• Animal Systematics, Evolution and Diversity
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• v.19 no.2
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• pp.227-235
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• 2003

The euplotid hypotrich collected from a puddle, Jeju-do in 2002 and cultured in the laboratory was identified as Euplotes muscorum Dragesco, 1970. The species is reported for the first time from Korea. The description was based on the observation of living specimens, protargol impregnation and biometrical analysis. This species is characterized by following diagnosis: 63-78 ${\mu}m$ in length, 40-52 ${\mu}m$ in width in vivo, 9 frontoventral cirri, 5 transverse cirri,4 caudal cirri, 1 micro- and macronucleus, adoral zone of membranelles with 32-36 adoral membranelles covering approximately 2/3 of body length, 8 dorsal kineties, mid-dorsal kinety with 20-24 cilia 3nd dargyrome complex type. This species with 9 frontoventral cirrotype is very similar to E. muscicola Kahl, 1932. The differences between these two species are: E. muscorum has 8 dorsal kineties and complex dargyrome type, while E. muscicola 9 dorsal kineties and multiple dargyrome type.

• Nuclear Engineering and Technology
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• v.52 no.9
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• pp.2009-2016
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• 2020

A nuclear power plant is a large complex system with tens of thousands of components. To ensure plant safety, the early and accurate diagnosis of abnormal situations is an important factor. To prevent misdiagnosis, operating procedures provide the anticipated symptoms of abnormal situations. While the more severe emergency situations total less than ten cases and can be diagnosed by dozens of key plant parameters, abnormal situations on the other hand include hundreds of cases and a multitude of parameters that should be considered for diagnosis. The tasks required of operators to select the appropriate operating procedure by monitoring large amounts of information within a limited amount of time can burden operators. This paper aims to develop a system that can, in a short time and with high accuracy, select the appropriate operating procedure and sub-procedure in an abnormal situation. Correspondingly, the proposed model has two levels of prediction to determine the procedure level and the detailed cause of an event. Simulations were conducted to evaluate the developed model, with results demonstrating high levels of performance. The model is expected to reduce the workload of operators in abnormal situations by providing the appropriate procedure to ultimately improve plant safety.

• Korean Circulation Journal
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• v.53 no.3
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• pp.113-133
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• 2023

Owing to a large-jeopardized myocardium, left main coronary artery disease (LMCAD) represents the substantial high-risk anatomical subset of obstructive coronary artery disease. For several decades, coronary artery bypass grafting (CABG) has been the "gold standard" treatment for LMCAD. Along with advances in CABG, percutaneous coronary intervention (PCI) has also dramatically evolved over time in conjunction with advances in the stent or device technology, adjunct pharmacotherapy, accumulated experiences, and practice changes, establishing its position as a safe, reasonable treatment option for such a complex disease. Until recently, several randomized clinical trials, meta-analyses, and observational registries comparing PCI and CABG for LMCAD have shown comparable long-term survival with tradeoffs between early and late risk-benefit of each treatment. Despite this, there are still several unmet issues for revascularization strategy and management for LMCAD. This review article summarized updated knowledge on evolution and clinical evidence on the treatment of LMCAD, with a focus on the comparison of state-of-the-art PCI with CABG.

• Tuberculosis and Respiratory Diseases
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• v.72 no.5
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• pp.452-456
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• 2012

Disseminated Mycobacterium avium complex (MAC) infection can occur in immunocompromised patients, and rarely in immunocompetent subjects. Due to the extensive distribution of the disease, clinical presentation of disseminated MAC may mimic malignancies, and thorough examinations are required in order to make accurate diagnosis. We report a case of disseminated Mycobacterium intracellulare disease in an immunocompetent patient, which involved the lung, lymph nodes, spleen, and multiple bones. F-18 fluorodeoxyglucose positron-emission tomography imaging showed multiple hypermetabolic lesions, which are suggestive of typical hematogenous metastasis. However, there was no evidence of malignancy in serial biopsies, and M. intracellulare was repeatedly cultured from respiratory specimens and bones. Herein, we should know that disseminated infection can occur in the immunocompetent subjects, and it can mimic malignancies.

• Journal of Ocean Engineering and Technology
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• v.18 no.1
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• pp.7-9
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• 2004

Using the solution to th contour integral of the complex logarithmic function ${\oint}_cIn(z-z_{0})dz$, the following definite integral, derived from the formula to calculate the forces exerted to n circular cylinder by the discrete vortices shed from it, has been evaluated (equation omitted)

• Journal of Korean Society for Atmospheric Environment
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• v.32 no.4
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• pp.394-407
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• 2016

The spatial air pollution distribution of the Ulsan metropolitan region (UMR) was analyzed using monitoring data and high-resolution numerical simulations. A three-year (2011~2014) analysis for the average concentrations from the 13 air quality monitoring sites in the UMR showed that $SO_2$ and $PM_{10}$ levels in industrial regions were much higher than those in other regions, whereas spatial differences of $NO_2$ and CO concentrations were not significant. In particular, elevated $O_3$ concentrations were clearly found at urban sites near petrochemical complex area. Results from high-resolution simulations by CMAQ model performed for four months of 2012 showed large spatial variations in grid-average pollutant concentrations between industrial areas and other areas in the UMR, which displayed significant changes with wind pattern by season. It was noted that the increases of $SO_2$ and $PM_{10}$ levels were limited in costal industrial areas or over the area nearby the sea in all seasons. Modeled $O_3$ concentrations were quite low in industrial areas and main urban roads with large $NO_x$ emissions. However, the model presented that all pollutant concentrations were significantly increased in the urban residential areas near the industrial complexes in summer season with increase of southerly wind.

