• Title/Summary/Keyword: value circulation

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Effect of Geijibokryunghwan and each constituent herb on inhibition of platelet aggregation (계지복령환(桂枝茯笭丸) 및 그 구성약물(構成藥物)의 혈소판응집억제(血小板凝集抑制)에 관(關)한 연구(硏究))

  • Kim, Jong-Goo;Park, Sun-Dong;Park, Won-Hwan
    • The Journal of Dong Guk Oriental Medicine
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    • v.8 no.2
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    • pp.115-129
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    • 2000
  • The cause that the increase of animality fat intakes, under exercise, fatness, adding the stress, advanced age etc., the occurrence rate of the circulation system disease has been increased. And the thrombosis importantly came to the front as the risk factor of these circulation system's disease. Nowadays, the ischemic disease has especially discussed, for example the angina or myocardial infarction, originated in thrombosis that came from the platelet aggregation. In the western medicine, as the cure and prevention, using the aspirin or ticlopidine for platelet aggregation suppressant. But in the , the curing method must be used properly according to the pectoralgia or heartache's kind, state, grade. The platelet do not attache to the normal hemangioendothelial cell. But when it stimulated by endothelium peronia and so on, it attache to the injury endothelium or rise aggregation between the platelet. On this time, it secrete the platelet aggregation inducer as like ADP, thromboxane A2 from the inside of platelet. So it has first defensive function through the aggregation augment that prevent the celerity consumption of blood. But the activation of abnormal platelet occur the platelet grume and thrombogenesis. So it bring up the occlusive angiosis, so to speak, cardiovascular disease, cerebrovascular disease, arterial sclerosis. In oriental medicine, the thrombosis in the category of blood stasis and this blood stasis present the generalise or local blood circulation disturbance that generated by all kinds of pathological fact or blood stream retention accompanying with a series of syndrome. As the syndrome, stabbing pain fixed at certain region, squamous and dry skin, fullness and pain of the chest and hypochondrium, firmness and fullness of the lower abdomen, black stool, dark purple tongue or with ecchymoses and petechiae etc.. has been created. And it becomes the pathopoiesis cause that the convulsion and palpitation, severe palpitatiion, tympanites, the symtom complex with a mass or swelling in the abdomen, insanity, stricken by wind etc.. Moreover, it used the drugs for invigorating blood circulation and eliminating blood stasis or drugs for removing blood stasis for all kinds of syndrome through the blood stasis. And the drugs for activating the blood circulation, such as Salviae Radix, Angelicae Sinensis Radix, Persicae Semen, Achyranthis Radix, Cnidii Rhizoma, Carthami Flos are used for that. And it is used to the herbs of insects that has strong effect about the disintergrating blood stasis such as Hirudo, Scolopendrae Corpus, Buthus, Lumbricus etc.. On this study, It used Geijibokryunghwan(GBH) and the consisting herbs to investigate the influence of platelet aggregation about drugs that used to improvement various symptoms created by the thrombosis in oriental medicine. GBH formula has as formula recorded in the , action of 'eleminating the evil and not impairment of healthy energy' and 'promoting the flow of QI and cold and heat, so used for the expel blood stasis herbs from the ancient. Therefore we investigated the restraint effect of GBH and the consisting herbs about the platelet agregation induced to the ADP, AA or collagen. The conclusion is following. 1. When it added the aggregation inducer after that it added GBH and individual consisting herbs in the PRP, GBH showed the (+) inhibition effect on the platelet aggregation and it showed the (+) inhibition effect in the individual consisting herbs as like Paeoniae Radix and Moutan Cortex Radicis. 2. It showed the (+), (+,++) inhibition effect on the platelet aggregation in Paeoniae Radix Hoelen, Paeoniae Radix Moutan Cortex Radicis, Hoelen Moutan Cortex Radicis etc. 3. In the aggregation inhibition activating on the difference of density, GBH showed strong inhibition effect to the aggregation state induced to collagen, and it showed the inhibition effect in the individual consisting herbs as like Paeoniae Radix and Moutan Cortex Radicis about the aggregation induced by the collagen. 4. It showed the strong inhibition effect about the aggregation induced by the collagen in Paeoniae Radix Hoelen, Paeoniae Radix Moutan Cortex Radicis, Hoelen Moutan Cortex Radicis etc Like this, as confirm GBH and the individual consisting herb's inhibition effect of platelet aggregation, We considerated that GBH and the individual consisting herbs have practical applicational value of clinical trial in the thrombosis caused by platelet aggregation.

