• Language and Information
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• v.14 no.2
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• pp.71-84
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• 2010

The aim of this paper is to propose that a category P is encapsulated within a functional layer above the lexical layer, just like vP containing a lexical VP. As is well known, the category P has long been in the obscure domain of syntactic studies: Marantz (2001) and den Dikken (2003), for example, argue that P is a lexical category, but Emonds (1985), Grimshaw (1991), and Baker (2003), maintain that the category P is functional and is a closed category without its own intrinsic meaning. On the other hand, Zwart (2005) argues that it does have some meaning. Following the works of Svenonius (2003, 2006, 2007), and the spirit of Rizzi's (1997) split CP hypothesis, we elaborate and develop Svenonius' idea of split-pP analysis with detailed schematic representations of the novel examples in English, Korean, and Chinese in this paper. Unlike Svenonius, however, this paper incorporates KP into pP-Shell, which is a substantial simplification. Furthermore, Chinese Localizers that have long been considered as Postpositions are now under the category of Prepositions. This proposal renders an X-bar theoretic consistency over the categorical status of Chinese phrasal structures. In short, the present analysis accounts for inconsistency found in English complex preposition phrase (Quirk, et al, 1972, 1985), Chinese circumposition phrase (Ernst 1988, Liu, 2002) and Korean postposition phrase in a unified and consistent manner. Furthermore, by proposing a finer-grained phrasal architecture for the category P, the controversial status of the category subsides within this analysis.

• Earthquakes and Structures
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• v.11 no.6
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• pp.1001-1025
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• 2016

Building structures generally have inherent low damping capability and hence are vulnerable to seismic excitations. Control devices therefore play a useful role in providing safety to building structures subject to seismic events. In recent years semi-active dampers have gained considerable attention as structural control devices in the building construction industry. Magneto-rheological (MR) damper, a type of semi-active damper has proven to be effective in seismic mitigation of building structures. MR dampers contain a controllable MR fluid whose rheological properties vary rapidly with the applied magnetic field. Although some research has been carried out on the use of MR dampers in building structures, optimal design of MR damper and combined use of MR and passive dampers for real scale buildings has hardly been investigated. This paper investigates the use of MR dampers and incorporating MR-passive damper combinations in building structures in order to achieve acceptable levels of seismic performance. In order to do so, it first develops the MR damper model by integrating control algorithms commonly used in MR damper modelling. The developed MR damper is then integrated in to the seismically excited structure as a time domain function. Linear and nonlinear structure models are evaluated in real time scenarios. Analyses are conducted to investigate the influence of location and number of devices on the seismic performance of the building structure. The findings of this paper provide information towards the design and construction of earthquake safe buildings with optimally employed MR dampers and MR-passive damper combinations.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.25 no.7
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• pp.1064-1072
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• 2001

It is very important to evaluate material degradation like temper and carbide embrittlements to secure the reliable and efficient operational conditions and to prevent brittle failure in service. The extent of material deterioration can be accurately evaluated by mechanical test such as impact test or creep test. But it is almost impossible to sample a large specimen from in-service plants. Thus, the material degradation evaluation by a non-destructive method is earnestly required. Recently the non-destructive test technique which uses the grain boundary etching characteristics owing to the variation of material structures has been proposed. However the program for material degradation evaluation using the grain boundary etching method(GEM) in Windows 98 domain doesnt be developed now. The aims of this paper are to develop the program and to complete the new master curve equations for the evaluation of material degradation on in-serviced high temperature components.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.3
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• pp.1011-1018
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• 2015

