• Biomolecules & Therapeutics
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• v.15 no.2
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• pp.83-88
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• 2007

The roots of Liriope platyphylla (Liliaceae) are widely used in traditional Chinese medicine. In the present study, we investigated the effects of ethanol (70%) extract of the roots of Liriope platyphylla (ELP70) on learning and memory using behavioral and immunohistochemical methods in mice. Control animals were treated with vehicle (10% Tween 80). With sub-chronic treatments of ELP70 (p.o.) for 14 days, the latency time was significantly increased compared with that of the vehicle-treated control group (50, 100 and 200 mg/kg; P<0.05). Moreover, immunopositive cells for brain derived neurotrophic factor (BDNF) were significantly increased in the hippocapmpal dentate gyrus and CA1 regions after ELP70 treatments for 14 days (50, 100 and 200 mg/kg; P < 0.05). In addition, those cells for nerve growth factor (NGF) were also increased in the hippocapmpal dentate gyrus region (50, 100 and 200 mg/kg; P<0.05). These results suggest that the sub-chronic administration of ELP70 improves learning and memory, and that their beneficial effects are mediated, in part, by the enhancement of BDNF or NGF expression.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.8 no.3
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• pp.151-160
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• 2014

In this study, the effect of the automotive haptic-seat technology which can transmit the driving information by the vibro-stimulus from the seat was investigated to overcome previous system's limitation relied on the visual and audial method and to help handicap driving. A prototype haptic seat cover with 30 coin-type motors and driver module were developed for this sake. In an experiment of seat vibration stimulation being performed under virtual driving situation by targeting the elderly aged over 65 years old, average score of test subjects for total vibration recognition was 3.5/4 points and recognition rate of 87.5% was represented. In addition, a result that all the test subjects totally recognized overspeed warning signal of 4 times was represented. As a result of statistical analysis for vibration recognition score by each group depending on TMT score, a significant difference was not found and a result that tactile function of which vibration is recognized even by the aged whose visual, perceptional function is declined showed an equal ability was obtained.. In this study it was shown that the seat vibration stimulus could be used to transfer the old drivers' information while driving.

• Korean Journal of Health Education and Promotion
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• v.23 no.3
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• pp.65-83
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• 2006

Objectives: This is one of the first efforts to describe incidence of alcohol-related problems and to identify environmental correlates associated with them among colleges. Methods: Date were collected by a sample of 105 college administrators who are in charge of student affairs in colleges nationwide through self-administrated questionnaire. Both logistic and linear multiple regression analyses were employed to identify the correlates associated with alcohol-related problems. Results: Most of colleges(76.6%) under study reported to have at least one alcohol-related problem in previous years. Interpersonal violence was alcohol-related problem taken placed most frequently, followed by making noise episode, having property damaged and motor vehicle accidents. Logistic regression analysis identified factors associated with incidents of alcohol related problems. They included being private colleges, numbers of prevention activities, product promotion and marketing by alcohol industry and alcohol accessibility to drinking context. Multiple regression analyses showed that correlates associated with numbers of alcohol-related problems included being a private college, being located in rural area, having drinking density, product promotion and availability of alternative activities to drinking. Conclusions: Environmental correlates were associated with incidence of alcohol related problems in colleges nationwide. Policy implications were discussed.

• The Journal of the Acoustical Society of Korea
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• v.19 no.6
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• pp.3-9
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• 2000

The Bell King Songdok the Great tolls magnificient sound that would be a great vehicle which brings all beings to the Sutras. Since 693, there was a magic flute, MANPASIKJUK, which was in existence in Shilla Dynasty that could lull all the evil-wawes, such an plaques, storms, Droughts, Famines and even Enemies. Thus, a sound tube, MANPASIKJUK, was erected in the crown of the Bell Songdok the Great so as to be effective to emit the nominal frequency tone whenever the Bell tolls for the national prosperity and welfare the People. Therefore, the Bell makers tried to fine the transmissibility condition through the sound tubr, several times during 34 years, However, it seems to be unfinished. Ever since, all of the korean Brahman Bell have the sound tubes of MANPASIKJUK, but none is performed their own functions. Here, one of the way to let the function of the sound tube of MANPASIKJUK out in the Bell Songdok the Great is proposed. There are two steps: the 1st is to elongate 18cm to the present length 77cm to fulfill the transmissibility condition for the nominal frequency of sound is emitted through the corrected sound tybe. 2nd step is to rise to 95% of the emission of the tone of nominal frequency, so that an exponential hem with the flare constant 2.8m-1, length 2.259m and the radius of the mouth 1.772m is to be extended to the corrected sound tube.

• Food Science of Animal Resources
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• v.24 no.4
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• pp.424-432
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• 2004

The handling and transport of broiler birds from farm to the processing factory is known to cause injury and dead. The preslaughter period can be compromised through thermal stress, emotional stress, starvation, dehydration, metabolic exhaustion, trauma to the skin and bone fraction resulting in bruising and dead. This paper focuses on the control points of individual post Harvest stages by reference to recent literature. In catching, the injuries and deads are caused from fracture of bone, skin damage and hipbone dislocation. It can be improved by training the catchers. The primary factor of dead during transportation is from thermal stress. It is related to stocking density, type of crate and vehicle, ventilation and transportation time. Of the factors, the ventilation is very important. The holding place should be built with consideration of protection from the hostile external environment. There were not much progresses in this area, however, many researches are conducting to focus on animal welfare in European Union. Recently, it is rapidly changed in marketing custom from whole carcass to portion cut in Korea. This means the increase of economic loss due to the mishandling at post harvest. The systematic approach is demanded for this area.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.48 no.2
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• pp.106-116
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• 2011

