• Journal of the Korean Data and Information Science Society
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• 제26권6호
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• pp.1175-1188
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• 2015

20년 이상 유지된 낮은 합계출산율은 학령인구 감소로 이어져 고등학교 졸업자 수가 급격히 감소하는 상황에 직면하게 되었고, 교육부는 2014년 1월 향 후 10년간 약 16만 명에 해당하는 대학 입학정원을 강제로 감축하는 대학 구조개혁 추진 계획을 발표였다. 대학의 정원감축은 피할 수 없는 문제이지만, 대학 구조개혁 추진계획의 주된 근거로 교육부가 제시한 것은 통계청의 18세 전국 장래 추계인구와 2014년 전국단위 대학정원의 비교자료뿐이다. 대학정원의 감축이 학생, 대학, 지역경제까지 큰 파장을 미치는 것임을 고려할 때, 교육부의 근거가 세밀하지 못한 것에 아쉬움이 따를 수밖에 없다. 따라서 본 연구에서는 고3 수험생, 재수생을 포함하는 대학수학능력시험 응시자를 16개 시도 별로 2032년까지 전망하고 지역별 특성을 비교하였다. 16개 시도 별 현재의 대학정원이 2032년까지 계속된다는 가정 아래서 16개 시도 별 대학수학능력시험 응시자 전망결과를 이용하여 지역별 대학 충원율을 산출을 시도하였으나, 수험생의 지역 간 이동을 반영할 수 없어 현실적인 전망결과를 산출하지 못하였다. 이 문제의 해결을 위하여 본 연구에서는 2014학년도 대학배치표 상의 학과순위가 계속 유지된다는 가정에서 전체 일반대학 7,277개 학과 순위를 추정하고, 이 학과들의 정원을 전체 대학 정원에서 차감해 가는 방법으로 지역별 대학 충원율을 2032년까지 산출하였다. 16개 시도 별로 산출된 대학 충원율은 전국단위로 보았을 때보다 지역별 특성과 문제점을 좀 더 확연하게 보여주었다.

• 한국사회복지학
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• 제65권3호
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• pp.131-153
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• 2013

본 연구에서는 사회복지조직에서 사회복지사를 채용할 때 적용하는 채용기준에 대해 알아보기 위해 인사권을 가진 관리자급을 대상으로 채용기준에 대한 상대적 중요도 및 우선순위에 대한 연구를 진행하고자 하였다. 연구의 목적을 달성하기 위해 사회복지시설 46곳을 방문하여 개별면접을 실시한 후 공통적인 의견으로 나타난 7개 영역(업무능력, 자격 및 경력, 시설과의 적합성, 대상자 특성, 인맥 및 추천, 근무자세, 종교 및 신앙) 33개 문항을 구성한 다음 2012년 10월부터 2013년 4월까지 약 6개월간 전국 16개 시, 도를 대상으로 설문을 진행하였다. 설문을 통해 160부가 회수되었으며, 회수된 설문지 가운데 일관성 비율(C.R)이 0.2 이하인 45부가 최종 분석에 사용되었다. 분석을 통해 상위영역과 하위 영역별 우선순위를 도출한 다음 이용시설과 생활시설 간 비교분석을 통한 결과를 제시하였다. 분석결과, 상위영역에서는 업무능력이 가장 중요한 영역으로 나타났으며, 전체 33항목에 대한 순위에서는 이용시설과 생활시설 모두 기관과 근무자의 마인드 일치도가 가장 중요한 항목인 것으로 나타났다. 이러한 결과를 토대로 연구의 제한점과 함의를 제안하였다.

• Journal of the Korean Data and Information Science Society
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• 제25권4호
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• pp.727-736
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• 2014

대졸 취업자들의 특성을 분석하기 위해 주로 모수적인 접근방법을 사용해 온 기존의 연구와는 달리, 본 연구에서는 R 프로그램을 이용하여 데이터 시각화에 초점을 맞추어 분석하였다. 이를 위해 취업여부에 미치는 개인특성 변수들의 유사성 분석을 위해 다중대응분석을 실시하였다. 또한 취업여부에 영향을 미치는 개인특성 변수들의 고차 상호작용효과를 분석하기 위해 의사결정나무분석을 실시하였다. 그리고 연관성분석을 이용한 연관성 규칙을 계산하여 개인특성 변수들이 취업여부에 미치는 효과를 분석하고, 연관성규칙의 결과를 사회연결망분석의 연결망 구조로 시각화 하였다. 분석결과 다음과 같은 주요 결과를 얻었다. 첫째, 취업여부에 영향을 미치는 변수들로는 평균평점, 계열, 강의평가 점수, 성별 등으로 나타났다. 둘째, 평균평점과 강의평가점수가 보통이상으로 높고 자연계열인 경우 취업 가능성이 높음을 알 수 있다. 또한 수시모집으로 입학한 연령이 낮은 졸업생이 취업가능성이 높게 나타났다. 셋째, 평균평점이 낮고 예체능 계열이며 연령이 높은 대졸자들이 취업가능성이 낮음을 알 수 있다. 또한 예체능 계열의 단일전공을 한 여학생들의 경우도 취업가능성이 높지 않음을 알 수 있다.

