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Superhongmi bran extract improves lipid profile and menopause symptoms: a randomized, placebo-controlled clinical trial (슈퍼홍미 미강 추출물의 폐경 후 여성의 혈중 지질 농도 및 대사성 질환 개선 효과)

  • Chung, Soo Im;Nam, Su Jin;Liang, Jie;Ma, Jing Wen;Kang, Mi Young
    • Korean Journal of Food Science and Technology
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    • v.51 no.2
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    • pp.182-187
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    • 2019
  • Women who undergo natural menopause transition have increased numbers of risk factors relating to metabolic syndrome due to estrogen deficiency. This study was conducted to investigate the effect of Superhongmi bran extract on metabolic syndrome improvement in menopausal women. Thirty women, who participated in a randomized, double-blind, placebo-controlled trial, were assigned to placebo-control (n=15) or Superhongmi bran extract (n=15) groups and were asked to consume two tablets (350 mg per extract per tablet) per day. After 12 weeks, weight, body mass index (BMI), plasma triglyceride (TG) levels, and total cholesterol (TC) levels were significantly decreased, whereas HDL-cholesterol (HDL-C), apolipoprotein A1 (ApoA1), adiponectin, superoxide dismutase 1 (SOD1), and GSH (glutathione) concentrations were significantly increased in the Superhongmi bran extract group. Moreover, $17{\beta}-estradiol$, and progesterone levels in the Superhongmi group were significantly higher than those in the placebo-control group. These results suggest that Superhongmi bran extract alleviates metabolic symptom in menopausal women.

The analysis of Factors associated with the Health Examination expenditure in a General Hospital based on the cased (일개 종합병원 종합(민간)검진 비용 영향요인 분석)

  • Lim, Ji Hyun;Suh, Won Sik
    • Korea Journal of Hospital Management
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    • v.25 no.4
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    • pp.76-93
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    • 2020
  • Purpose: In this study, the general characteristics of subjects who spent more than a certain amount of cost for general medical examination at the general hospital health promotion center, and the characteristics of disease, family history, and lifestyle (smoking, alcohol, physical activity, oral care) significantly differed in cost expenditure. We intend to provide basic data for establishing an appropriate marketing strategy for comprehensive examination. Method: It was conducted for users who received comprehensive checkups at a health promotion center at a general hospital in Seoul. The research data collection period is for 979 people who performed comprehensive examinations from January 2019 to December 2020. In order to carry out a comprehensive examination, a questionnaire before the examination was distributed to the subjects who visited the hospital to prepare, and the investigation was conducted in a way that the subjects of the investigation directly filled in. Results: There was a significant influence on the difference in expenditure for comprehensive examination according to the gender, age, and type of health insurance of the subject. In addition, there were significant differences in expenditure according to the presence or absence of disease and the type of family history. Weight loss, smoking history, smoking period, smoking frequency, drinking history, and drinking frequency all had significant effects on cost expenditure. Also, strength training and oral treatment management showed a significant effect on the cost of comprehensive examination. The number of flossing and interdental brushing was also found to have a significant effect. According to the results of multiple regression analysis, disease history (t=2.683, p<.01) and mean smoking frequency (t=4.315, p<.001) appeared to have the most significant effect on expenditure statistically. In other words, when the subject has a history of disease and when the average number of smoking is large, it means that the comprehensive examination cost is remarkably large. Conclusion: By using these contents, hospitals can further refine the marketing of the examination center. In addition, a more convenient and specialized process should be used by patients by linking the general medical department and the examination center well. In terms of management of operating medical institutions, this can be expected to create patients and increase profits.

