• 열처리공학회지
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• 제7권3호
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• pp.199-205
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• 1994

The fracture characteristics and tool life of ceramics and WC, CBN cutting tool when turning heat treated steel STD11($H_RC$ 60) were investigated experimentally to clarify the machinability and optimum tool materials in cutting of difficult-to-cut material with high hardness. Forthermore, the behaviors of the tool wear and failure were examined with regard to cutting force. The hardened steel wore the cutting tool edge rapidily and increased the cutting forces, especially radial force. The tool was worn by the abrasive action. Flank Weat of $Al_2O_3-TiC$ ceramic and WC tool become relatively large and CBN & $Al_2O_3$, ceramic tool had a long life among the tool materials tested. The tool fracture patterns were just like minor cutting wear, flank wear, crater wear, notch wear, chipping. Flank wear rate was accelerated by occurrence of chipping. During the proceeding of machining, it was possible to foresee the catastrophic fracture of tool by abrupt increase of radial force.

• 생명과학회지
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• 제9권5호
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• pp.504-509
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• 1999

The trend of organogenesis in Xenopus presumptive ectoderm was studied by combined dose of activin A and IGF-1(insulin-like growth factor-1). In reference study of Asashima and his colleagues, the inductive patterns of various organs were reported with activin, the potent mesoderm inducing factor. In present study, the inducing pattern was cleared with combined-dose of concentration 1-100 ng/ml activin A and IGF-1. In addition, the result from single treatment of activin A was compared with former study. As a result, eye was differentiated in 5-20% of explants at 10 and 50 ng/ml concentrative combination of activin A. Otic vesicle was appeared in the entire concentrative combination of IGF-1. Pronephric duct was induced 19-38% of explants at the concentration of activin A 100 ng/ml by adding IGF-1. The comparison of single treatment of activin A was showed some difference in dose-dependent inducing pattern.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2013년도 제44회 동계 정기학술대회 초록집
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• pp.97-97
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• 2013

The exterior structures of natural organisms have continuously evolved by controlling wettability, such as the Namib Desert beetle, whose back has hydrophilic/hydrophobic contrast for water harvesting by mist condensation in dry desert environments, and some plant leaves that have hierarchical micro/nanostructures to collect or repel liquid water. In this work, we have provided a method for wettability contrast on metals by both nano-flake or needle patterns and tuning of the surface energy. Metals including steel alloys and aluminum were provided with hierarchical micro/nanostructures of metaloxides induced by fluorination and a subsequent catalytic reaction of fluorine ions on metal surfaces in water with various ranges from room to boiling temperature of water. Then, a hydrophobic material was deposited on the structured surfaces, rendering superhydrophobicity. Plasma oxidization induces the formation of superhydrophilic surfaces on selective regions surrounded by superhydrophobic surfaces. We show that wettability contrast surfaces align liquid water within patterned hydrophilic regions during the condensation process. Furthermore, this method could have a greater potential to align other liquids or living cells.

• The Korean Journal of Pain
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• 제8권2호
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• pp.328-330
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• 1995

A fourty-year-old housewife was admitted to the Department of Ear, Nose, and Throat from the emergency room, because of severe vertigo associated with positional changes of the head. Hallpike maneuver produced typical patterns of bilateral nystagmus consistent with benign paroxysmal positional vertigo(BPPV), and further geotropic rotatory nystagmus with positional change of the head in each direction. Direction of nystagmus reversed when the patients was repositioned upright. Particle repositioning maneuver was administered to her left ear but failed to relieve the severe dizziness associated with the head turning to the right. She was then referred to the patient received 27 SGB treatments and the patients was almost completely healed. It is unusual for the BPPV to occur bilaterally therefore reference concerning the effectiveness of SGB for the treatment of BPPV was difficult to obtain. In conclusion we would like to report the successful treatment of BPPV with SGB.

• 대한치과교정학회지
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• 제24권2호
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• pp.319-329
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• 1994

This study was carried out to research the adaptation patterns of head posture after activator therapy in functional class III malocclusion patients. For this purpose, 29 functional class III malocclusion patients, from the ages of 8 to 13 years old, were used. 1, Increse in capacity of oral cavity capacity were found in all the samples, but craniocervical angulation were varied into incresed group and decreased group after activator therapy. 2. Head posture exhibited the compensatory adaptation in the relative growth increments of the vertical dimension, ALFH and PLFH. 1) A group with more PLFH and less sagittal angle showed relatively small growth increment in PLFH during the treatment period, thus craniocervical angulation was increased. 2) A group with less PLFH and more sagittal angle showed relatively great growth incrmenet in PLFH during the treatment period, thus craniocervical angulation was decreased.