• 대한한의학회지
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• 제43권2호
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• pp.42-50
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• 2022

Objectives: The purpose of this study is to investigate the characteristics of female infertility patients who come to Korean medicine clinics and analyze the trends of Korean medicine treatment methods and the effects of female infertility by registry data. Methods: We are recruiting study participants from Korean medicine hospitals and clinics. If female infertility patients come, we will ask them to register for this study. After enrollment, we will collect demographic information, treatment methods, pregnancy results, adverse events, and treatment costs. Result: First, we will analyze the characteristics of patients, the status of the use of Korean medicine treatment interventions, the cost status of Korean medicine infertility treatment, and the delivery characteristics of pregnant women after Korean medicine treatment. Second, we will analyze the effectiveness of Korean medicine treatment. The primary outcome is clinical pregnancy rate, and secondary outcomes are 12-week pregnancy maintenance rate, degree of dysmenorrhea and premenstrual syndrome, stress level, and health-related quality of life score. Discussion: This study is the first observational multi-center study in Korea for female infertility. By establishing the registry, we are creating a resource that contains patient-reported outcome measures for female infertility. The registry is expected to provide valuable data for developing Korean medicine Clinical practice guidelines for female infertility.

• 한국수정란이식학회지
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• 제33권4호
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• pp.229-235
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• 2018

Polo-like kinase 1 (Plk1) has been known to be a critical element in cell division including centrosome maturation, cytokinesis and spindle formation in somatic, cancer, and mammalian embryonic cells. In particular, Plk1 is highly expressed in cancer cells. Plk1 inhibitors, such as BI2536, have been widely used to prevent cell division as an anticancer drug. In this study, the fertilized murine oocytes were treated with BI2536 for 30 min after recovery from the oviduct to investigate the effect of down-regulation of Plk1 in the in vivo-fertilized murine embryos. Then, the localization and expression of Plk1 was observed by immunofluorescence staining. The sperm which had entered into the oocyte cytoplasm did not form male pronuclei in BI2536-treated oocytes. The BI2536-treated oocytes showed significantly lower expression of Plk1 than non-treated control group. In addition, alpha-tubulin and Plk1 gathered around sperm head in non-treated oocytes, while BI2536-treated oocytes did not show this phenomenon. The present study demonstrates that the Plk1 inhibitor, BI2536, hinders fertilization by inhibiting the formation of murine male pronucleus.

• 한국환경복원기술학회지
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• 제19권2호
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• pp.121-135
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• 2016

The present study is an analysis of the monitoring results of the four areas that underwent the experimental construction of Straw-net+seedspray, Vegetation media spray method(t=2cm), and Vegetation media spray method(t=3cm), with the purpose of selecting the adequate revegetation of cutting slopes in weathered granite soil. Cutting slopes are mostly designed in the Straw-net+seedspray method, but since weathered granite soil slopes tend to have an infertile soil quality that runs down, it is difficult for seed germination and growth. It is difficult to apply Straw-net+seedspray to weathered granite soil slopes considering the germination rate and coverage rate of the Straw-net+seedspray method, which accompanies erosion and scouring. The final conclusions are summarized as follows. First, Straw-net+seedspray has difficulty recruiting plants to infertile weathered granite soil, which results in a lower coverage rate and fewer species, so it is not adequate construction method. Second, Vegetation spraying methods with wet media are more advantageous in early revegetation. The wet construction methods are faster than the dry construction methods in terms of early germination and its early growth are more excellent. Third, when constructing Vegetation spray methods with dry media, it were more advantageous if the thickness was thicker. When the soil-media is thicker, the soil is resilient to droughts, so the thickness must be flexibly applied according to the soil quality and slant of the weathered granite soil slope. The present study is a monitoring result for some areas of Gangwon-do, so its results may differ from other areas.

