• 한국정보통신학회논문지
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• 제21권1호
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• pp.193-198
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• 2017

최근 건강에 대한 관심이 증가함에 따라 사용자의 생체정보를 측정할 수 있는 스마트 워치와 스마트 밴드 등 다양한 웨어러블 디바이스(Wearable Device)들이 연구되고 있다. 그러나 기존의 웨어러블 디바이스들은 측정된 생체정보를 단순 모니터링이나 질병 예방법, 운동량 등을 제공하는 형태로만 서비스하고 있어 실제 사용자가 위험상황이 발생할 경우에 대한 대처는 미흡한 실정이다. 이에 본 논문에서는 이러한 문제점을 해결하기 위해 위험상황 알림 시스템을 제안한다. 아두이노를 통해 가속도 센서와 심박 센서로 측정된 생체정보를 실시간으로 어플리케이션에 전송하고 센서 우선순위 측정과 위험상황 식별 알고리즘을 통해 위험상황을 식별한 후 위험상황이 발생하면 보호자에게 사용자의 현재 위치를 알림 메시지를 전송한다. 이에 따라 보호가 필요한 사용자에게 위험한 상황이 발생하면 신속하게 대처할 수 있을 것으로 사료된다.

• 동서간호학연구지
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• 제18권2호
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• pp.111-119
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• 2012

Purpose: Recently, Neurofeedback training system that based on biofeedback of brain wave was introduced. This study was performed to identify the effects of the improvement of brain function by Neurofeedback training on elders(the 2nd or 3rd grade of long-term care insurance services). Methods: A quasi-experimental design using a nonequivalent control group, pre-post test was used. Total 11 elderly were enrolled in this study (experimental group 5, control group 6). The intervention was conducted 3 times a week for 30 minutes from January to June, 2012 (total 60 times). Chi-square test and Mann-Whitney U-test were used to analyze the data. Results: After the Neurofeedback intervention, attention quotient (AQ), anti-stress quotient (ASQ), emotion quotient (EQ) and brain quotient (BQ) of the experimental group were significantly better than those of the control group. Conclusion: The findings indicate that the Neurofeedback training program was effective in reducing fatigue by AQ, increasing the physical and mental stress resistance by ASQ, emotional balance by EQ and improving of total brain function by BQ. Therefore Neurofeedback training be used as an effective training intervention for the health of elderly in geriatric facility.

• 대한토목학회논문집
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• 제8권4호
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• pp.11-21
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• 1988

20세기에 들어서 포틀랜드 시멘트 콘크리트를 이용한 강성포장은, 콘크리트재료의 구조적인 휨강성과 큰 탄성계수 그리고 내구성을 고려한 경제성 등으로 세계 여러 나라에서 널리 이용되어져 왔다. 그러나, 완벽한 설계 및 시공에도 불구하고, 일부 콘크리트 포장도로에서는(예: 미국 Interstate-10 and 75, 한국의 88고속도로 및 중부 고속도로) 심각한 종적, 횡적 균열 및 침하현상 등으로 보수, 유지의 큰 어려움을 겪고 있는 바, 이러한 문제점을 구조역학적인 입장에서 유한 요소법을 이용한 콘크리트 포장구조의 해석을 통해, 차량 위치 및 온도변화에 따른 최대 파괴응력과 위치, 그리고 최대 처짐등을 고려 하므로써, 콘크리트 포장도로의 구조적인 문제점을 해결하는 데 있다. 본 논문에서는 요즘 미국에서 널리 이용되고 있는 경가가로줄눈(skewed joint)의 효과를 구조역학적으로 해석을 하였다.

• 한국가금학회지
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• 제26권3호
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• pp.149-170
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• 1999

