtained, it is hard to identify the exact information of internal quality. In order to evaluate of the internal quality regardless of having internal normal core or white core, an integral time controlled method was used to obtain traditional spectrum. This procedure was applied in real-time process when red ginseng was moving to be graded in the line. Among the 450 samples including 223 internal normal ginsengs and 227 internal white core ginsengs, 315 ginsengs (70%) were used to develop a calibration model and 135 ginsengs were spent to validate the model. The result of quality evaluation by the model was very good showing SEP and bias were 0.3573 and 0.0310, respectively, and the accuracy was 95.6%.

• Preventive Nutrition and Food Science
• /
• v.21 no.1
• /
• pp.24-30
• /
• 2016

Fresh ginseng roots were aged in an oven at $80^{\circ}C$ for 14 d. The in vitro and in vivo antioxidant activities of this aged ginseng, in comparison with those of the white and red ginsengs, were evaluated. In in vitro antioxidant assays, the ethanolic extracts from aged ginseng showed significantly higher free radical scavenging activity and reducing power than those of the white and red ginsengs. In in vivo antioxidant assays, mice were fed a high fat diet supplemented with white, red, or aged ginseng powders. High fat feeding resulted in a significant increase in lipid peroxidation and a substantial decrease in antioxidant enzymes activities in the animals. However, diet supplementation of ginseng powders, particularly aged ginseng, markedly reduced lipid peroxidation and enhanced the antioxidant enzymes activities. The results illustrate that the aged ginseng has greater in vitro and in vivo antioxidant capacity than the white and red ginsengs. The aged ginseng also showed considerably higher total saponin, phenolic, and flavonoid contents, indicating that its antioxidant capacity may have been partly due to its high levels of antioxidant compounds. This new ginseng product may be useful as a functional food with strong antioxidant potential.

• Journal of Ginseng Research
• /
• v.20 no.3
• /
• pp.256-261
• /
• 1996

Comparative biological activities of 70fr methanol extracts from the main roots and rhizomes of both red and white ginsengs were investigated using several in vitro experimental models. The main root of red ginseng and the rhizome of white ginseng strongly inhibited lipld peroxidation of hepatic microsomes induced by the non-enzymatic $Fe^{+}$ / Ascorbate system. The main root and rhizome of red ginseng markedly inhibited the release of G07, GPT and LDH by $CCl_4$-induced cytotoxicity in primary cultured rat hepatocytes as compared with those of white ginseng. And also, the main root of red ginseng showed a slight differentiating activity on HL-60 cancer cell line. The results suggest that the rhizome of ginseng have potential as a source of medicinal crude drug with possible pharmacolobica1 applications .

• Journal of Pharmaceutical Investigation
• /
• v.38 no.1
• /
• pp.23-29
• /
• 2008

Red ginseng is made of white ginseng through the steaming and drying procedure. In this process, the amounts of toxic elements of ginseng are decreased and those of effective components, ginsenosides are increased. In order to identify the components alteration of white ginseng by processing time, we applied HPLC-based metabolomics approach combined with the principal component analysis (PCA) multivariate analysis. White ginsengs were steamed at 0, 1, 2, 4, 8 and 16 h, respectively and followed by drying process at moderate temperature. Then the steamed ginsengs and the commercial red ginsengs were analyzed by HPLC. On the basis of HPLC results, PCA multivariate analysis was applied for evaluating the quality of red ginseng, which showed the processed ginsengs are grouped by processed time because less polar ginsenosides were increased in proportion as the steaming time was increased. The purchased red ginsengs were distributed in the range of $0{\sim}1$ hour steaming time. This pilot experiment suggests that HPLC-based metabolomics approach is able to allow the quality of herbal medicines to be controlled with a simple and economic method.

• Journal of Ginseng Research
• /
• v.22 no.1
• /
• pp.18-21
• /
• 1998

Comparative cytotoxic activities of petroleum ether soluble fraction from various ginsengs of Panax species were evaluated using A549 (human lung adenocarcinoma) and SK-OV-3(human ovary carcinoma) cancer cell lines. Korean red ginseng, Korean white ginseng, American ginseng and Canadian ginseng were found to show more potent cytotoxicitles on A549 and SK-OV-3 cell lines than Chinese red ginseng, Japanese red ginseng and Sanchi ginseng. It is noteworthy that especially, red ginseng prepared from the root of Panax ginseng cultivated in Korea shows relatively stronger cytotoxic activities than those cultivated in China and Japan.

• YAKHAK HOEJI
• /
• v.22 no.4
• /
• pp.242-249
• /
• 1978

We have compared the panaxadiol and panaxatriol contents of white ginsengs from different countries and red ginseng, by using gas and high-pressure liquid chromatographies. Oleanolic acid contents in various ginseng species were compared by gas liquid chromatography and densitometry. Korean ginseng was found to contain greater amount of panaxadiol and panaxatriol than those of any other countries. The ginsengs from other countries, especially Chikusetzu ginseng, were found to contain far greater amount of oleanolic acid than Korean ginseng.