• Title/Summary/Keyword: virtual fit

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Identification of Anti-Cancer Targets of Eco-Friendly Waste Punica granatum Peel by Dual Reverse Virtual Screening and Binding Analysis

  • Usha, Talambedu;Goyal, Arvind Kumar;Lubna, Syed;Prashanth, H.P.;Mohan, T. Madhan;Pande, Veena;Middha, Sushil Kumar
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.23
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    • pp.10345-10350
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    • 2015
  • Background: Punica granatum (family: Lythraceae) is mainly found in Iran, which is considered to be its primary centre of origin. Studies on pomegranate peel have revealed antioxidant, anti-inflammatory, anti-angiogenesis activities, with prevention of premature aging and reducing inflammation. In addition to this it is also useful in treating various diseases like diabetes, maintaining blood pressure and treatment of neoplasms such as prostate and breast cancer. Objectives: In this study we identified anti-cancer targets of active compounds like corilagin (tannins), quercetin (flavonoids) and pseudopelletierine (alkaloids) present in pomegranate peel by employing dual reverse screening and binding analysis. Materials and Methods: The potent targets of the pomegranate peel were annotated by the PharmMapper and ReverseScreen 3D, then compared with targets identified from different Bioassay databases (NPACT and HIT's). Docking was then further employed using AutoDock pyrx and validated through discovery studio for studying molecular interactions. Results: A number of potent anti-cancerous targets were attained from the PharmMapper server according to their fit score and from ReverseScreen 3D server according to decreasing 3D scores. Conclusion: The identified targets now need to be further validated through in vitro and in vivo studies.

ATM Network Survivability Enhancement Scheme using Disjoint VP Groups (분리 VP 그룹을 이용한 ATM 망 생존도 향상 방안)

  • Lee, Gil-Heung;Choe, Yong-Hun;Park, Won-Seo;Lee, Jae-Yong;Lee, Sang-Bae
    • Journal of KIISE:Computer Systems and Theory
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    • v.26 no.8
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    • pp.949-956
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    • 1999
  • 이 논문에서는 ATM (Asynchronous Transfer Mode) 방식의 초고속망의 장애 발생 시 이용자 연결의 QoS (Quality of Service)를 고려하여 복구할 수 있게 하는 보호 망 설계 방안을 제시한다. 제시한 설계 방안에 기초한 비용과 복구 특성을 분석과 모의 실험을 통해 알아본다. 제안하는 망에서의 복구는 분리 VP 그룹 (Disjoint Virtual Path Group, DVPG) 을 사용하는 상태 독립적 (State- independent) 방식으로 복구된다. ATM 망의 운용 및 보호 VP 할당과 용량 배정 문제를 정의하고 이를 바탕으로 최소의 비용을 갖는 VP 망을 설계한다. 망의 고장 시 기존 노드간의 VP 연결은 미리 할당된 링크 또는 노드 분리 보호 VP 경로를 따라 간단한 복구 알고리즘에 의해 빠르게 복구된다. QoS의 고려는 추가 비용을 필요로 하지만 정확한 이용자 연결의 복구를 실현하며, 분리 VP 그룹의 적용은 비용을 상승시키지만, 빠른 복구와 복수의 고장에 대처할 수 있는 방안이 된다.Abstract A cost evaluation of protection scheme for VP-based ATM network is presented here and its related characteristics are evaluated. The proposed and evaluated scheme is a state-independent restoration scheme using a disjoint path group. For fast and simple restoration of failed connections, link disjoint or node disjoint VP groups (DVPG) were utilized in this paper. A VP assignment and capacity planning problem is formulated. When failure occurs, the failed working VPs are switched to the protection VPs of disjoint path groups with a simple restoration scheme. And, cost evaluation and restoration characteristics are presented. The consideration of multiple QoS (Quality of Service) levels and disjoint path group protection scheme require additional network cost but acquire fit and fast restoration.

