• KSBB Journal
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• v.24 no.1
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• pp.25-29
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• 2009

Ceramide is important not only for the maintenance of the barrier function of the skin but also for the water-binding capacity of the stratum corneum. Though the effectiveness of ceramide is not understood fully, ceramide has become a widely used ingredient in cosmetic and pharmaceutical industries. However, ceramide production from Saccharomyces cerevisiae has not been widely studied and the quantity are very low. Gene deletion in the cell is used frequently to investigate the function of gene and verification research of drug target. Specially, deletion mutant library is useful for a large amount functional analysis of gene. In this study, deletion mutants of genes on the metabolic pathway of ceramide synthesis in S. cerevisiae were grown in a batch culture and the cellular content of ceramide was measured. The ceramide content was highest in ${\triangle}$ydc1 mutant and 6 mg ceramide/g cell was obtained.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.6C
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• pp.751-762
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• 2004

In this paper, we propose the method to derive new GRM(Generalized Reed-Muller) coefficients for each 2$^n$ polarities using Triangle cell. As the existing methods to generate GRM coefficients, there are Green's method to operate transform matrix with a given RM coefficient and Besslich's method to get other polarities using basic transfer matrices repeatedly. In this paper, Triangle cell is defined so as to obtain GRM coefficients efficiently. After arranging 2$^n$ given RM coefficients of a first row of Triangle cell, sequence modulo sum is peformed in parallel to low column by a fixed numerical formula. To prove the efficiency of proposed arithmetic method, it is compared with Besslich’s method. As the compared result, to calculate GRM coefficients of all polarities to n input variables, Besslich’s method needs 2$^n$$^{-1}$ ${\times}$(2$^n$-1) two-input Ex-ORs and the proposed method needs 2${\times}$(the number of Ex-ORs for n-1 variables)+3$^n$$^{-1}$ for the same system complexity - (lo $g_2$$^n$) $T_{X}$./.

• Anatomy and Cell Biology
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• v.56 no.2
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• pp.205-210
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• 2023

Left coronary artery divides into anterior interventricular branch and circumflex branch. As both the arteries run in their corresponding grooves, an arteriovenous trigone is formed between conus arteriosus and left auricle called triangle of Brocq and Mouchet. The triangle base is formed by great cardiac vein. This study aims to describe the frequency of triangle and its type and relationship between various boundaries and content of triangle and to supplement the existing knowledge of clinicians. This observational and descriptive study was conducted on 40 formalin fixed cadaveric hearts in department of anatomy, Kalpana chawla government medical college. The triangle was found in 92.5% of specimen with most common type being closed (51.3%) which is followed by inferiorly open in 35.1%, superiorly open in 8.1% and completely open in 5.4% hearts. Most frequent content of triangle was median artery followed by diagonal branches of anterior interventricular and circumflex branches. The mean area of the triangle was 246.3 mm². Relationship of vein with two arterial branches was either superficial or deep. The knowledge of different patterns of existence will be required for angiographic procedures. Further the triangle is a potential epicardial access route to left fibrous ring. Thus detailed knowledge of variations will help cardiologist to achieve better outcome in interventional procedures with minimal complications.

• Anatomy and Cell Biology
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• v.56 no.3
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• pp.350-359
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• 2023

The suboccipital triangle (ST) is a clinically relevant landmark in the posterior aspect of the neck and is used to locate and mobilize the horizontal segment of the third part of the vertebral artery before it enters the cranium. Unfortunately, this space is not always a viable option for vertebral artery exposition, and consequently a novel triangle, the inferior suboccipital triangle (IST) has been defined. This alternative triangle will allow surgeons to locate the artery more proximally, where its course is more predictable. The purpose of this study was to better define the anatomy of both triangles by measuring their borders and calculating their areas. Ethical clearance was obtained from the University of Pretoria (reference number: 222/2021) and both triangles were subsequently dissected out on both the left and right sides of 33 formalin-fixed human adult cadavers. The borders of each triangle were measured using a digital calliper and the areas were calculated using Herons Formula. The average area of the ST is 969.82±153.15 mm², while the average area of the IST is 307.48±41.31 mm². No statistically significant differences in the findings were observed between the sides of the body, ancestry, or sex of the cadavers. Measurement and analysis of these triangles provided important anatomical information and speak to their clinical relevance as surgical landmarks with which to locate the vertebral artery. Of particular importance here is the IST, which allows for mobilisation of this artery more proximally, should the ST be occluded.

• Korean Journal of Computational Design and Engineering
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• v.17 no.4
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• pp.262-273
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• 2012

We present a novel GPU algorithm to compute outer cell boundaries of 3D arrangement subdivided by a given set of triangles. An outer cell boundary is defined as a 2-manifold surface consisting of subdivided polygons facing outward. Many geometric problems, such as Minkowski sum, sweep volume, lower/upper envelop, Bool operations, can be reduced to finding outer cell boundaries with specific properties. Computing outer cell boundaries, however, is a very time-consuming job and also is susceptible to numerical errors. To address these problems, we develop an algorithm based on GPU with a robust scheme combining interval arithmetic and multi-level precisions. The proposed algorithm is tested on Minkowski sum of several polygonal models, and shows 5-20 times speedup over an existing algorithm running on CPU.

