• Journal of Biomedical Engineering Research
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• v.38 no.3
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• pp.123-128
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• 2017

Background and aims: The KCNQ1 S140G mutation involved in $I_{ks}$ channel is a typical gene mutation affecting atrial fibrillation. However, despite the possibility that the S140G gene mutation may affect not only atrial but also ventricular action potential shape and ventricular responses, there is a lack of research on the relationship between this mutation and ventricular fibrillation. Therefore, in this study, we analyzed the correlation and the influence of the KCNQ1 S140G mutant gene on ventricular fibrillation through computer simulation studies. Method: This study simulated a 3-dimensional ventricular model of the wild type(WT) and the S140G mutant conditions. It was performed by dividing into normal sinus rhythm simulation and reentrant wave propagation simulation. For the sinus rhythm, a ventricular model with Purkinje fiber was used. For the reentrant propagation simulation, a ventricular model was used to confirm the occurrence of spiral wave using S1-S2 protocol. Results: The result showed that 41% shortening of action potential duration(APD) was observed due to augmented $I_{ks}$ current in S140G mutation group. The shortened APD contributed to reduce wavelength 39% in sinus rhythm simulation. The shortened wavelength in cardiac tissue allowed re-entrant circuits to form and increased the probability of sustaining ventricular fibrillation, while ventricular electrical propagation with normal wavelength(20.8 cm in wild type) are unlikely to initiate re-entry. Conclusion: In conclusion, KCNQ1 S140G mutation can reduce the threshold of the re-entrant wave substrate in ventricular cells, increasing the spatial vulnerability of tissue and the sensitivity of the fibrillation. That is, S140G mutation can induce ventricular fibrillation easily. It means that S140G mutant can increase the risk of arrhythmias such as cardiac arrest due to heart failure.

• Journal of Korean Foot and Ankle Society
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• v.10 no.2
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• pp.163-167
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• 2006

Purpose: To evaluate the results of extracorporeal shock wave therapy (ESWT) for patients with chronic proximal plantar fascitis. Materials and Methods: Between April 2005 and April 2006, 35 cases (24 patients) who were followed more than 6 months were evaluated. By $EvoTron^{(R)}$, 2 sessions of ESWT (Group 1: 1200 and Group 2: 1500 shock waves / session of $0.12\;mJ/mm^2$) were performed at 2 weeks interval. The mean age was 40.0 (range, 15-59) years. 13 patients were male and 11 patients were female. Visual analogue scale (VAS) on daily activity and a 100-point scoring system including 70 points for pain and 30 points for function were used. The clinical outcomes were rated as follows: excellent, no pain on daily activity; good, less than 50% of previous VAS; fair, 50-75% of previous VAS; or poor, more than 75% of previous VAS. Excellent and good were graded as satisfactory results. We compare clinical results between groups and evaluate the relationships between clinical results and duration of symptom, fascial thickening and previous steroid injection were evaluated. Results: Overall satisfactory rate were 71.4%. There was no significant difference of clinical results between groups. And there were no significant difference between clinical results and duration of symtom, preoperative fascial thickening and previous steroid injection. Conclusions: ESWT for recalcitrant chronic proximal plantar fascitis is useful treatment method with high patient satisfaction and pain relief, but more long-term study must be needed.

• Journal of the Korean earth science society
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• v.26 no.3
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• pp.240-252
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• 2005

