• Korean Journal of Health Education and Promotion
• /
• v.28 no.1
• /
• pp.49-56
• /
• 2011

Objectives: This study focuses on the effectiveness of a five-day target youth smoking cessation program in terms of smoking behavior, psychological characteristics, physiological changes, and 1-month maintenance of non-smoking. Methods: The participants in this one-group pre-posttest study were 91 youth smokers registered to a smoking cessation school at a hospital in Seoul. Data analyses performed include descriptive statistics, x2-test, paired t-test, and ANOVA. Results: A five-day smoking cessation program significantly decreased expired carbon monoxide level, stress, and depression. In post-intervention urine test, urine cotinine was detected in 14 of 91 participants(15.4%). In a one-month follow-up telephone survey 80.2% responded maintaining non-smoking. Conclusion: This study demonstrated the effect of a five-day smoking cessation program for adolescent smokers.

• Safety and Health at Work
• /
• v.9 no.1
• /
• pp.71-74
• /
• 2018

Background: Green tobacco sickness (GTS), an occupational disease in tobacco harvesters, is a form of acute nicotine intoxication by nicotine absorption through the skin from the wet green tobacco plant. We carried out a questionnaire survey and measured cotinine concentration, the metabolic product of nicotine, to determine the prevalence, incidence, and risk factors of GTS in Korean tobacco harvesters. Methods: We measured cotinine concentrations, and administered a questionnaire survey to tobacco harvesters in Cheongsong-gun, Gyeongsangbuk-do, Korea. We repeatedly measured urine cotinine concentration five times with a questionnaire survey. Results: Cotinine concentration at dawn was significantly higher than that at other times; it was significantly lower during the nonharvesting period than during the harvesting period. However, little change in cotinine concentration was detected in the daytime during the harvesting period. Study participants included 20 men and 20 women. The prevalence of GTS was 37.5% and was significantly higher in women than in men (55.0% vs. 20.0%, p < 0.01). GTS incidence according to number of workdays was 3.4 occurrences/100 person days. Conclusion: In this study, nicotine exposure and metabolism were experimentally determined from the time of cotinine exposure, and biological monitoring was performed in each season. In the future, this information may be valuable for medical decision-making in GTS prevention.

• Research in Community and Public Health Nursing
• /
• v.32 no.3
• /
• pp.268-280
• /
• 2021

Purpose: The study is examined the effects of the smoking cessation program of life skills training using flipped learning for male middle school students. Methods: The study was a nonequivalent control group non-synchronized design. The Smoking Cessation Program of life skills training using flipped learning is a Smoking Cessation Program that applied 5 stages of flipped learning such as before class, introductory class, during class, after class, and during work. Participants were 32 male students attending a middle school in D city, with 16 in the control group and 16 in the experiment group. Data collection was conducted from February 26, 2019 to May 14, 2019 for the control group, and from May 28, 2019 to August 19, 2019 for the experiment group. The collected smoking knowledge, smoking attitude, self-efficacy, basic psychological needs, and urine cotinine were analyzed by x² test, independent t-test, two-way repeated measured ANOVA, and Fishers exact test using the SPSS 25.0 program. Results: The experimental group showed higher smoking knowledge, smoking attitude, self-efficacy, basic psychological need, and urine cotinine negative response than the control group, and there were significant differences. Conclusion: These findings indicate that the Smoking Cessation Program of life skill training using flipped learning is an effective intervention for cessation of middle school male students, and it has a positive effect on the increase in urine cotinine, and a physiological indicator of the cessation effect, and is effective in the success of smoking cessation.

• Journal of Environmental Science International
• /
• v.28 no.3
• /
• pp.329-339
• /
• 2019

The National Institute of Environmental Research (3rd KONEHs) conducted a survey of 280 residents in Ulsan, Suwon and Asan, and the concentration of heavy metals in the blood and urine were also analyzed. In case of blood lead concentration, Ulsan $2.27{\mu}g/dl$, Suwon $2.08{\mu}g/dl$, and Asan $1.75{\mu}g/dl$, the high peak in Ulsan, and the low peak in Asan. In case of cotinine concentration, Ulsan smoking($609.16{\mu}g/g{\_}ct$) is higher than nonsmoking($74.07{\mu}g/g{\_}ct$), as Suwon and Asan smoking($416.72{\mu}g/g{\_}ct$, $903.21{\mu}g/g{\_}ct$) is higher than nonsmoking($72.72{\mu}g/g{\_}ct$, $18.06{\mu}g/g{\_}ct$), smoking group is higher than nonsmoking group in all areas revealed statistically significant correlation(p<0.01). In considering results synthetically, these study results are an aid to constructing environmental health science-side heavy metal management measure education programs for normal residents.

• Proceedings of the Korean Society of Toxicology Conference
• /
• 2002.11b
• /
• pp.173-173
• /
• 2002

This study was conducted to compare two biomarkers of environmental tobacco smoke (ETS); urinary cotinine and 1-hydroxypyrene-glucuronide (1-OHPG). Urine samples were collected from 102 junior high school students. Urinary cotinine was determined by GC and urinary 1-OHPG was assayed by synchronous fluorescence spectroscopy (SFS) after immuno-affinity purification using monoclonal antibody 8E11.(omitted)

• Journal of Preventive Medicine and Public Health
• /
• v.37 no.2
• /
• pp.127-132
• /
• 2004