• Proceedings of the Ginseng society Conference
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• 1984.09a
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• pp.75-82
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• 1984

고려인삼은 아시아 지역에서 수세기동안 강장제 및 치료약으로 광범위하게 사용되어 왔으며, 안전성 및 치료약으로서의 가치는 고대 한의서에 잘 명기되어있다. 그러나 근래에 들어서 인삼의 복용이 전세계로 확산됨에 따라 안전성 및 인삼의 약리작용에 대한 정확한 기전이 흥미를 끌게 되었다. 따라서 저자는 Salmonella typhimurium tester strain TA 100과 TA 98 및 V-79 Chinese hamster cell line을 이용하여 고려인삼의 안전성을 확인하기 위하여 본 연구를 수행하였다. 지금가지의 결과는 고려인삼이 안전하다는 것을 시사한다.

• Korean Journal of Head & Neck Oncology
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• v.12 no.2
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• pp.161-168
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• 1996

The neuorogenic tumor is known to be originated from neural crest, and the involved cells are Schwann cell, ganglion cell, and paraganglion cell. The Schwannoma, neurofibroma, and malignant schwannoma arise from the schwann cell, ganglioneuroma is from ganglion cell, and carotid body tumor and glomus tumor are originated from paraganglion cell. Authors reviewed thirty-eight patients of the neurogenic tumors in the head and neck, excluding intracranial tumor and Von-Recklinghausen disease, surgically treated at the Department of Surgery, Pusan Paik Hospital from January 1981 to May 1996. Of the 38 cases, 28 cases were schwannoma, 6 cases neurofibroma, 2 cases malignant schwannoma, and 2 cases paraganglioma. These tumors occurred at any age, but the majority of patients occurred in the fourth decade of life. There was female preponderance (M : F=1 : 1. 53) in sex ratio. The lateral cervical region was the most common distribution. 12 cases arose from the anterior triangle of neck, and 12 cases from the posterior triangle of neck. The major nerve origin of tumor could be identified in 30 cases (80%). 11 cases were treated by simple excision, and partial excision was 3 cases. Excision with parotidectomy 1 case, enucleation 11 cases, enucleation with parotidectomy 7 cases, radical neck dissection 1 cases, upper neck dissection 2 cases, suprahyoid dissection 1 case, Caldwell­Luc operation 1 case. The postoperative complications were hoarseness (2 cases), facial palsy (1 case), Homer syndrome (1 case), and hypoesthesia of tongue (1 case).

• Proceedings of the Korean Society of Applied Pharmacology
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• 1996.11a
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• pp.55-64
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• 1996

mouse chromesome2에 있는 agouti locus는 정상적으로는 털색깔을 조절하는 gene이다. mouse agouti gene은 최근에 cloning 되었고 131 amino acid peptide와 consensus signal peptide를 encode한다고 보고되었다. 이 논문에서 interspecies-DNA hybridization approach를 이용하여 mouse agouti gene의 human homologue를 cloning 하였다. Sequence analysis 결과, 이는 mouse gene에 85% 유사하였고 consensus signal peptide sequence 를 포함하는 132 amino acid를 coding하였다. somatic-cell hybrid mapping pannel과 Fluorescence-in-situ hybridization에 의한 chromosomal mapping을 한 결과, agouti gene은 MODY (maturity onset diabetes of the young), myeloid leukemia locus 등이 위치한 human chromosome 20q 11.2에 mapping 되었다. 성인 tissue로부터 추출한 RNA를 이용한 발현연구에 의하면 human agouti gene은 adipose tissue와 teatis에 발현되었다.

• Journal of the Korea Computer Graphics Society
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• v.4 no.1
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• pp.55-66
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• 1998

This paper presents a simple method for relieving the ambiguity problems within the sub-voxel based surface-fitting approach for the surface construction. ECB algorithm is proposed to avoid the ambiguity problem which is the root of the holes within the resulting polygon based approximation. The basic idea of our disambiguation strategy is the use of a set of predefined modeling primitives (we call SMP) which guarantees the topological consistency of resulted surface polygons. 20 SMPs are derived from the extension of the concept of the elementary modeling primitives in the CB algorithm [3], and fit one to five faces of them to the iso-surface crossing a cell with no further processing. A look-up table which has a surface triangle list is pre-calculated using these 20 SMPs. All of surface triangles in the table are from the faces of SMPs and are stored in the form of edge list on which vertices of each surface triangle are located. The resulted polygon based approximation is unique at every threshold value and its validity is guaranteed without considering the complicated problems such as average of density and postprocessing. ECB algorithm could be free from the need for the time consuming post-processing, which eliminates holes by revisiting every boundary cell. Through three experiments of surface construction from volume data, its capability of hole avoidance is showed.

• Journal of Korea Multimedia Society
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• v.12 no.11
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• pp.1623-1628
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• 2009

This paper presents the development of certain highly efficient and accurate method for computing tangent curves for two-dimensional vector fields. Unlike convention methods, such as Runge-Kutta, for computing tangent curves which produce only approximations, the method developed herein produces exact values on the tangent curves based on piecewise linear variation over a triangle in 2D. This new method assumes that the vector field is piecewise linearly defined over a triangle in 2D. It is also required to decompose the rectangular cell into two triangular cells. The critical points can be easily found by solving a simple linear system for each triangle. This method is to find exit points by producing a sequence of points on the curve with the computation of each subsequent point based on the previous. Because points on the tangent curves are calculated by the explicit solution for each triangle, this new method provides correct topologies in visualizing 2D vector fields.