• Asian-Australasian Journal of Animal Sciences
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• 제9권6호
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• pp.651-654
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• 1996

The effect of guanethidine on feeding behavior was investigated in the chicken. Graded levels of chronically administered guanethidine, an adrenergic neurone blocker, at 0, 25, 50 and 100 mg/kg body weight, decreased body weight gain and food intake in a dose dependent manner. The effect of acute guanethidine administration on crop emptying rate of the chicken was also investigated. The highest level (10 mg i.v./kg body weight) of guanethidine significantly delayed crop emptying compared with the control. These results suggest that the sympathetic nervous system in the chicken is an important factor for the regulation of feeding behavior associated with food passage from the crop.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2000년도 봄 학술발표회논문집
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• pp.222-229
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• 2000

Malty bridges are severely damaged by the overloaded heavy vehicle and tile trend will become more serious because the traffic volume is continuously increasing. Currently, the vehicles with gross weights over 40 tons or axle weight over 10 tons are not allowed on the public road. However, this regulation is not based on a systemetic study on the bridge capacityand assumed to be much too conservative depending on the vehicle types ans bridge types. In this study, the permit weights of heavy vehicles of diverse axle spacings and axle load distribution are calculated considering the structural characteristics of bridge superstructures. In order to consider the various load effects of heavy weight vehicle crossings, three conditions are considered in the calculation of permit vehicle load. From the results, the permit vehicle weights of bridges are calculated and simplified formulas which can be used in the case when only the vehicle dimension are known are presented.

• Tuberculosis and Respiratory Diseases
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• 제38권3호
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• pp.228-235
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• 1991

Pulmonary surfactant is a lipoprotein complex composed primarily of phospholipid and lungspecific apoproteins that reduces surface tension in the alveolus and maintains alveolar stability at low lung volume. Three families of lung-specific apoproteins have been described: SP-A, a glycoprotein with a reduced molecular weight of 28~36 KDa. SP-B a hydrophobic protein with a nonreduced molecular weight of 18 KDa, and SP-C a hydrophobic protein with a non-reduced molecular weight of 5~8 KDa. Surfactant proteins have important roles in regulating surfactant metabolism as well as in determining its physical properties. The synthesis of the active surfactant peptides appears to be modulated by system with considerable complexity, including numerous levels of regulation such as cell-specific, hormonal and developmental controls. Endotoxin appears to alter surfactant protein mRNAs differentially. It is hoped that the elucidation of the factors controlling the synthesis and metabolism of the surfactant proteins will aid in understanding the pathogenesis of hyaline membrane disease and offer new avenues for the therapy and diagnosis of ther pulmonary disorders as well.

• 한국국방경영분석학회지
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• 제25권1호
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• pp.75-86
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• 1999

The selection criteria of an Authorized Stockage List (ASL) in the Army is based on Army Regulation(AR)409. However, the current selection method of ASL is not considered in cost, weight and volume of repair parts. This paper is focused on developing for a new selection model taking account of cost, weight and volume of repair parts. Goal programming is utilized in order to consider weighted priorities. Different units of cost, and volume are normalized for using weighing value. Real data of a field division are applied to the model. Results of the new selection model are more reduced in cost, weight and volume than those of the previous method.

• The Korean Journal of Physiology and Pharmacology
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• 제16권3호
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• pp.181-186
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• 2012

Fenofibrate is a selective peroxisome proliferator-activated receptor ${\alpha}$ ($PPAR{\alpha}$) activator and is prescribed to treat hyperlipidemia. The mechanism through which $PPAR{\alpha}$ agonists reduce food intake, body weight, and adiposity remains unclear. One explanation for the reduction of food intake is that fenofibrate promotes fatty acid oxidation and increases the production of ketone bodies upon a standard experimental dose of the drug (100~300 mg/kg/day). We observed that low-dose treatment of fenofibrate (30 mg/kg/day), which does not cause significant changes in ketone body synthesis, reduced food intake in Long-Evans Tokushima (LETO) rats. LETO rats are the physiologically normal controls for Otsuka Long-Evans Tokushima Fatty (OLETF) rats, which are obese and cholecystokinin (CCK)-A receptor deficient. We hypothesized that the reduced food intake by fenofibrate-treated LETO rats may be associated with CCK production. To investigate the anorexic effects of fenofibrate in vivo and to determine whether CCK production may be involved, we examined the amount of food intake and CCK production. Fenofibrate-treated OLETF rats did not significantly change their food intake while LETO rats decreased their food intake. Treatment of fenofibrate increased CCK synthesis in the duodenal epithelial cells of both LETO and OLETF rats. The absence of a change in the food intake of OLETF rats, despite the increase in CCK production, may be explained by the absence of CCK-A receptors. Contrary to the OLETF rats, LETO rats, which have normal CCK receptors, presented a decrease in food intake and an increase in CCK production. These results suggest that reduced food intake by fenofibrate treatment may be associated with CCK production.

