• 보건행정학회지
• /
• 제31권3호
• /
• pp.292-300
• /
• 2021

Background: Medication adherence in hypertension is the most important to control blood pressure and prevent major complications. The purpose of this study was to identify factors affecting medication adherence and to examine the relationship between medication adherence and blood pressure control in Korea. Methods: This study used data from the 7th Korea national health and nutrition examination survey (2016-2018) of the Korea Disease Control and Prevention Agency. We selected 4,063 hypertensive patients from the data. And we choose socio-demographic, health behavior, healthcare utilization, and severity characteristics as hypertensive patient characteristics. Results: Of the patients with hypertension, 92.3% had shown adherence to medication as of 2016-2018 and shows variation according to the characteristic of patients. The cases with male, under 50 years old, urban area, single household, unmet medical services, less than 5 years of hypertension duration, no comorbidities (diabetes mellitus, myocardial infarction) showed significantly low medication adherence. After adjusting for confounders, adherent patients tended to have lower current systolic blood pressure (β=-10.846, p<0.001) and diastolic blood pressure (β=-5.018, p<0.001) than nonadherent patients. And, adherent patients increased the control odds of blood pressure compared with nonadherent patients (odds ratio, 3.02; 95% confidence interval, 2.21-4.12). Conclusion: This study confirmed that adherence to antihypertensive drugs was effective in controlling blood pressure. In order to more actively manage hypertensive patients at the national level, it is necessary to make an effort to improve the medication compliance of nonadherent groups, such as early-diagnosis patients, young patients under 50 years of age, and patients living alone.

• Journal of Korean Neurosurgical Society
• /
• 제65권5호
• /
• pp.652-664
• /
• 2022

The Kernohan-Woltman notch phenomenon (KWNP) refers to an intracranial lesion causing massive side-to-side mass effect which leads to compression of the contralateral cerebral peduncle against the free edge of the cerebellar tentorium. Diagnosis is based on "paradoxical" motor deficit ipsilateral to the lesion associated with radiologic evidence of damage to the contralateral cerebral peduncle. To date, there is scarce evidence regarding KWNP associated neuroimaging patterns and motor function prognostic factors. A systematic review was conducted on Medline database from inception to July 2021 looking for English-language articles concerning KWNP, in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The research yielded 45 articles for a total of 51 patients. The mean age was 40.7 years-old and the male/female sex ratio was 2/1. 63% of the patients (32/51) suffered from head trauma with a majority of acute subdural hematomas (57%, 29/51). 57% (29/51) of the patients were in the coma upon admission and 47% (24/51) presented pupil anomalies. KWNP presented the neuroimaging features of compression ischemic stroke located in the contralateral cerebral peduncle, with edema in the surrounding structures and sometimes compression stroke of the cerebral arteries passing nearby. 45% of the patients (23/51) presented a good motor functional outcome; nevertheless, no predisposing factor was identified. A Glasgow coma scale (GCS) of more than 3 showed a trend (p=0.1065) toward a better motor functional outcome. The KWNP is a regional compression syndrome oftentimes caused by sudden and massive uncal herniation and leading to contralateral cerebral peduncle ischemia. Even though patients suffering from KWNP usually present a good overall recovery, patients with a GCS of 3 may present a worse motor functional outcome. In order to better understand this syndrome, future studies will have to focus on more personalized criteria such as individual variation of tentorial notch width.

• 전기학회논문지
• /
• 제62권7호
• /
• pp.1009-1013
• /
• 2013

In this study, we developed a fiber-optic goniometer for the continuous measurement of knee joint angle which provides important medical information on Alzheimer's disease. The fiber-optic goniometer is composed of a light-emitting diode (LED), a plastic optical fiber (POF), and a voltage output photodiode (PD). As a sensing part of the fiber-optic goniometer, a unclad fiber with regular intervals of 1 mm was fabricated to improve efficiency of bending loss according to the angle variation of knee joint. The emitting light with a center wavelength of 470 nm from a LED is guided by a POF to the PD, the transmitted light is then attenuated by the bending loss inside the bent POF. The intensity variation of the light transmitted from the POF gives rise to a change in output voltage in the fiber-optic goniometer. Therefore, we measured the real-time output voltage of the proposed fiber-optic goniometer using the unclad fiber according to the knee joint angle. Through the repeated experiments, the fiber-optic goniometer shows that it has a reversibility and a wide measurable angle range.