Protozoa of the genus Eimeria are the etiologic agents of avian coccidiosis, the most economically important Parasitic disease for the poultry industry. Coccidia multiply in intestinal epithelial cells of a wide range of hosts, including livestock in addition to poultry. Chemotherapy is extensively used to control coccidiosis. However, development of drug resistance by Eimeria parasites, the intensive cost and labor involved in the identification of new anticoccidial compounds and public awareness of drug residues in foods warrant alternative methods to prevent coccidiocic in the fast growing poultry industry. For these reasons, there is a great interest in developing vaccines against avian coccidiosis. Live Eimeria vaccines confer protective immunity, however a significant disadvantage of using these types of vaccines is their pathogenicity. Live parasites with attenuated pathogenicity also usually produce immunity but may revert back to a pathogenic form and may be contaminated with other pathogenic organisms. Killed Eimeria vaccines are safer but, unlike live attenuated vaccines, are not able to generate cytotoxic T lymphocyte responses. Recombinant vaccines are biochemically purified proteins produced by genetic engineering that consist of particular epitopes or metabolites of Eimeria. Unlike live attenuated organisms, recombinant vaccines do not possess as much risk and generally are able to induce both humoral and cell mediated immunity. DNA vaccines consist of genes encoding immunogenic proteins of pathogens that are directly administered into the host in a manner that the gene is expressed and the resulting protein generates a protective immune response. Although all of these different types of vaccines have been applied to coccidiosis, this disease continues to cause substantial morbidity and mortality in the poultry industry. Future development of an effective vaccine against coccidiosis will depend on further investigation of protective immunity to Eimeria infection and identification of important immundgenic parasite molecules.

• 전기전자학회논문지
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• 제24권2호
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• pp.461-467
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• 2020

오늘날 민간에서 사용 중인 측위 시스템의 대부분은 위성의 신호를 수신하여 현재 위치를 계산하는 글로벌 위성항법 시스템(GNSS; Global Navigation Satellite System)을 기반으로 한다. 미국이 GPS (Global Positioning System)를 통하여 입증한 GNSS의 효용성은 다양한 국가에서 위성항법 시스템을 구축하고 고도화 하도록 이끌었다. 그중 중국은 앞선 IT 기술력과 자금력을 바탕으로 자체 GNSS인 베이더우 위성항법 시스템(BDS; BeiDou Navigation Satellite System)의 급진적인 개발을 성공시켰다. 중국이 빠르게 전 세계로 BDS의 서비스 영역을 확대하고 있는 것을 고려할 때 우리나라에서도 BDS에 대한 체계적인 연구가 요구된다. 따라서 본 논문에서는 BDS의 공개 신호인 B1C에 대한 전반적인 정보를 제공하여 B1C 신호 체계 설계 및 BDS B1C 수신기 설계에 활용될 수 있도록 한다.

• 한국산업보건학회지
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• 제1권2호
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• pp.164-180
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• 1991

For the purpose of contributing to the promotion of health of the employees working at the same kind of department store or similar type of business and the people utilizing them and preparing the basic data for the establishment of mangagement measure by assessing the level of air pollusion at indoor and outodoor of four department store among the distribution service business in Pusan area, authors measured the concentration of sulfur dioxide, nitrogen dioxide, formaldehyde and total suspanded particle according to the measuring height of variable at indoor and outodoor from Aug. 1990. to sep. an. d Jan, 1991 to Feb.: for each two months in summer and winter, and studied by dividing the variable factor into atmospheric factor (temperature, humidity and air velociy) The results are as follows ; 1. The mean concentration of air pollutants at indoor to total subjects was nitrogen dioxide 31.1ppb, sulfur dioxide 51.7ppb, formaldehyde 162.lppb and total suspanded particle $67.7{\mu}g/m^3$, and it was higher in winter than in summer (P>0.05) 2. The mean concentration of formaldehyde to total subjects was higher indoors than outdoors (P<0.001), in case of nitrogen dioxide there was no significant difference and sulfur dioxide and total suspanded particle were higher outdoors than indoors (P<0.05) 3. The concentration of nitrogen dioxide and sulfur dioxide proved to be a adverse correlation, reducing with height. 4. According to the result questioned about the exposure concentration of pollutant and the general symptom caused by the pollutant, nitorgen dioxide and symptom proved to be a positive correlation (P<0.09).

• 농촌지도와개발
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• 제24권2호
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• pp.143-154
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• 2017

본 연구의 목적은 라오스 정부가 농업 농촌 발전을 목적으로 2012년부터 국가 정책으로 추진하고 있는 삼상(Sam Sang, 정치적 실천공약, 분산-분권, 국가적 목표) 농촌발전 프로그램을 소개하고, 한국의 1970년대 새마을운동의 교훈을 분석하여, 라오스 삼상모델에 적용할 수 있는 가능성을 제시하는 것이다. 본 연구의 결과 라오스 정부가 추진하고 있는 삼상 농촌개발정책에 적용할 수 있는 교훈을 다음과 같이 제시하고 있다. 상-하향식의 통합적 개발 접근은 한국 농촌발전에 매우 중요한 영향을 미친 것으로 평가하고 있으며, 놀라운 정책결과를 가져온 요인으로 분석하고 있다. 그리고 주민참여의 중요성을 부각하고 있으며 정책을 집행하는 초기단계에는 마을과 마을주민들의 역량강화를 위해서 정부의 적절한 개입과 역할을 강조하며 이를 통한 주민참여를 유도하여 궁극적으로는 자립적 의지를 통한 지속가능한 농촌개발접근이 되어야 한다고 주장하고 있다.

