• 조명전기설비학회논문지
• /
• 제23권10호
• /
• pp.14-20
• /
• 2009

전력 계통 내에서 발생하는 과도한 고장전류의 억제를 위한 가장 이상적인 방안은 초전도 한류기이다. 초전도 한류기의 전력계통 적용을 위해 본 논문에서는 전력계통 내에서 발생하는 1선, 2선, 3선 지락사고를 모의하여 매트릭스형 초전도 한류기의 동작 특성 및 소비전력을 분석하였다. 모든 지락사고에 대해 매트릭스형 초전도 한류기는 사고 초기에는 85[%] 이상, 1주기 이후에는 95[%] 이상 고장전류를 제한시킬 수 있다는 것을 확인하였다. 또한 초전도 소자간의 임계특성의 차이를 줄여줌으로써 소비전력이 균등해진다는 것을 확인하였다.

• 한국정보과학회논문지:데이타베이스
• /
• 제34권6호
• /
• pp.518-527
• /
• 2007

RDF 문서들은 빈번히 갱신이 발생하므로 RDF 문서간의 변경부분을 찾아내는 것은 중요한 관심사가 된다. RDF 문서 내에 공노드가 존재할 경우 변경부분을 탐지해내려면 공노드간의 매칭을 지원하는 기법이 필요하다. RDF 문서에서 공노드는 내포된 형태로 존재하며 실제 사용되는 RDF 문서 대부분이 공노드를 포함하고 있다. RDF 문서를 그래프로 모델링하면 하나의 문서는 여러 개의 트리로 나누어진다. 따라서 문서간의 변경탐지는 동일한 루트를 가지는 트리간의 최소 비용 매칭 문제로 생각할 수 있다. 본 논문에서는 공노드에 대한 레이블링 기법을 기용하여 내포된 공노드를 포함한 RDF문서의 변경탐지 기법을 제안한다. 또한 공노드가 아닌 일반 트리플들의 비교에 있어서도 효율성을 높이는 술어 그룹화와 분할 기법을 제안한다. 실험을 통해 제안한 기법이 기존의 방법보다 더 정확하며 효율적임을 보였다.

• Nuclear Engineering and Technology
• /
• 제21권4호
• /
• pp.277-286
• /
• 1989

PWR 핵연료의 연소도측정은 삼중스파이크(U-233. Pu-242, Nd-150)를 사용한 동위원소 희석 질량분석법으로 U, PU, Nd-148 및 Nd-(145+146)을 정량하여 수행하였다. 이 방법은 먼저 두개의 연속적 이온교환수지 분리과정을 거친다. Pu는 첫번째 음이온 교환수지 분리관(Dowex AG 1 X 8)으로부터 12 M HCl-0.1 M HI 혼합용액으로 분리하고 이어서 0.1 M HCl로 U을 분리하였다. Nd은 질산-메탄올 용리액으로 두번째 음이온 교환수지분리관(Dowex AG 1 X 4) 상에서 분리하였다. 각 부분을 열이온화질량분석법으로 각각의 동위원소비를 측정하였다. Nd-148과 Nd-(145+146) 방법 사이의 차이는 평균 2.07%로 나타났다. 이 결과를 U과 Pu동위원소를 이용한 무거운 원소방법 및 Cs-137의 파괴 감마분광측정법과 비교하였다. 연소도에 대한 U과 Pu의 동위원소 조성의존도와 동위원소사이의 상관관계를 그래프로서 설명하였다.

• 농업과학연구
• /
• 제44권2호
• /
• pp.145-180
• /
• 2017

Alternanthera mosaic virus (AltMV) is a member of the genus Potexvirus which has been known for less than twenty years, and has been detected in Australasia, Europe, North and South America, and Asia. The natural host range to date includes species in at least twenty-four taxonomically diverse plant families, with species in at least four other families known to be infected experimentally. AltMV has been shown to differ from Potato virus X (PVX), the type member of the genus Potexvirus, in a number of ways, including the subcellular localization of the Triple Gene Block 3 (TGB3) protein and apparent absence of interactions between TGB3 and TGB2. Differences between AltMV variants have allowed identification of viral determinants of pathogenicity, and identification of residues involved in interactions with host proteins. Infectious clones of AltMV differing significantly in symptom severity and efficiency of RNA silencing suppression have been produced, suitable either for high level protein expression (with efficient RNA silencing suppression) or for Virus-Induced Gene Silencing (VIGS; with weaker RNA silencing suppression), demonstrating a range of utility not available with most other plant viral vectors. The difference in silencing suppression efficiency was shown to be due to a single amino acid residue substitution in TGB1, and to differences in subcellular localization of TGB1 to the nucleus and nucleolus. The current state of knowledge of AltMV biology, including host range, strain differentiation, host interactions, and utility as a plant viral vector for both protein expression and VIGS are summarized.

