• Title/Summary/Keyword: variant

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Evaluation of Norudia® HbA1c Kit for Glycohemoglobin Assay (당화혈색소 측정을 위한 Norudia® HbA1c 키트의 평가)

  • Hong, Seung-Bok;Kim, Eun-Joong
    • Korean Journal of Clinical Laboratory Science
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    • v.41 no.1
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    • pp.37-41
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    • 2009

  • Measurement of hemoglobin A1c is used as an objective indicator of long-term blood glucose control in diabetic patients. We evaluated recently introduced Norudia$^{(R)}$ HbA1c (Daiichi Pure Chemical Co. Ltd, Tokyo, Japan) test reagent using enzyme method for HbA1c assay. Linearity, precision and correlation with VARIANT$^{TM}$ II Turbo HbA1c analyzer (BIO-RAD, Hercules, CA, USA) were evaluated. The reference range was determined from 201 healthy subjects. The Norudia$^{(R)}$ HbA1c test reagent was founded to be linear in a range of 5.6% to 14.0% ($r^2=0.9885$). The within-run and between-day precision were 0.954% and 1.03% for low level (HbA1c 5.24%), 0.67% and 1.28% for high level (HbA1c 9.01%), respectively. Comparison study between Norudia$^{(R)}$ HbA1c test reagent and VARIANT$^{TM}$ II Turbo showed good correlation with a slope of 1.0489. an intercept at -0.9717, and coefficient of correlation was 0.9907. The reference range of HbA1c obtained from this reagent was 4.07-5.50%. The Norudia$^{(R)}$ HbA1c test reagent showed good linearity, precision and correlation with HbA1c analyzer with HPLC method. In addition, the exclusive analyzer is not required for assay and then this kit may be useful for HbA1c assay in clinical laboratory.

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A Scheme on Internet-based Checking for Variant CNC Machines in Machine Shop

  • Kim, Dong-Hoon;Kim, Sun-Ho;Koh, Kwang-Sik
    • 제어로봇시스템학회:학술대회논문집
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    • 2004.08a
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    • pp.1732-1737
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    • 2004

  • This paper proposes Internet-based checking technique for machine-tools with variant CNC (Computerized Numerical Controller). According to the architecture of CNC, CNC is classified into two types such as CAC (Closed Architecture Controller) which is conventional CNC, and OAC (Open Architecture Controller) which is a recently introduced PC-based controller. CAC has a closed architecture and it is dependent on CNC vender specification. Because of this, it has been very difficult for users to implement an application programs in CNC domain. Therefore, an additionally special module is required for Internet-based application such as remote checking. In this case, web I/O embedded module can be efficiently applied for Internet-based checking. The module is directly attached to TCP/IP network for communication. In order to obtain the monitoring data of CNC machines, the I/O signals of the module are assigned to PLC (Programmable Logic Controller) input and output (I/O) signals within CNC domain. On the other hand, OAC has a PC-based open architecture and an additional module is not necessary for the connection with external site. Because of this, a simple DAU is just used for signal sensing and data acquisition without additional communication modules. For Internet-based remote checking of machine-tools with OAC, a user-defined daemon and application programs are implemented as the form of internal function within the PC-based controller. Internet communication is performed between the daemon program in CNC domain and web script programs in external server. Checking points defined in this research are classified into two categories such as structured point and operational point. The formal includes the vibration of bearing, temperature of spindle unit and another periodical management. And the latter includes oil checking, clamp locking/unlocking and machining on/off status.

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STAT6 Gene Polymorphisms in Allergic Rhinitis

  • Kim, Jeong Joong;Kim, Min Su;Lee, Jung Hun;Choi, Tae Wook;Choi, Sang Heon;Lee, Jae Hoon;Chung, Hun Taeg
    • Genomics & Informatics
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    • v.2 no.3
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    • pp.126-130
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    • 2004

  • T helper-type 2 cytokines, such as IL-4 and IL-13, may play a central role in allergic diseases. The protein known as signal transducers and activators of transcription 6 (STAT6) is a key transcription factor involved in both IL-4- and -13-mediated biological responses. Two polymorphisms of the STAT 6 gene (exon 1 and G2964A variant) have been found. We investigated whether these STAT6 gene polymorph isms were associated with allergic rhinitis. Blood samples for genetic analysis were obtained from 285 individuals with allergic rhinitis and from 271 healthy subjects without atopic disease. The G2964A variant of the STAT6 gene was genotyped using PCR-RFLP analysis. The GT repeat polymorphism in exon 1 of the STAT6 gene was genotyped by fragment analysis. There was no association between the 2964A variant and GT repeat polymorphism in exon 1 of the STAT6 and allergic rhinitis in a Korean population (both p > 0.05). Our results suggest that a combination of STAT6 gene polymorphisms is not a useful marker for predicting allergic rhinitis.

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A Design and Implementation of XML Document storing and retrieval Framework based on a variant k-ary complete tree and RDF Metadata (가변 K진 완전트리와 RDF메타정보에 기반한 XML문서 저장 및 검색 프레임워크의 설계 및 구현)

  • 김규태;정회경;이수연
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.7 no.4
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    • pp.612-622
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    • 2003

  • This paper studied and proposed a XML document storing-and-retrieval framework based on a variant k-ary complete tree and a RDF metadata, which is composed of an effective storing module to store xml documents, a retrieving module to retrieve xml documents, and a connecting module to make this system intemperate in the web environment. In this storing module, DTD independent DOM based decomposition model using a method of addressing unique ill using a variant k-ary complete tree is adopted and is implemented. Query Processing Module includes a XPath query process and a content based retrieval function using word index for content information. To retrieve more exactly data, a structural retrieval using RDF metadata is adopted and implemented. In order to implement effectively XML document storing and retrieval system in the web environment, API using XML-RPC, API using HTTP's GET, PUT, POST and API using SOAP have been adopted and implemented.

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