• Journal of Preventive Medicine and Public Health
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• 제40권4호
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• pp.297-304
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• 2007

Objectives : We investigated the validity of the dipstick method (Mossman Associates Inc. USA) and the expired CO method to distinguish between smokers and non-smokers. We also elucidated the related factors of the two methods. Methods : This study included 244 smokers and 50 ex-smokers, recruited from smoking cessation clinics at 4 local public health centers, who had quit for over 4 weeks. We calculated the sensitivity, specificity and Kappa coefficient of each method for validity. We obtained ROC curve, predictive value and agreement to determine the cutoff of expired air CO method. Finally, we elucidated the related factors and compared their effect powers using the standardized regression coefficient. Results : The dipstick method showed a sensitivity of 92.6%, specificity of 96.0% and Kappa coefficient of 0.79. The best cutoff value to distinguish smokers was 5-6ppm. At 5 ppm, the expired CO method showed a sensitivity of 94.3%, specificity of 82.0% and Kappa coefficient of 0.73. And at 6 ppm, sensitivity, specificity and Kappa coefficient were 88.5%, 86.0% and 0.64, respectively. Therefore, the dipstick method had higher sensitivity and specificity than the expired CO method. The dipstick and expired CO methods were significantly increased with increasing smoking amount. With longer time since the last smoking, expired CO showed a rapid decrease after 4 hours, whereas the dipstick method showed relatively stable levels for more than 4 hours. Conclusions : The dipstick and expired CO methods were both good indicators for assessing smoking status. However, the former showed higher sensitivity and specificity and stable levels over longer hours after smoking, compared to the expired CO method.

• 한국콘텐츠학회논문지
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• 제19권10호
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• pp.442-451
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• 2019

본 연구는 캠퍼스 금연 교육 프로그램에 참여하고 금연에 성공한 대학생들의 장기금연 효과를 파악하기 위하여 실시되었다. 연구 대상자들은 2016년부터 2018년까지 서울시 소재 일개 대학에서 36주에 걸쳐 진행되는 캠퍼스 금연 교육 프로그램의 2차 자료와 참여 후 금연에 성공한 전체 금연성공자중, 연구에 참여하기로 동의한 30명이었다. 캠퍼스내에서의 흡연이 전면 금지되어 있는 서울시내 일개 대학교의 금연 교육 프로그램은 금연관련 교육과 상담, 주1회 소변 내 Cotinine 검사, 금연장학금 지급으로 구성되었다. 참여자의 평균 금연 성공률은 1차시 50.17%, 2차시 44.16%, 3차시 77.30%로 나타났으며, 2차 성공이후에 금연이 고착화되는 경향이 관찰되었다. 본 연구에서 금연에 성공한 이후, 12개월 이상 금연을 유지하고 있는 참여자는 51.22%, 흡연 재발한 참여자는 무응답 흡연자를 포함하여 48.78%이었다. 금연유지의 가장 큰 성공요인은 금연의지(28.57%)였으며, 금연유지의 가장 큰 실패요인은 스트레스(66.67%)로 나타났다 대학생을 위한 캠퍼스 주도적 금연 교육 프로그램은 대학생 흡연자의 금연유도 뿐 아니라 금연을 습관화하여 장기금연 유지자로 전환시키는데 효과적인 프로그램임을 확인할 수 있었다.

• 한국환경보건학회지
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• 제47권3호
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• pp.227-244
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• 2021

Objectives: The Korean National Environmental Health Survey provides representative biomonitoring data for environmental pollutants in South Korea. Over the last decade, there have been various studies published using this data. In this study, we aimed to provide information and implications by reviewing each study. Methods: We searched comprehensive electronic databases from PubMed, Google Scholar, and Naver Academic database using the key words 'Korean National Environmental Health Survey' and 'KoNEHS' through March 2021. A total of 57 studies were selected after reviewing the relevance of the data. Results: The most frequently studied pollutants were heavy metals (10), Cotinine (8), Bisphenol A (7), and Phthalates (6), in that order. In particular, Phthalates, Bisphenol A, and Parabens were often studied together (6). A decline in urinary cotinine and heavy metals in the body was shown over time among studies on exposure association. It was demonstrated that Phthalates and Bisphenol A were significantly related to obesity and diabetes from the studies of health impacts. Cross-section study design, spot urine, and insufficient health status information were mostly reported as limitations of the data. Conclusion: Since research has been focused on adults, further investigations of children and adolescents are required. In this regard, it is necessary to maintain the consistency of the data structure and provide integrated weights for all ages. In addition, it would allow the measurement of several environmental pollutants by considering subsample design. Lastly, integrated studies with multi-cycles and the health effects from co-exposure to multiple chemicals would be expected to provide important knowledge.