Preventive Dimension of Confucian Morality regarding Adolescent Deviation (청소년 일탈에 대한 유교 도덕의 예방적 차원)

  • Shin, Chang Ho;Choi, Seung Hyun
    • The Journal of Korean Philosophical History
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    • no.27
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    • pp.417-446
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    • 2009
  • This study was to review the features of the preventive dimension in connection with adolescent deviation on the basis of the morality and ethics held by Confucian doctrine. To find solutions to the problems of adolescent deviation is never easy. As adolescent deviation always does occur, it is important to consider the methods that can minimize and prevent it. The traditional society of Korea laid weight on the education and training in the aspect of preventive measure against such adolescent deviation by emphasizing moral edification and realization of spiritual understanding for it. In this paper, the researcher tried to understand the problem situations by examining the image of such deviation and its type as well as the method on response thereto targeting the young generation of Korea. In addition, the researcher analyzed how the adolescent was recognized in the traditional society that was established on the Confucian values, and moral standards that applied to them, and the process of education as well. Through the moral concepts of Confucianism that were revealed in the Doctrine of the Mean (中庸, pronounced 'Jungyong' in Korean) in particular, the researcher sought the possibility of education on morality and ethics that will be able to prevent adolescent deviation. This study suggests that the morality and ethics held by Confucian doctrine can prevent adolescent deviation and open a new horizon of ethics education.

Toxicity of Organophosphorus Flame Retardants (OPFRs) and Their Mixtures in Aliivibrio fischeri and Human Hepatocyte HepG2 (인체 간세포주 HepG2 및 발광박테리아를 활용한 유기인계 난연제와 그 혼합물의 독성 스크리닝)

  • Sunmi Kim;Kyounghee Kang;Jiyun Kim;Minju Na;Jiwon Choi
    • Journal of Environmental Health Sciences
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    • v.49 no.2
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    • pp.89-98
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    • 2023
  • Background: Organophosphorus flame retardants (OPFRs) are a group of chemical substances used in building materials and plastic products to suppress or mitigate the combustion of materials. Although OPFRs are generally used in mixed form, information on their mixture toxicity is quite scarce. Objectives: This study aims to elucidate the toxicity and determine the types of interaction (e.g., synergistic, additive, and antagonistic effect) of OPFRs mixtures. Methods: Nine organophosphorus flame retardants, including TEHP (tris(2-ethylhexyl) phosphate) and TDCPP (tris(1,3-dichloro-2-propyl) phosphate), were selected based on indoor dust measurement data in South Korea. Nine OPFRs were exposed to the luminescent bacteria Aliivibrio fischeri for 30 minutes and the human hepatocyte cell line HepG2 for 48 hours. Chemicals with significant toxicity were only used for mixture toxicity tests in HepG2. In addition, the observed ECx values were compared with the predicted toxicity values in the CA (concentration addition) prediction model, and the MDR (model deviation ratio) was calculated to determine the type of interaction. Results: Only four chemicals showed significant toxicity in the luminescent bacteria assays. However, EC50 values were derived for seven out of nine OPFRs in the HepG2 assays. In the HepG2 assays, the highest to lowest EC50 were in the order of the molecular weight of the target chemicals. In the further mixture tests, most binary mixtures show additive interactions except for the two combinations that have TPhP (triphenyl phosphate), i.e., TPhP and TDCPP, and TPhP and TBOEP (tris(2-butoxyethyl) phosphate). Conclusions: Our data shows OPFR mixtures usually have additivity; however, more research is needed to find out the reason for the synergistic effect of TPhP. Also, the mixture experimental dataset can be used as a training and validation set for developing the mixture toxicity prediction model as a further step.

Effect of Heat Stress of Extreme Heat Lever on Muscle functionand Muscle Injury Markers in Elderly Women (열 스트레스가 여성노인들의 근기능 및 근손상에 미치는 영향)

