• Title/Summary/Keyword: transitional zone

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Feasibility of Novel Three-Dimensional Magnetic Resonance Fingerprinting of the Prostate Gland: Phantom and Clinical Studies

  • Dongyeob Han;Moon Hyung Choi;Young Joon Lee;Dong-Hyun Kim
    • Korean Journal of Radiology
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    • v.22 no.8
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    • pp.1332-1340
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    • 2021
  • Objective: To evaluate the feasibility of a new three-dimensional (3D) MR fingerprinting (MRF) technique for the prostate gland by conducting phantom and clinical studies. Materials and Methods: The new 3D MRF technique used in this study enables quick data acquisition and has a high resolution. For the phantom study, the MRF T1 and T2 values in an in-house phantom were compared with those of goldstandard mapping methods using linear regression analysis. For the clinical study, we evaluated 90 patients who underwent prostate imaging with MRF for suspected prostate cancer between September 2019 and February 2020. The mean T1 and T2 values were compared in the peripheral zone, transition zone, and focal lesions using paired t tests. The differences in the T1 and T2 values according to cancer aggressiveness were evaluated using one-way analysis of variance. Results: In the phantom study, the MRF T1 and T2 values showed a perfect correlation with the gold-standard T1 and T2 values (R > 0.99). In the clinical study, the T1 and T2 values in the peripheral zone were significantly higher than those in the transitional zone (p < 0.001, both). The T1 and T2 values in prostate cancer were significantly lower than those in the peripheral and transitional zones. The higher the grade of cancer, the lower the T2 values. Conclusion: The T1 and T2 values obtained from the 3D MRF showed a perfect correlation with the gold standard values in the phantom study. Differences in the T1 and T2 values among the different zones of the prostate gland were identified using 3D MRF in patients.

지지부 위치와 벽면 두께변화에 따른 구형 인공위성 추진제 탱크의 강도해석

  • 한근조;전언찬;김중완;안성찬;심재준
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 1997.04a
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    • pp.528-532
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    • 1997
  • The structure of satellite was of six parts of control system, power system, thermal control system, remote measurement command system, propellant system and thrust system. In these parts, propellant system consists of propellant tank and thrust device. What we want to perform is optimum design to minimaize the weight of propellant tank. In order to design optimal propellant tank, several parameters should be adopted form the tank geometry like the relative location of the lug and variation of the wall thickness. So the analysis was executed by finite element analysis for finding optimal design parameters. The structure was devided into 3 parts, the initial thickness zone, the transitional zone, and the weak zone,whose effects on the pressure vessel strength was investigated. Finally the optimal lug location and the three zone thickness were obtained and the weight was compared with the uniform thickness vessel.

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A case of transitional carcinoma in the nasal cavity of a dog (개의 비강 내 이행암종 증례)

  • Kang, Hwa-Jung;Kang, Sang-Chul;Jung, Ji-Youl;Jo, Suk-Hee;Roh, In-Soon;Lee, Joo-Myung;Cheong, Jongtae;Kim, Jung-Hun;An, Min-Chan;Bae, Jong-Hee;Kim, Jae-Hoon
    • Korean Journal of Veterinary Research
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    • v.48 no.3
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    • pp.305-310
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    • 2008
  • A 10-year-old female Yorkshire terrier with the clinical signs of nasal swelling, epistaxis and nasal discharge was presented to the Veterinary Teaching Hospital in the Cheju National University. Abnormal nasal mass was detected in physical examination and radiographic findings. After surgical excision, the sample of nasal mass was referred to Pathology Department of Veterinary Medicine. Grossly, the mass was soft, friable, and $2.5{\times}4cm$ cm in size. Histopathologically, the mass was composed of mediumsized non-keratinizing columnar to polyhedral cells arranged in anastomosing ribbon and large nest. It has complex in-folding of thick epithelial layers separated by fibrovascular septa. Tumor cells showed characteristic palisading arrangement of columnar cells, and perpendicularly distributed to the basement membrane. The cells had pale basophilic cytoplasm, oval nucleus and one or more nucleoli, and indistinct cellular border. Many tumor cell emboli were presented in lymphatics. Immunohistochemistry revealed that tumor cells were cytokeratin (CK) 19 and CK clone MNF116 positive and but CK7 and CK high molecular weight negative. Based on the gross, histopathologic, and immunohistochemical findings, the mass was diagnosed as transitional carcinoma in nasal cavity. In our best knowledge, this is the first report of transitional carcinoma originated from transitional zone of canine nasal cavity in Korea.

