• Journal of Nutrition and Health
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• 제30권6호
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• pp.648-657
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• 1997

This study was to investigate the ultrasonographic liver fat density , obesity index, and serum lipids. One hundred and one (43 males, 58 females)healthy adult subjects were examined using anthropometric indices, biochemical measurements and ultrasonography. The average levels of ULFD, TC, TG, HDL-C, LDL-C were 122.4mg/dl, 201.1mg/dl, 144.9mg/dl, 49.8mg/dl 122.3mg/dl, respectively for males and 117.9mg/dl, 199.1mg/dl, 130.6mg/dl, 50.6mg/dl, 122.3mg/dl, respectively for females. Males had higher levels of ULFD, TC , TPH, LPH and AI than the females but the differences were not significantly. LDL-C, TC , LPH, TPH and AI of obese groups by KI were significantly higher than those of nonobese groups. Ultrasonnographic liver fat density showed positive correlation with BW, W/H and TG. Objective measurement of ultrasonographic liver fat density is useful for the parameter of obesity.

• Journal of Nutrition and Health
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• 제31권1호
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• pp.28-35
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• 1998

This study was done to investigate the relationship between ultrasonograph fat density (ULFD) using objective measurement and serum enzymes for testing liver function in 101 healthy adults(43 males and 58 females). Average serum enzyme activities in males and females were GOT27.111U/L and 22.46IU/L, GPT 34.06IU/L and 18.501U/L, and ${\gamma}$-GTP 37.67IU/L and 17.201U/L, respectively. Males showed significantly higher activities of GPT and ${\gamma}$-GTP than females. ULFD of the obese group (BMI$\geq$25) was significantly higher than that of the nonobese group. GOT, GPT, and ${\gamma}$-GTP tended to be high in the obese group. GPT and ${\gamma}$-GTP of the high TG group (TG$\geq$170) tended to be markedly high for males, but not for females. GPT was positively correlated with ULFD, body weight , and weight-to-height, ratio, and ${\gamma}$-GTP was positively correlated with body weight, weight-to-height ratio. BNI, and KI. ULFD and ${\gamma}$-GTP were positively correlated with serum TG. These results suggests that , among serum enzymes for testing liver function, GPT has a close relationship with ULFD using objective measurement, while GOT does not. Also , ${\gamma}$-GTP has a close relationship with parameters for obesity.

• Journal of Preventive Medicine and Public Health
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• 제26권2호
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• pp.179-191
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• 1993

Generally fatty liver is attributed either to chronic alcoholism, diabetes mellitus, or obesity. Based upon this commonly held clinical brief, this study was conducted to investigate the contributing factors of fatty liver and odds ratio (OR) of known contributing factors. A sample of 310 male participants, who visited at Seoul Paik Automated Multiphasic Health Testing System from November 1991 to December 1991, was separated into 112 cases and 198 controls by ultrasonographic fin ding. There were statistically significant difference between fatty liver and normal in triglyceride (TG), body mass index (BMI), alanine aminotransferase (ALT), high density lipoprotein cholesterol (HDL-C), fasting blood sugar (FBS), alcohol consumption, low density lipoprotein cholesterol (LDL-C), total cholesterol, gamma-glutamyl transferase ($\gamma$-GT), duration of alcohol intake and alkaline phosphatase (Alk.P)(P<0.01, P<0.05). The statistically significant elevated odds ratio were noted for TG (4.48, confidence interval (CI) 2.66-7.55, P=0.000), alcohol consumption(3.24, CI 1.56-6.23, P=0.002), BMI(3.05, CI 1.87-4.97, P=0.000), and FBS (2.59, CI 1.53-4.40, P=0,000). In summary, it is suggested that the fatty liver could be preventive by avoiding such deleterious factors as high fat diet, alcohol and obesity.