• International Journal of Internet, Broadcasting and Communication
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• v.12 no.2
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• pp.98-112
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• 2020

There is a strong connection between the diet rich in antioxidants and the decreased incidence of inflammatory bowel disease and cancerous diseases. Diets that are rich in anti-oxidants particularly include fruits and vegetables containing the high amounts of vitamin A-E, carotenoids, and minerals. The supercritical heat-treated radish extracts of the research result had an inhibitory effect on the development of aberrant crypt foci (ACF), namely, preneoplastic lesions having a potential to become cancer cells and reduced the number of the aberrant crypt foci (ACF) consisting of four or more aberrant crypts (AC) having high risk to become tumors by about half. The supercritical heat-treated radish extracts can reduce the incidence of preneoplastic lesions having a high risk of developing cancer by about 28 %. DSS-treated mice developed symptoms similar to those of human UC, such as severe bloody diarrhea and weight loss. Supercritical heat-treated radish extracts, as well as sulfasalazine, suppressed colonic length and mucosal inflammatory infiltration. In addition, supercritical heat-treated radish extracts treatment significantly reduced the expression of pro-inflammatory signaling molecules through suppression both mitogen-activated protein kinases (MAPK) and nuclear factor-kappa B (NF-kB) signaling pathways, and prevented the apoptosis of colon. Moreover, supercritical heat-treated radish extracts administration significantly led to the up-regulation of anti-oxidant enzyme including SOD and Catalase.

• KIEAE Journal
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• v.4 no.3
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• pp.113-119
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• 2004

As Building Integrated Photovoltaic(BIPV) system replaces the conventional building finishing materials with PV modules, two function of electricity generation and building envelope can be expected. Therefore BIPV can be a good alternative technology for the 21 century environment-friendly buildings. The objective of this paper is to develope BIPV modules for a commercial buildings of which structure is mainly light-weight, curtain wall system. Two types of module are developed for a opaque part and a transparent part of building envelope. Current technology level and market status of Korea determines the configuration of developed BIPV modules. Architectural considerations for the integration of PV module to building envelope such as building structure, construction type, safety, regulation, maintenance etc. have been carefully reflected from the early stage of BIPV module design. Especially the survey result of current building envelope materials determines the size of unit BIPV modules and a unique cladding method for PV module installation is developed. Trial product of BIPV modules and cladding hardwares are manufactured and sample construction details for a demonstration building are proposed.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2004.11a
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• pp.353-357
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• 2004

The construction competition is more deepened with the enterprise possibility increase which it follows in the regulation relaxation back against the construction market penetration which carries and the instability of market is added an extra weight and it solves the aspect where also the profitability which is caused by with low price bidding decreases. Against a productivity with the overcome plan it is researched plentifully and the far for a productivity improvement, there is so far to construction, the productivity being used with only include meaning, is to a practical affairs and the application ver)r as the level which is feeble is a possibility of doing. It is like that and the research develops the producing district possibility of new steel-frame work and in the actuality which sees the production volume of steel-frame work and a construction accomplishment process effectively and to be right numerical figures it does it plans it controls and manages the place ultimate objective which it puts.

• Proceedings of the KIEE Conference
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• 1999.07f
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• pp.2650-2652
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• 1999

To satisfy the demand for small size, light weight. high density power supply, the switching frequency of DC/DC converters has been increased. The PWM control of the conventional SMPS have a switching frequency that a level of the conducted noise spectra contribute to switching frequency band. So the electronic equipment is not only affected from that but is restricted to internal regulation like CISPR, FCC, and VDE. In this paper, we analyzed Bi-FM. Bi-FM is two fixed switching frequency with a modulation frequency. So emission spectrum of Bi-FM control signal is spreaded and spectral power level is reduced. In this paper, we analyze the spectral analysis of Bi-FM control signal and the spectral comparison between the PWM control and Bi-FM control. And we confirm that reduced the spectrum power level through simulation using Pspice and experiment.

• Proceedings of the KIEE Conference
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• 1999.07f
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• pp.2701-2703
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• 1999

A new mode of parallel operation of a modular 3-phase AC-DC Flyback converter for high power factor correction along with tight regulation is presented in this thesis. The converter offers input/output transformer isolation for safety, a unity input power factor for minimum reactive power, high efficiency and high power density for minimum weight and volume. Compared with previously developed 3-phase two-stage power converter, the advantage of the proposed converter does not require expensive high voltage and high current devices that are normally needed in popular boost type 3-phase converter. In this paper, a detailed small signal analysis of the modular 3-phase AC-DC flyback converter is provided for control purposes and also experimental results are included to confirm the validity of the analysis.