  • Park, Sok;Lee, Chone Ho;Back, Seung Ok;Shin, Yong Up;Kim, Jung Suk;Cho, Young Wung;Lee, Young Jun
    • 한국노년학
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    • v.30 no.3
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    • pp.793-802
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    • 2010
  • The purpose of this study was to examine the influence of extreme heat on muscle function and muscle injury marker in elderly women. The subjects of this study were eight post-menopausal elderly women without any metabolic disease. All eight subjects were asked to perform the knee joint isokinetic exercise using isokinetic equipment (cybex) in the laboratory and experimental temperature within laboratory was adjusted to two conditions: extreme heat temperature(33±0.5℃) and normal temperature(20±0.5℃) maintained in 50±3% humidity conditions. Each experimental exercise was monitored and analyzed the change of HSP70, LDH and CK. Muscular functions (peak torque, total work, percentage of peak torque body weight, fatigue index, average power and total work) were significant differences at exercise between temperatural conditions (p<.05). In extreme heat temperature, muscular injury markers (HSP70, LDH and CK) were increased, threfore resulted in significantly higher than normal temperature(p<.05). These results show that extreme heat temperature can decrease muscle function in elderly women.

A Study on Forecasting of the Manpower Demand for the Eco-friendly Smart Shipbuilding (친환경 스마트 선박 인력 수요예측에 관한 연구)

  • Shin, Sang-Hoon;Shin, Yong-John
    • Journal of Korea Port Economic Association
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    • v.39 no.2
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    • pp.1-13
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    • 2023
  • This study forecasted the manpower demand of eco-friendly smart shipbuilding, whose importance and weight are increasing according to the environmental regulations of the IMO and the spread of the 4th industrial revolution technology. It predicted the shipbuilding industry manpower by applying various models of trend analysis and time series analysis based on data from 2000 to 2020 of Statistics Korea. It was found that the prediction applying geometric mean had the smallest gap among the trend and time series analysis methods in comparing between forecast results and actual data for the past 5 years. Therefore, the demand for manpower in the shipbuilding industry was predicted by using the geometric mean method. In addition, the manpower demand of smart eco-friendly ships wast forecasted by using the 2018 and 2020 manpower survey results of the Ministry of Trade, Industry and Energy and reflecting the trend of manpower increase in the shipbuilding industry. The result of forecasting showed that 62,001 person in 2025 and 85,035 people in 2030. This study is expected to contribute to the adjustment of manpower supply and demand and the training professional manpower in the future by increasing the accuracy of forecasting for high value-added eco-friendly smart ships.

Investigations of the Potential Fisheries Resources in the Southern Waters of Korea - Biological Composition of Demersal Trawl Catches - (한국 남해안의 잠재어업자원 조사연구 - 저층크롤 어획량의 생물학적 조성 -)

  • Lee, Dae-Jae;Kim, Jin-Kun;Shin, Hyong-Ho
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.34 no.3
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    • pp.241-258
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    • 1998
  • The experimental demersal trawl surveys to provide the essential information for the assessment, management and utilization of commercially important fish stocks in the southern waters of Korea were carried out during five research cruises between October 1996 and October 1997 by the training ship “KAYA” of Pukyong National University. The biological sampling was conducted by using the trawl net with a cover net of 36 mm in mesh size at 64 planned trawl stations during daylight to identify the biological characteristics of fish. Each catch was standardized into catch per unit of time and the catches at each trawl station were sorted, weighed and counted by species. The changes in catches of each fish species and the shifts in dominant species by seasions and sampling regions in the research area were analyzed, and the abundance of fish was estimated from the relationship between the trawl catches and the volume of the water column sampled by demersal trawls. The results obtained can be summarized as follows : 1. During the 64 demersal trawls conducted in the southern waters of Korea, 129 species including 112 species of fishes, 8 species of Cephalopoda and 7 species of Crustacea, were identified Also, during the 1996 and 1997 trawl surveys in the reseach area, a large number of commercially important species with small differences in proportion was found. me proportion of Japanese horse mackerel which comprised 19.8% of the total catch by weight was highest, followed by chub mackerel(15.0%), swordtip squid(9.0%), redwing searobin(6.2%), konoshiro gizzard shad(6.1%), Japanese flying squid(5.8%), silver pomfet(5.1%), blackmouth goosefish(5.1%), etc. Swordtip squid, Japanese flying squid, blackmouth goosefish and blackthroat seaperch were among the dominant species in all seasons with a relatively high and stab1e proportion(3.6~9.0%), and were widely distributed in the entire southern water of Korea. 2. The catch rates by cover net varied at 0.7~91.9% by weight of the total trawl catch by codend and cover net at 64 planned trawl stations and the mean catch rate was 44.4%. Species comprising a major portion of the catches by cover net mainly were swordtip squid, konoshiro gizzard shad, the juveniles of Japanese horse mackerel, blackthroat seaperch and chub mackerel, etc. 3. The distribution density of fish in terms of biomass per unit volume which derived from the catch data by 63 bottom trawl hauls in the southern waters of Korea ranged from 17.9 $\times$ 10-6 to 1,440.9 $\times$ 10-6kg/m3 with the mean value of 153.8 $\times$ 10-6 kg/m3. These fish densities varied between seasons, location of sampling stations and sea conditions. From these results, it is worth noting that the catch composition of multispecies and the increased occurrence of small fish in the southern waters of Korea may also result in new problems in determining the total allowable catch(TAC) levels for economically important species.