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Structures and Policies of British Geographic Information Dissemination for Korea National GIS Project (국가지리정보사업 추진을 위한 영국지리정보 유통구조 및 정책 연구 - 영국지리정보원의 역할을 중심으로-)

  • Kim, Bok-Hwan;Kim, Young-Hoon
    • Journal of the Korean Association of Geographic Information Studies
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    • v.9 no.4
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    • pp.22-33
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    • 2006
  • The objective of this paper is to discuss geographic information policies and strategies of British government and suggest effective policies for Korea National GIS project GIS that has been implemented geographic information infrastructures into public sectors and private markets for the last ten years. To obtain the research aim, this paper reviews the main factors of the Britain GIS project such as distribution structure and process of GI markets, government policies and strategies that are led by Ordnance Survey, most leading mapping agency in the UK. In conclusion, some issues have been explored with reference to the experiences of the Britain GIS projects. The first of these is the nature of geographic information and the second concerns the notion of the circulation policies of spatial data, and the last proposes Korea GIS policies and strategies for successful geographic information and spatial data implementation. The findings of the analysis of the Britain GIS development indicate that a shift began to take place from central government coordinate toward more extensive utilization of private and commercial sectors. This reflects both the increasing importance of geospatial data circulation in all levels of GIS stakeholders. Finally these discussions are particularly to be the issues where multi-agency collaboration of Korea government is concerned and can take the form of joint ventures by consortiums of both involving data producers and data users in order to increase commercial participation for value-added geospatial items, and to encourage both research and development sectors with low or free price policies.

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An Empirical Study on the Thermal Performance and Dynamic Behavior of Wall Integrated Thermosiphon Solar Water Heater (벽체일체형 자연순환 태양열온수기의 동적거동과 열성능에 관한 실증연구)

  • Baek, Nam-Choon;Kim, Sung-Bum;Shin, U-Cheul
    • Journal of the Korean Solar Energy Society
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    • v.36 no.6
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    • pp.25-35
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    • 2016
  • In this study, the evaluation of the dynamic behavior and thermal performance of the "Façade integrated Natural circulation Solar Water Heating System" installed in the residential house was carried out. Experimental tests were performed during the all year around in the rural houses of $166m^2$ in size. Facade integrated solar collector of $5m^2$ were installed on the south-facing. Electrical heater of 1 kW capacity as an auxiliary heater was installed at the upper part of the heat storage tank. The analyzing results are as follows. (1) Monthly average solar fraction was 51 to 87% and yearly average value is 64%. (2) Hot water supply temperature in December which has the lowest solar altitude is 37 to $76^{\circ}C$. The highest working fluid temperature of solar collector in this period was below $84^{\circ}C$. The temperature difference of working fluid between the collector inlet and outlet has been shown to be around 9 to $26^{\circ}C$. (3) Overheating which is one of the biggest problems during summer did not appear at all, but rather had hot water supply temperature is rather low as $30{\sim}47^{\circ}C$ in summer than winter, which is supplied by a small solar load. The solar collecting temperature has been shown to maintain below $55^{\circ}C$. (5) The thermal performance of Facade integrated solar collector can be increase due to the reduction of heat loss to the back of the collector wall integration of the collector is reduced. As a conclusion, Facade integrated natural circulation type Solar Water Heating System is a well-functioning without any pumps or controllers, and it was found that the disadvantages of conventional solar water heaters, hot water or hot water system can be greatly improved.

Experimental Studies on Extracorporeal Circulation by Rygg-Kyvsgaard Heart-Lung Machine, Hartman`s Solution Prime,and Moderate Hypothermia: [Part I] (Hartmann`s 용액으로 충진한 혈희석 체외순환에 관한 실험적 연구: (1보: 심폐기 Rygg-Kyvsgaard 의 혈산화와 혈압 및 혈액상에 미치는 영향))