The relationships between wave and wind around the Korean Peninsula have been analyzed with the data from the buoys moored at five stations (Dugjug-do, Chilbal-do, Geomoon -do, Geoje-do, Donghae) by Korea Meteorological Administration. Generally, the relationship between wave and wind is the highest at the stations in the West Sea and the lowest at the stations in the South Sea, and the middle at the station in the East Sea. The characteristics shown at each station are as follows. Highest wave is developed at Chilbal-do with strong northwesterly wind in winter because the sea is opened in the wind direction and wave is amplified by shoaling effect. At Chilbal-do, wave directions coincide with wind directions relatively well. On the other hand, waves are not fully developed at Dugjug-do in winter due to limited fetch since the sea is blocked by Hwanghae-do in the northwest direction. The limitation in fetch is more serious at the stations in the South Sea. In the South Sea, the direction of dominant northerly wind is blocked by land so that wave heights are small even with very strong northerly wind. In the South Sea, whatever wind direction is, waves dominantly come in the direction from the East China Sea, which are from the south at Geomoon-do and the southwest at Geoje-do. At these directions, waves are coming even with weak wind. At the station in the East Sea, waves are highly developed due to vast area, but not so high as in Chilbal-do because wind and wave directions do not coincide in many cases. As shown, wind direction is important in the wave development as well as wind speed. The reason is that the fetch is determined by wind direction. In the case of long-lasted wind with fixed direction at Chilbal-do and Dugjug-do, wave directions are well coincident with wind directions and wave heights increase with response time, which is the duration between the highest wind and wave. However, in the case of disagreement between wind and wave directions at the station in the East Sea, wave heights do not increase as highly as at Chilbal-do and Dugjug-do in spite of strong wind and longer response time. The results show us that waves are highly developed with strong wind, long fetch, and long duration, and also show that wave development ratios are different at different stations due to environmental factors such as the direction towards sea or land, bottom topography, and the scales of adjacent seas.

• Journal of Welding and Joining
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• v.14 no.5
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• pp.59-68
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• 1996

This study was aimed to characterize the laser cutting process for the cold rolled stainless steel sheet. The principal process parameters of the cutting process were applied to both the continuous wave form and the pulsed wave form for the laser output mode. The laser-oxygen cutting process and the laser-nitrogen cutting process were also considered to characterize the quality and efficiency of the cutting process. The laser-oxygen cutting process revealed the better productivity than the laser-nitrogen cutting process, since the laser energy and the exothermic oxidation energy exerted on the laser-oxygen cutting process simultaneously during the entire cutting process. However, the straightness of the cutting section, which was considered as the most important factors, was inferior to that of the laser-nitrogen cutting process due to the formation of chromum oxide on the cutting surface. Frequency and duration of the pulsed wave form act as the main factors for the better quality, When the frequency increased from 100 Hz to 200 Hz and the duty increased from 20% to 40%, the quality factors such as the height of dross and the surface roughness were improved remarkably. The increase in the frequency from 200 Hz to 300 Hz, on the other hand, revealed the less effective in the cutting quality.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.11 no.3
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• pp.141-148
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• 1999

The magnitude of breaking wave forces given by plunging breakers incident on a pile structure is much greater than the forces calculated by Morison's formula, but those forces may act on pile for very short duration in the range of a few multiples of 0.01 second. Hence, a dynamic analysis for the impact forces of breaking waves may be necessary for the accurate determination of pile displacements in the first stage of design. The time series of the impact force along the pile length is thus required, which may be estimated from the pressure distribution. In the present study, breaking wave pressures are measured for a vertical pile at real field which is easily subjected to plunging breakers in stormy weather conditions. The measured data are analyzed and compared with other results to quantify the characteristics of breaking wave pressures in real fields.

• Journal of the Korean Society for Marine Environment & Energy
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• v.18 no.4
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• pp.282-290
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• 2015

In this study, a latching control technology, proposed by Sheng et al.(2015), was applied in order to maximize the extraction efficiency of WEC (Wave Energy Converter), which is the heaving buoy coupled with linear electric generator. The latching control is the phase-control technique for improving the wave energy conversion with appropriate latching duration of keeping the buoy fixed. From the time-domain analysis in regular waves, the latching control technology can significantly improve the heave velocity and extracted power, even though the resonance condition is not satisfied. By using the latching control technology, the draft of buoy as well as the required PTO damping force can be significantly reduced along with increased extracted power, which is a big advantage in manufacturing the WEC.