Radioaerosol Scan Manifestations of Diffuse Panbronchiolitis (미만성 세기관지염의 연무흡입 폐환기스캔 소견)

  • Kim, Hak-Hee;Choi, Byung-Gil;Bahk, Yong-Whee;Chung, Soo-Kyo;Park, Seog-Hee;Shin, Kyung-Sub;Park, Sung-Hak
    • The Korean Journal of Nuclear Medicine
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    • v.28 no.2
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    • pp.192-199
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    • 1994
  • Diffuse pahbronchiolitis(DPB) is a relatively new, chronic, nonspecific, inflammatory disease of the lung that typically involves the airways in the "transitional" zone of the lung. Clinically, DPB strongly resembles chronic obstructive pulmonary disease (COPD) and the distinction between the two is crucial because the former is often fatal, requiring different therapeutic strategies. This study was prospectively carried out to assess diagnostic usefulness of radioaerosol scan(RAS) in DPB. RAS findings were analyzed with respect to the location and extent of abnormal aerosol deposition in the lung divided into the central, intermediary, and transitional airways and the peripheral airspaces. RAS showed mottled aerosol deposits characteristically in the transitional and intermediary airways with peripheral airspace defects. Such a deposition pattern contrasted sharply with central aerosol deposition of COPD. In conclusion, RAS appears to be a convenient, noninvasive, and useful diagnostic method of DPB.

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A Study on the Supportive Stiffness in Transitional Zones through Moving Load-Based Three-Dimensional Modeling (이동하중과 3차원 모델링을 통한 접속부 지지강성연구)

  • Woo, Hyeun-Joon;Lee, Seung-Ju;Kang, Yun-Suk;Cho, Kook-Hwan
    • Proceedings of the KSR Conference
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    • 2011.10a
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    • pp.1542-1549
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    • 2011
  • The Transitional zone between bridge abutment and earthwork is one of the representative vulnerable zones in railway where differential settlements may take place due to the different supportive stiffness. Although transitional zones are managed with stricter standards than those of the other earthwork zones either in the design and construction stages, it is very difficult to prevent differential settlement perfectly. A three-dimensional numerical analyses were performed by applying train moving load in this study. The analytical model including abutments and earthwork zones was constituted with rail, sleepers, track concrete layer (TCL), hydraulic stabilized base (HSB), reinforced road bed, and road bed using railway and road base structure. The clamp connecting the rail and sleeper were also modeled as the element with spring coefficient. The train wheel is modeled in the actual size and moved on the rail with 300 km/hr speed. The deformation characteristics at each point of the rail and the ground were considered in detail when moving the train wheel. The analysis results were compared with those from the two-dimensional analysis without considering moving load. The research results show that displacement and stress were greater in the three-dimensional analysis than in other analyses, and the three-dimensional analysis with moving load should be performed to evaluate railway performance.

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Numerical simulation of unsteady flow field behind bluff body (Bluffbody 비정상 유동장에 대한 수치해석)

  • Ryu, Myeong-Seok;Gang, Seong-Mo;Kim, Yong-Mo
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.21 no.3
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    • pp.350-357
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    • 1997
  • The transient incompressible flow behind the axisymmetric bluff body is numerically simulated using the random vortex method(RVM). Based on the vorticity formulation of the unsteady Navier-Stokes equations, the Lagrangian approach with a stochastic simulation of diffusion using random walk technique is employed to account for the transport processes of the vortex elements. The numerical solutions for 2-dimensional recirculating flow behind a backward-facing step in the laminar range of Reynolds number are compared with experimental data. The present simulation focuses on the transitional flow regime where the recirculation zone behind the bluff body becomes highly unsteady and large-scale vortex eddies are shed from the bluff body wake due to intrinsic shear layer instabilities. The unsteady vertical flow structures and the mixing characteristics behind the bluff body are discussed in detail.