  • 지행옥
    • Journal of Chest Surgery
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    • v.4 no.2
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    • pp.69-80
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    • 1971
  • Total body perfusion using Rygg-Kyvsgaard Heart-Lung-Machine, Mark IV, Polystan was attempted in the dogs by the hemodilution method with total prime of buffered Hartman's solution and under hypothermia. The first of all, the functions of Rygg--Kyvsgaard Heart-Lung-Machine and the effects of the hemodilution perfusion by buffered Hartman's solution was studied. At the same time the changes of blood pressure, oxygen consumption, and influence on the blood pictures were observed before, during, and in 1-3 days after perfusion. Hemodilution rates were the average 74. 22cc/Kg(the ranges of 67 to 81 cc/Kg) and perfusion flow rates were maintained in the mean 62. 6cc/Kg/min., Although it was possible to check up to 87 cc/ Kg/min. The total body perfusion continued for 60-80 minutes. Hypothermia was employed between $36^{\circ}C$ and $32^{\circ}C$ of the rectal temperature. Arterial pressure was ranged approximately between 68mmHg and 149mmHg, but generally, it was maintained over 80mmHg. Venous pressure was measured between 6.5cm $H_2O$and 11.5cm $H_2O$. Optimum oxygenation can be expected when oxygen flow into the disposable bubble oxygenator was maintained approximately at 3.5 L/min .. Inthis way, the oxygen contents were measured in the mean value of 13.11${\pm}$O.56 vol. % of arterial blood and 8.67+1.08 vol.% of venous blood(P${\pm}$0.86 vol.% in arteriovenous oxygen difference and 2. 97${\pm}$0.62cc/Kg in oxygen consumption were calculated. According to these dates, it is as plain as pikestaff that excellent oxygenation and good tissue perfusion was accomplished. Erythrocyte, hemoglobin and hematocrit were decreased about 38% during extracorporeal circulation and these were not recovered until 1-3 days after perfusion. These decrease was resulted from relatively high degree of hemodilution rate and no blood transfusion to compensate during these experimental studies. The platelets were also decreased about 76% during perfusion, but on the contrary, it was increased progressively after perfusion and in 1-3 days after perfusion was returned to the control level. Leucocyte were also decreased during perfusion, but it was increased progessively after perfusion and in 1-3 days after perfusion exceed the control level. This increase was resulted from postoperative infection of the wound, but its analysis were not changed significantly.

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Numerical Modeling of Circulation Characteristics in the Kwangyang Estuarine System (광양만 권역의 해수순환 수치모델 실험)

  • Kim, Baek Jin;Ro, Young Jae;Jung, Kwang Young;Park, Kwang Soon
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.26 no.4
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    • pp.253-266
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    • 2014
  • The ECOM3D is used to study the circulation characteristics and density current from the Sumjin River runoff in the Kwangyang Estuarine System, South Sea, Korea. Annual mean value of $120m^3/s$ was imposed from the Sumjin River. The numerical model results in terms of tidal height, current and salinity field show satisfactory with skill scores over 90%. The current velocity showed the range of 1~2.5 m/s during flood and ebb phases. In particular, very strong flow occur in the narrow Channels of Noryang, Daebang and Changson exceeding over 2.0 m/s. The tidal residual currents in the various locations in the Kwangyang Estuary showed the range of 1~21 cm/s, The density-driven current through the Yeosu and Noryang Channels are about 12 cm/s and 4 cm/s, respectively. The current path through the Yeosu Channel is deflected toward west Bank. Based on budget analysis of the volume flux, the volume flux through the Yeosu Channel and the Noryang Channel were estimated to be 97.4 and $22.1m^3/s$ accounting for the 81.5% and 18.5% of total flux, respectively.

A Model on a Bubbling Fluidized Bed Process for CO2 Capture from Flue Gas (연소기체로부터 CO2를 포집하는 기포 유동층 공정에 관한 모델)

  • Choi, Jeong-Hoo;Youn, Pil-Sang;Kim, Ki-Chan;Yi, Chang-Keun;Jo, Sung-Ho;Ryu, Ho-Jung;Park, Young-Cheol
    • Korean Chemical Engineering Research
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    • v.50 no.3
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    • pp.516-521
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    • 2012
  • This study developed a simple model to investigate effects of important operating parameters on performance of a bubbling-bed adsorber and regenerator system collecting $CO_2$ from flue gas. The chemical reaction rate was used with mean particles residence time of a reactor to determine the extent of conversion in both adsorber and regenerator reactors. Effects of process parameters - temperature, gas velocity, solid circulation rate, moisture content of feed gas - on $CO_2$ capture efficiency were investigated in a laboratory scale process. The $CO_2$ capture efficiency decreased with increasing temperature or gas velocity of the adsorber. However, it increased with increasing the moisture content of the flue gas or the regenerator temperature. The calculated $CO_2$ capture efficiency agreed to the measured value reasonably well. However the present model did not agree well to the effect of the solid circulation rate on $CO_2$ capture efficiency. Better understanding on contact efficiency between gas and particles was needed to interpret the effect properly.

