• Nutrition Research and Practice
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• v.12 no.2
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• pp.101-109
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• 2018

BACKGROUD/OBJECTIVES: The objective of this study was to investigate the effects of vitamin C on inflammation, tumor development, and dysbiosis of intestinal microbiota in an azoxymethane (AOM)/dextran sulfate sodium (DSS)-induced inflammation-associated early colon cancer mouse model. MATERIALS/METHODS: Male BALB/c mice were injected intraperitoneally with AOM [10 mg/kg body weight (b.w)] and given two 7-d cycles of 2% DSS drinking water with a 14 d inter-cycle interval. Vitamin C (60 mg/kg b.w. and 120 mg/kg b.w.) was supplemented by gavage for 5 weeks starting 2 d after the AOM injection. RESULTS: The vitamin C treatment suppressed inflammatory morbidity, as reflected by disease activity index (DAI) in recovery phase and inhibited shortening of the colon, and reduced histological damage. In addition, vitamin C supplementation suppressed mRNA levels of pro-inflammatory mediators and cytokines, including cyclooxygenase-2, microsomal prostaglandin E synthase-2, tumor necrosis $factor-{\alpha}$, Interleukin $(IL)-1{\beta}$, and IL-6, and reduced expression of the proliferation marker, proliferating cell nuclear antigen, compared to observations of AOM/DSS animals. Although the microbial composition did not differ significantly between the groups, administration of vitamin C improved the level of inflammation-related Lactococcus and JQ084893 to control levels. CONCLUSION: Vitamin C treatment provided moderate suppression of inflammation, proliferation, and certain inflammation-related dysbiosis in a murine model of colitis associated-early colon cancer. These findings support that vitamin C supplementation can benefit colonic health. Long-term clinical studies with various doses of vitamin C are warranted.

• Journal of Korean Society of Water and Wastewater
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• v.23 no.6
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• pp.719-726
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• 2009

One of the alternative runoff management measures is on-site runoff mitigation, such as rainwater retention tank and infiltration facilities especially the latter that is possible to manage simultaneously runoff quality and quantity as a perspective of water-cycle. This study was conducted to develop a particle separator, inclined-pipe settling system, that could improve particle removal efficiency of road runoff as a pre-treatment device of stormwater infiltration. Solid particles larger than $100{\mu}m$ are separated by simple sedimentation; however, the significant amount of pollutants with a diameter less than $100{\mu}m$ remain in suspension. Without any treatment in that case of the runoff into infiltrate, groundwater would be deteriorated and also infiltration rate would be decreased by clogging. Therefore, we suggest optimal design parameters (inclined angle, pipe length, and surface loading rate) of inclined-pipe settling system which can be designed to effectively remove particles diameter smaller then $70{\mu}m$. Thus, the results showed TSS removal efficiency more than 80% with a particle diameter between $20{\mu}m$ and $70{\mu}m$, 100% above particle diameter $70{\mu}m$ for the inflow rate $0.018 m^3/m^2{\cdot}hr$ with pipe inclined at angle $15^{\circ}$.

• Journal of Korea Water Resources Association
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• v.37 no.4
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• pp.305-314
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• 2004

Climate change mainly due to the increase of green house gases cause different patterns of water cycle within the basin. However, it is common that current planning and management practices do not consider the effect of the climate change. So, this study evaluated the effect of climate change on the water circulation within the watershed. This study used several GCM simulations for the double $CO_2$condition for the generation of temperature and rainfall series using the Markov chain. Daily runoff series for 100 years were generated using a rainfall-runoff model. As results. annual temperature increase by ＋3.2 ∼＋4.6$^{\circ}C$, annual precipitation change －7 ∼ ＋8 %, annual runoff change －14 ∼ ＋7 %, and potential evapotranspiration amount change ＋3 ∼＋4 % for the change of 1 $^{\circ}C$ are found to be expected depending on GCM simulations. Even though the simulation results are very dependent on the GCM predictions considered, overall variability of runoff is expected to become higher than the current state.

• Asian-Australasian Journal of Animal Sciences
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• v.22 no.11
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• pp.1540-1546
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• 2009

One hundred and forty-four piglets with an average birth weight of 1,672${\pm}$13.4 g were used to evaluate different feeding strategies for piglets reared from birth on a dummy sow. A 3${\times}$2 factorial experiment compared three nursing frequencies (1, 3 or 6 h intervals) and two feeding regimes (milk only, or milk combined with access to creep feed and water). The piglets which were nursed at one hour intervals had the lightest body weights at all days, and the poorest combined milk and creep feed dry matter conversion efficiency to piglet body weight gain in the second week. Piglets which were nursed at 3 h intervals had the heaviest body weight at day 15 and 22, but those nursed at 6 h intervals achieved similar body weight by days 29 (milk withdrawal) and 36. Piglets offered creep feed were observed to wean themselves before cessation of milk availability, and the timing of this self-weaning depended on the nursing frequency. The piglets nursed at one hour intervals weaned themselves between day 22 and day 29, those nursed at 3 h intervals weaned themselves between day 15 and day 22, whilst those nursed at 6 h intervals weaned themselves between day 8 and day 15. The piglets which were nursed at 6 h intervals had the highest total dry matter intake in weeks 3 and 4 when fed with milk, creep feed and water but not when fed milk only. They consequently had the poorest dry matter conversion efficiency in the fourth week and overall when fed with milk, creep feed and water, but not when fed milk only. It is concluded that the optimal management routine under these conditions is a 3 h nursing cycle with provision of supplementary creep feed and water.