USN(Ubiquitous Sensor Network) environment permits us to access whatever information we want, whenever we want. The technologies to provide a basement to these environments premise an accurate location establishment. Especially, ITS(Intelligent Transportation Systems) is easily constructed by applying USN technology. Localization can be categorized as either Range-based or Range-free. Range-based is known to be not suitable for the localization based on sensor network, because of the irregularity of radio propagation and the additional device requirement. The other side, Range-free is much appropriated for the resource constrained sensor network because it can actively locate by means of the communication radio. But, generally the location accuracy of Range-free is low. Especially, it is very low in a low-density environment. So, these two methods have both merits and demerits. Therefore, it requires a new method to be able to improve tracking accuracy by combining the two methods. This paper proposes the tracking scheme based on range-hybrid, which can markedly enhance tracking accuracy by effectively using the information of surrounding nodes and the RSSI(Received Signal Strength Indication) that does not require additional hardware. Additionally, we present a method, which can improve the accuracy of vehicle tracking by adopting the prediction mechanism. Simulation results show that our method outperforms other methods in the transportation simulation environment.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.5 no.1
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• pp.17-25
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• 2011

This paper aims to find the optimal control gain for enhancing the convenience of electric walking frames and design a control algorithm. With the recent advances in medical technology, there has been a rapid increase in the aging population and a variety of mobile walking frames have been developed for improvement of the quality of life. However, the manual walking frames of such mobile aids don't have any electric motor which helps facilitate elderly users' walking and thus are not efficient enough for the old people of weak strength to use especially when moving on uneven surfaces such as slopes or thresholds. The types of electric walking frames have been developed to overcome such inefficiency. Electric walking frames require users' control operations for motor driving unlike manual frames. Therefore, when they are not properly handled, it causes considerable inconvenience to their users. The present study compared the electric walking frames with manual ones in terms of operational convenience and attempted to improve the user convenience of walking frames varying the control value for user convenience based on certain standards. This paper presented a haptic sensor designed to recognize the will to walk and measure the degree of convenience and proposed a control algorithm for improvement of convenience. For user convenience, this paper evaluated the relative convenience of walking frames in view of changing differences between the center of vehicle (COV) and the center of position (COP). With the employment of an electric walking frame and a new measuring method, all the processes were experimentally tested and validated.

• Journal of the Korea Convergence Society
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• v.8 no.2
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• pp.253-258
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• 2017

Urbanization, industrialization, and informatization raised quality of life in modern society. However, many people face with social maladjustment phenomena of human alienation and loss of true self due to mechanization, competition and stress. To alleviate the social maladjustment, people should look for their true self and the self. Drinking tea may play an important role in bringing your true self and the self and be a vehicle for them to meet in daily life. Therefore, this study uses the standard web protocol technology to popularize the True Self Tea Ceremony which helps to enhance true self and self-respect. The True Self Tea Ceremony uses the basic utensils. The paper proposes the popularization of the True Self Tea Ceremony using the standard web protocol technology. Using the standard web protocol technology enhances the accessibility of users.

• International Journal of Industrial Entomology and Biomaterials
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• v.33 no.2
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• pp.85-91
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• 2016

Exosomes are homogenous vesicles of 40-100 nm diameter produced endogenously. Exosomes are generated by inward budding into multi-vesicular bodies (MVB) and then released to extracellular space. Exosomes contain various nucleic acid and protein cargoes from their cells of origin and this endosomal cellular molecules are used for intracellular communication and for both promotion and suppression of immune responses. Recently, they are also considered as delivery vehicle for therapeutic proteins due to their characteristics of stability in body fluids and ability for target uptake. Also, they show less immune reactivity because the isolated exosome harboring therapeutic proteins can be from the same host. White-spotted flower chafer, Protaetia brevitarsis is one of the major insect commercially reared in Korea. There are bacterial and fungal pathogens causing diseases in the beetle, and these diseases incur economic loss to the larva-rearing farms. Due to their endosomal cargoes, exosomes are good candidates in use of disease diagnosis. In this study, we isolated insect exosome from the hemolymph of P. brevitarsis, and verified it by analysis of the exosome-specific surface proteins and RNA.

• Korean Journal of Community Nutrition
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• v.11 no.2
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• pp.240-252
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• 2006

A survey was implemented to suggest basic data for assuring the safety of cooked foods in foodbank operations. A questionnaire consisted of total 48 items including general characteristics, basic inputs and perceived importance/performance of sanitary management. One hundred twenty-eight responses among the 267 nationwide foodbanks were used for the statistical analysis. About forty-one percent of foodbanks was operated a period of 1-3 years and 43.0% of them were managed by social welfare organizations. The number of staff was only 0.5 person per operation with the whole responsibility and 1.0 with additional work, and thus most of the work was managed by volunteers. Job satisfaction was shown to be moderate and was affected by specialty and salary mostly. The facilities and equipment in foodbanks were not enough to operate and freezers/refrigerators were the top priority to supplement. Most of the respondents attended a nationwide level sanitary education program (79.7%); but complained not enough frequency of education (90%). The sanitary status of the donated foods was considered as satisfactory but some safety practices had to be improved, including personnel expenses and operating costs in the district level, a sanitary awareness of the donors and a general management of the facilities arid equipment. An assessment on sanitary management resulted in an overall average of 4.45 out of 5 points in importance and 3.85 in performance showing the high level of sanitation perception in foodbank managers. From the IPA analysis, the fields found to be improved were sanitation management during cooking and temperature control as well as cleanliness and sanitation of both transport vehicle and refrigerator/freezer. To secure the food safety in foodbanks, consequently, personnel support, supplement of facilities and equipment, intense sanitation education and development of sanitation management program is needed.