• 대한의용생체공학회:의공학회지
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• 제38권3호
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• pp.123-128
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• 2017

Background and aims: The KCNQ1 S140G mutation involved in $I_{ks}$ channel is a typical gene mutation affecting atrial fibrillation. However, despite the possibility that the S140G gene mutation may affect not only atrial but also ventricular action potential shape and ventricular responses, there is a lack of research on the relationship between this mutation and ventricular fibrillation. Therefore, in this study, we analyzed the correlation and the influence of the KCNQ1 S140G mutant gene on ventricular fibrillation through computer simulation studies. Method: This study simulated a 3-dimensional ventricular model of the wild type(WT) and the S140G mutant conditions. It was performed by dividing into normal sinus rhythm simulation and reentrant wave propagation simulation. For the sinus rhythm, a ventricular model with Purkinje fiber was used. For the reentrant propagation simulation, a ventricular model was used to confirm the occurrence of spiral wave using S1-S2 protocol. Results: The result showed that 41% shortening of action potential duration(APD) was observed due to augmented $I_{ks}$ current in S140G mutation group. The shortened APD contributed to reduce wavelength 39% in sinus rhythm simulation. The shortened wavelength in cardiac tissue allowed re-entrant circuits to form and increased the probability of sustaining ventricular fibrillation, while ventricular electrical propagation with normal wavelength(20.8 cm in wild type) are unlikely to initiate re-entry. Conclusion: In conclusion, KCNQ1 S140G mutation can reduce the threshold of the re-entrant wave substrate in ventricular cells, increasing the spatial vulnerability of tissue and the sensitivity of the fibrillation. That is, S140G mutation can induce ventricular fibrillation easily. It means that S140G mutant can increase the risk of arrhythmias such as cardiac arrest due to heart failure.

• 대한족부족관절학회지
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• 제10권2호
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• pp.163-167
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• 2006

Purpose: To evaluate the results of extracorporeal shock wave therapy (ESWT) for patients with chronic proximal plantar fascitis. Materials and Methods: Between April 2005 and April 2006, 35 cases (24 patients) who were followed more than 6 months were evaluated. By $EvoTron^{(R)}$, 2 sessions of ESWT (Group 1: 1200 and Group 2: 1500 shock waves / session of $0.12\;mJ/mm^2$) were performed at 2 weeks interval. The mean age was 40.0 (range, 15-59) years. 13 patients were male and 11 patients were female. Visual analogue scale (VAS) on daily activity and a 100-point scoring system including 70 points for pain and 30 points for function were used. The clinical outcomes were rated as follows: excellent, no pain on daily activity; good, less than 50% of previous VAS; fair, 50-75% of previous VAS; or poor, more than 75% of previous VAS. Excellent and good were graded as satisfactory results. We compare clinical results between groups and evaluate the relationships between clinical results and duration of symptom, fascial thickening and previous steroid injection were evaluated. Results: Overall satisfactory rate were 71.4%. There was no significant difference of clinical results between groups. And there were no significant difference between clinical results and duration of symtom, preoperative fascial thickening and previous steroid injection. Conclusions: ESWT for recalcitrant chronic proximal plantar fascitis is useful treatment method with high patient satisfaction and pain relief, but more long-term study must be needed.

• 한국지구과학회지
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• 제26권3호
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• pp.240-252
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• 2005