• 한국임상약학회지
• /
• 제30권3호
• /
• pp.149-160
• /
• 2020

Background: Basiliximab is used as an alternative to tacrolimus in patients with decreased renal function. However, studies on basiliximab as a maintenance immunosuppressant, particularly in patients with lung transplantation, are limited. Therefore, here, we investigated the efficacy and safety of basiliximab in patients with lung transplantation. Methods: Adult patients with acute kidney injury (AKI) who received lung transplantation at a single general hospital between July 1, 2014 and June 30, 2018, were selected and classified in tacrolimus and basiliximab groups. Both groups received a triple-drug regimen (tacrolimus, mycophenolate mofetil, and steroids). However, tacrolimus was discontinued in the basiliximab group when AKI occurred, and two or more repeat basiliximab doses were administered within 3 months after transplantation. The electronic medical records were analyzed retrospectively. Results: Of the 85 patients who met the selection criteria, 61 and 24 were assigned to the tacrolimus and basiliximab groups, respectively. Significant improvement in renal function was observed in the basiliximab group (p <0.001). However, there were no differences in acute and chronic rejection rates in both the groups. No difference was observed in the incidence rate of complications between the groups, except for chronic kidney disease, which showed higher incidence in the basiliximab group (25.0% vs. 4.9%; p =0.013). Conclusions: We suggest the use of basiliximab as an immunosuppressant alternative to tacrolimus in patients with acute renal failure after lung transplantation. Basiliximab demonstrated effectiveness as an immunosuppressant and improved renal function. Therefore, basiliximab can be used in patients with decreased renal function.

• Preventive Nutrition and Food Science
• /
• 제8권4호
• /
• pp.301-305
• /
• 2003

This study was conducted to develop an HPLC method for determining vitamin B$_{12}$ in fortified foods which has typically been determined by microbiological assays according to AOAC and Korean Food Code approved methods. Vitamin B$_{12}$ (cyanocobalamin) was determined by reversed-phase HPLC with a triple column and UV/VIS dectector (550 nm) using the column switching technique after extraction with 5 mM potassium phosphate solution by sonication without a clean-up procedure. The recovery of spiked samples and limit of detection (LOD) by HPLC were 78.6 ∼107.5 % and 2 ppb ($\mu\textrm{g}$/kg), respectively. The LOD of the microbiological assay (MBA) was much lower than that of HPLC. The concentrations of vitamin B$_{12}$ analyzed in all tested samples (n=12) confirmed compliance with declared label claims. The range of recovery ratio by the HPLC method when compared to the microbiological assay was 76.2 ∼140.0 %. There was not significant difference between the HPLC and MBA methods (p < 0.01) with r=0.9791 and linear regression y=0.9923x-0.04. The HPLC method for determining vitamin B$_{12}$ using the column-switching technique appears to be suitable for determining vitamin B$_{12}$ concentrations above 1 $\mu\textrm{g}$/100 g in fortified foods.ied foods.

• Journal of the Optical Society of Korea
• /
• 제18권3호
• /
• pp.261-273
• /
• 2014

In this paper, metal insulator metal (MIM) plasmonic slot cavity narrow band-pass filters (NBPFs) are studied. The metal and dielectric of the structures are silver (Ag) and air, respectively. To improve the quality factor and attenuation range, two novel NBPFs based on tapered structures and double cavity systems are proposed and numerically analyzed by using the two-dimensional (2-D) finite difference time domain (FDTD) method. The impact of different parameters on the transmission spectrum is scrutinized. We have shown that increasing the cavities' lengths increases the resonance wavelength in a linear relationship, and also increases the quality factor, and simultaneously the attenuation of the wave transmitted through the cavities. Furthermore, increasing the slope of tapers of the input and output waveguides decreases attenuation of the wave transmitted through the waveguide, but simultaneously decreases the quality factor, hence there should be a trade-off between loss and quality factor. However, the idea of adding tapers to the waveguides' discontinuities of the simple structure helps us to improve the device total performance, such as quality factor for the single cavity and attenuation range for the double cavity. According to the proposed NBPFs, two, three, and four-port power splitters functioning at 1320 nm and novel ultra-compact two-wavelength and triple-wavelength demultiplexers in the range of 1300-1550 nm are proposed and the impacts of different parameters on their performances are numerically investigated. The idea of using tapered waveguides at the structure discontinuities facilitates the design of ultra-compact demultiplexers and splitters.