A Strategic Study of Pedestrian-Friendly Reconstruction in University Campus Core - Case Study of 'H' University in Gyeonggi-do Province - (대학 캠퍼스코어의 보행친화형 개조전략 연구 - 경기도 H대학교를 사례로 -)

  • Hong, Youn-Soon;Park, Chung-In
    • Journal of the Korean Institute of Landscape Architecture
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    • v.42 no.6
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    • pp.89-100
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    • 2014
  • The Campus Core is centered at the physical, functional and symbolic environment of a university, which is known as the top academic institution, hence it metaphorically represents not only the educational philosophy when institution first opened, but also the transformed values of the time. Today, universities are asked to actively communicate with the local community in terms of function and be remodeled as pedestrian-friendly campuses in terms of physical environment. For this reason, the study comprehends the concept of the campus core in accordance with a pedestrian-friendly environment and suggests a practical plan for campus cores of district national universities based on previous research examination. Since the purpose of the study is to suggest a change in the circulation system centered on vehicle use to transform into a pedestrian-friendly environment through a planned approach while introducing public mixed-use at the same time, the study supports the fact that it is possible to reorganize the strategy of a pedestrian-friendly circulation system and partially revise the land utilization to yield the expected outcomes. Thus, this study will provide valid suggestions for similar maintenance plans while looking back to the meaning and value of today's campus core.

Preliminary Design of a Urban Transit Passenger Guidance System Using Congestion Management Model (혼잡관리 모형을 이용한 도시철도 이용객 동선유도시스템 기본설계)

  • Kim, Kwang-Mo;Park, Hee-Won;Kim, Jin-Ho;Park, Yong-Gul
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.5
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    • pp.3610-3618
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    • 2015
  • The congestion of railway vehicle and station shows up to 220%. Especially, transfer resistance of passenger increase rapidly by the collision of circulation. So increment of travel time, occurrence of safety accidents act as a factor that inhibits the utilization of urban railway station. In this paper, to improve traveling speed and comfort of urban rail passengers, urban transit passenger guidance system using congestion management model is proposed. The congestion management model that can mitigate a recurring/non-recurring congestion is constructed and the preliminary design of the system (middleware system, control system, guidance drive system) is carried out. Passenger Guidance System is configured by step for changing the external data into a form usable by the algorithm, step to perform the congestion management algorithm using the real-time data and historical data, step to control device based on the value that is calculated by congestion management algorithm, step to drive the device based on the information in the control system and circulation guidance devices. In the future, detail design will be performed based on the preliminary design. A prototype of the various devices according to the station structures and locations will be made. The control module of guidance device will be developed.

Failure Mode and Effect Analysis for Remanufacturing of the Old Extrusion Press (노후 압출기의 재제조를 위한 고장모드 영향분석)

  • Jung, Hang-Chul;Yun, Sang-Min;Oh, Sang-Ho;Baeg, Chang Hyun;Kong, Man-Sik
    • Clean Technology
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    • v.27 no.4
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    • pp.297-305
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    • 2021
  • In the domestic aluminum industry, the extrusion process is a major process accounting for more than 40% of the total production. However, most domestic aluminum extrusion companies produce aluminum using old equipment that is more than 30 years old. Extrusion press is when the equipment is not replaced before the wear and breakage of major parts occur, reducing productivity and increasing the defect rate compared to new equipment. The old extrusion press often loses part drawings, so it is difficult to repair them properly on-site and to remanufacture them due to the lack of technical skills for maintenance. Therefore, a systematic remanufacturing plan must be designed from dismantling the equipment. In this study, remanufacturing FMEA was devised to remanufacture old extrusion press. The risk priority was analyzed by considering the degree of damage to the recycled parts, the cycle due to breakage/damage during the extrusion process, and the value of recycling resources due to remanufacturing. To standardize the remanufacturing process, remanufactured FMEA was performed through part analysis according to the structural analysis of the extrusion press. In addition, remanufacturing priorities were selected for each part, while remanufacturing itself was studied for efficiency of resource circulation and product quality stabilization.

Key Elements for Standardizing the Estimation of Greenhouse Gas Emissions Reduction Induced by Remanufactured Products (재제조품의 온실가스배출 저감효과 산정 표준화를 위한 핵심 요소 도출)

  • Nam Seok Kim;Kook Pyo Pae;Jae Hak No;Hong-Yoon Kang;Yong Woo Hwang
    • Resources Recycling
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    • v.33 no.2
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    • pp.62-72
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    • 2024
  • Although the Paris Agreement in 2015 aimed to limit global temperature increases to below 2℃ and eventually to 1.5℃ to address the climate crisis, global temperature continues to rise. Developed countries have proposed a circular economy as a major strategy to tackle this issue. Detailed implementation methods include reusing, remanufacturing, recycling, and energy recovery. Remanufacturing has a greater potential to achieve high added value and carbon neutrality than other resource circulation methods. However, currently, no standardized method for quantitatively evaluating the greenhouse gas (GHG) reduction effects of remanufacturing exists. This study compares and analyzes recent research trends since 2020 on the calculation of GHG emission reduction effects from remanufacturing. It also examines international standards for environmental impact assessment, including GHGs and environmental performance labeling systems. This study derives the key factors for standardizing the calculation of the GHG emission reduction effects of remanufactured products.