• Journal of Korean Society for Atmospheric Environment
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• v.29 no.6
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• pp.780-788
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• 2013

This study attempted to determine important meteorological parameters related to airborne pollen concentrations in urban areas. Hourly pollen measurement data were prepared from a regular sampling with a volumetric Burkard spore trap at a site in the Ulsan city, during the spring season (March~May) of 2011. Results showed that the daily mean and maximum concentrations for total pollen counts during the spring season were statistically significantly correlated with both air temperature and wind speed; daily mean pollen concentration was the most highly related to daily maximum temperature (r=0.567, p<0.001). It was also identified that pollen concentration has a stronger relationship with wind speed at the rural site than at the urban one, which confirms that strong wind conditions over the pollen sources area can be favorable for pollen dispersal, resulting in increases in airborne pollen concentrations downwind. From the results of an oak-pollen episode analysis, it was found that there was a significant relationship between hourly variation of oak pollen concentrations and dynamic meteorological factors, such as wind and mixing height (representing the boundary layer depth); especially, a strong southwestern wind and elevated mixing height was associated with high nocturnal concentrations of oak pollen. This study suggests that temperature, wind, and mixing height can be important considerations in explaining the pollen concentration variations. Additional examination of complex interactions of multiple meteorological parameters affecting pollen behavior should be carried out in order to better understand and predict the temporal and spatial pollen distribution in urban areas.

• Journal of Korean Society for Atmospheric Environment
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• v.31 no.2
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• pp.181-194
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• 2015

Spatial-temporal meteorological features of the Ulsan metropolitan region (UMR) were analyzed using observations and high-resolution numerical modeling. Long-term trend analysis (1970~2013) showed a significant increase of $0.033^{\circ}Cyr^{-1}$ in the 5-year moving average temperature, although detailed short-term features varied, whereas wind speed and relative humidity over the same period displayed clear decreases of $-0.007ms^{-1}$ and $-0.29%yr^{-1}$, respectively. These trends indicate the effects of regional climate change and urbanization in the UMR. Seasonal variations averaged for the most recent three years, 2011~2013, showed that temperatures in three different regions (urban/industrial, suburban, coastal areas) of the UMR had similar seasonality, but significant differences among them were observed for a certain season. Urban and industrial complex regions were characterized by relatively higher temperatures with large differences (max.: $3.6^{\circ}C$) from that in the coastal area in summer. For wind speed, strong values in the range from 3.3 to $3.9ms^{-1}$ occurred in the coastal areas, with large differences clearly shown between the three regions in September and October. Diurnal variations of temperature were characterized by pronounced differences during the daytime (in summer) or nighttime (in winter) between the three regions. Results from the WRF modeling performed for four months of 2012 showed large variations in gridaverage temperature and winds in the UMR, which displayed significant changes by season. Especially, a clear temperature rise in the urban center was identified in July ($0.6^{\circ}C$ higher than nearby urban areas), and overall, relatively weak winds were simulated over urban and inland suburban regions in all seasons.

• Molecules and Cells
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• v.46 no.6
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• pp.351-359
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• 2023

Deamination of adenine or cytosine in RNA, called RNA editing, is a constitutively active and common modification. The primary role of RNA editing is tagging RNA right after its synthesis so that the endogenous RNA is recognized as self and distinguished from exogenous RNA, such as viral RNA. In addition to this primary function, the direct or indirect effects on gene expression can be utilized in cancer where a high level of RNA editing activity persists. This report identified actin-related protein 2/3 complex inhibitor (ARPIN) as a target of ADAR1 in breast cancer cells. Our comparative RNA sequencing analysis in MCF7 cells revealed that the expression of ARPIN was decreased upon ADAR1 depletion with altered editing on its 3'UTR. However, the expression changes of ARPIN were not dependent on 3'UTR editing but relied on three microRNAs acting on ARPIN. As a result, we found that the migration and invasion of cancer cells were profoundly increased by ADAR1 depletion, and this cellular phenotype was reversed by the exogenous ARPIN expression. Altogether, our data suggest that ADAR1 suppresses breast cancer cell mobility via the upregulation of ARPIN.

• Radiation Oncology Journal
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• v.9 no.1
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• pp.165-170
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• 1991

In breast cancer, the treatment volume presents a relatively complex three dimensional structure. Effective radiation therapy requires the delivery of adequate dose to a large target volume using complex beam arrangements. The technique proposed here is our department's method using asymmetric jaw with appropriate couch, collimator and gantry rotation. This technique has the following advantages: 1) all treatments are given in a single clinical set up 2) it does not require half beam blocks 3) it produces exact geomatric match 4) it is very convenient and easy to use 5) it has daily reproducibility.