• The Journal of Korean Physical Therapy
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• v.22 no.3
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• pp.55-59
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• 2010

Purpose: This study was designed to investigate the effect of a water exercise program on the pennation angle of the lower-limb muscle in women in their 20s. Methods: Ten female subjects were randomly divided into two groups, with 5 subjects exercising in water 0.7 m deep and 5 subjects exercising in water 1.4 m deep. They did the water exercising program for 40 minute per day, 3 days per week, for total 6 weeks. We measured the pennation angle of lower-limb muscle using ultrasonography. All measurements for each group were performed at pre-training and after 6 weeks of training. Results: The pennation angle was compared before and after the water exercise period for each group, and statistically significant changes within each group in measurements of the rectus femoris and tibialis anterior (p<0.05). However, there was no significant difference in muscle architecture by water depth (p>0.05) between the two groups. Conclusion: These results show that the pennation angle of the lower-limb muscle of women in their 20s changed after 6 weeks of participating in a water exercise program, but these changes were not dependent on the depth of the water in which the exercises were performed.

• Korean Journal of Adult Nursing
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• v.28 no.4
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• pp.436-446
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• 2016

Purpose: The purpose of this study was to identify the effect of auricular acupressure on pruritus and fatigue in hemodialysis patients. Methods: The study design was a randomized control group pre-post test. Initially, forty-four patients were randomly assigned to one of two groups. There was a loss of three participants assigned to the treatment group. The period of data collection was from December 2014 to March 2015. Both groups completed a pre-test. The treatment group received auricular acupressure once a week for ten weeks. Data were collected from the treatment group at two time periods: five weeks and ten weeks following initiation of the treatment protocol. Data were collected from the control group at week 5 and week 10. Data analysis was performed using IBM SPSS Statistics 21.0 program, specifically with the independent t-test and the Repeated Measures of ANOVA. Results: Auricular acupressure was effective in reducing pruritus (F=13.93, p<.001) and fatigue (F=18.33, p<.001). Conclusion: Auricular acupressure is a non-invasive simple method that can be used for the relief of symptoms reported by hemodialysis patients. This treatment modality could be used in several clinical areas.

• Korean Journal of Applied Biomechanics
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• v.24 no.3
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• pp.309-315
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• 2014

The aim of the present study was to investigate the effects of 6-week wrist resistance training on wrist torque control. Nineteen subjects were randomly assigned to either the wrist training group (n=9) or the control group (n=10). The training group performed wrist exercises for six directions (flexion, extension, pronation, supination, radial deviation, and ulnar deviation) while the control group did not. Testing for the isometric torque control error, one-repetition maximum (1-RM) strength, and isokinetic maximum torque (angular velocity of $60^{\circ}/s$ wrist movements) were conducted before and after six weeks of resistance training and after every two-week interval of training. The wrist training group showed significant decreases in isometric torque control error in all six directions after the 2-week resistance training, while the control group did not show significant increase or decrease. The training group showed significant increases in the maximum strength in all six directions assessed by 1-RM strength and isokinetic strength tests after the 4-week resistance training, while the control group did not show any statistically significant changes. This study shows that motor control ability significantly improves within the first two weeks of resistance training, while the wrist strength significantly improves within the first four weeks of resistance training in wrist training group compared to the control.

• Journal of the Korean Society of Tobacco Science
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• v.7 no.1
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• pp.7-13
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• 1985

Effect of the two PVY strains(PVY-VB and PVY-VN) on yield and chemical constituents of tobacco plants was determined in roar. NC2326 and Burley 21. The virus was inoculated 6 and 8 weeks after transplanting, respectively. The strains and time of inoculation were most critical factors for yield reduction. The greatest reduction was caused by the necrotic strain (PVY-VN) inoculated 6 weeks after transplanting, accounting for the loss of 40% in var. NC2326 and of 45% in var.. Burley21. When inoculated 8 weeks after transplanting with the necrotic strain, only 17% reduction was recorded in roar. Burley21, but no reduction occurred in roar. NC2326. Generally less reduction was caused by the PVY-VB strain, ranging 12-16% depending on the time of inoculation and/or variety. Compared to healthy tobacco, PVY infected tobacco contained higher concentrations of total nitrogen, protein nitrogen, nitrate nitrogen, and lower total sugar in cured leaf of roar. NC2326. Total alkaloid, P, Mg, Ca, and K levels were not altered. In var. Burley21, protein nitrogen and nitrate nitrogen increased, but other chemical components were not changed. Necrotic strain-infected tobacco with a severe symptom had higher nitrogen than did mild strain-infected tobacco.