This study was conducted to investigate the plasma phosphoproteome and differential plasma phosphoproteins in cases of of Opisthorchis viverrini (OV)-related cholangiocarcinoma (CCA). Plasma phosphoproteomes from CCA patients (10) and non-CCA subjects (5 each for healthy subjects and OV infection) were investigated using gel-based and solution-based LC-MS/MS. Phosphoproteins in plasma samples were enriched and analyzed by LC-MS/MS. STRAP, PANTHER, iPath, and MeV programs were applied for the identification of their functions, signaling and metabolic pathways; and for the discrimination of potential biomarkers in CCA patients and non-CCA subjects, respectively. A total of 90 and 60 plasma phosphoproteins were identified by gel-based and solution-based LC-MS/MS, respectively. Most of the phosphoproteins were cytosol proteins which play roles in several cellular processes, signaling pathways, and metabolic pathways (STRAP, PANTHER, and iPath analysis). The absence of serine/arginine repetitive matrix protein 3 (A6NNA2), tubulin tyrosine ligase-like family, member 6, and biorientation of chromosomes in cell division protein 1-like (Q8NFC6) in plasma phosphoprotein were identified as potential biomarkers for the differentiation of healthy subjects from patients with CCA and OV infection. To differentiate CCA from OV infection, the absence of both serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform and coiled-coil domain-containing protein 126 precursor (Q96EE4) were then applied. A combination of 5 phosphoproteins may new alternative choices for CCA diagnosis.

• The Journal of the Acoustical Society of Korea
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• v.13 no.1
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• pp.71-83
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• 1994

This paper deals with the improvement of the synthesized speech quality and naturality in the Korean TTS(Text-to-Speech) system. We had extracted the parameters(table2) such as its amplitude, duration and pitch period in a syllable through the analysis of speech waveforms(table1) in the time domain and synthesized syllables using them. To the frequencies of the Korean pronunciation large vocabulary dictionary we had synthesized speeches selected 229 syllables such as V types are 19, CV types are 80. VC types are 30 and CVC types are 100. According to the 4 Korean syllable types from the data format dictionary(table3) we had tested each 15 syllables with the objective MOS(Mean Opinion Score) evaluation method about the 4 items i.e., intelligibility, clearness, loudness, and naturality after selecting random group without the knowledge of them. As the results of experiments the qualities of them are very clear and we can control the prosodic elements such as durations, accents and pitch periods (fig9, 10, 11, 12).

• Journal of KIISE:Computing Practices and Letters
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• v.9 no.5
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• pp.578-587
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• 2003

The DSTM (Dual Stack Transition Mechanism), one of tunneling mechanism, is considered as the best solution in IPv4/IPv6 transition recently. The DSTM provides a method to assure IPv4/v6 connectivity based on 4over6 (IPv4-over-IPv6) tunneling and temporal allocation of a global IPv4 address to a host requiring such communication. A TEP (Tunnel End Point) operates as a border router between IPv6 domain and IPv4 Internet, which performs encapsulation and decapsulation of 4over6 tunneling packets to assure hi-directional forwarding between both networks. In this paper, we analyze basic standards of the IPv6 protocol. And, we design and implement a DSTM TEP daemon block. The TEP daemon analyzes a fevers tunneling packet that is forwarded by the DSTM node, establishes the TEP's 4over6 interface, and supplies communication between a DSTM and a IPv4-only node. Finally, we construct a DSTM testbed and measure performance of the DSTM TEP. Our observation results show that performance of TEP supports the DSTM service.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.12
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• pp.475-481
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• 2019

The importance of performance-based design feedback is being emphasized when it comes to the potential impact that affects all the lifecycle of the building. However, the latency and disconnection of domain expert in the sector of AEC/FM remain current obstacles between design and performance feedback. It is hard to utilize performance feedback information for design exploration and support design decision making during the conceptual phase of design. Using parametric design, this paper proposes various design alternatives from a set of rules and constraints defined by algorithms for the geometric configurations of an Office Building. A Building Performance Analysis (BPA) was to developed using Autodesk® Revit® 2019 which integrates Autodesk® Green Building Studio® to predict its sufficient daylighting conditions of the LEED v4's Daylighting Autonomy (DA). The parametric-based performance feedback of this study outlines potential design improvements for further exploration in application to the early design process.

• Journal of Microbiology and Biotechnology
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• v.18 no.1
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• pp.43-47
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• 2008