E-Business and Simulation

  • Park, Sung-Joo
    • Proceedings of the Korea Society for Simulation Conference
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    • 2001.10a
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    • pp.9-10
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    • 2001
  • Simulation has been evolved with the advance of computer and technique of modeling application systems. Early simulations were numerical analysis of engineering models known as continuous simulation, analysis of random events using various random number generators thus named as Monte Carlo simulation, iud analysis o(\\\\`queues which are prevalent in many real world systems including manufacturing, transportation, telecommunication. Discrete-event simulation has been used far modeling and analyzing the systems with waiting lines and inefficient delays. These simulations, either discrete-event, continuous, or hybrid, have played a key role in industrial age by helping to design and implement the efficient real world systems. In the information age which has been brought up by the advent of Internet, e-business has emerged. E-business, any business using Internet, can be characterized by the network of extended enterprises---extended supply and demand chains. The extension of value chains spans far reaching scope in business functions and space globally. It also extends to the individual customer, customer preferences and behaviors, to find the best service and product fit for each individual---mass customization. Simulation should also play a key role in analyzing and evaluating the various phenomena of e-business where the phenomena can be characterized by dynamics, uncertainty, and complexity. In this tutorial, applications of simulation to e-business phenomena will be explained and illustrated. Examples are the dynamics of new economy, analysis of e-business processes, virtual manufacturing system, digital divide phenomena, etc. Partly influenced by e-business, a new trend of simulation has emerged called agent-based simulation, Agent-based simulation is a technique of simulation using software agent that have autonomy and proactivity which are useful in analyzing and integrating numerous individual customer's behavior. One particular form of agent-based simulation is swarm. This tutorial concludes with the illustration of swarm or swarm Intelligence applied to various e-business applications, and future directions and implications of this new trend of simulation.

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Hole-Filling Method Using Extrapolated Spatio-temporal Background Information (추정된 시공간 배경 정보를 이용한 홀채움 방식)

  • Kim, Beomsu;Nguyen, Tien Dat;Hong, Min-Cheol
    • Journal of the Institute of Electronics and Information Engineers
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    • v.54 no.8
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    • pp.67-80
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    • 2017
  • This paper presents a hole-filling method using extrapolated spatio-temporal background information to obtain a synthesized view. A new temporal background model using non-overlapped patch based background codebook is introduced to extrapolate temporal background information In addition, a depth-map driven spatial local background estimation is addressed to define spatial background constraints that represent the lower and upper bounds of a background candidate. Background holes are filled by comparing the similarities between the temporal background information and the spatial background constraints. Additionally, a depth map-based ghost removal filter is described to solve the problem of the non-fit between a color image and the corresponding depth map of a virtual view after 3-D warping. Finally, an inpainting is applied to fill in the remaining holes with the priority function that includes a new depth term. The experimental results demonstrated that the proposed method led to results that promised subjective and objective improvement over the state-of-the-art methods.

CPS(Cyber Physical System) & Research Opportunities for MIS (CPS(Cyber Physical System)와 MIS의 연구기회 탐색)

  • Choi, Moo-Jin;Park, Jong-Pil
    • The Journal of Information Systems
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    • v.26 no.4
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    • pp.63-85
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    • 2017
  • Purpose Recently, much attention in building smart factory has dramatically increased with an emergence of the Industry 4.0. As we noted a connectivity gap between main concerns of MIS and the automated manufacturing systems such as POP and MES, it is recommended that CPS (Cyber-Physical System) can be an important building block for the smart factory and enrich the depth of MIS knowledge. Therefore, first, this study attempted to identify the connectivity gap between the traditional field of MIS (ERP, SCM, CRM, etc.) and the automated manufacturing systems, and then recommended CPS as a technical bridge to fill the gap. Secondly, we studied concepts and research trend of CPS that is believed to be a virtual mechanism to manage manufacturing systems in an integrated manner. Finally, we suggested research and educational opportunities in MIS based on the CPS perspectives. Design/methodology/approach Since this paper introduced relatively new idea of CPS originally discussed in the field of engineering, traditional MIS research method such as survey and experiment may not fit well. Therefore this research collected technical cases through literature survey in engineering fields, video clips from Youtube, and field references from various ICT Exhibitions and Conventions. Then we analyzed and reorganized them to highlight the necessity of CPS and draw some insight to share with MIS academia. Findings This paper introduced CPS to bridge the connectivity gap between the traditional MIS and automated manufacturing system (smart factory), a concern far away from the MIS academia. Further, this paper suggested future research subjects of MIS such as developing software to share big production data and systems to support manufacturing decisions, and innovating MIS curricula including smart and intelligent manufacturing technology within the context of traditional enterprise systems.

