• Archives of Pharmacal Research
• /
• v.9 no.2
• /
• pp.75-79
• /
• 1986

The effect of phenothiazine derivatives on the thermotropic transition of liposomal lipid bilayer made of dipalmitoyl phosphatidylchline and dipalmitoyl phosphatidic acid was investigated with differential scanning calorimetry. The thermograms of the liposomal bilayer incorporated with levomepromazine, chlopromazine, prochloperazine, perphenazine and fluphenazine were obtained and the size of cooperative unit of the transition were calculated from the ratio of the van't Hoff enthalpy change to the calculated enthalpy change of the transition. The results showed that incorporation of phenothiazine derivatives into the liposomal bilayer reduced the transition temperature at which the transition from solid state to liquid-crystalline state occurs, and broadened the thermogram peaks. Phenothiazine derivatives also significantly reduced the size of cooperative unit of the transition. The effect of the drugs was proportional to the concentration of the drug in the bilayer. This means that phenothiazine derivatives might have significant fluidizing effects on the biomembrane. The sizes of cooperative unit were successfully corrlated with phar-macological activities of the drugs and the surface pressure increases of lipid monolayer by these drugs. These correlations might be ascribed to a possible hydrophobic nature of interaction between the biomembrane and the drugs involved in their pharmacology.

• Communications for Statistical Applications and Methods
• /
• v.19 no.1
• /
• pp.177-182
• /
• 2012

A structural break in the level as well as in the innovation variance has often been exhibited in economic time series. In this paper we propose robust unit root tests based on a sign-type test statistic when a time series has a shift in its level and the corresponding volatility. The proposed tests are robust to a wide class of partially stationary processes with heavy-tailed errors, and have an exact binomial null distribution. Our tests are not affected by the size or location of the break. We set the structural break under the null and the alternative hypotheses to relieve a possible vagueness in interpreting test results in empirical work. The null hypothesis implies a unit root process with level shifts and the alternative connotes a stationary process with level shifts. The Monte Carlo simulation shows that our tests have stable size than the OLSE based tests.

• Journal of The Korea Institute of Healthcare Architecture
• /
• v.2 no.3
• /
• pp.21-33
• /
• 1996

This study aims to decide optimized size of a dental care unit. The efficient treatment room makes its user so comfortable that treatment can be easier and faster. Therefore, an operating room is the most important part in the dental hospital. This study focused on the outpatient care unit of dental hospital. The hospital for the case study is selected recently rebuilt dental university hospital. This study is to survey the behavior of all user in the sector and treatment unit. As the result, optimized plan type and size for each cases are proposed.

• Transactions of Materials Processing
• /
• v.15 no.1 s.82
• /
• pp.21-26
• /
• 2006

A optical head unit for nano optical probe array was developed. The optical probe array is generated by Talbot effect. The shape and thickness of microlens array(MLA) were designed to minimize the spot size at the foci of MLA. To increase the optical efficiency of the system and obtain the large tolerance for fabrication, aperture size was theoretically optimized. Then microlens illuminated aperture array(MLIAA) as an optical head unit was fabricated using a ultra violet(UV) molding process on aluminum aperture array. In this process, Al aperture array was fabricated separately using the photolithography and reactive ion etching(RIE) process. Optical properties of the generated optical probes were measured and compared at Talbot distance from the aperture array having a diameter of $1{\mu}m$ and MLIAA.

• Journal of The Korean Society of Agricultural Engineers
• /
• v.50 no.4
• /
• pp.51-58
• /
• 2008

Unit costs for energy production in bioenergy facilities are dependent upon both fixed cost for facility construction and operational costs including biomass feedstock supply. With the increase of capacity, unit fixed cost could be decreased while supply cost tends to increase due to the longer transportation distance. It is desirable to take into account biomass availability in planning bioenergy facilities. A cumulative curve relationship was proposed to relate biomass availability and cumulative products of biomass amount and transportation distance. Optimum size of gasification facilities was affected by collection cost, biomass cumulative relationship. Based on biomass availability of Icheon-City, optimum sizes were about $400kW_{th}$ for gas production, and about $200kW_{el}$ for power generation. Unit cost of bioenergy production could be substantially reduced by reducing collection cost through supplying biomass from diverse sources including land development areas where significant amount of waste wood is generated. When planning bioenergy facilities, however, biomass availability and spatial distribution are key factors in determining the size of capacity.