• 한국환경보건학회지
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• 제48권2호
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• pp.96-105
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• 2022

Background: Pyrethroid insecticides account for more than 30% of the global insecticide market and are frequently used in agricultural settings and residential and public pest control among the general population. While several animal studies have suggested that exposure to pyrethroids can alter glucose homeostasis, there is only limited evidence of the association between environmental pyrethroid exposure and diabetes in humans. Objectives: This study aimed to report environmental 3-phenoxybenzoic acid (3-PBA) concentrations in urine and evaluate its association with the risk of diabetes in Korean adults. Methods: We analyzed data from the Korean National Environmental Health Survey (KoNEHS) Cycle 2 (2012~2014) and Cycle 3 (2015~2017). A total of 10,123 participants aged ≥19 years were included. Multiple logistic regressions were used to calculate the odds ratios (ORs) for diabetes according to log-transformed urinary 3-PBA levels. We also evaluated age, sex, education, monthly income, marital status, alcohol drinking, physical activity, urinary cotinine, body mass index, and sampling season as potential effect modifiers of these associations. Results: After adjusting for all the covariates, we found significant dose-response relationships between urinary 3-PBA as quartile and the prevalence of diabetes in pooled data of KoNEHS Cycles 2 and 3. In subgroup analyses, the adverse effects of pyrethroid exposure on diabetes were significantly stronger among those aged 19~39 years (p-interaction<0.001) and those who consumed high levels of cotinine (p-interaction=0.020). Conclusions: Our findings highlight the potential diabetes risk of environmental exposure to pyrethroids and should be confirmed in large prospective studies in different populations in the future.

• 한국식품과학회지
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• 제35권5호
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• pp.980-987
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• 2003

삼백초 및 포공령, 흑두, 금은화, 결명자, 감초 추출은 혼합물(Oriental herb extracts mixture, OHEM) 의 해독효과를 확인하고자 nicotine 및 dioxin에 대한 급성독성시험을 하였다. 치사량(42mg/kg)의 nicotine을 ICR mouse에 복강주사 하였을 때 OHEM 투여군은 대조군에 비해 마비 개시시간이 2배 이상 지연되었으며, 발작 지속 시간은 1/2로 감소하였고 생존율은 73%로 나타나 해독효과가 강한 것으로 밝혀졌다. 인체를 대상으로 nicotine분해 물질인 뇨중 cotinine배설량을 측정한 결과 OHEM의 섭취가 혈 중 nicotine 분해를 촉진시켜 초기 뇨 중 cotinine 배설량을 1.5배까지 증가시킨 후 뇨중 continine 함량을 OHEM 섭취전의 5% 이하로 감소시켰다. TCDD로 급성특성을 유도한 rat 혈액의 임상 화학적 지수에 hemoglobin의 경우 OHEM의 섭취가 TCDD 투여에 따른 감소를 완화시키는 것으로 나타났으며, 혈소판의 경우 TCDD에 의한 감소를 OHEM 투여가 정상수준으로 회복시켰다(p<0.05) Neutrophil seg(%) 및 monocyte(%)은 TCDD 투여로 감소하였으나 OHEM의 투여로 정상수준으로 회복되었다, 알부민 함량은 TCDD 투여에 의해 감소(p<0.05) 하였으나, OHEM투여로 정상 수치로 회복하였으며 또한, GOT 및 GPT활성 역시 TCDD 투여로 증가하였으나. OHEM 투여로 활성을 저하시키는 것으로 나타났다. 총콜레스테롤 및 혈중 중성지질 함량은 TCDD 투여군 모두 유의적으로 증가 하였으며, OHEM의 투여가 TCDD에 의한 총 콜레스테롤 및 중성지질 수준을 유의차 있게 회복시켰다(p<0.05). 신장 기능에 관련된 creatinine은 OHEM 투여에 의해 TCDD에 의한 증가를 억제하였으며 철 함량은 TCDD 투여로 유의차 있게 감소하였으나 OHEM 투여로 정상 수준으로 회복되었다 TCDD 투여는 혈액과 췌장에 대한 독성작용이 간, 신장 및 심장에 대만 작용에 비해 훨씬 강하게 나타났으며, OHEM에 의한 독성 경감작용은 간 및 췌장에서 효과적으로 나타났다. OHEM의 투여가 TCDD에 의한 임상 지수의 변화를 정상수지에 가깝게 회복 시키는 것으로 나타나 체내대사 및 기능장애를 일부 회복시키는 물질임을 확인할 수 있었다.

• 대한간호학회지
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• 제38권2호
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• pp.204-216
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• 2008

Purpose: Meta-analysis of this study was to analyze the character of adolescent smoking cessation programs, to calculate the effect size according to variables and to compare the weighted mean effect sizes on adolescent smoking cessation programs in Korea. Methods: Twenty two studies for meta-analysis were selected from dissertations, theses, articles and research papers that had been published from 1995 to 2003. The selected studies had a randomized or nonequivalent control group in a pretest-post test design and had reported statistical value to calculate the effect size. Results: The mean number of sessions was 6.5. The education time per each session varied from 40 to 150 min and the most applied theories were Bandura's social-cognitive theory and the cognitive-behavioral theory. Smoking-knowledge, smoking-attitudes and smoking-amount showed high effects on the first post test after mediating adolescent smoking cessation programs according to the criteria of Cohen. The effect size of urine-cotinine found no homogeneity on the first post test, but it was significantly effective on the second post test. Conclusion: Adolescent smoking cessation programs analyzed in this study were relatively effective in smoking abstinence.