• Journal of Yeungnam Medical Science
• /
• 제29권1호
• /
• pp.48-53
• /
• 2012

Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths in South Korea. To decrease its mortality rate, its early detection is very important. Screening for HCC detection has been accepted as the management modality for patients with chronic liver disease. Reported herein is a case involving the marked rapid growth of HCC detected at an advanced stage in a screening test with a 3 months interval. A 49-year-old male patient with chronic hepatitis B was admitted to the hospital due to a liver mass detected on CT scan. The patient underwent a first CT scan 3 months earlier, and no tumor was detected. Follow-up CT scan was performed and showed a 9.1 cm HCC with portal vein thrombosis. Percutaneous liver biopsy was performed, and the diagnosis of hepatocellular carcinoma was confirmed. In the pertinent guidelines, the recommended screening interval for HCC is 6-12 months, but the screening interval and additional diagnostic methods should be considered due to the variation in the HCC growth rate according to the patient's clinical characteristics.

• 한국지반환경공학회 논문집
• /
• 제11권12호
• /
• pp.27-35
• /
• 2010

지하공간에 설치되는 구조물 중 지하수위 아래에 위치하는 부분은 상향으로 정수압인 부력이 작용하게 된다. 최근 큰 규모의 중요구조물 즉, 부력이 크게 발생하는 구조물은 공사비가 고가이나 안전율을 확실하게 증가시키는 방법인 부력저항 영구앵커를 많이 적용하고 있는 실정이다. 그러나, 부력저항 영구앵커의 저항 메커니즘 규명은 미흡한 실정이다. 특히, 시공 후 앵커의 장기거동에 대한 규명은 계측 관리의 어려움으로 이루어지지 않고 있는 것이 현실이다. 본 연구에서는 부력 저항 영구앵커의 설계 시 합리적인 구조물 거동 평가를 위하여 앵커두부에 하중계를 설치하여 앵커축력을 자동화계측 및 수동계측을 통해 시공초기부터 10년간 계측 분석하였으며, 이를 토대로 건물의 자중증가에 따른 앵커의 시공단계별 거동과 시간 경과에 따른 앵커의 장기거동(시공 후 10년 이내의 거동)을 분석하였다.

• 대한의용생체공학회:의공학회지
• /
• 제40권2호
• /
• pp.62-67
• /
• 2019

The purpose of this study was to evaluate the performance of deep neural network model in order to determine whether there is a risk factor for coronary artery disease based on the cardiac variation parameter. The study used unidentifiable 297 data to evaluate the performance of the model. Input data consists of heart rate parameters, which are SDNN (standard deviation of the N-N intervals), PSI (physical stress index), TP (total power), VLF (very low frequency), LF (low frequency), HF (high frequency), RMSSD (root mean square of successive difference) APEN (approximate entropy) and SRD (successive R-R interval difference), the age group and sex. Output data are divided into normal and patient groups, and the patient group consists of those diagnosed with diabetes, high blood pressure, and hyperlipidemia among the various risk factors that can cause coronary artery disease. Based on this, a binary classification model was applied using Deep Neural Network of deep learning techniques to classify normal and patient groups efficiently. To evaluate the effectiveness of the model used in this study, Kernel SVM (support vector machine), one of the classification models in machine learning, was compared and evaluated using same data. The results showed that the accuracy of the proposed deep neural network was train set 91.79% and test set 85.56% and the specificity was 87.04% and the sensitivity was 83.33% from the point of diagnosis. These results suggest that deep learning is more efficient when classifying these medical data because the train set accuracy in the deep neural network was 7.73% higher than the comparative model Kernel SVM.

• Imaging Science in Dentistry
• /
• 제50권4호
• /
• pp.281-290
• /
• 2020

Purpose: The objective of the present study was to evaluate the prevalence of dental implants positioning errors and their associations with adjacent structures and anatomical variations by means of cone-beam computed tomography (CBCT). Materials and Methods: CBCT images of 207 patients (584 dental implants) were evaluated by 2 oral radiologists. The distance between the implant and the adjacent teeth/implants was measured and classified as adequate (≥1.5 mm and ≥3 mm, respectively) or inadequate. The presence of thread exposure, cortical perforation, implant dehiscence, implant penetration into adjacent structures, and anatomical variations was also recorded. The incisor canal diameter and the depth of the concavity of the submandibular fossa were measured in order to evaluate their correlations with the frequency of implant penetration in these structures. Descriptive analyses, the Fisher exact test, and Spearman correlation analysis were performed (α=0.05). Results: The overall prevalence of positioning errors was 82.9%. The most common error was the inadequate distance between the implant and the adjacent teeth/implants. The presence of anatomical variations did not significantly influence the overall prevalence of errors (P>0.05). There was a positive correlation between the diameter of the incisor canal and the frequency of implant penetration in this structure (r=0.232, P<0.05). Conclusion: There was a high prevalence of dental implant positioning errors, and positioning errors were not associated with the presence of anatomical variations. Professionals should be aware of the space available for implant placement during the preoperative planning stage.