한반도 주변 해역의 5개 지점(덕적도, 칠발도, 거문도, 거제도, 동해 정점)에서 관측된 기상청의 해양 기상 관측 부이 자료를 이용하여 각 해역에서 바람과 파도의 관계를 분석하였다. 전반적으로는 서해 정점에서는 파도가 바람의 영향을 가장 많이 받고 남해 정점에서는 파도가 바람의 영향을 가장 적게 받으며 동해 정점에서는 그 중간이며 각 정점별 특징은 다음과 같다. 칠발도에서는 풍속이 강한 겨울철의 주 풍향인 북서방향으로 바다가 트여있고 얕은 수심에 의한 여울효과로 가장 높은 파고가 발달하며 풍향과 파향이 다른 정점에 비해서 가장 잘 일치한다. 이에 비해 덕적도는 북서방향이 황해도에 의해 막혀 있기 때문에 취송거리가 제한되어 겨울철에 충분히 발달한 파도가 생기지 않는다. 이러한 취송거리의 제한은 남해 정점에서 더 크다. 북풍이 우세한 남해의 두 정점에서는 북쪽의 육지 때문에 파도의 발달이 제한되어 바람이 강해도 파고는 거의 높아지지 않는다. 남해 정점에서는 어느 방향에서 바람이 불든지 모든 파향의 파가 고르게 유입되며 그 중 우세한 파향은 항상 동중국해에서 유입되는 방향이다. 그 방향은 거문도와 거제도에서 각각 남쪽 방향과 남서 방향이며 이 방향으로는 바람이 약할 때도 파도가 유입된다. 동해 정점에서는 수심이 깊어 파도가 크게 발달하지만 풍향과 파향이 일치하지 않는 경우가 많아 파고의 발달이 칠발도에서 보다는 낮다. 이와 같이 풍속과 더불어 풍향이 파랑발달에 중요한 이유는 풍향에 의해 취송거리가 결정되기 때문이다. 덕적도와 칠발도에서 풍향이 변하지 않고 오래 지속되는 경우를 보면 파향이 풍향과 일치하며 파고는 최대풍속 후에 최대파고가 나타나는 반응시간이 길수록 커지는 것을 볼 수 있다. 그러나 풍향과 파향이 일치하지 않는 동해 정점의 경우에서는 풍속이 크고 반응시간이 길어도 파고가 서해 정점에서와 같이 많이 높아지지는 않는다. 이상의 결과는 풍속이 클수록, 취송거리가 길수록, 지속시간이 길수록 파고가 크게 발달하는 일반적인 경향과 더불어 각 정점별로는 육지와 바다의 방향, 해저지형, 주변해역의 규모 등의 환경조건에 의해 바람에 의한 파도의 발달율이 달라지는 것을 보여준다.

• Journal of Welding and Joining
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• 제14권5호
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• pp.59-68
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• 1996

This study was aimed to characterize the laser cutting process for the cold rolled stainless steel sheet. The principal process parameters of the cutting process were applied to both the continuous wave form and the pulsed wave form for the laser output mode. The laser-oxygen cutting process and the laser-nitrogen cutting process were also considered to characterize the quality and efficiency of the cutting process. The laser-oxygen cutting process revealed the better productivity than the laser-nitrogen cutting process, since the laser energy and the exothermic oxidation energy exerted on the laser-oxygen cutting process simultaneously during the entire cutting process. However, the straightness of the cutting section, which was considered as the most important factors, was inferior to that of the laser-nitrogen cutting process due to the formation of chromum oxide on the cutting surface. Frequency and duration of the pulsed wave form act as the main factors for the better quality, When the frequency increased from 100 Hz to 200 Hz and the duty increased from 20% to 40%, the quality factors such as the height of dross and the surface roughness were improved remarkably. The increase in the frequency from 200 Hz to 300 Hz, on the other hand, revealed the less effective in the cutting quality.

• 한국해안해양공학회지
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• 제11권3호
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• pp.141-148
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• 1999

圓形 파일에 작용하는 卷波性 碎波力은 쇄파제원과 동일한 正弦波를를 대상으로 한 모리슨식의 계산치보다 그 크기는 월등 크나 보통 백분의 수초 이내의 매우 짧은 시간 동안 작용한다. 따라서, 碎波力을 받는 파일의 설계에서 파일의 變位를 정확히 결정하기 위해서는 쇄파력 작용에 의한 動的擧動을 해석하여야 한다. 이를 위해서는 파일 延長上 쇄파력의 시게열에 대한 事前정보가 필요하며, 이는 파일 주변의 碎波壓 시계열로부터 간접적으로 추정할 수 있다. 본 연구에서는 卷波性 碎波의 작용에 따른 쇄파압의 특성을 정량적으로 고찰하기 위하여 實海域에 설치되어 잇는 원형파일에 波壓計를 부착하여 쇄파압을 관측하고 그 결과를 제시하였다.

• 한국해양환경ㆍ에너지학회지
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• 제18권4호
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• pp.282-290
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• 2015

부이의 수직운동으로부터 파랑에너지를 추출하는 파력발전기의 추출효율을 극대화하기 위하여 Sheng et al.(2015)이 제안한 래칭 제어기법을 적용하였다. 래칭 제어기법은 부이를 구속하는 래칭 시간을 조절하여 추출효율을 높이는 위상제어 방법이다. 래칭 제어기법을 규칙파중 수직운동하는 부이에 적용한 결과, 공진조건을 만족하지 않았음에도 불구하고 부이의 운동속도와 추출파워는 크게 증가하였다. 부이의 수직운동으로부터 파랑에너지를 흡수하는 파력발전기에 이러한 래칭 제어기법을 도입하면 추출파워의 증가와 더불어 부이의 흘수와 PTO감쇠력을 줄일 수 있어 제작비용을 크게 낮출 수 있다.