• Journal of The Korean Society of Integrative Medicine
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• v.8 no.2
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• pp.41-51
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• 2020

Purpose : The purpose of this study was to determine the effect of scapulothoracic exercise and thoracic mobilization on shoulder pain and function in individulas with shoulder partial- thickness rotator cuff tear. Methods : Forty-five subjects were recruited and randomly divided into 3 groups of 15 subjects each : Scapulothoracic exercise with Thoracic mobilization (STwTM), Scapulothoracic exercise (ST), and Thoracic mobilization (TM) groups. All subjects were assessed for pain and disability of shoulder, thoracic angle base on the Shoulder Pain and Disability Index (SPADI) and Thoracic kyphosis assessment (TKA) using Baseline Bubble Inclinometer. All groups performed 50 minutes of the intervention twice a week for a total of six weeks. These tests were evaluated Three times : prior to the start of the intervention, after three weeks and, after six weeks had passed. Results : The SPADI score showed that pain and dysfunction in the STwTM group decreased compared to those in the other two groups. The TKA score showed a decrease over time in the ST, TM, and STwTM groups, in increasing order. However, the TKA score decreased significantly in the STwTM group compared to that in the oher two groups. Conclusion : ST and TM are effective in improving pain and dysfunction in patients. However, STwTM may be more effective for patients.

• The Journal of Korean Physical Therapy
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• v.32 no.2
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• pp.126-131
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• 2020

Purpose: The purpose of this study was to compare the change in pain, Neck Disability Index score, and the craniovertebral angle by performing scapular correction exercise or general neck exercise for five weeks in participants with mechanical neck pain. Methods: A total of 31 participants were randomly assigned between the scapular correction exercise and the general neck exercise groups, and all participants performed intervention for 40 minutes each, three times a week for five weeks The effects were evaluated by measuring the Visual Analog Scale score, the Neck Disability Index score, and the craniovertebral angle, before and after the intervention. Independent t-tests were used to compare differences between two groups, and to compare differences between pre- and post-intervention, paired t-tests were used. Results: As measured before and after the intervention, the scapular correction exercise group showed significant improvement in all variables (p<0.05), while the general neck exercise group improved only in the neck disability index score. The differences between the two groups revealed further improvement in the scapular correction exercise group compared to the general neck exercise group (p<0.05). Conclusion: We found that five weeks of the scapular correction exercise to modify the position and movements of the scapula is clinically an important treatment tool for recovery from chronic mechanical neck pain symptoms and restoration of proper neck function.

• Journal of Nutrition and Health
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• v.25 no.2
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• pp.116-122
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• 1992

This study determined hepatic microsomal lipid peroxide values glucose 6-phosphatase NA-DPH-cytochrome P450 reductase and cytosolic glutathione S-transferase activites to examine the effects of methyl group deficiency on hepatic lipid peroxidation in rats treated with diethylni-trosamine(DEN) and 2-acetylamionfluorene(AAF) Weanling sprague Dawley male rats were fed the diet with methyl group supplemented or deficient. Two weeks after feeding rate were injected with a single of 200mg/kg body weight DEN intraperitoneally and after four weeks 0.02% AAF containing diets were fed for two weeks. Animals were sacrificed at 6th week. Microsomal lipid peroxide values were tended to increase in methyl group deficiency(MD). Especially in case of carcinogen tratments lipid peroxide values were increased significantly in MD. Microsomal glucose 6-phophatase activities were decreased by MD and carcinogens and in MD with carcinogen group (MD+C) the enzyme activites were the lowest Glucose 6-phosphatase activities were negatively correlated with lipid peroxidation. Microsomal NADPH-cytochrome P450 reductase activities were the highest in MD+C and correlated positively with lipid peroxidation. Cytosolic glutathione S-transferase activities were the highest in MD+C Methyl group deficiency induces lipid peroxidation especially in case of being exposed to carcinogens. Therefore the results suggest that lipid peroxidation may be one of the meachanisms of carcinogensis by methyl group deficiency.

