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New Insights on the Biological and Emotional Pathogenesis of Eating Disorders (섭식장애의 생물학적 및 정서적 병인기전에 대한 새로운 지견)

  • Kim, Youl-Ri
    • Korean Journal of Biological Psychiatry
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    • v.20 no.3
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    • pp.74-79
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    • 2013
  • Objectives This paper aims to understand the emotional-biological pathogenesis of eating disorders, and translate the understanding into new brain directed treatments. Methods The first part of the review sets the eating behavior into the context of what is now understood about the central control of appetite and molecular biology. The second part of the review sees how emotion relates to the brain circuit involving eating disorders. Results In general, patients with anorexia nervosa restricting type were less sensitive to reward, whereas patients with bulimia nervosa and anorexia nervosa binge purging type were more sensitive to it. The emotional life of people with eating disorders centers on food, weight, and shape. The abnormalities in social and emotional functioning both precede and persist outside of eating disorders. Conclusions Research into understanding the biological framework of the brain in eating disorders suggests that abnormalities may exist in emotional and information processing. This aspect can be translated into novel brain-directed treatments, particularly in anorexia nervosa.

Dual function of MG53 in membrane repair and insulin signaling

  • Tan, Tao;Ko, Young-Gyu;Ma, Jianjie
    • BMB Reports
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    • v.49 no.8
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    • pp.414-423
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    • 2016
  • MG53 is a member of the TRIM-family protein that acts as a key component of the cell membrane repair machinery. MG53 is also an E3-ligase that ubiquinates insulin receptor substrate-1 and controls insulin signaling in skeletal muscle cells. Since its discovery in 2009, research efforts have been devoted to translate this basic discovery into clinical applications in human degenerative and metabolic diseases. This review article highlights the dual function of MG53 in cell membrane repair and insulin signaling, the mechanism that underlies the control of MG53 function, and the therapeutic value of targeting MG53 function in regenerative medicine.

A Study on Real Time Measurement of Frictional Coefficients by using Multi-components Load Cell (다축 힘센서를 이용한 마찰계수 실시간 측정방법 연구)

  • 권현준;권영하;박경희;오택열;백영남
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2003.06a
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    • pp.481-485
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    • 2003
  • This study describes the real-time measurement system which consist of multi-components load cell and linear motor. Operationg and data acquisition is controlled by PC. Multi-components load cell measures simultaneously the vertical force Fz and frictional force Fx when contactors move on sample surface. Linear motor is used to translate with constant speed without vibration. The frictional coefficient is calculated by Matlab$^{TM}$. The frictional coefficients between Al. plates. and fingertip and fabrics are measured.d.

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An Application of QFD to the Development of Full Automatic Temperature Controller (QFD를 적용한 전자동 온도조절장치 개발사례 연구)

  • 이기룡;박병춘
    • Journal of Korean Society for Quality Management
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    • v.30 no.1
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    • pp.61-73
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    • 2002
  • The Quality Function Deployment(QFD) is a Quality Management technique to maximize customers' satisfaction by reflecting customer requirements into all business processes, including concept definition, product planning, parts planning, process planning, production planning, and sales planning. The basic concept of the QFD is to translate customers' requirements appropriately into engineering characteristics, into parts characteristics, into process characteristics, and into specific requirements and activities in production. In this study, we reviewed and analyzed the application process of the QFD to the development of A2 FATC (Full Automatic Temperature Controller), an automotive component developed and produced by company A. It has been reported that by applying the QFD to the development of A2 FATC, company A. achieved 34% improvement in control robustness quality characteristic, 27% improvement in deviation quality characteristic, and 30% improvement in overall quality characteristics.

The Framework to Support a Common Way for Context-aware Applications

  • Baek, Jong-Kwun;Jung, Hae-Sun;Jeong, Chang-Sung
    • Journal of IKEEE
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    • v.11 no.4
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    • pp.279-282
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    • 2007
  • In this paper, we introduce the general way for producing context information to support context-aware applications. It can fetch raw data from the service environments, translate it to reasonable context information, and provide to multiple applications. It is designed originally for the ubiquitous computing middleware and based on the ontology processing model. Automated service applications can use this system as the form of libraries or of web services for deciding its semantic cause of action.

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Modeling the human memory in nerve fields

  • Fujita, Osamu;Kakazu, Yukinori
    • 제어로봇시스템학회:학술대회논문집
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    • 1992.10b
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    • pp.70-73
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    • 1992
  • This paper describes the modeling of human memory using a nerve field model which is proposed for modeling the mechanism of brain mathematically. In our model, two phases of memory, retention and recollection, are focused on. The former consists of two stages, short-term memory (STM) and long-term memory (LTM). The proposed model consists of three parts, the STM Layer, LTM Layer and the Intermediate Layer between them. Each of these is constructed by a nerve field. In the STM Layer, memorized information is retained dynamically in the form of the reverberating states of units within the layer, while in the LTM Layer, it is stored statically in the form of structures of the weight on the links between units. the Intermediate Layer is introduced to translate this dynamic representation in the STM Layer to the LTNI Layer, and also to extract the static information from the STM Layer. In addition to this, we consider the recollection of information stored in the LTM. Finally, the behavior of this model is demonstrated by computer simulation.