• Proceedings of the Korean Society for Technology of Plasticity Conference
• /
• 2005.09a
• /
• pp.29-34
• /
• 2005

A optical head unit for nano optical probe away was developed. The optical probe array is generated by Talbot effect. The shape and thickness of microlens array(MLA) were designed to minimize the spot size at the foci of MLA. To increase the optical efficiency of the system and obtain the large tolerance for fabrication, aperture size was theoretically optimized. Then microlens illuminated aperture array(MLIAA) as an optical head unit was fabricated using a ultra violet(UV) molding process on aluminum aperture array. In this process, Al aperture array was fabricated separately using the photolithography and reactive ion etching(RIE) process. Optical properties of the generated optical probes were measured and compared at Talbot distance from the aperture array having a diameter of $1{\mu}m$ and MLIAA.

• Journal of the Korean housing association
• /
• v.21 no.6
• /
• pp.81-90
• /
• 2010

The existing most studies on the apartment sales prices have been limited to relatively small size apartment complexes and have not categorized the apartment complexes based on the number of households. Some of them uses the apartment-related indices such as regional value estimates, sales unit price, and view right values. In the case of Seoul Metropolitan Area, the size of apartment complex has been growing to the level of large complex over more than 1,000 households through new town development, redevelopment and reconstruction. People prefers to choose a large scale complex instead of small complex based on their perception that a large scale apartment complex provides more conveniences in living. The result of this analysis revealed that the variables chosen as important determinants of the hedonic price model for large scale apartment complexes were square meters of apartment unit, rent/price ratio, number of bays, distance to the nearest subway station, and heating system method. This means that the sales price of apartment unit will be higher as the square meters of apartment unit increase, as the rent/price ratio decreases, as the distance to the nearest subway station increases, and as the number of bays increase.

• Korean Institute of Interior Design Journal
• /
• v.13 no.2
• /
• pp.109-119
• /
• 2004

This study was intended to grasp the housing unit plan which the residents preferred. The subjects were 100 housewives who lived in 85$m^2$ sized housing units in the New Apartment Complex, Gimhae. First, four elements of unit plan were selected on the basis of the results of the POE which was carried out for the same subject the size of master bedroom and living room, the openness of dining/kitchen from living room, the openness of living room from entrance, and whether or not a bathtub or a shower booth is in bathroom. Then, eight design alternatives of unit plan made by combination of these four elements according to orthoplan were visualized by computer media. This visualized tool was used for collecting data. The results of the study were as follows: The important determinants of the residents' preferences for unit plan were the size of master bedroom and living room and the openness of living room from entrance. The residents preferred the unit plan which living room was large and the view from living room to dining/kitchen was open. Also, the important elements were different according to the characteristics of the residents. Therefore, the housing alternatives which are flexible and optional would be desirable.

• Plant Journal
• /
• v.13 no.3
• /
• pp.30-35
• /
• 2017

Module can be categorized as PAS(Pre-Assembled Steel structure), PAR(Pre-Assembled pipe Rack), PAU(Pre-Assembled Unit), VAU(Vendor Assembled Unit) and VPU(Vendor Package Unit). At the stage of design and fabrication of module, the condition of land and ocean transportation is considered and these conditions are reflected on the module division design. The control of the module's center of gravity is important to transport and install modules safely and the steel structure should have the strength enough to resist the sea acceleration force during the ocean transportation. The transportation condition and the installation method influence the size and weight of module. The size and weight of module are considered for the design of module division.

• Korean Journal of Applied Biomechanics
• /
• v.22 no.3
• /
• pp.373-378
• /
• 2012

The purpose of this study was to develop an electric riding machine for cycle fitting to control riding posture easily, to measure frame size quantitatively, and to overcome disadvantages of the traditional systems. The electric riding machine consisted of actuator, load controller, and display & control unit. The actuator unit by BLDC(BrushLess Direct Current) motor drives the saddle height up and down, the crank forward and backward, the handlebar up and down, and the handlebar forward and backward. The load controller unit controls loads by Eddy current controller with electromagnet and aluminum circular plate. The display & control unit consisted of frame size controller and display panel which shows top tube length(485~663mm), head tube length(85~243mm), seat tube length(481~671mm), and seat tube angle($62.7{\sim}76.4^{\circ}$). The range of frame size control for developed electric riding machine did not have difference compared to traditional commercial systems, but quantitative and precise control with 0.1 mm length and $0.1^{\circ}$ angle was possible through digital measurement. Unlike traditional commercial systems, frame size control was possible during riding through motor driven method, thus fitting duration decreased. It is necessary for further improvement to have feedback from users. It is believed that developed electric riding machine can help to develop domestic fitting system.