The nickel and cobalt resistance of Cupriavidus metallidurans CH34 is mediated by the CnrCBA efflux pump encoded by the cnrYHXCBAT metal resistance determinant. The products of the three genes cnrYXH transcriptionally regulate expression of cnr. CnrY and CnrX are membrane-bound proteins, probably functioning as anti-sigma factors, whereas CnrH is a cnr-specific extracytoplasmic functions (ECF) sigma factor. The periplasmic domain of CnrX (residues 29-148) was cloned as a N-terminal His-tagged protein, expressed in Escherichia coli, and purified using affinity chromatography and gel filtration. The molecular mass was estimated to be about 13.6kDa by size exclusion chromatography, corresponding to a monomer. The tetragonal bipyramid crystals were obtained by mixing an equal volume of protein in 50mM Tris-HCl, pH 7.5, 1% glycerol, 100mM NaCl, 1mM DTT, and the reservoir solution of 15% w/v PEG 2000, 100mM lithium chloride at 277K in 2-4 days using hanging drop vapor diffusion. The protein concentration was 24mg/ml. The crystal that diffracted to $2.42{\AA}$ resolution belongs to space group $P4_1\;or\;P4_3$ with unit cell parameters of $a=b=32.14{\AA},\;c=195.31{\AA},\;{\alpha}={\beta}={\gamma}=90^{\circ}$, with one molecule of CnrX in the asymmetric unit.

• Clinical and Experimental Pediatrics
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• v.60 no.6
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• pp.167-174
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• 2017

Mycoplasma pneumoniae pneumonia (MPP) is one of the most common forms of community-acquired pneumonia in children and adolescents. Outbreaks of MPP occur in 3- to 7-year cycles worldwide; recent epidemics in Korea occurred in 2006-2007, 2011, and 2015-2016. Although MPP is known to be a mild, self-limiting disease with a good response to macrolides, it can also progress into a severe and fulminant disease. Notably, since 2000, the prevalence of macrolide-resistant MPP has rapidly increased, especially in Asian countries, recently reaching up to 80%-90%. Macrolide-resistant Mycoplasma pneumoniae (MRMP) harbors a point mutation in domain V of 23S rRNA with substitutions mainly detected at positions 2063 and 2064 of the sequence. The excessive use of macrolides may contribute to these mutations. MRMP can lead to clinically refractory pneumonia, showing no clinical or radiological response to macrolides, and can progress to severe and complicated pneumonia. Refractory MPP is characterized by an excessive immune response against the pathogen as well as direct injury caused by an increasing bacterial load. A change of antibiotics is recommended to reduce the bacterial load. Tetracyclines or quinolones can be alternatives for treating MRMP. Otherwise, corticosteroid or intravenous immunoglobulin can be added to the treatment regimen as immunomodulators to downregulate an excessive host immune reaction and alleviate immune-mediated pulmonary injury. However, the exact starting time point, dose, or duration of immunomodulators has not been established. This review focuses on the mechanism of resistance acquisition and treatment options for MRMP pneumonia.

• Journal of Microbiology
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• v.44 no.4
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• pp.447-452
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• 2006

The murine ecotropic retroviral receptor has been demonstrated to function as a mouse cationic amino acid transporter 1(mCAT1), and is comprised of multiple membranespanning domains. Feral mouse (Mus dunni) cells are not susceptible to infection by the ecotropic Moloney murine leukemia virus (MoMLV), although they can be infected by other ecotropic murine leukemia viruses, including Friend MLV and Rauscher MLV. The relative inability of MoMLV to replicate in M. dunni cells has been attributed to two amino acids $(V_{214}\;and\;G_{236})$ located within the third extracellular loop of the M. dunni CAT1 receptor (dCAT1). Via the exchange of the third extracellular loop of the mCAT1 cDNA encoding receptor from the permissive mouse and the corresponding portion of cDNA encoding for the nonpermissive M. dunni receptor, we have identified the most critical amino acid residue, which is a glycine located at position 236 within the third extracellular loop of dCAT1. We also attempted to determine the role of the third extracellular loop of the M. dunni CAT1 receptor with regard to the formation of the syncytium. The relationship between dCAT1 and virus-induced syncytia was suggested initially by our previous identification of two MLV isolates (S82F in Moloney and S84A in Friend MLV), both of which are uniquely cytopathic in M. dunni cells. In an attempt to determine the relationship existing between dCAT1 and the virally-induced syncytia, we infected 293-dCAT1 or chimeric dCAT1 cells with the S82F pseudotype virus. The S82F pseudotype virus did not induce the formation of syncytia, but did show increased susceptibility to 293 cells expressing dCATl. The results of our study indicate that S82F-induced syncytium formation may be the result of cell-cell fusion, but not virus-cell fusion.