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Effect of Stem Number on Growth, Fruit Quality, and Yield of Sweet Peppers Grown in Greenhouses under Supplemental Lighting with High Pressure Sodium Lamps in Winter (겨울철 고압나트륨등 보광 하에서 온실재배 파프리카의 줄기 유인 수가 생육, 과실 품질 및 생산량에 미치는 영향)

  • Yoon, Seungri;Kim, Jin Hyun;Hwang, Inha;Kim, Dongpil;Shin, Jiyong;Son, Jung Eek
    • Journal of Bio-Environment Control
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    • v.30 no.3
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    • pp.237-243
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    • 2021
  • The objective of this study was to evaluate the effect of stem number on plant growth, fruit quality, and yield of sweet peppers grown in greenhouses under supplemental lighting in winter. The seedlings were transplanted at 3.2 plants·m-2 on October 26, 2020, and started supplemental lighting with 32 high pressure sodium lamps for 16-hour photoperiod from December 1, 2020 to May 25, 2021. Stems were differently trained with 2 and 3 numbers after branching nodes were developed. In the final harvest, the plant height was significantly shorter in the 3 stem-plants than in the 2 stem-plants. The number of nodes per stem and the leaves per plant were increased in the 3 stem-plants than in the 2 stem-plants, while the leaf area was less affected. There were no significant differences in the dry mass of leaves, stems, and immature fruits between the 2 and 3 stem-plants. The fruit fresh weight and fruit dry weight in the 3 stem-plants were decreased by 17% and 12% at 156 days after transplanting (DAT), and by 17% and 15% at 198 DAT compared to those in the 2 stem-plants, respectively. The marketable fruit rates were 93.6% and 95.4% in the 2 and 3 stem-plants, respectively. The total fruit yield in the 3 stem-plants was increased by 30.2% as compared to that in the 2 stem-plants. We concluded that the 3-stem-training cultivation positively affected the total fruit yield by sustaining adaptive vegetative growth of the plants. This result will help producers make useful decisions for increasing productivity of sweet peppers in greenhouses.

The Effect of Elastic Band Exercise Training and Detraining on Body Composition and Fitness in the Elder (탄력밴드 운동이 노인의 신체조성과 체력에 미치는 지속적 효과)