• 전기전자학회논문지
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• 제7권1호
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• pp.88-96
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• 2003

본 논문에서는 미국내의 상용 PCS 서비스 대역인 $1.9GHz(1.93{\sim}1.99GHz)$대역에서 사용 가능한 선형 전력 증폭기를 설계 및 제작하였다. 실제로 제작한 선형 전력 증폭기는 출력이 25W이고 Feedforward선형화 기법을 사용하여 FCC가 규정한 혼변조 왜곡 특성을 만족하도록 하였다. 선형 전력 증폭기의 출력별로 측정한 결과 1W(30dBm)에서 25W(44dBm)까지 14dB의 측정구간에서 선형화에 의한 혼변조 왜곡은 최저 10.51dBc부터 최고 19.01dBc까지 개선되었고, 최종 출력에서의 IMD 레벨은 최저 64.84dBc에서 최고 68.17dBc로 각각 나타났다. 이러한 특성은 PCS 기지국의 상용제품으로 충분히 사용할 수 있을 것으로 기대된다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권1호
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• pp.335-339
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• 2016

Background: The aim of this work was to investigate if serum and salivary auto-antibodies, isotypes IgG and IgM, against HER2 and MUC1 tandem repeat fragments could play a role in breast cancer screening. Materials and Methods: Our case-control study was conducted in breast cancer patients, in early stages (n=29), at the gynecology service, Maternity Souissi Hospital, Rabat, Morocco and healthy woman (n=31). Salivary and serum auto-antibodies against HER2 and MUC1 (tandem repeat) were assessed by enzyme-linked immunosorbent assay (ELISA) and compared between patients and healthy women using the Mann-Whitney U test. A P-value <0.05 was considered to be statistically significant. Results: Our data showed higher expression of all serum and salivary autoantibodies in patients as compared to healthy women p<0.05. However, serum IgM anti-MUC1 expression did not show a significant difference between cases and controls (p=0.79). Similarly, salivary IgG anti-HER2 expression did not differ (p=0.15). The correlation between the different isotypes of antibodies revealed that the highest correlation was between salivary IgG anti-HER2 and salivary IgG anti-MUC1(r=0.65). In fact, we have found in saliva the correlation between autoantibodies anti-MUC1 and anti-HER2 more important than in serum (r=0.59 and r=0. 55). However, the correlation between serum and saliva values for all antibodies was weak. Conclusions: Autoantibodies against HER2 and MUC1 may provide a useful approach in breast cancer screening when using both serum and saliva values.

• Asian Pacific Journal of Cancer Prevention
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• 제15권8호
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• pp.3805-3809
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• 2014

Background: In Mexico, breast cancer (BCa) is the leading type of cancer in women. Cytochrome P450 (CYP450) is a superfamily of major oxidative enzymes that metabolize carcinogens and many antineoplastic drugs. In addition, these enzymes have influence on tumor development and tumor response to therapy. In this report, we analyzed the protein expression in patients with BCa and in healthy women. Links with some clinic-pathological characteristic were also assessed. Materials and Methods: Immunohistochemical analyses were conducted on 48 sets of human breast tumors and normal breast tissues enrolled in Hospital Militar de Especialidades de la Mujer y Neonatologia and Hospital Central Militar, respectively, during the time period from 2010 to 2011. Informed consent was obtained from all participants. Statistical analysis was performed using ${\chi}^2$ or Fisher exact tests to estimate associations and the Mann Whitney U test for comparison of group means. Results: We found a significant CYP3A4 overexpression in BCa stroma and gland regions in comparison with healthy tissue. A significant association between protein expression with smoking, alcoholism and hormonal contraceptives use was also observed. Additionally, we observed estrogen receptor (ER) and progesterone receptor (PR) positive association in BCa. Conclusions: We suggest that CYP3A4 expression promotes BCa development and can be used in the prediction of tumor response to different treatments. One therapeutic approach may thus be to block CYP3A4 function.