• 약학회지
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• 제49권1호
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• pp.109-113
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• 2005

In the present study treatment of IBMX, a phosphodiesterase (PDE) inhibitor, alone induced osteoclast formation in co-cultures of mouse bone marrow cells and calvarial osteoblasts. However, treatment of IBMX in combination with prostaglandin $E_2\;(PGE_2)$ inhibited osteoclast formation in a dose-dependent manner. Among various isozyme-specific PDE inhibitors, a PDE4 specific inhibitor, rolipram, showed similar effects as IBMX on osteoclast formation. To address the involvement of cyclic adenosine monophosphate (cAMP) in osteoclast formation, cAMP concentration in calvarial osteoblasts was investigated. When calvarial osteoblasts were co-cultured with IBMX alone or in combination with $PGE_2$, the patterns of cAMP concentration in calvarial osteoblasts were differ each other suggesting that cAMP in calvarial osteoblasts subtly regulates osteoclast formation.

• 대한물리치료과학회지
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• 제9권4호
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• pp.155-168
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• 2002

The purpose of study to know hand function in order to prevent disability or handicap. The ability to perform precise refined movements of hand is an important human function. Improvement in object manipulation is common goal of therapist. The ability to manipulate an object in the hand is need for many functional tasks, including writing, handling coins, small objects and ADL skills. Therapists have commonly used hand grip and pinch strengths as baseline measures to evaluate hand function. The patterns of grasps are precision grasp, power grasp, hook grasp, spherical grasp, sylindrical grasp, disc grasp, pinch, three point pinch and tip pinch. And the motion of in-manipulation are finger to palm translation, palm to finger, shift, simple rotation and complex rotation. The hand function are include to evaluate of ROM, sensation, muscle strength of hand. It used to evaluate of decision of effect and suppose of disability and acceptance of vocation. Good evaluation is need to pretreatment and baseline of treatment and help to evaluate of effect on treatment.

• Nuclear Engineering and Technology
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• 제52권1호
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• pp.170-177
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• 2020

A mixer with a new concept design has been adapted into water treatment plants. It reportedly cuts down the energy consumption of the mixer by the new mixer, which moves vertically and creates internal flows toward its bottom. However, no experimental observations have been made on the internal flow caused by a vertical impeller. In this study, a radiotracer experiment, radioactive particle tracking (RPT) technique, and particle image velocimetry (PIV) were carried out to visualize the flow in the mixer, and compared to each other. The results show that the flow patterns from these techniques are very similar to each other, and the performance of the mixer was good enough to mix the inner materials.

• Molecules and Cells
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• 제26권4호
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• pp.344-349
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• 2008

5-Fluorouracil (5-FU), a pyrimidine antagonist, has a long history in cancer treatment. The targeted pyrimidine biosynthesis pathway includes dihydropyrimidine dehydrogenase (DPD), which converts 5-FU to an inactive metabolite, and thymidylate synthase (TS), which is a major target of 5-FU. Using Caenorhabditis elegans as a model system to study the functional and resistance mechanisms of anti-cancer drugs, we examined these two genes in order to determine the extent of molecular conservation between C. elegans and humans. Overexpression of the worm DPD and TS homologs (DPYD-1 and Y110A7A.4, respectively) suppressed germ cell death following 5-FU exposure. In addition, DPYD-1 depletion by RNAi resulted in 5-FU sensitivity, while treatment with Y110A7A.4 RNAi and 5-FU resulted in similar patterns of embryonic death. Thus, the pathway of 5-FU function appears to be highly conserved between C. elegans and humans at the molecular level.

• Bulletin of the Korean Chemical Society
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• 제21권12호
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• pp.1181-1186
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• 2000

The structural evolution during the thermal treatment of $70SiO_2-3OTiO_2(mole%)$ sol-gel derived powders and films was investigated by FT-IR, Raman and XPS, and XRD. From these results, the $TiO_2-rich$ regions involving $Ti^{4+}$ ions in octahedral coordination were confirmed to be amorphous at $600^{\circ}C$. However, Raman spectra along with XRD patterns indicated that at high temperature (above $700^{\circ}C)$, the amorphous $TiO_2was$ segregating to form anatase crystal. Also, the effect of experimental variables such as thermal treatment, heating rate and exposure to water vapor on structural changes, refractive index and thickness of the film coated on sodalime-silicate glass were investigated.