• Journal of the Korea Institute of Building Construction
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• v.6 no.1 s.19
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• pp.87-91
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• 2006

Since water leakage and cracks are not the source of serious problems such as long-term lowering of performance and durability of a stricture, including damages to operating facilities of a structure, damages to internal finishing materials, exhibition, and goods, and pollution of residential environment, they might have led to development of positive coping skills; however, an instant loss of lives or property due to earthquake, explosion, typhoon, or a fire was indeed neglected. In these days, repair materials for leakage cannot help but being taken in temporary way without any noticeable countermeasure. This kind of repair is socially criticized many times that is defective construction even if this costs a lot. It was not arrange the standard for construction methods of sealer of injection type for leakage maintenance, even it has been used various type of construction methods for leakage part. In conclusion, we suggest that the construction methods of sealer of injection type for leakage maintenance for leakage to establish the leakage repairing technology as increase of structure demand. Therefore, it would be possible to provide a stage-by-stage solution by developing systematic research activities among the industry, schools, and research institutes to spread maintenance management techniques globally through technical solution to water leakage and cracks, acquisition of structural safety with prolonged durability for life cycle, reduction of water leakage repair expense s, and so on.

• Fisheries and Aquatic Sciences
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• v.20 no.8
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• pp.16.1-16.8
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• 2017

The exportation of cultured olive flounder (Paralichthys olivaceus) in Korea has been recently decreasing due to the infections with a myxozoan parasite Kudoa septempunctata, and there is a strong demand for strict food safety management because the food poisoning associated with consumption of raw olive flounder harbouring K. septempunctata has been frequently reported in Japan. The life cycle and infection dynamics of K. septempunctata in aquatic environment are currently unknown, which hamper establishment of effective control methods. We investigated sea water and marine invertebrates collected from olive flounder farms for detecting K. septempunctata by DNA-based analysis, to elucidate infection dynamics of K. septempunctata in aquaculture farms. In addition, live marine polychaetes were collected and maintained in well plates to find any possible actinosporean state of K. septempunctata. The level of K. septempunctata DNA in rearing water fluctuated during the sampling period but the DNA was not detected in summer (June-July in farm A and August in farm B). K. septempunctata DNA was also detected in the polychaetes Naineris laevigata intestinal samples, showing decreased pattern of 40 to 0%. No actinosporean stage of K. septempunctata was observed in the polychaetes by microscopy. The absence of K. septempunctata DNA in rearing water of fish farm and the polychaetes N. laevigata intestinal samples during late spring and early summer indicate that the infection may not occur during this period. N. laevigata was suspected as the possible alternate invertebrate host of K. septempunctata, but the actinosporean stage was not found by well plate method and further studies will be necessary. This research provides important baseline information for understanding the infection dynamics of K. septempunctata in olive flounder farms and further establishment of control strategies.

• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.500-500
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• 2022

「물환경보전법」은 2007년의 「수질 및 수생태계 보전에 관한 법률」에서 개정된 법률로 그 목적이 수질과 수생태계로 국한되어 왔다. 하지만 통합물관리 도입으로 인하여 제정된 「물관리기본법」에서는 "국가와 지방자치단체가 물과 관련된 정책을 수립, 시행할 때에는 물순환 과정의 전주기를 고려하여야 한다"고 명시되어 있으며 「물환경보전법」의 물순환관리지표는 수량이 제외되어 물순환 왜곡으로 인한 문제점이 충분히 포함되지 않은 실정이다. 따라서 본 연구에서는 국민들의 안전을 도모하기 위하여 물순환관리지표에 도시유역의 물순환 왜곡으로 인한 수재해 현황을 추가적으로 고려하고자 한다. 수재해 현황은 행정안전부의 자연재해로 인한 최근 10년간 인명피해와 피해액 조사를 바탕으로 가장 심각한 피해를 불러일으킨 폭염과 태풍 및 호우를 고려대상으로 선정하였다. 그 중 도시유역에서의 폭염피해란 불투수면적률이 증가함에 따라 증발산량이 감소하며 발생하는 도심의 열섬현상과 깊은 관계가 있고, 태풍 및 호우피해는 첨두유량의 증가와 도시배수의 연결성에 의하여 발생하는 침수와 깊은 관계가 있기에 이를 본 연구에서의 수량의 대표인자로 결정하였다. 수계 단위의 물순환관리지표와 행정구역 단위의 수재해 현황을 공간적으로 비교하기 위해 면적가중평균법을 이용하여 물순환율과 불투수면적률을 행정구역별로 재척도화를 하였다. 그리고 고려할 요소를 판단하기 위해 행정구역 별 물순환관리지표와 열섬현상, 도시침수를 측정하는 지표의 순위를 매겨 등위상관계수를 계산하였다. 도시침수와 열섬현상을 대표하는 지표 중 물순환율과 상관계수가 낮은 지표부터 물순환관리지표에 포함시켜야 할 요소라고 판단하였으며, 이를 바탕으로 보다 개선된 물순환관리지표를 제안하였다. 기후변화에 따라 현재 수재해 위험성이 더욱 커지고 그의 패턴도 달라지고 있기에 본 연구의 결과를 바탕으로 물순환관리지표가 좀 더 국민들에게 실효성이 있는 평가지표로 개선되기를 기대한다.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.11 no.4
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• pp.293-301
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• 2013