VALIDATION OF GRID AND BOUNDARY CONDITIONS FOR OPTIMAL DESIGN OF HEAT RECOVERY SYSTEM (열 회수 시스템의 최적 설계를 위한 격자 및 경계 조건 검증에 관한 연구)

  • Lee, D.G.;Shin, S.W.
    • 한국전산유체공학회:학술대회논문집
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    • 2011.05a
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    • pp.608-609
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    • 2011
  • In this study, we tried to validate FLUENT solver model and domain setting for the problem of convective heat transfer in multiple tube bank under transitional zone. We have paid special attention to verify proper boundary conditions and the grid convergence. Through validation work, it is found that unsteady solution method with two-dimensional simulation domain can produce reasonable accurate results compared with existing experimental data. Simulation results with steady solution generates relatively large error. We found that both steady and unsteady method for three-dimensional domain shows acceptable accuracy. Further parametric study for deriving correlation from transverse and longitudinal pitch is currently underway.

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Anhui Water Resource Situation and General Plan

  • Yiqun, Hou
    • Proceedings of the Korea Water Resources Association Conference
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    • 2007.05a
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    • pp.67-73
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    • 2007
  • Anhui Province, with a total north-south length of 570km and an east-west width of 450km and a total area of 139.6 thousand km2, accounts for 1.45% of China's total area. The landform and land feature of Anhui Province is diverse, and generally it can be divided into 5 natural regions: (1) Huaibei Plain; (2) Jianghuai Hillocks; (3) Dabie Mountains in the West of Anhui Province; (4) Yanjiang Plain, (5) Mountain Area of southern Anhui Province. Anhui Province is located in the transitional zone of warm and humid zone and subtropical zone, and its mean annual precipitation is 800-1800mm. The province, which has diverse climate, multiple land forms and many rivers and lakes, passes three basins (Huaihe River, Yangtze River and Xin'an River) and has large differences in the time distribution and regional distribution of water resource. Therefore, the development and usage conditions of the water resource in different regions are different.

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Evaluation of Behaviors in Abutment Transition Zone Depending on Constrution Orders and Number of Piles (뒤채움 시공순서 및 말뚝 수에 따른 교대 접속부 거동평가)

  • Kim, Ung-Jin;Jeong, Rag-Gyo;Kim, Dae-Sang
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.1
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    • pp.1-7
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    • 2017
  • The RAR (Reinforced Abutment for Railways) is an economical abutment to reduce the settlement of a transitional zone and horizontal displacement of an abutment by constructing backfill before the abutment. In this paper, the performance of the RAR depending on the pile installation was evaluated using 2D (Dimensional) finite element analysis and compared with the existing abutment (with 5 rows pile). Numerical analysis showed that increasing pile installation is more effective in reducing horizontal displacement and earth pressure than settlement of the transitional zone. The horizontal displacement and earth pressure of the RAR was approximately 26~37% and 59~83% compared to the existing abutment by changing the pile installation. More pile installation led to a greater reduction of the horizontal displacement and earth pressure of the RAR. In addition, the horizontal earth pressure of RAR is influenced considerably by the reinforcement, pile, foundation, and stiffness of the ground.

Overtopping Model Experiments and 3-D Seepage Characteristics of the Embankment of Deteriorated Homogeneous Reservoirs (노후화된 균일형 저수지 제체의 월류모형실험과 3차원 침투특성)

  • Lee, Young Hak;Lee, Tae Ho;Lee, Dal Won
    • Journal of The Korean Society of Agricultural Engineers
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    • v.61 no.2
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    • pp.13-23
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    • 2019
  • In this study, an overtopping model experiments and three dimensional seepage characteristics at the deteriorated homogeneous reservoirs were performed to investigate the behavior of failure for embankment and spillway transitional zone due to overtopping. The failure pattern, pore water pressure, earth pressure and settlement by overtopping were compared and analyzed. The pattern of the failure by overtopping was gradually enlarged towards reservoirs crest from the spillway transition zone at initial stage. In the rapid stage and peak stage, the width and depth of failure gradually increased, and the pattern of the failure appeared irregular and several direction of the erosion. In the early stage, the pore water pressure at spillway transitional zone was more affected as its variation and failure width increased. In the peak stage, the pore water pressure was significantly increased in all locations due to the influence of seepage. The earth pressure increased gradually according to overtopping stage. The pore pressure by the numerical analysis was larger than the experimental value, and the analysis was more likely to increase steadily without any apparent variation. The horizontal and vertical displacements were the largest at the toe of slope and at the top of the dam crest, respectively. The results of this displacement distribution can be applied as a basis for determining the position of reinforcement at the downstream slope and the crest. The collapse in the overtopping stage began with erosion of the most vulnerable parts of the dam crest, and the embankment was completely collapsed as the overtopping stage increased.