Objectives : Cotinine, the major metabolite of nicotine, is a useful marker of exposure to tobacco smoke and self-reporting of smoking status is thought not to be reliable. This study aimed to evaluate the agreement between the smoking self-report among adolescents and the urinary cotinine test. Methods : The study subjects were 1226 middle and high school students in Hanam city, who were selected by stratified random sampling. The self-report about smoking behavior was compared with urine cotinine value measured with PBM $AccuSign^{\circledR}fi$ Nicotine(Princeton BioMeditech Corporation, USA). The percentage agreement, kappa and 95% confidence interval(CI) were calculated. Results : The overall percentage agreement was 88.6%, and those for boys, girls, middle school, general school and vocational school students were 87.3%, 90.1%, 93.7%, 85,5%, 90.7%, and 78.4%, respectively. The overall kappa index was 0.46(95% CI=0.39-0.54)for overall, .and those for boys, girls, middle school, general school and vocational school students were 0.56(95% CI=0.48-0.65), 0.20(95% CI=0.07-0.32), 0.21(95% CI=0.09-0.34), 0.55(95% CI=0.47-0.64), 0.42(95% CI=0.33-0.52), and 0.48(95% CI=0.36-0.60), respectively. Conclusion : The percentage agreement was relatively high but the kappa values very low for girls, and middle school students. Though the prevalence bias can be influenced by these results, the self-report was not a sufficient tool for the evaluation of adolescents' smoking status, especially in girls or middle school students.

• Journal of Environmental Health Sciences
• /
• v.35 no.2
• /
• pp.100-115
• /
• 2009

Secondhand smoke (SHS) is one of major public health threats. Since secondhand smoke is complex mixture of toxic chemicals, there has been no standardized method to measure SHS quantitatively. The purpose of this manuscript was to review various quantitative methods to measure SHS. There are two different methods: air monitoring and biological monitoring. Air monitoring methods include exhaled carbon monoxide level, ambient fine particulates, nicotine and 3-ethenylpyridine. Measurement of fine particulates has been utilized due to presence of real-time monitor, while fine particulates can have multiple indoor sources other than SHS. Ambient nicotine and 3-EP are more specific to SHS, although there is no real-time monitor for these chemicals. Biological monitoring methods include nicotine in hair, cotinine in urine, NNK in urine and DNA adducts. Nicotine in hair can provide chronic internal dose, while cotinine in urine can provide acute dose. Since biological monitoring can provide total internal dose, identification of specific exposure source may be difficult. NNK in urine can indicate carcinogenicity of the SHS exposure. DNA adducts can provide overall cancer causing exposure, but not specific to SHS. While there are many quantitative methods to measure SHS, selection of appropriate method should be based on purposes of assessment. Application of accurate and appropriate exposure assessment method is important for understanding health effects and establishing appropriate control measures.

• Environmental Analysis Health and Toxicology
• /
• v.19 no.2
• /
• pp.169-176
• /
• 2004

ETS (environmental tobacco smoke) is composed of exhaled mainstream smoke (MS) from the smoker, sidestream smoke (SS) emitted from the smoldering tobacco between puffs and contaminants that diffuse through the cigarette paper and mouth between puffs. These emissions contain both vapor phase and particulate contaminants. ETS is a complex mix of over 4,000 compounds. This mix contains many known or suspected human carcinogens and other toxic agents. More of these toxic compounds are found in SS than in MS. Workplace exposure to ETS can result in significant smoke intake, and passive smoke exposure may be related to impair respiratory function and an increase risk of lung cancer in nonsmokers. For nonsmokers sharing a work environment with cigarette smokers, the workplace must be considered hazardous independently of any specific industrial toxic exposure. The risk is particularly important when a high percentage of the workers smoke or where smokers and nonsmokers work in poorly ventilated areas. Nicotine is converted in the body to cotinine; cotinine therefore can be used as an indirect measure of a person's recent exposure to tobacco smoke. Levels of nicotine in hair and levels of cotinine in body fluids (saliva and urine) have been shown to increase with increasing environmental nicotine levels and with self-reported ETS exposure. The measurement of nicotine or cotinine in hair may be more appropriate for longer-term exposure to tobacco. The purpose of this study is to comparing airborne nicotine levels and hair cotinine level in restaurant workers. Concentration of airborne nicotine and hair nicotine (and cotinine) is closely related to exposed frequency of sidestream smoke in the workplace. Nicotine in hair is a better predictor of airborne nicotine than hair cotinine. Hair nicotine can be a useful tool to assess ETS exposure interventions. It may have limiting levels of ETS exposure by placing regulatory restrictions on smoking in workplaces and in public spaces.

• Proceedings of the Korean Nutrition Society Conference
• /
• 1999.05b
• /
• pp.116-117
• /
• 1999

• Journal of Environmental Health Sciences
• /
• v.48 no.4
• /
• pp.216-226
• /
• 2022

Background: The amount of smoking in adolescence increases with a younger age of smoking initiation and affects physical health. To establish and evaluate smoking-related policies, it is important to determine actual smoking status. Validation of self-reported questionnaires can identify the accuracy of the questionnaire data reflecting smoking status. Objectives: The purpose of this study was to evaluate the validity of self-reported smoking status and identify factors affecting the accuracy of self-reported smoking in South Korean adolescents. Methods: This study investigated the consistency between cotinine concentrations and self-reported questionnaire data through the analysis of urine samples collected from 922 adolescents aged 13~18 among the participants of Cycle 3 of the Korean National Environmental Health Survey. Smoking status was classified using the cotinine cut-off point of 39.85 ㎍/L in adolescents, and factors affecting the accuracy were analyzed through multiple logistic regression analysis. Results: The smoking rates according to the self-reported questionnaire and cut-off point-based cotinine concentrations among adolescents were 3.1% and 5.1%, respectively. The results found 97.1% consistency between self-reported smokers and smokers according to cotinine concentration. Factors affecting the discrepancy showed a significant relationship, including gender, secondhand smoke, and use of e-cigarettes. Conclusions: The results can be used as basic data to establish a smoking policy for adolescents through continuous monitoring and improvement of questionnaire items of factors affecting the discrepancy.