• Korean Journal of Veterinary Research
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• v.61 no.1
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• pp.9.1-9.6
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• 2021

Factors such as location, volume, and the type of neoplasm complicate achieving tumor control. Electrochemotherapy (ECT) is a supplementary treatment for inoperable neoplasms in veterinary patients. Three dogs were diagnosed with a tumor. Two were squamous cell carcinoma (SCC), and the other was liposarcoma, each with a single tumor with the size range of 1 to 5 cm. The tumor locations were the cervical, oral, and abdominal cavity. ECT was selected as a treatment. Bleomycin was injected intratumorally at the dose of 0.5 to 1.0 mg/㎤. Five minutes after the injection, electric pulses applied in a sequence of eight pulses lasting 100 μsec each, were delivered in 1,000 V/cm. An evaluation was performed after 1 week, and the next session was administered 2 weeks later. In a patient with oral SCC, the tumor was in partial remission after two sessions of ECT. Another patient with SCC on her neck was showed complete remission after 2 weeks of ECT administration. A third patient showed stable disease for 8 weeks. Complications were mild and transient and included skin necrosis, edema, local pain, and gait disturbance. ECT is a valid adjuvant, especially for inoperable, cutaneous, or accessible intra-abdominal tumors.

• Journal of Periodontal and Implant Science
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• v.29 no.3
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• pp.715-724
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• 1999

The purpose of this study was to approve the possibility of clinical application of selftesting technique to confirm the cleanness status of the tooth surface after mechanical toothbrushing. Thirty-two periodontal patients who did not compromise any other systemic diseases were divided into two groups. Control group was instructed only the Bass method for toothbrushing, and then experimental group was demonstrated the Bass method and self-testing technique respectively for plaque control during this experiment. Selftesting technique is composed the comparison of roughness of the labial surface of maxillary central incisor and other toothsurface with touch sense using the tip of tongue. Plaque score and Gingival index were measured as clinical parameters at baseline and 1, 2 and 4 weeks after scaling and root planing. The results were as follows ; 1. Plaque scores and gingival index of 1, 2, and 4 weeks of two groups were statistically significant differences when compared with baseline value (p<0.05). 2. Plaque scores and gingival index of baseline and 1 week between two groups were not significant differences (p<0.05). 3. Plaque scores and gingival index of 2 and 4 weeks of test group were statistically significant difference when compared with control group (p<0.05). From the above results, self-testing technique which decides necessity of additional toothbrushing when tongue tip of subjects touch the maxillary molar buccal surfaces and mandibular molar lingual surfaces nd compares with maxillary anterior labial surfaces after toothbrushing appeared to effect the motivation of subjects. This study suggests that self-testing technique for cleanness after toothbrushing should be effect on the maintenance of oral hygiene when it is applied to clinical practice.

• Journal of Pharmaceutical Investigation
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• v.39 no.1
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• pp.37-41
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• 2009

The purpose of this study was to compare the efficacy of Lorelin Depot $Injection^{(R)}$ (Dongkook Pharm. Co., LTD) with Lucrin Depot $Injection^{(R)}$ (Abbott) by measuring serum testosterone level in rats. Leuprorelin (leuprolide acetate), which is an active compound for the two formulations, is an LHRH analogue that is used for the treatment of a wide range of sex hormone-related disorders including advanced prostatic cancer, endometriosis and precocious puberty. Lorelin Depot $Injection^{(R)}$ is a micro-encapsulated formulation to suppress testosterone level by releasing leuprorelin continuously for four weeks with a single subcutaneous injection. The comparison study of the efficacy was performed during four weeks, and serum testosterone levels were monitored in the two formulations. The mean serum testosterone levels from the formulations were decreased to that of the castrate range (50 ng/dL or less) after three days after the initial depot injection, and the concentration were remained throughout four weeks' period. There were no significant differences in the $AUC_{0-3day}$ of testosterone and testosterone levels at 3, 7, 14, 21 and 28 days between the two formulations. These results indicate that the two formulations, Lorelin Depot $Injection^{(R)}$ and Lucrin Depot $Injection^{(R)}$, are bioequivalent in terms of the serum testosterone level in rats.