• 대한화학회지
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• 제54권6호
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• pp.731-736
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• 2010

5-Aryl-3-($\beta$-D-glucopyranosylthio)-1,2,4-triazole 화합물들을 합성하였으며, 합성한 화합물들에 대한 항균활성시험을 수행하였다.

• Bulletin of the Korean Chemical Society
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• 제11권5호
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• pp.383-386
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• 1990

We have synthesized several bicyclic heteroaromatic compounds with bridgehead nitrogen from N-amine salts of heteroaromatic amines. 2-Amino and 2-unsubstituted thiazolo[3,2-b][l,2,4]triazole derivatives 2a-b were prepared by the cyclization reaction from N-amine salts of aminothiazole-5-yl(N-methoxyimino)acetate with cyanogen bromide and formamidine acetic acid salt, respectively. 2-Methylthiazolo[3,2-b][1,2,4]triazole 2c was obtained from N-acetylated N-amine salt of aminothiazole-5-yl(N-methoxyimino)acetate by the cyclization reaction in the presence of polyphosphoric acid (PPA). 2-Substituted and 2-unsubstituted thiazole[3,2-b][1,2,4]triazole derivatives 2a-c were coupled with 7-aminocephalosporanic acid (7-ACA). Coupled cephalosporin derivatives 1a-c did not have good antibacterial activities in vitro.

• 한국자기공명학회논문지
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• 제27권2호
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• pp.10-15
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• 2023

The Strain-Promoted Azide-Alkyne Cycloaddition (SPAAC) is a powerful method for synthesizing triazoles, even under physiological conditions, without a copper catalyst. This technique provides an efficient means for everyone to synthesize complex triazole derivatives rapidly. In order to investigate the configuration of triazole derivatives using bicyclo[6.1.0.]-nonyne (BCN) and chiral azide, it is necessary to employ the 2D NMR. Both 1D and 2D NMR (COSY, HSQC, ¹⁵N HMBC) are used to analyze the complex triazole product containing cyclooctyne, a diastereomeric product. The stereometric difference of the proton bonded to the same carbon is determined through the HSQC assignment. The intriguing splitting pattern of carbon resonances also reveals their diastereomeric configuration and will aid in further research based on physiological knowledge.

• Bulletin of the Korean Chemical Society
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• 제29권12호
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• pp.2517-2520
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• 2008

• The Plant Pathology Journal
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• 제33권6호
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• pp.589-596
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• 2017

Chemical management of dollar spot in turf may lead to the development of Sclerotinia homoeocarpa populations with reduced fungicide sensitivity. The objective of this study was to investigate resistance of S. homoeocarpa isolates to triazole fungicides and to test cross-resistance among three triazole fungicides. A total of 66 isolates of S. homoeocarpa were collected from 15 golf courses across Korea, and tested via in vitro sensitivity assay against hexaconazole, propiconazole and tebuconazole. $EC_{50}$ values of the isolates to these fungicides were distributed in the range of $0.001-1.1\;a.\;i.\;{\mu}g\;ml^{-1}$. Based on the $EC_{50}$ values, twelve representative strains were selected as sensitive isolates including control and insensitive isolates with respect to each fungicide. At a concentration of $0.1\;a.\;i.\;{\mu}g\;ml^{-1}$ for all fungicides, the selected strains were distinguished as sensitive or resistant isolates with the mycelial growth inhibition rate of 50% as the criterion. The $EC_{50}$ values of resistant strains exposed to hexaconazole, propiconazole and tebuconazole were 20-50 times, 50-70 times, and 77 times greater, respectively, than that of the control strains. Two isolates of S. homoeocarpa S0-41 and Sh14-2-1 showed sensitivity toward all the fungicides used, while two other isolates Sh7-5-1 and Sh2-1-1 showed resistance to all fungicides. Each isolate showed similar resistance to the three types of triazole fungicides, whereby cross-resistance of isolates was confirmed in the present study; all three triazole fungicide combinations displayed significant correlation coefficients equivalent to or greater than 0.8.

• 생물환경조절학회지
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• 제16권3호
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• pp.205-209
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• 2007

공정육묘의 양질묘 생산을 목적으로 여름철 고온기 및 장마기, 겨울철 약광 등 환경조건의 영향을 받지 않고 묘의 도장을 억제하면서도 안정적으로 생육 및 수량을 확보할 수 있는 triazole계 생장조절제의 약제 선발, 처리량 및 처리시기를 구명하고자 수행하였다. 토마토 플러그묘에 트리아졸계 생장조절제 처리시 관행구에 비하여 초장 및 엽면적이 억제되었으며, 처리시기가 빠르고 처리량이 많을수록 억제효과가 컸다. 생육의 회복정도는 Hexaconazole 처리에서 정식 4주후 안정적으로 회복되었다. Diniconazole과 hexaconazole처리시 1화방의 착과높이가 낮아졌으며, 화방별 착과수는 관행구에 비하여 차이가 없었다.

• Bulletin of the Korean Chemical Society
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• 제29권8호
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• pp.1617-1620
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• 2008

• Bulletin of the Korean Chemical Society
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• 제27권10호
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• pp.1677-1680
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• 2006

• Bulletin of the Korean Chemical Society
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• 제30권10호
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• pp.2467-2470
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• 2009

• Bulletin of the Korean Chemical Society
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• 제29권2호
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• pp.511-514
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• 2008