  • So, Wi-Young;Song, Misoon;Cho, Be-Long;Park, Yeon-Hwan;Kim, Yeon-Soo;Lim, Jae-Young;Kim, Seon-Ho;Song, Wook
    • 한국노년학
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    • v.29 no.4
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    • pp.1247-1259
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    • 2009
  • Muscle mass is reduced by aging. There seems to be no direct relationship between sarcopenia(muscle loss) and medical cost in the elderly, but lowering muscle mass results in increase risk of fall and decrease of strength, fitness, physical activity, and independent life. This is coupled with physical trouble and chronic degenerative disease such as diabetes, obesity, hyperlipidemia, and hypertension. Thus, sarcopenia is potential risk factor increasing mortality. The purpose of this study was to investigate the effects of elastic band exercise and detraining on sarcopenia prevention related variables, body composition and fitness. The subject of this study was 60~70 aged 14 seniors who participated in exercise program in J-welfare senior center at J-gu in S-city. Elastic band exercise was performed twice per week for 12 weeks. The body composition and fitness variables were measured before 12 weeks of control, after control(before exercise), after 12 weeks of exercise(before detraining), and after 12 weeks of detraining. There was no significant difference in body composition and fitness variables before and after 12 weeks of control, but elastic band exercise before and after 12 weeks has effect on body composition variables such as weight (t=2.978, p=0.001), body mass index (t=3.502, p=0.004), percent body fat (t=2.216, p=0.045), muscle mass (t=-3.837, p=0.002), visceral fat area (t=5.186, p<0.001), and waist-hip ratio (t=3.045, p=0.009) and on fitness variables such as 2-minutes step (t=-6.891 p<0.001), arm curl (t=-4.702, p<0.001), chair stand (t=-4.860, p<0.001), chair sit and reach (t=-5.910, p<0.001), back scratch (t=-3.835, p=0.002), and 8-ft up and go (t=7.560, p<0.001). This exercise effect was continued after 12 weeks of detraining on body composition variables such as weight (t=2.323, p=0.037), body mass index (t=2.503, p=0.026), muscle mass (t=-3.137, p=0.008) and on fitness variables such as 2-minutes step (t=-6.489 p<0.001), chair stand (t=-4.694, p<0.001), chair sit and reach (t=-3.690, p=0.003), and 8-ft up and go (t=7.539, p<0.001). It was found that the elastic band exercise has positive effect on body composition and fitness in the elderly and the effect was maintained over 12 weeks of detraining.

Age difference in association between obesity and Nutrition Quotient scores of preschoolers and school children (어린이 영양지수로 살펴본 유아와 초등학생의 식행동과 비만 사이의 관련성에 있어서 연령의 차이)

  • Bae, Joo-Mee;Kang, Myung-Hee
    • Journal of Nutrition and Health
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    • v.49 no.6
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    • pp.447-458
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    • 2016
  • Purpose: This study was conducted among 235 children aged 3 up to 11 yrs to examine the relationship between subjects' eating behaviors and obesity. Methods: The subjects were divided into three age groups: preschoolers aged 3 to 5 yrs, early elementary school students aged 6 to 8 yrs, and late elementary school students aged 9 to 11 yrs. As a tool for eating behaviors, the recently developed nutrition quotient (NQ) questionnaire was utilized. By age group, scores were gathered and calculated in the five factors, "Balance", "Diversity", "Moderation", "Regularity", and "Practice", which make up the NQ scores. Results: The NQ scores among those aged 3 to 5, 6 to 8, and 9 to 11 yrs did not exhibit any significant differences. Among the scores for the five factors of the NQ, the Diversity scores of those aged 9 to 11 yrs were significantly higher than the scores of those aged 3 to 5 and those aged 6 to 8 yrs. The scores of those aged 3 to 5 and those aged 6 to 8 yrs were higher than the scores of those aged 9 to 11 yrs in Moderation and Regularity. When the subjects were divided into loww-eight/normal and overweight/obese groups, among those aged 6 to 8 yrs, the NQ scores, Moderation, Regularity, and Practice scores were higher in the overweight/obese group than those in the low-weight/normal group. Among those aged 9 to 11 yrs, the overweight/obese group scored higher than the low-weight/normal group only in the Moderation component. Conclusion: From the results, to prevent obesity in elementary school students, it is practical to focus on training related to eating behavior items included in the Moderation component. Furthermore, personalized instructions on eating behaviors and nutritional education based on age are necessary to prevent obesity in children.