• Neurospine
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• v.15 no.4
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• pp.323-328
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• 2018

The author reviews the various types of cervical fusion that are associated with instability of the craniovertebral junction. Assimilation of the atlas, C2-3 fusion, the Klippel-Feil abnormality, and pancervical fusion are amongst the more common types of bone abnormalities. It is conceptualised that these types of cervical fusion are not related to any kind of embryological dysgenesis or fault, but instead emerge due to longstanding muscle spasms of the neck in response to atlantoaxial instability. Such bone fusions could be secondary protective responses to longstanding atlantoaxial instability.

• Journal of the Korean Home Economics Association
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• v.35 no.4
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• pp.125-138
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• 1997

The purpose of this study was to explore the types of mother's language and literacy information as they collaborated to write a letter during a 10-minute session. Subjects of the study consisted of 60 mothers and their children 10 boys and 10 girls each at the age of 3,4 and 5 The mothers' teaching language was analyzed on the basis of hoffman(1987)'s study and the types of information thant mothers and children exchanged during writing letters was analyzed by Burns and Casbergue (1992)'s categories. Frequency percentages and χ2 tests were used to analyze the data. The resuls of this study were as follows. 1. The types of the mothers' teaching language from the most to the least were mother-initiated statements mother-initiated questions and mother's responses to child's efforts. There were significant differences according to children's age in mothers' language. In the mother-initiated questions request questions were used most frequently and followed by interrogation questions and invitation questions next. The statements initiated by mothers were directive comments informative comments supportive comments insistence comments and invitation comments in order. Mothers' responses to child's efforts were corrects/controls additional cues confirmation promotion and praise in order. In all three types of the teaching language significant promotion and praise in order. In all three types of the teaching language significant differences were found according to children's age. 2. The types of information about writing were spelling content off task/preparation mechanical conventions and conceptual meaning of writing in order. Significant differences were found according to children's age. In the age group of 4-and 5-year-olds the mothers exchanged more information about spelling than the mothers of 3-years-olds who frequently used information about content and off task or preparation of writing the letter.

• Genomics & Informatics
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• v.3 no.3
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• pp.63-67
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• 2005

Adaptive responses to diverse microbial pathogens might be limited in relatively few types. Host cell responses to pathogens are believed to be patterned or stereotyped along with species or class. We tried to compose the host response to Mycoplasma in terms of cellular gene expression. Although gene expression profile of two host HeLa and 293 cells were quite different each other, 30 genes were differentially expressed by mycoplasma infection in both of HeLa and 293 cells. Six of them (PR48, MADH4, MKPX, CRK, RBM7, NEK3) were related to cell cycle or proliferation. Another category of genes like IL1 HY1, KLRF1, TNFSF14, GBP1 were host defense to elicit immune responses. With this set of genes, we establish the prediction model for mycoplasma contamination.

• The Korean Journal of Nuclear Medicine
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• v.26 no.1
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• pp.8-13
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• 1992

Low doses of ionizing radiation from external or internal sources cause heterogeneous distribution of energy deposition events in the exposed biological system. With the cell being the individual element of the tissue system, the fraction of cells hit, the dose received by the hit, and the biological response of the cell to the dose received eventually determine the effect in tissue. The hit cell may experience detriment, such as change in its DNA leading to a malignant transformation, or it may derive benefit in terms of an adaptive response such as a temporary improvement of DNA repair or temporary prevention of effects from intracellular radicals through enhanced radical detoxification. These responses are protective also to toxic substances that are generated during normal metabolism. Within a multicellular system, the probability of detriment must be weighed against the probability of benefit through adaptive responses with protection against various toxic agents including those produced by normal metabolism. Because irradiation can principally induce both, detriment and adaptive responses, one type of affected cells may not be simply summed up at the expense of cells with other types of effects, in assessing risk to tissue. An inventory of various types of effects in the blood forming system of mammals, even with large ranges of uncertainty, uncovers the possibility of benefit to the system from exposure to low doses of low LET radiation. This experimental approach may complement epidemiological data on individuals exposed to low doses of ionizing radiation and may lead to a more rational appraisal of risk.

• The Korean Journal of Physiology and Pharmacology
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• v.13 no.3
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• pp.221-227
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• 2009

For successful restoration of visual function by a visual neural prosthesis such as retinal implant, electrical stimulation should evoke neural responses so that the informat.ion on visual input is properly represented. A stimulation strategy, which means a method for generating stimulation waveforms based on visual input, should be developed for this purpose. We proposed to use the decoding of visual input from retinal ganglion cell (RGC) responses for the evaluation of stimulus encoding strategy. This is based on the assumption that reliable encoding of visual information in RGC responses is required to enable successful visual perception. The main purpose of this study was to determine the influence of inter-dependence among stimulated RGCs activities on decoding accuracy. Light intensity variations were decoded from multiunit RGC spike trains using an optimal linear filter. More accurate decoding was possible when different types of RGCs were used together as input. Decoding accuracy was enhanced with independently firing RGCs compared to synchronously firing RGCs. This implies that stimulation of independently-firing RGCs and RGCs of different types may be beneficial for visual function restoration by retinal prosthesis.

