• BMB Reports
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• 제43권5호
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• pp.344-348
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• 2010

Messenger ribonucleoprotein particles (mRNPs) are used to transport mRNAs along neuronal dendrites to their site of translation. Staufen2 is an mRNA-binding protein expressed in the cell bodies and cellular processes of different brain cells. It is notably involved in the transport of dendritic mRNAs along microtubules. Its knockdown expression was shown to change spine morphology and impair synaptic functions. However, the identity of Staufen2-bound mRNAs in brain cells is still completely unknown. As a mean to identify these mRNAs, we immunoprecipitated Staufen2-containing mRNPs from embryonic rat brains and used a genome wide approach to identify Staufen2-associated mRNAs. The genome wide approach identified 1780 mRNAs in Staufen2-containing mRNPs that code for proteins involved in cellular processes such as post-translational protein modifications, RNA metabolism, intracellular transport and translation. These results represent an additional and important step in the characterization of Staufen2- mediated neuronal functions in rat brains.

• 한국해양공학회:학술대회논문집
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• 한국해양공학회 2002년도 춘계학술대회 논문집
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• pp.257-262
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• 2002

Numerical model introduced in this study combines wave refraction-diffraction, breaking, bottom friction, lateral mixing, and critical shear stress and three sub-models for simulating waves, currents, and bottom change were briefly discussed. Simulations of beach processes and harbor sedimentation were also described at the coast neighboring Bangpo Harbor, Anmyundo, Chungnam, where the area has suffered from accumulation of drifting sand in a small fishing harbor with a wide tidal range. We also made model test for the case of a narrow tidal range at Nakdong river's estuary area to understand the effect of water level variation on the littoral drift. Simulations are conducted in terms of incident wave direction and tidal level. Characteristics of wave transformation, nearshore current, sediment transport, and bottom change are shown and analyzed. We found from the simulation that the tidal level impact to the sediment transport is very important and we should apply the numerical model with different water level to analyze sediment transport mechanism correctly. Although the model study gave reasonable description of beach processes and harbor sedimentation mechanism, it is necessary to collect lots of field observation data, including waves, tides and bottom materials, etc. for better prediction.

• Environmental Sciences Bulletin of The Korean Environmental Sciences Society
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• 제4권2호
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• pp.111-116
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• 2000

Transboundary air pollution has recently become an area of increasing scientific interest and political concern as countries are receiving air pollutants from their neighbors. In order to gain a better understanding of the long-range transport processes of air pollutants and the source-receptor relationships among neighboring countries, an atmospheric transport model coupled with a RAMS(Regional Atmospheric Modeling System) model was applied to the East Asia region during the entire month of January 1993. The scalar transport option of the RAMS model was used to calculate special atmospheric constituents such as trace gases or aerosols. The sulfate production in clouds and rainwater and its removal processes by dry and wet deposition were considered. The sulfate budget from source regions to receptor regions was estimated by analysing the source-receptor relationships. When a specific receptor site revealed a sulfate value higher than the sulfate concentration based on its own source origin, this was taken to indicate long-range transport from another source region. The contribution ratio from various source region was calculated. The contribution ratio of dry and wet deposition was higher on the main continent of the East region. Furthermore, the high deposition amounts were identified on the west coast of Korea and the East China Sea.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2005년도 학술발표회(2)
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• pp.1189-1192
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• 2005

Due to their slow degradation properties, hydrophobic organic contaminants in estuarine sediment have been a concern for risks to human health and aquatic organisms. Studies of fate and transport of these contaminants in estuaries are further complicated by the fact that hydrodynamics and sediment transport processes in these regions are complex, involving processes with various temporal and spatial scales. In order to simulate and quantify long-term attenuation of Polycyclic Aromatic Hydrocarbons (PAH) in the Elizabeth River, VA, we develop a modeling approach, which employs the U.S. Environmental Protection Agency's water quality model, WASP, and encompasses key physical and chemical processes that govern long-term fate and transport of PAHs in the river. In this box-model configuration, freshwater inflows mix with ocean saline water and tidally averaged dispersion coefficients are obtained by calibration using measured salinity data. Sediment core field data is used to estimate the net deposition/erosion rate, treating only either the gross resuspension or deposition rate as the calibration parameter. Once calibrated, the model simulates fate and transport PAHs following the loading input to the river in 1967, nearly 4 decades ago. Sediment PAH concentrations are simulated over 1967-2022 and model results for Year 2002 are compared with field data measured at various locations of the river during that year. Sediment concentrations for Year 2012 and 2022 are also projected for various remedial actions. Since all the model parameters are based on empirical field data, model predictions should reflect responses based on the assumptions that have been governing the fate and sediment transport for the past decades.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2005년도 춘계 학술대회
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• pp.255-263
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• 2005

Migration experiments of THO and 237Np have performed through a sampled granite core in Chemlab2 probe at the Aspo hard Rock laboratory. The elution curves of THO were analysed to determine hydraulic properties such as the extent of dispersion effect according to flow rates. The retardation phenomena of the solutes were observed and described with elution curves and migration plumes. After migration test, the rock core was opened, and the remaining radioactivities on the rock fracture surfaces were measured. The transport process was simulated with a two-dimensional channel model. The mass transport process was described with three types of basic processes ; advection, sorption and matrix diffusion. By the combination of these processes, effects of each process on transport were described in terms of elution curves and migration plumes. By comparing the simulation results to the experimental one, it was possible to analyse the retardation effect quantitatively.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 1993년도 수공학연구발표회논문집
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• pp.175-182
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• 1993