Study Curation Service Utilizing th Learner Pattern Information from the Smart Learning (스마트러닝에서의 학습자 패턴 정보를 활용한 큐레이션 서비스 제공 방안 연구)

  • Yun, Jun-soo;Hwang, Hyun-seo;Park, Jin-tae;Seo, Kyoung-teak;Moon, Il-young;Kwon, Oh-young;Kim, Byeong-jun
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2015.05a
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    • pp.903-906
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    • 2015
  • Over the recent industry -wide virtual world and the real world, broadcasting and telecommunications, IT technology and traditional industries, such as the fusion research has been conducted in a variety of fields. And training in the field of education is changing the paradigm of creativity to break the intrusive training center. In addition, the quality of interactive educational content technology to foster self-directed future talent is a situation that is required. The market has already surpassed the smartphone PC, smart devices and e-learning technologies are appearing new service called 'smart learning' as a new form of convergence of the educational system. In this paper, based on the direct development of a content authoring applications and Web sites, and cloud environments to the students collect and analyze patterns. Utilizing this information, we studied the curation service plans that recommend the appropriate content to fit the tastes of the learner.

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The Effects of Experience Factors have on Store Satisfaction and Store Loyalty for Experimental Fashion Stores - Focusing on Virtual Experience by Visual Stimuli - (체험적 패션 매장에서 체험 요인이 점포만족도와 점포충성도에 미치는 영향 연구 - 시각적 자극물을 통한 가상 체험을 중심으로 -)

  • Chae, Heeju;Kim, Minyoung;Ko, Eunju
    • Journal of the Korean Society of Costume
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    • v.66 no.4
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    • pp.1-17
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    • 2016
  • Fashion stores have to change to fit such the taste of individual customers taste and try to give unique experiences to the customers. They need to develop a special space that entertains customers, and entices them to visit and revitalize the off-line stores. This paper aims to analyze the experimental factors of stores, and how each of the factors impact customer experience in order to find out its effect on store satisfaction and store loyalty. Data was analyzed by using SPSS 18.0 and AMOS 18.0. Results of this study are as follows. First, Visual, Tactile, and Gustatory are the main senses that influence the emotional experience of the customers on a store visit. Second, three factors that influenced customer experience in experimental fashion stores are 'Causing Interest', 'Causing Concern', and 'Causing Relationship.' Third, the 'Causing Interest' factor and the 'Causing Concern' factor showed positive correlation with store satisfaction, while the 'Causing Relationship' factor did not impact store satisfaction, which affected store loyalty. Fourth, each experimental fashion stores can have different effect to consumer satisfaction and loyalty. Also, fashion store brands without an experimental store can cause various effects to consumers when a flagship store with an array of product information is formed. The conclusion drawn from this study will provide a guideline for fashion stores attract faithful customers by improving their store environment.

The Characteristics of Fashion Design as a Playing through a Doll (인형 놀이에 나타난 패션 디자인의 특성)