• International Journal of Ocean System Engineering
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• v.3 no.4
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• pp.175-187
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• 2013

Moonpools are vertical wells in a floating body used onboard many types of vessels like Exploration and drilling vessels, Production barges, Cable-laying vessels, Rock dumping vessels, Research and offshore support vessels. Moonpool gives passage to underwater activities for different types of ships as per their mission requirements. It is observed that inside a moonpool considerable relative motions may occur, depending on shape, depth of the moonpool and on the frequency range of the waves to which the ship is exposed. The vessel responses are entirely different in zero and non-zero Froude number. Former situation is paid attention in this study as the mission requirement of the platform is to be in the particular location for long period of operation. It is well known that there are two modes of responses depending on the shape of the moonpool viz., piston mode for square shape and sloshing mode for rectangular shapes with different aspect ratios of opening like 1:1.5 and 1:2 ratios. Circular shaped moonpool is also tested for measuring the responses. The vessel moored using heavy lines are modelled and tested in the wave basin. The pretensions of the lines are varied by altering the touchdown points and the dynamic tensions on the lines are measured. The different modes of oscillations of water column are measured using wave gauge and the vessel response at a particular situation is determined. RAOs calculated for various situations provide better insight to the designer.

• Research in Mathematical Education
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• v.12 no.1
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• pp.49-66
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• 2008

In this paper we present a cognitive developmental analysis of the arithmetic mean concept. This analysis leads us to a hierarchical classification at different levels of understanding of the responses of 227 students to a questionnaire which combines open-ended and multiple-choice questions. The SOLO theoretical framework is used for this analysis and we find five levels of students' responses. These responses confirm different types of difficulties encountered by students regarding their conceptualization of the arithmetic mean. Also we have observed that there are no significant differences between secondary school and university students' responses.

• Journal of the Korean Society of Costume
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• v.29
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• pp.39-52
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• 1996

The purpose. of this study were to identify the types of consumer affective responses to investigate the attitude formation process on the apparel advertising and to identify the differences among related variables according to the sensation seeking and the brand famili-arity. The result of this study were as follows: 1. The consumer affective responses on ap-parel dvertising was composed of six dimensions; Upbeat feeling Negative feeling Warm feeling Sensual feeling Emotional feel-ing and Uninvolved feeling. 2. The related variables to consumer responses on apparel advertising were signifi-cant differences according to the sensation seeking and the brand familiarity. 3. The main causal course on the apparel ad-vertising was the consumer affective responselongrightarrowthe advertising attitudelongrightarrowthe brand evalu-ationlongrightarrowthe brand attitudelongrightarrowthe purchase in-tention. Also there were differences in atti-tude formation process according to the con-sumer affective respeonses.

• IMMUNE NETWORK
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• v.24 no.1
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• pp.5.1-5.19
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• 2024

The key role of T cells in cancer immunotherapy is well established and is highlighted by the remarkable capacity of Ab-mediated checkpoint blockade to overcome T-cell exhaustion and amplify anti-tumor responses. However, total or partial tumor remission following checkpoint blockade is still limited to only a few types of tumors. Hence, concerted attempts are being made to devise new methods for improving tumor immunity. Currently, much attention is being focused on therapy with IL-2. This cytokine is a powerful growth factor for T cells and optimises their effector functions. When used at therapeutic doses for cancer treatment, however, IL-2 is highly toxic. Nevertheless, recent work has shown that modifying the structure or presentation of IL-2 can reduce toxicity and lead to effective anti-tumor responses in synergy with checkpoint blockade. Here, we review the complex interaction of IL-2 with T cells: first during normal homeostasis, then during responses to pathogens, and finally in anti-tumor responses.

• Ocean Systems Engineering
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• v.3 no.2
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• pp.137-147
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• 2013

Moonpools are vertical wells in a floating body used onboard many types of vessels like cable-laying vessels and offshore support vessels. Moonpool gives passage to underwater activities for different types of ships as per their mission requirements. It is observed that inside a moonpool considerable relative motions may occur, depending on shape, depth of the moonpool and on the frequency range of the waves to which the ship is exposed. The vessel responses are entirely different in zero and non-zero Froude number. Former situation is paid attention in this study as the mission requirement of the platform is to be in the particular location for long period of operation. It is well known that there are two modes of responses depending on the shape of the moonpool viz., piston mode for square shape and sloshing mode for rectangular shapes with different aspect ratios of opening like 1:1.5 and 1:2 ratios. Circular shaped moonpool is also tested for measuring the responses. The vessel moored using heavy lines are modeled and tested in the wave basin. The moored lines are provided with pre-tension and the dynamic tensions on the lines are measured. The different modes of oscillations of water column are measured using wave gauge and the vessel response at a particular situation is determined. RAOs determined for various situations provide better insight to the designer. The experiments done in the wave basin may also be compared with a software package meant for handling moored floating bodies.