The complex nature of low flow transport and tranformation of nonconservative pollutants in natural streams with pools and riffles has been investigated using a numerical solution of a proposed mathematical model that is based on a set of mass balance equations describing hydrodynamic processes (advection, dispersion, and mass exchange mechanicms in streams and in storage zones) and chemical processes (reaction or decay). In this study, a mathematical model (named "Storage-Transformation Model") has been developed to predict adequately the non-Fickian nature of mixing and transformation mechanisms for decaying substances in natural streams under low flow conditions. Comparisons between the concentration-time curves predicted usingthe proposed model and the measured stream data shows that the Storage-Transformation Model yields better agreements in the goneral shape, peak concentration and time to peak than the 1-D dispersion model. The result of this study also demonstrates the differences between transport in pool-and-riffle streams versus transport in more uniform channels. The proposed model shows significant improvement over the conventional 1-D disperision model in predicting natural mixing and stroage processes in streams through pools and riffles.

• International Journal of CAD/CAM
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• 제6권1호
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• pp.19-27
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• 2006

To survive in the current shipbuilding industry it is of vital importance for shipyards to achieve an optimal utilization of resources, make an achievable planning and ensure that this planning is kept. Possible problems should be eliminated before production starts and if unexpected disturbances occur in the actual production the right measures should be taken. Due to the dynamic nature of the production process, the continuous variation in products and the complexity of both, all this can hardly be achieved with conventional static planning and analysis systems. Simulation provides a solution here, since this enables the modelling and evaluation of the dynamic relations between product and production process. After a global introduction to production simulation in general and the application of simulation at the Flensburger shipyard, this paper presents a tool that has been developed to simulate the various complex assembly processes taking place at shipyards. Subsequently the simulation model for the subassembly production at Flensburger, in which this tool is applied, will be discussed.

• Macromolecular Research
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• 제12권2호
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• pp.145-155
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• 2004

Facilitated transport membranes for the separation of olefin/paraffin mixtures have long been of interest in separation membrane science because olefins, such as propylene and ethylene, which are important chemicals in petrochemical industries, are currently separated by energy-intensive cryogenic distillation processes. Recently, solid polymer electrolyte membranes containing silver ions have demonstrated remarkable performance in the separation of olefin/paraffin mixtures in the solid state and, thus, they can be considered as alternatives to cryogenic distillation. Here, we review recent progress, and critical issues affecting in the use of facilitated olefin transport membranes; in particular, we provide a general overview with reference to carrier properties, transport mechanisms, and separation performance.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2008년도 춘계학술대회 논문집 센서 박막재료연구회 및 광주 전남지부
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• pp.91-97
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• 2008

Polymers submitted to thermo/electrical stress suffer from ageing that can drastically affect their functional behaviour. Understanding the physico/chemical processes at play during ageing and defining transport regimes in which these mechanisms start to be critical is therefore a prime goal to prevent degradation and to develop new formulation or new materials with improved properties. It is thought that a way to define these critical regimes is to investigate under which conditions (in terms of stress parameters) light is generated in the material by electroluminescence (EL). This can happen through impact excitation/ionization involving hot carriers or upon bi-polar charge recombination (a definition that excludes light from partial discharges, which would sign an advanced stage in the degradation process). After a brief review of the EL phenomenology under DC, we introduce a numerical model of charge transport postulating a recombination controlled electroluminescence. The model output is critically evaluated with special emphasize on the comparison between simulated and experimental light emission. Finally, we comment some open questions and perspectives.

• 한국지하수토양환경학회:학술대회논문집
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• 한국지하수토양환경학회 2005년도 총회 및 춘계학술발표회
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• pp.114-116
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• 2005

Natural attenuation has been actively studied and often selected as final clean-up process in remediation of contaminated ground-water and soil for the last decade. Accordingly, understanding of natural processes affecting the fate and transport of contaminants in the subsurface becomes important for a success of implementation of the natural remediation strategy, Contaminant advection and diffusion processes in the unsaturated zone are naturally related to environmental changes in the atmosphere. The atmospheric pressure changes affecting the transport of contaminants in the subsurface are investigated in this study. Moisture content, trichloroethylene (TCE) concentration, temperature, and pressure variations in the subsurface were measured for the July, August, November, and December 2001 at Picatinny Arsenal, New Jersey. These data were used for a one-phase flow and one-component transport model in simulating the soil-gas flow and accordingly the TCE transport in the subsurface in accordance with the atmosphere pressure variations at the surface. The soil-gas velocities during the sampling periods varied with a magnitude of $10^{-6}\;to\;10^{-7}\;m\;s^{-1}$ at land surface. The TCE advection fluxes at land surface were several orders of magnitude smaller than the TCE diffusion fluxes. A sensitivy analysis indicated that advection fluxes were more sensitive to changes in geo-environmental conditions compared to diffusion fluxes. Of all the parameters investigated in this study, moisture content has the most significant effect on TCE advection and diffusion fluxes.