Borehole Disposal Concept (BDC) was initiated by the South African Nuclear Energy Corporation (NECSA) with the view to improve the radioactive waste management practices in Africa. At a time when geological disposal of radioactive waste is being considered, the need to protect ground water from possible radioactive contamination and the investigation of radionuclides migration through soil and rocks of zone of aeration into ground water has becomes very imperative. This is why the Borehole Disposal Concept (BDC) is being suggested to address the problem. The concept involves the conditioning and emplacement of disused sealed radioactive sources in an engineered facility of a relatively narrow diameter borehole (260 mm). Tanzania is operating a Radioactive Waste Management Facility where a number of spent sealed radioactive sources with long and short half lives are stored. The activity of spent sealed radioactive sources range from (1E-6 to 8.8E+3 Ci). However, the long term disposal solution is still a problem. This study therefore proposing the country to adopt the BDC, since the repository requires limited land area and has a low probability of human intrusion due to the small footprint of the borehole.

• Proceedings of the Korea Water Resources Association Conference
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• 2006.05a
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• pp.2-11
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• 2006

In the processes of hydrological cycle, when precipitation reaches the ground surface, water may become surface runoff or infiltrate into soil and then possibly further percolate into groundwater aquifer. A part of the water is returned to the atmosphere through evaporation and transpiration. Soil moisture dynamics driven climate fluctuations plays a key role in the simulation of water transfer among ground surface, unsaturated zone and aquifer. In this study, a one-layer canopy and a four-layer soil representation is used for a coupled soil-vegetation modeling scheme. A non-zero hydraulic diffusivity between the deepest soil layer modeled and groundwater table is used to couple the numerical equations of soil moisture and groundwater dynamics. Simulation of runoff generation is based on the mechanism of both infiltration excess overland flow and saturation overland flow nested in a numerical model of soil moisture dynamics. Thus, a comprehensive hydrological model integrating canopy, soil zone and aquifer has been developed to evaluate water resources in the plain region of Huaihe River basin in East China and simulate water transfer among precipitation, surface water, soil moisture and groundwater. The newly developed model is capable of calculating hydrological components of surface runoff, evapotranpiration from soil and aquifer, and groundwater recharge from precipitation and discharge into rivers. Regional parameterization is made by using two approaches. One is to determine most parameters representing specific physical values on the basis of characterization of soil properties in unsaturated zone and aquifer, and vegetations. The other is to calibrate the remaining few parameters on the basis of comparison between measured and simulated streamflow and groundwater tables. The integrated modeling system was successfully used in the Linhuanji catchment of Huaihe plain region. Study results demonstrate that (1) on the average 14.2% of precipitation becomes surface runoff and baseflow during a ten-year period from 1986 to 1995 and this figure fluctuates between only 3.0% in drought years of 1986, 1988, 1993 and 1994 to 24.0% in wet year of 1991; (2) groundwater directly deriving from precipitation recharge is about 15.0% t of the precipitation amount, and (3) about half of the groundwater recharge flows into rivers and loses through evaporation.

• Journal of Korea Water Resources Association
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• v.42 no.12
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• pp.1103-1111
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• 2009

This study derived the analysis results of alternatives for integrated watershed management under urbanization and climate change scenarios. Climate change and urbanization scenarios were obtained by using SDSM (Statistical Downscaling Method) model and ICM (Impervious Cover Model), respectively. Alternatives for the Anyangcheon watershed are reuse of wastewater treatment plant effluent, and redevelopment of existing reservoir. Flow and BOD concentration duration curves were derived by using HSPF (Hydrological Simulation Program - Fortran) model. As a result, low flow ($Q_{99},\;Q_{95},\;Q_{90}$) and BOD concentration ($Q_{10},\;Q_5,\;Q_1$) were very sensitive to the alternatives comparing to high flow($C_{30},\;C_{10},\;C_1$). Although urbanization makes the hydrological cycle distorted, effective alternatives can reduce its damage. The numbers of days to satisfy the instreamflow requirements and target water quality were also sensitive to urbanization. This result showed that the climate change and urbanization should be considered in the water resources/watershed and environmental planning.