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A study on the implementation of an ASN.1 toll set for various macro processing (다양한 마크로 처리를 위한 ASN.1 도구 세트의 구현에 관한연구)

  • 김홍렬;임제탁
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.33A no.6
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    • pp.1-10
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    • 1996
  • Protocol specifications and service definitions for distributed open system applications are defined using ASN.1. Therefore, to implement an open system application likes MHS, it is necessary to have well defined encoding/decoding modules which translate ASN.1 protocol specifications into their transfer syntaxes. However, that work is usually tedius, time consuming, and error prone. In this paper, we designed and implemented a new ASN.1 tool set which includes a new ASN.1 run-time library, called HY BER/DER, and an enhanced ASN.1-to-C compiler, called HYASNC$^{+}$. HYASNC$^{+}$ automatically generates C language encoder/decoder stub files and heder files for basic ASN.1 types and subtypes defiend in X.208 recommandation, and all X400 MHS system macro definitions. And, we evaluated the performance of HYASNC$^{+}$ compiler and HY BER/DER run-tiem library, and tested the interoperability of ASN.1 run-time library.

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Simple Synthetic Manipulation Allowing for Morphological Diversity of Porphyrin-Based Microcrystals

  • Lee, Jun-Ho;Ryu, Eui-Hyun;Kim, Sung-Tae;Lee, Suk-Joong
    • Bulletin of the Korean Chemical Society
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    • v.32 no.2
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    • pp.609-612
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    • 2011
  • Amphiphilic (porphyrin)Sn$(OH)_2$ molecular building block can directly translate into well-defined solid-state microcrystalline structures. The crystalline diamond plates are obtained from ethanol and crystalline square plates are grown from methanol solution. With a simple synthetic manipulation during the microcrystal growth, the morphologies can be controlled by adopting different molecular packing. Consequently, morphologies of microcrystals have been diversified. Furthermore, the macroscopic crystals were obtained in the presence of cetyltrimethylammonium bromide (CTAB).

Deductions of KPIs for BSC and Process KPIs for BPM in Railway Construction (철도건설에서 BSC의 KPI도출과 BPM을 위한 프로세스 KPI도출)

  • Ryu Si-Wook;Ahn Byung-Jun;Ryu Myung-Wook
    • Journal of the Korean Society for Railway
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    • v.9 no.4 s.35
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    • pp.388-393
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    • 2006
  • Recently, Korean government demands that public sectors like railway construction should improve their management efficiency. It is necessary for railway construction supported by government budget to aim at the companywide management efficiency. The Balanced Scorecard (BSC) is known as integrated performance management framework that helps a company to translate strategic objective info relevant performance within an organization. This paper focuses on relationship between KPIs (Key Performance Indicators) used to measure the performance of railway construction industry and process KPT for BPM (Business Process Management). Also, the vision and strategies of the railway construction is introduced, and the CSFs (Critical Success Factors) and the KPI based on BSC is developed. Finally, this paper explores that there is a possibility to fulfill the strategic objectives of railway construction industry through the connectivity between KPI based on BSC and process KPI based on BPM. We explain the detailed procedures with an example of railway construction industry.

ACTUATION CHARACTERISTICS OF A MICROMIRROR FOR FINE-TRACKING (미세 트랙킹을 위한 마이크로미러 액튜에이터의 구동 특성)

  • Yee, Young-Joo;Bu, Jong-Uk;Kim, Soo-Kyung
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2000.06a
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    • pp.1521-1527
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    • 2000
  • A micromirror actuated by piezoelectric unimorph cantilevers is proposed as a tine-tracking device for high-density optical data storage. Bending motions of the metal/PZT/metal unimorphs translate an integrated micromirror along the out-of-plane vertical direction. The micromirror alters the optical path of the incident laser beam and linearly steers the reflected laser beam by its out-of-plane parallel actuation. Numerical analysis shows that the actuated micromirror can satisfy the tracking speed imposed by the requirement on the access time for the high-density optical data storage up to few tens Gbitlin2 owing to the light mass of the micromirror. In this paper, preliminary characteristics of the micro-machined PZT actuated micromirror (PAM) are reported. Only a 360 nm-thick PZT film deposited by sol-gel process shows both good electrical and mechanical characteristics for the fine-tracking actuator. The micromirror can be easily actuated up to several micrometers under low voltage operation condition well below 10 volts.

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