• 보건의료산업학회지
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• 제6권3호
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• pp.1-11
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• 2012

The purpose of this study is to identify the effects of emergency medical technicians' personal traits and job characteristics on job/social stress, job satisfaction, role conflicts, organizational commitment, and self-efficacy. The study population was emergency medical technicians who is working at the hospitals in Yeungnam province. The 200 questionnaires were administered by using ground mail, e-mail, and personal visits and 156 questionnaires were returned(82.5% response rate). Social stress, job satisfaction and role conflicts were significantly determined by personal traits and job characteristic variables. However, job stress, organizational commitment and self-efficacy was only significantly determined by job characteristic variables. In social stress and role conflicts, the subjects with challenge, sociability, acceptance and prudence traits were tend to be significantly higher scores compared to the stability traits. Additionally, among social stress regression models, adding job characteristics to the personal traits model, $R^2$ was increased up to 19% and adding personal traits to the job characteristics model, $R^2$ was increased up to 14%. In conclusion, the study found that personal traits and job characteristics are important variables in explaining social stress, job satisfaction and role conflicts, that would have important managerial implications for recruiting, hiring and managing either new or current emergency medical technicians efficiently.

• Clinical and Experimental Reproductive Medicine
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• 제39권4호
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• pp.161-165
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• 2012

Objective: To evaluate the effect of hysterosalpingo-contrast sonography (HyCoSy) on natural conception in the infertile patient. Methods: We conducted a prospective observational study recruiting 180 patients admitted to Infertility Center of Ferrara University from January 2010 to February 2012. The essential inclusion criteria was the couple's desire to perform only diagnostic evaluation on infertility causes and to wait for natural conception before proceeding with further management. Couples were investigated with hormonal profile, semen analysis and HyCoSy. Expected time for spontaneous pregnancy was 180 days from HyCoSy. First datation sonography of pregnancy was used calculating time elapsed from HyCoSy at conception. Results: Forty patients (22.2%) obtained spontaneous pregnancy within 6 months after HyCoSy. The mean of "conception time" was 75 days. The pregnancy rate was significantly higher in the first 30 days (45%) compared to other the months of observation (p<0.0005). Multiple linear regression analysis showed that maternal age and sterility duration proved independent variables in detecting the "conception time" after HyCoSy (t=3.742, p=0.001, t=2.371, p=0.02, respectively). Conclusion: A possible beneficial effect of HyCoSy is feasible especially in the days following its execution. This temporal correlation supports its therapeutic use.

• BMB Reports
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• 제53권12호
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• pp.634-639
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• 2020

In prostate cancer, the androgen receptor (AR) transcription factor is a major regulator of cell proliferation and metastasis. To identify new AR regulators, we focused on Mixed lineage leukemia 5 (MLL5), a histone-regulating enzyme, because significantly higher MLL5 expression was detected in prostate cancer tissues than in matching normal tissues. When we expressed shRNAs targeting MLL5 gene in prostate cancer cell line, the growth rate and AR activity were reduced compared to those in control cells, and migration ability of the knockdown cells was reduced significantly. To determine the molecular mechanisms of MLL5 on AR activity, we proved that AR physically interacted with MLL5 and other co-factors, including SET-1 and HCF-1, using an immunoprecipitation method. The chromatin immunoprecipitation analysis showed reduced binding of MLL5, co-factors, and AR enzymes to AR target gene promoters in MLL5 shRNA-expressing cells. Histone H3K4 methylation on the AR target gene promoters was reduced, and H3K9 methylation at the same site was increased in MLL5 knockdown cells. Finally, xenograft tumor formation revealed that reduction of MLL5 in prostate cancer cells retarded tumor growth. Our results thus demonstrate the important role of MLL5 as a new epigenetic regulator of AR in prostate cancer.

• Physical Therapy Rehabilitation Science
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• 제10권2호
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• pp.156-160
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• 2021

Objective: Low back pain easily becomes chronic and has a high recurrence rate. Therefore, it is most important to prevent chronicity and reduce the risk of recurrence in the early stages of back pain or at the stage with mild pain. Therefore, this study was conducted to compare hip joint muscle strength, trunk muscle endurance, and pelvic alignment between subjects with mild low back pain and subjects without back pain. Design: Crossed-sectional study Methods: The study was conducted by recruiting 30 students in their twenties who are enrolled in K University in Gyeongsangnam-do, and classifying them into 15 patients with mild back pain and 15 patients with normal. The subjects who participated in the experiment were measured for hip flexor and extensor muscle strength, trunk flexion and extension muscle endurance, and pelvic alignment. To measure hip joint muscle strength, biodex was used, and muscle endurance of the trunk was recorded at the end range of the trunk flexion and extension. And pelvic alignment was measured using Formetric 4D. Results: There were no significant differences in hip joint muscle strength, pelvic alignment, and trunk extension muscle endurance. The retention time was found to be significantly shorter in the mild low back pain group than in the normal group for trunk flexion muscle endurance. Conclusions: In the early stages of back pain or in the mild pain stage, training to increase muscle endurance of the flexor muscles may be helpful.