• Journal of Astronomy and Space Sciences
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• v.37 no.1
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• pp.19-27
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• 2020

Pc1 pulsations are important to consider for the interpretation of wave-particle interactions in the Earth's magnetosphere. In fact, the wave properties of these pulsations change dynamically when they propagate from the source region in the space to the ground. A detailed study of the wave features can help understanding their time evolution mechanisms. In this study, we statistically analyzed Pc1 pulsations observed by a Bohyunsan (BOH) magneto-impedance (MI) sensor located in Korea (L = 1.3) for ~one solar cycle (November 2009-August 2018). In particular, we investigated the temporal occurrence ratio of Pc1 pulsations (considering seasonal, diurnal, and annual variations in the solar cycle), their wave properties (e.g., duration, peak frequency, and bandwidth), and their relationship with geomagnetic activities by considering the Kp and Dst indices in correspondence of the Pc1 pulsation events. We found that the Pc1 waves frequently occurred in March in the dawn (1-3 magnetic local time (MLT)) sector, during the declining phase of the solar cycle. They generally continued for 2-5 minutes, reaching a peak frequency of ~0.9 Hz. Finally, most of the pulsations have strong dependence on the geomagnetic storm and observed during the early recovery phase of the geomagnetic storm.

• Proceedings of the Korean Society of Marine Engineers Conference
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• 2005.11a
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• pp.37-38
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• 2005

Although the law of classical fourier heat conduction predicts the heat conduction phenomena occurred in most engineering fields with a good accuracy, it is also well-known that the conventional fourier law of a heat conduction has an application limit when the heating and cooling are periodic for a short duration or when the heat conduction is analyzed in the extremely low temperature region. This application limit of classical fourier law results from the fact that it assumed the infinite speed of a heat wave. In this study, we investigated the feasibility of whether the molecular dynamics could be used to calculate the speed of a heat wave through a solid. The calculated sound velocity showed a good agrement with the theoretical prediction qualitatively. From the calculated results, we confirmed that the same methodology can be applied the evaluation of the speed of a heat wave.

• Journal of Ocean Engineering and Technology
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• v.11 no.4
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• pp.111-121
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• 1997

The spectral energy balance model is composed and the nonlinear interaction is approximated by the discrete interaction parameterization as in WAM model. The numerical results of durational limited growth test agree very well with those of the exact model, EXACT-NL. The response of a wave spectrum to a change in wind direction is investigated numerically for a sequence of direction changes 30$^{\circ}$ , 45$^{\circ}$ , 60$^{\circ}$ , 90$^{\circ}$ . The high frequency components relax more repidly to the new wind direction than the low frequency components and the relaxation process also depends on the wave age. For wind direction changes less than 60$^{\circ}$ , the coupling by nonlinear interaction is so strong that the secondary peak in input source distribution is counteracted by the negative lobe of the nonlinear interaction. For wind direction changes grater than 60$^{\circ}$ , a second independent wind-sea spectrum is generated in the new wind direction, while the old spectrum gradually decays as swell.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.7 no.1
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• pp.50-55
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• 1996

Acoustic analysis study was performed on 20 normal subjects by speaking nonsense syllables composed of Korean bilabial stops$(/P, P^{\star}, P^{h}/)$ and their preceding and/or following vowel /a/ (that is, $[pa, p^{\star}a, p^{h}a, apa, ap^{\star}a, ap^{h}a]$) with an ultraminiature pressure, sensor. in their mouths. Speech materials were phonated twice, once with a moderate voice, another time with a loud voice. The acoustic signal and intraoral pressure were recorded simultaneously on computer. By these procedures, we were to measure the intraoral pressure, closure duration and VOT of Korean bilabial stops, and to compare the values one another according to the intensity of phonation and the position of the target consonants. Intraoral pressure was measured by the peak intraoral pressure value of Its wave closure duration by the time interval between the onset of intraoral pressure build-up and the burst meaning the release of closure ; Voice onset time(VOT) on by the time interval between the burst and the onset or glottal vibration. Heavily aspirated bilabial stop consonant /$p^h$/ showed the highest intraoral pressure value, unaspirated /$p^{\star}$/, the second, slightly aspirated /P/, the lowest. The syllable initial bilabial stops showed higher intraoral pressure than word initial stops, and the value of loudly phonated consonants were higher than moderate consonants. The longest closure duration period was that of /$p^{\star}$/ and the shortest, /P/, and the duration was longer in word initial position and in the moderate voice. In VOT, the order of the longest to shortest was $/{p^h}/, /p/, /{p^\star}/$, and the value was shorer when the consonant was in intervocalic position and when it was phonated with a loud voice.