• 대한조선학회논문집
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• 제33권4호
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• pp.97-105
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• 1996

선체 중량이 최소가 되는 설계를 수행하기 위해서는 선체 중량이 최소가 되는 tank 배치의 결정이 선행되어야 하며, 결정된 tank 배치 내에서 선체 중량이 최소가 되는 구조 부재의 배치 및 치수를 결정하여야 한다. 선체 중량이 최소가 되는 tank 배치를 하기 위하여 저자들에 의해 개발된 선급 규정에 의한 종강도 부재의 최소 중량 설계 프로그램과 일반화 경사처짐법에 의한 횡강도 부재의 최소 중량 설계 프로그램을 결합하여 화물창부의 선각 중량을 구하였으며, 중량 추정 공식에 의해 횡격벽 및 선수미부 등의 중량을 구함으로서 선체 전체의 최소 중량 설계 프로그램을 개발하였다. 본 연구에서는 tank의 개수, web의 개수 및 종격벽의 위치 변화에 따른 선각 중량 변화를 알아보았으며, 실선 설계에 적용하고자 MARPOL을 만족하는 다양한 tank 배치를 결정하고 선체 전체의 최소 중량 설계를 수행하여 이들 중 선각 중량이 작게 되는 tank 배치를 구하였으며 실적선의 선각 중량과 비교 검토하였다.

• Journal of Nutrition and Health
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• 제30권2호
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• pp.123-131
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• 1997

The influence of (-0-Hydroxycitrate(HCA), shown to be a competitive inhibitor of adenosine 5-triphosphate(ATP) citrate lyase, on food intake and body weight, serum triglyceride and cholosterol level, in vivo rates of fatty acid and cholesterol synthesis, and fat cell number and size was investigated. 3 groups of female, 5 weeks old Sprague Dawley rats, 8 animals each, were ad libitum meal-fed or pair-fed(3 hours from 10 : 00 to 13 : 00) AIN based high glucose diet for a total period of 8 weeks. Providing normolipidemic rats orally with 400mg of HCA formula containing approximately 20mg of HCA 1 hour prior to daily feeding schedule significantly depressed in vivo hepatic rates of fatty acid and cholesterol synthesis in the liver and adipose tissue. Serum triglyceride and cholesterol levels were significantly reduced by HCA. At the end of treatment period, the rats administered with HCA resulted in a significantly reduction in body weight gain. The reduction in weights was attributable to a significant decrease in fat cell size with a smaller extent, but not significant, reduction in fat cell number. Rats receiving HCA demonstrated less food intake than the controls ; however, this decreased caloric intake was not fully responsible for the HCA induced depression of hepatic and adipocytic lipogenesis, since experiment using pair-fed cojntrol rats showed, less magnitude but similar results. Both a anorectic and an antilipogenic properties of HCA seem to be responsible for this weight reduction activity of HCA. The outcome of this study suggest that metabolic regulation may be a feasible approach to the control of obesity and hyperlipidemia.

• 동의신경정신과학회지
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• 제17권2호
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• pp.1-13
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• 2006

Objective : This study examined whether Yangsung program (oriental psychological weight regulation model based on Confucian ideas) is effective on weight loss, self esteem, three factor on eating questionnaires(restraint eating, disinhibition and hunger), distortion of body-image and biochemistry of blood. Method : 23 women were assigned randomly into 2 groups; experimental group(n=10) and control group(n=13). Experimental group had 7 personal sessions consisting of personal Yangsung therapy, meditation, general diet and exercise education. Control group had personal sessions with general diet and exercise education once a week for 6 weeks. All subjects were weighed and evaluated with Rosenberg self esteem scale, distortion of body-image, biochemistry of blood and three factor eating questionnaires at the beginning and end of the program. Result : There is significant difference between two groups in changes of self esteem, disinhibition and hunger(p<0.05). There is no significant difference in weight reduction and BMI between two groups. Conclusion : This study showed a new possibility of unique psychological program for obesity characterized by its philosophical context.

• 산업경영시스템학회지
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• 제45권4호
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• pp.127-133
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• 2022

Many manufacturers applying third party logistics (3PLs) have some challenges to increase their logistics efficiency. This study introduces an effort to estimate the weight of the delivery trucks provided by 3PL providers, which allows the manufacturer to package and load products in trailers in advance to reduce delivery time. The accuracy of the weigh estimation is more important due to the total weight regulation. This study uses not only the data from the company but also many general prediction variables such as weather, oil prices and population of destinations. In addition, operational statistics variables are developed to indicate the availabilities of the trucks in a specific weight category for each 3PL provider. The prediction model using XGBoost regressor and permutation feature importance method provides highly acceptable performance with MAPE of 2.785% and shows the effectiveness of the developed operational statistics variables.

• 동의생리병리학회지
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• 제31권6호
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• pp.362-366
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• 2017

In this study, Banhasasim-tang extracts (BSTE) have an inhibitory effects on cisplatin-induced decrease of body weights in two mouse model. Cisplatin is the most widely used anticancer drug for treatment of various cancer. However, cisplatin treatment to cancer patients leads to many side effects such as nausea, vomiting and body weight decrease. BSTE has been used to decrease digestive disorders in South Korea. We hypothesize that BSTE improve the cisplatin-induced side effects in mouse models. We found that pre- and co-administration of BSTE inhibited decreases of body weights and food intake by cisplatin in mouse models. But BSTE had no synergistic effects for tumor shrinkage by cisplatin in xenograft model. Collectively, our data suggest that BSTE have great potential as a agent for having decrease effects on side effects by cisplatin in cancer patients.