• 대한간호학회지
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• 제45권3호
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• pp.347-356
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• 2015

Purpose: In this study, the effectiveness of a motivational interviewing smoking cessation YOU-TURN program for adolescents was examined. The program was based on the self-determination theory. Methods: The study was carried out with a nonequivalent control group pretest-posttest design. Participants in the present study were 136 high school students living in D city. The students were assigned to the experimental group (n=52) who participated in the motivational interviewing smoking cessation YOU-TURN program based on self-determination theory, or to the control group (n=84) who participated in a general smoking cessation program. Data were collected from September 1, 2013 through April 30, 2014. Collected data were analyzed using SPSS PC+ 21.0 with Chi-square test, Fisher's exact test, t-test, Mann-Whitney U test, Repeated Measures ANOVA, and MANOVA-Wilk's Lambda. Results: The experimental group had a significant increase in basic psychological needs, and duration of quitting-smoking in comparison with the control group. The experimental group had a significant decrease in cigarettes smoked per day and cotinine in urine in comparison with the control group. Conclusion: The motivational interviewing YOU-TURN program, when delivered to adolescents who smoked, was effective in discouraging smoking, and can be utilized as an effective nursing intervention for adolescents who smoke.

• 대한간호학회지
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• 제47권2호
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• pp.164-177
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• 2017

Purpose: This study was done to develop a strength based I-change smoking cessation program for middle school boys and identified its effects. Methods: The study design was a nonequivalent control group pre-post test design. The participants were 97 middle school students from D city, who were in school from April 6 to September 25, 2015. The experimental group participated in the strength based I-change smoking cessation program, while the comparative group participated in a general smoking cessation program. The control group did not participate in any program. Data analyses involved $x^2$-test, Fishers' exact test, Bonferroni test, and Repeated measures ANOVA, with the IBM SPSS for Windows (version 20.0) program. Results: Compared to the comparison and control groups, the experimental group showed significant improvement in knowledge, attitude, self-efficacy, behavior change. Also cotinine in urine and modeling of social influence in the experimental group significantly decreased after the strength based I-change smoking cessation program. Conclusion: These findings indicate that the strength based I-change smoking cessation program is an effective intervention for middle school boys who smoke. The findings suggest that such programs can be used at public health centers or through school health education to decrease smoking in adolescents.

• 보건교육건강증진학회지
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• 제24권4호
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• pp.115-130
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• 2007

Purpose: The Purpose of this study was to investigate the effects of the '5&6 smoking cessation program - six classes in five weeks' on the high school students' perception and smoking behavior. Methods: The data collection was done from November to December, 2006. This study was designed using nonequivalent control group pretest - posttest. Experimental group had 24 students, control group had 41 students. The '5&6 smoking cessation program' was applied to the experimental group for two hours per session during five weeks. Data analysis was done using descriptive statistics, X2-test, Fisher's exact test, Independent-samples t-test, Paired t-test, Cronbach's coefficient alpha. Results: The experimental group showed significant increase on smoking self-efficacy, stage of smoking cessation behavior change and significant decrease on daily smoking amount, dependancy of nicotine, urine cotinine level than control group. But the experimental group was not significantly changed at self-awareness, Pros. for smoking and Cons. for smoking. Conclusion: In conclusion, the results of this study showed that the 5&6 smoking cessation program, which focuses on self-awareness, is effective in adolescent's smoking cessation behaviors.

• 지역사회간호학회지
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• 제16권4호
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• pp.478-487
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• 2005

Purpose: This study was to examine the achievement rate of smoking cessation, to identify obstacles to smoking cessation, and to find means to achieve the goal of smoking cessation in college smokers. Method: This study was conducted from April 26th to September 13th 2004 and used a one-shot design. The subjects selected by convenient sampling were 29 college smokers who smoked over one cigarette a day, had a positive level of urine cotinine, participated in smoking cessation education 3 times. Thereafter, individual interaction was processed between the researcher and the subject using an interaction instrument. Data were analyzed based on frequencies.,percentages and means using SPSS/Win 10.0. Results: The achievement rate of smoking cessation was 20.7% (6 students). The biggest obstacles smoking cessation were smoking stimuli (29 students) and lack of control (25 students). Among detailed obstacles, the biggest one was smoking at regular times, which was followed by withdrawal symptoms, smoking on drinking, and company with other smokers. The most effective means of smoking cessation mentioned by the subjects were in order of avoiding drinking situations, taking deep breaths, and exercising. Conclusion: The results of this study, using King's theory, showed that individual interaction is effective in achieving smoking cessation. Therefore, it is suggested to make further study and broaden smoking cessation education for college smokers.