  • Lee, Ji-Hyun;Kim, Young-In
    • Journal of the Korean Society of Costume
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    • v.57 no.2 s.111
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    • pp.86-99
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    • 2007
  • In this study, the concept of play as an entertainment is redefined and applicable method of fashion design as a play are suggested by analyzing the feature of doll's costume design based on the play pattern. In literary study, the role of playing doll Is described and has been examined by the analysis of scholars' opinions. In positive study, the pattern and costume design of sample costume dolls are analyzed using 624 samples of the representative images collected from the literatures and real figures, and they are classified as collection dolls or fashion dolls in order to analyze the feature of fashion design in playing dolls. As a result of the analysis of doll's costumes based on its use, the costumers are divided into a real world costume which is similar to what human wear in daily life and a virtual costume which is used in the movie or play and the costumes only worn by the dolls. The examination of the type of costume worn by dolls, dress is principally dominant costume in collection doll, whereas in fashion doll, dress is still mainly worn but shirt blouse & pants, shirt blouse k skirt, jacket, coat, bathing suit. etc. are shown dispersedly as well. In the costume silhouette of dolls, collection doll uses mostly A line silhouette meanwhile fit and flare is mostly used in the fashion doll but other silhouettes are also relatively shown a lot. In the means of the color of the costume worn by dolls, collection doll is more similar to those in actual fashion design. On the contrary, the color of the costume that fashion doll is put on is more free and more various because the trendy rotors such as green, yellow, purple, etc are used.

Comparison of bodice prototypes of adolescent male students using 3D virtual simulation program (3D 가상착의 프로그램을 활용한 청소년 남학생의 보디스 원형 비교)

  • Cha, Su-Joung
    • The Research Journal of the Costume Culture
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    • v.26 no.5
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    • pp.727-743
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    • 2018
  • In this study, we used the 3D simulation program to create bodice patterns for adolescents boy students and analyze the fitting and air gap through 3D simulation. The purpose of this study was to select the bodice pattern method that best suited the body shapes of the adolescents male students. The subjects of this study were the French E pattern, Japanese N pattern, and Korean industrial L and J patterns. The applied size was the sixth Korean human body size survey data of 2010 Korea. The age range of the subjects was 13-18 years. DC Suite Program Ver. 5.1 was used, and SPSS 23.0 program was used for data analysis. As a result of comparing the shapes of the bodice patterns in the 3D simulation program, the E pattern had two waist darts on the front and one shoulder dart and one waist dart on the back, and the J and L patterns only had one dart on the back. The N pattern had no darts on either the front or back. As a result of examining the appearance evaluation of the pattern, air gap, color distribution, and clothing cross-section, the E pattern was evaluated as the closest to the body, and the N pattern was evaluated as the pattern with the largest allowance. The J pattern was evaluated as the best fit for body shape of the male adolescents. However, it is necessary to develop a pattern system by adding extra ease in setting the center front length.

A Study on Sizing System and Preferable Ease in a Men's Dress Shirt for Virtual Mass Customization System (가상공간의 대량맞춤 생산을 위한 남성 드레스셔츠 치수체계와 선호 여유량에 관한 연구)

  • Jang, Sung-Eun
    • Journal of the Korean Society of Clothing and Textiles
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    • v.32 no.1
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    • pp.99-109
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    • 2008
  • The purpose of this study was to survey sizing system and preferable ease and to decide the body measuring items for pattern making in a men's dress shirt for mass customization industry that is rising to the surface as a new production system. For this, it had a survey subjects were 254 males between 25 to 44 years old who wear dress shirt frequently and the relevant on line companies, and analyzed the garment sizing system and preferable ease. Collected data were analysed by frequency analysis, t-test, $X^2-test$, and ANOVA using SPSS 12.0 for window. Garment pattern making should reflect the sizes of the body parts well, and simplification of the ordering process would work as an important variable. In relation to the preferable ease, older people preferred more ease while younger people preferred fit ease. In relation to the sizes, people wearing the size of '110' preferred more ease than the size of '90'. And people weighing over 90kg preferred sufficient ease than less weighing. People height over 170cm people preferred sufficient ease for the length between shoulders than height under 170cm. In case of the companies had no consistent sizing system. Significant difference was found in the sizes, except for the size of '100', among those companies, there was significant difference in the length between shoulders and the length of the shirt among those companies and those sizes. Significant body parts for a garment pattern making was height, the circumference of the neck, the chest circumference, the length between biacromion, the arms length, and the waist circumference.