• Journal of Astronomy and Space Sciences
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• 제37권1호
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• pp.19-27
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• 2020

Pc1 pulsations are important to consider for the interpretation of wave-particle interactions in the Earth's magnetosphere. In fact, the wave properties of these pulsations change dynamically when they propagate from the source region in the space to the ground. A detailed study of the wave features can help understanding their time evolution mechanisms. In this study, we statistically analyzed Pc1 pulsations observed by a Bohyunsan (BOH) magneto-impedance (MI) sensor located in Korea (L = 1.3) for ~one solar cycle (November 2009-August 2018). In particular, we investigated the temporal occurrence ratio of Pc1 pulsations (considering seasonal, diurnal, and annual variations in the solar cycle), their wave properties (e.g., duration, peak frequency, and bandwidth), and their relationship with geomagnetic activities by considering the Kp and Dst indices in correspondence of the Pc1 pulsation events. We found that the Pc1 waves frequently occurred in March in the dawn (1-3 magnetic local time (MLT)) sector, during the declining phase of the solar cycle. They generally continued for 2-5 minutes, reaching a peak frequency of ~0.9 Hz. Finally, most of the pulsations have strong dependence on the geomagnetic storm and observed during the early recovery phase of the geomagnetic storm.

• 한국마린엔지니어링학회:학술대회논문집
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• 한국마린엔지니어링학회 2005년도 후기학술대회논문집
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• pp.37-38
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• 2005

Although the law of classical fourier heat conduction predicts the heat conduction phenomena occurred in most engineering fields with a good accuracy, it is also well-known that the conventional fourier law of a heat conduction has an application limit when the heating and cooling are periodic for a short duration or when the heat conduction is analyzed in the extremely low temperature region. This application limit of classical fourier law results from the fact that it assumed the infinite speed of a heat wave. In this study, we investigated the feasibility of whether the molecular dynamics could be used to calculate the speed of a heat wave through a solid. The calculated sound velocity showed a good agrement with the theoretical prediction qualitatively. From the calculated results, we confirmed that the same methodology can be applied the evaluation of the speed of a heat wave.

• 한국해양공학회지
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• 제11권4호
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• pp.111-121
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• 1997

The spectral energy balance model is composed and the nonlinear interaction is approximated by the discrete interaction parameterization as in WAM model. The numerical results of durational limited growth test agree very well with those of the exact model, EXACT-NL. The response of a wave spectrum to a change in wind direction is investigated numerically for a sequence of direction changes 30$^{\circ}$ , 45$^{\circ}$ , 60$^{\circ}$ , 90$^{\circ}$ . The high frequency components relax more repidly to the new wind direction than the low frequency components and the relaxation process also depends on the wave age. For wind direction changes less than 60$^{\circ}$ , the coupling by nonlinear interaction is so strong that the secondary peak in input source distribution is counteracted by the negative lobe of the nonlinear interaction. For wind direction changes grater than 60$^{\circ}$ , a second independent wind-sea spectrum is generated in the new wind direction, while the old spectrum gradually decays as swell.

• 대한후두음성언어의학회지
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• 제7권1호
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• pp.50-55
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• 1996

Acoustic analysis study was performed on 20 normal subjects by speaking nonsense syllables composed of Korean bilabial stops$(/P, P^{\star}, P^{h}/)$ and their preceding and/or following vowel /a/ (that is, $[pa, p^{\star}a, p^{h}a, apa, ap^{\star}a, ap^{h}a]$) with an ultraminiature pressure, sensor. in their mouths. Speech materials were phonated twice, once with a moderate voice, another time with a loud voice. The acoustic signal and intraoral pressure were recorded simultaneously on computer. By these procedures, we were to measure the intraoral pressure, closure duration and VOT of Korean bilabial stops, and to compare the values one another according to the intensity of phonation and the position of the target consonants. Intraoral pressure was measured by the peak intraoral pressure value of Its wave closure duration by the time interval between the onset of intraoral pressure build-up and the burst meaning the release of closure ; Voice onset time(VOT) on by the time interval between the burst and the onset or glottal vibration. Heavily aspirated bilabial stop consonant /$p^h$/ showed the highest intraoral pressure value, unaspirated /$p^{\star}$/, the second, slightly aspirated /P/, the lowest. The syllable initial bilabial stops showed higher intraoral pressure than word initial stops, and the value of loudly phonated consonants were higher than moderate consonants. The longest closure duration period was that of /$p^{\star}$/ and the shortest, /P/, and the duration was longer in word initial position and in the moderate voice. In VOT, the order of the longest to shortest was $/{p^h}/, /p/, /{p^\star}/$, and the value was shorer when the consonant was in intervocalic position and when it was phonated with a loud voice.