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Practice guidelines for managing extrahepatic biliary tract cancers

  • Hyung Sun Kim;Mee Joo Kang;Jingu Kang;Kyubo Kim;Bohyun Kim;Seong-Hun Kim;Soo Jin Kim;Yong-Il Kim;Joo Young Kim;Jin Sil Kim;Haeryoung Kim;Hyo Jung Kim;Ji Hae Nahm;Won Suk Park;Eunkyu Park;Joo Kyung Park;Jin Myung Park;Byeong Jun Song;Yong Chan Shin;Keun Soo Ahn;Sang Myung Woo;Jeong Il Yu;Changhoon Yoo;Kyoungbun Lee;Dong Ho Lee;Myung Ah Lee;Seung Eun Lee;Ik Jae Lee;Huisong Lee;Jung Ho Im;Kee-Taek Jang;Hye Young Jang;Sun-Young Jun;Hong Jae Chon;Min Kyu Jung;Yong Eun Chung;Jae Uk Chong;Eunae Cho;Eui Kyu Chie;Sae Byeol Choi;Seo-Yeon Choi;Seong Ji Choi;Joon Young Choi;Hye-Jeong Choi;Seung-Mo Hong;Ji Hyung Hong;Tae Ho Hong;Shin Hye Hwang;In Gyu Hwang;Joon Seong Park
    • 한국간담췌외과학회지
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    • 제28권2호
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    • pp.161-202
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    • 2024
  • Backgrounds/Aims: Reported incidence of extrahepatic bile duct cancer is higher in Asians than in Western populations. Korea, in particular, is one of the countries with the highest incidence rates of extrahepatic bile duct cancer in the world. Although research and innovative therapeutic modalities for extrahepatic bile duct cancer are emerging, clinical guidelines are currently unavailable in Korea. The Korean Society of Hepato-Biliary-Pancreatic Surgery in collaboration with related societies (Korean Pancreatic and Biliary Surgery Society, Korean Society of Abdominal Radiology, Korean Society of Medical Oncology, Korean Society of Radiation Oncology, Korean Society of Pathologists, and Korean Society of Nuclear Medicine) decided to establish clinical guideline for extrahepatic bile duct cancer in June 2021. Methods: Contents of the guidelines were developed through subgroup meetings for each key question and a preliminary draft was finalized through a Clinical Guidelines Committee workshop. Results: In November 2021, the finalized draft was presented for public scrutiny during a formal hearing. Conclusions: The extrahepatic guideline committee believed that this guideline could be helpful in the treatment of patients.

Clinical and Genetic Features of Korean Inherited Arrhythmia Probands

  • Joo Hee Jeong;Suk-Kyu Oh;Yun Gi Kim;Yun Young Choi;Hyoung Seok Lee;Jaemin Shim;Yae Min Park;Jun-Hyung Kim;Yong-Seog Oh;Nam-Ho Kim;Hui-Nam Pak;Young Keun On;Hyung Wook Park;Gyo-Seung Hwang;Dae-Kyeong Kim;Young-Ah Park;Hyoung-Seob Park;Yongkeun Cho;Seil Oh;Jong-Il Choi;Young-Hoon Kim
    • Korean Circulation Journal
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    • 제53권10호
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    • pp.693-707
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    • 2023
  • Background and Objectives: Inherited arrhythmia (IA) is a more common cause of sudden cardiac death in Asian population, but little is known about the genetic background of Asian IA probands. We aimed to investigate the clinical characteristics and analyze the genetic underpinnings of IA in a Korean cohort. Methods: This study was conducted in a multicenter cohort of the Korean IA Registry from 2014 to 2017. Genetic testing was performed using a next-generation sequencing panel including 174 causative genes of cardiovascular disease. Results: Among the 265 IA probands, idiopathic ventricular fibrillation (IVF) and Brugada Syndrome (BrS) was the most prevalent diseases (96 and 95 cases respectively), followed by long QT syndrome (LQTS, n=54). Two-hundred-sixteen probands underwent genetic testing, and 69 probands (31.9%) were detected with genetic variant, with yield of pathogenic or likely pathogenic variant as 6.4%. Left ventricular ejection fraction was significantly lower in genotype positive probands (54.7±11.3 vs. 59.3±9.2%, p=0.005). IVF probands showed highest yield of positive genotype (54.0%), followed by LQTS (23.8%), and BrS (19.5%). Conclusions: There were significant differences in clinical characteristics and genetic yields among BrS, LQTS, and IVF. Genetic testing did not provide better yield for BrS and LQTS. On the other hand, in IVF, genetic testing using multiple gene panel might enable the molecular diagnosis of concealed genotype, which may alter future clinical diagnosis and management strategies.

The Introduction of Adverse Drug Reaction (ADR) Monitoring System

  • Jung, Sun-Hoi;Park, Kyoung-Ho;Soh, Ok-Kyoung;Lee, Byung-Gu;Park, Kaung-Jun;Bae, Guen-Shub;Jang, In-Jin;Kim, Youn-Gun;Kim, Ju-Sung;Chae, In-Ho;Kim, Yeun-Su;Ha, Jong-Won;Song, Yong-Sung;Choung, Jon-Ho;Kyun, Jin-Soo;Kim, Sang-Yeun;Go, Zae-Sung;Park, Jun-Dong;Song, Kyeng-Ja;Park, Byung-Joo
    • 대한약학회:학술대회논문집
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    • 대한약학회 2001년도 Proceedings of International Convention of the Pharmaceutical Society of Korea
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    • pp.323-323
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    • 2001
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