• 대한금속재료학회지
• /
• 제48권4호
• /
• pp.289-296
• /
• 2010

The effects of heat input and different microstructureswere investigated on the tensile-shear properties of an arc-brazed joint of theferritic stainless steel 429EM using a Cu-Si insert alloy. The brazing speed was fixed at 800 mm/min whilethe brazing current varied from 80 to 120A. For abrazing current lower than 100A, fracturing occurred at the joint root in the direction perpendicular to the tensile load. As the brazing current increased to 120A, fracturing occurred at the base metal or the joint root. The joint and the base metal had very similar yield and tensile load values. However, the amount of elongation was decreased considerably compared to when the base metal was used. The fracturing began at the triple point of the root part and was classified into three types. The difference in the tensile-shear properties was closely related to the three fracture types.

• Mass Spectrometry Letters
• /
• 제12권2호
• /
• pp.53-58
• /
• 2021

Previous in vitro studies have demonstrated that ginsenoside Rc inhibits UGT1A9, but there are no available data to indicate that ginsenoside Rc inhibits UGT1A9 in vivo. The effect of single and repeated intravenous injection of ginsenoside Rc was evaluated on the pharmacokinetics of mycophenolic acid. After injection of ginsenoside Rc (5 mg/kg for one day or 3 mg/kg for five days), 2-mg mycophenolic acid was intravenously injected, and the pharmacokinetics of mycophenolic acid and mycophenolic acid-β-glucuronide were determined. Concentrations of mycophenolic acid and its metabolite from rat plasma were analyzed using a liquid chromatography-triple quadrupole mass spectrometry. Single or repeated pretreatment with ginsenoside Rc had no significant effects on the pharmacokinetics of mycophenolic acid (P > 0.05): The mean difference in maximum plasma concentration (C_max) and area under the concentration-time curve (AUC_inf) were within 0.83- and 0.62-fold, respectively, compared with those in the absence of the ginsenoside Rc. These results indicate that ginsenoside Rc has a negligible effect on the disposition of mycophenolic acid in vivo despite in vitro findings indicating that ginsenoside Rc is a selective UGT1A9 inhibitor. As a result, ginsenoside Rc has little possibility of interacting with drugs that are metabolized by UGT1A9, including mycophenolic acid.

• Journal of Dental Anesthesia and Pain Medicine
• /
• 제22권5호
• /
• pp.387-394
• /
• 2022

Background: Dental pain management is an important aspect of patient management in pediatric dentistry. Articaine is considered the most successful anesthetic agent for infiltration anesthesia. Buffered articaine has been observed to have faster onset and longer duration of action with less pain on injection. The aim of this study was to evaluate and compare pain on injection, onset of action, and pain during extraction using buffered (using Sodium bicarbonate (NaHCO₃)) and non-buffered 4% articaine (with 1:100000 adrenaline) infiltrations for primary maxillary molar extractions in 4-10-year-old children. Methods: Seventy children who required extraction of maxillary primary molars were enrolled in this triple-blind randomized study. Children undergoing extraction were randomly divided into two groups, with 35 in each group. The study group was the buffered articaine group; the control group was the non-buffered articaine group. Buccal and palatal infiltrations were administered with either buffered or non-buffered articaine. Subjective evaluation was done for pain on injection, pain during extraction using Wong-Baker Faces Pain Rating Scale (WBFPR) and onset of anesthesia in seconds. Pain on injection, pain during extraction were objectively evaluated using Sound Eye Motor (SEM) scale and onset of anesthesia was also evaluated objectively by pricking with sharp dental probe. Results: The outcome was, significantly less pain on injection and significantly faster onset of anesthesia with significantly less pain during extraction for both subjective and objective evaluations in the buffered articaine group. Subgroup analysis was also performed and it showed variable results, with only significant difference for WBFPR scores in age subgroup 4-7 years for palatal infiltration. Conclusion: Less pain on injection, faster onset of anesthesia, and less pain during extraction were observed when buffered articaine was used for maxillary primary molar extraction.