• 대한영상의학회지
• /
• 제81권3호
• /
• pp.467-487
• /
• 2020

뇌종양의 진단 및 치료 반응 평가의 기본이 되는 영상기법은 해부학적 영상이다. 현재 임상에서 사용 가능한 영상기법들 중 확산 강조 영상 및 관류 영상이 추가적인 정보를 제공하고 있다. 최근에는 종양의 유전체 변이와 이질성 평가가 중요해지면서 라디오믹스와 딥러닝을 이용한 영상분석기법의 임상 응용이 기대되고 있다. 본 종설에서는 뇌종양 영상 임상 적용에서 여전히 중요한 해부학적 영상을 중심으로 한 자기공명영상 촬영 권고안, 최신 영상기법 중 확산 강조 영상 및 관류 영상의 기본 원리, 병태생리학적 배경 및 임상응용, 마지막으로 최근 컴퓨터 기술의 발전으로 많이 연구되고 있는 라디오믹스와 딥러닝의 뇌종양에서의 향후 활용가치에 대해 기술하고자 한다.

• Journal of Acupuncture Research
• /
• 제27권4호
• /
• pp.67-84
• /
• 2010

Objectives : To review RCTs on acupuncture treatment for shoulder pain in order to establish a standard acupuncture treatment model in treating shoulder pain. Methods : RCT articles on traditional acupuncture treatment for shoulder pain were searched through online database. Quality of studies were assessed using the FEAS and the modified Jadad score. Results : Eighteen trials of acupuncture for shoulder pain were analyzed. Based on the results of these reviews the following factors might contribute to optimal results from acupuncture treatment. 1) Usage of LI, SI, TE meridians, usage of $LI_{15}$, $TE_{14}$, $GB_{21}$, $LI_{11}$, $LI_4$, $SI_{14}$, $LI_{14}$, $TE_{15}$ acupuncture points. 2) More than four acupuncture points should be used. 3) More than 15 minutes of needle retention time. 4) Needle length-40mm and diameter-0.30mm. 5) More than 9 times treatment 6) More than 5 weeks treatment duration. Conclusions : There was no relation between quality of article and effectiveness of acupuncture. To improve the remedial value, it is necessary to mention De-qi, stimulation of acupuncture and correct variation in diagnosis with the above-mentioned. It is better that clinical trials of acupuncture treatment is designed that type of RCT and double blind. Also when it is set that sham nonpenetrating acupuncture, no treatment group as a control group, and participants don't distinguish wheather acupuncture treatment or not, it will be more meaningful.

• KSBB Journal
• /
• 제15권3호
• /
• pp.243-246
• /
• 2000

B형간염 바이러스 연구에 관한 최근의 주제는 혈중 B형간염 표면항원농도(HBsAg)를 예후 판정의 지표로 활용하는 것이다, 본 연구에서는 B형간염에 대한 자가진단을 목적으로 하여 컴퓨 터 상 분석 기법을 사용하는 HBsAg에 대한 정량적 면역크로마 토그래피 측정법을 개발하였다. 본 방법을 사용하였을 때 측정 된 integrated optical density(IOD)은 2~200 ng/mL의 범위 내에 서 표준 HBsAg 농도의 log값에 비례하여 증가하였데, ELISA 측정법은 0.1~100 ng/mL의 범위 내에서 표준 HBsAg 농도의 log값에 비례하여 증가하였다. 3개의 혈청 겸제를 가지고 두 가 지의 측정법으로 각각 시험하여 표준곡선에 대입하였을 때 동일 한 농도를 나타내 었는데 그 값이 각각 9,000, 7,000, 4,000 ng/mL 이었다. 또한 컴퓨터 상 분석 기법을 사용하는 HBsAg에 대한 정량적 면역크로마토그래피 측정법으로 동일 겸체를 5회 반복 시험하였을 때 측정된 IOD값이 재현성이 있었으며, 변이계수가 1.38 ~ 6.30% 이내였다.