• BMB Reports
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• v.49 no.7
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• pp.370-375
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• 2016

Ras oncoproteins are small molecular weight GTPases known for their involvement in oncogenesis, which operate in a complex signaling network with multiple effectors. Approximately 25% of human tumors possess mutations in a member of this family. The Raf1/MEK/Erk1/2 pathway is one of the most intensively studied signaling mechanisms. Different levels of regulation account for the inactivation of MAP kinases by MAPK phosphatases in a cell type- and stimuli-dependent manner. In the present study, using three inducible Ras-expressing NIH/3T3 cell lines, we demonstrated that MKP3 upregulation requires the activation of the Erk1/2 pathway, which correlates with the shutdown of this pathway. We also demonstrated, by applying pharmacological inhibitors and effector mutants of Ras, that induction of MKP3 at the protein level is positively regulated by the oncogenic Ras/Raf/MEK/Erk1/2 signaling pathway.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.7 no.3
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• pp.213-221
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• 1987

To use fly ash as an additive for concrete, authors collected 15 kinds of domestic fly ashes and tested the chemical compositions and physical properties of the fly ashes. Fluidity of the fly ash paste was also investigated. The result shows that the chemical compositions of the fly ashes were in the range of regulation of Korean Industrial Standards except ignition loss and the following relationships in fly ash were studied; specific surface and residue in standard sieve, specific surface and unit weight, residue in standard sieve and ignition loss. For the given flow properties, fly ash paste required higher water-binder ratio than cement paste.

• Biomolecules & Therapeutics
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• v.22 no.4
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• pp.341-346
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• 2014

Paeonol is a major phenolic micromolecular component of Moutan cortex Radicis, a traditional Chinese Medicine. It has shown antitumor effects in previous studies; however, the underlying mechanisms remain unknown. This study investigated the mechanism by giving treatments of placebo, cyclophosphamide, paeonol of 150 and 300 mg/kg to 4 groups of mice bearing EMT6 breast cancer. Apoptosis in tumor cells were confirmed by morphology analysis, including hematoxylin, eosin staining and TUNEL staining. The results showed that the weight of EMT6 breast tumor was significantly reduced in the groups treated with both 150 and 300 mg/kg of paeonol. Immunohistochemical and Western blot results showed that the expression of Bcl-2 was down-regulated while the expression of Bax, caspase 8 and caspase 3 was up-regulated respectively. These results suggest that paeonol exhibits antitumor effects and the mechanism of the inhibition is via induction of apoptosis, regulation of Bcl-2 and Bax expression, and activation of caspase 8 and caspase 3.

• Journal of the Society of Naval Architects of Korea
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• v.51 no.3
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• pp.212-219
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• 2014

As subsea production has been revived up, the demand of subsea equipment has also been increased. Among the equipment, subsea tree plays a major role in safety. The tubing hanger is one of the most important components in subsea tree. In this study structural reliability analysis on dual bore tubing hanger of subsea tree is performed. The target reliability which is introduced in ISO regulation is used for judging whether tubing hanger is safe or not. The considered loads are working pressure, working temperature and suspended tubing weight. Thermal-stress analysis on tubing hanger is performed and kriging model is created based on the results of FEM analysis. According to von Mises criterion, limit state equation can be estimated. Reliability analysis is performed by using level 2 method and the result is verified by that of Monte Carlo Simulation. For finding most probable failure point, enhanced HL-RF method is adopted. Because the reliability of model doesn't reach target reliability, an improvement measure should be considered. Thus, it is suggested to change the material of tubing hanger main body to AISI 4140.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.19 no.6
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• pp.724-730
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• 2010

A load cell is a converter that generates voltage signals when a certain force is effected in a given direction. An essential measurement device for electronic scales that indicate weight by numbers. These load cells are being applied in various areas such as daily life, distribution, laboratory and industrial. Recently the study to manufacture load cells in a more simple method while increasing performance is being persisted. In this study based on the comparison of load cells manufactured through single surface processing using strain gauges. Those manufactured through dual surface processing using strain gauges. Ultimately persist a more simple method of load cell manufacturing while increasing its performance. The elements that were compared were linearity, hysteresis, creep and eccentricity which are short tenn performance factors. The conclusion was that single surface processing showed almost identical data as that of dual surface processing, and the load cell error rate(0.005%) also excess regulation. The manufacturing time was shortened while mass-production was possible. Which indicates a development in the weighing industry.