• Speech Sciences
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• v.7 no.3
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• pp.197-218
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• 2000

The vocal tract shapes were measured from tracheoesophageal speakers during the sustained phonation of five Korean vowels /u/, /o/, /a/, /e/, /i/ using magnetic resonance image(MRI). The subject's original vowel utterances with speech intelligibility and the synthesized vowels from MR images were analyzed. The results were as follows: (1) The vowels /a/, /e/, /i/ were perceived as the same sounds of actual subject's speech, but the vowels /o/ and /u/ were perceived as /$\partial$/ and strained /u/, respectively. (2) The synthesized vowels /a/ and /e/ from the MR images were perceived as the same sounds, but the vowels /u/, /o/, /i/ were perceived as different sounds. (3) The synthesized vowel by the expanded pharyngeal segment of 3 times in vowel /o/ was perceived as more natural than that of 2 times. The pharyngeal areas with varied sizes should be experimented to secure better speech production because the correct shapes of the vocal tract lead to distinct vowel production.

• Archives of Plastic Surgery
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• v.49 no.5
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• pp.617-632
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• 2022

Tracheoesophageal puncture (TEP) and voice prosthesis insertion following laryngectomy may fail to form an adequate seal. When spontaneous closure of the fistula tract does not occur after conservative measures, surgical closure is required. The purpose of this study was to summarize the available evidence on surgical methods for TEP site closure. A comprehensive search across PubMed, Web of Science, SCOPUS, and Cochrane was performed to identify studies describing surgical techniques, outcomes, and complications for TEP closure. We evaluated the rate of unsuccessful TEP closure after surgical management. A meta-analysis with a random-effect method was performed. Thirty-four studies reporting on 144 patients satisfied inclusion criteria. The overall incidence of an unsuccessful TEP surgical closure was 6% (95% confidence interval [CI] 1-13%). Subgroup analysis showed an unsuccessful TEP closure rate for silicone button of 8% (95% CI < 1-43%), 7% (95% CI < 1-34%) for dermal graft interposition, < 1% (95% CI < 1-37%) for radial forearm free flap, < 1% (95% CI < 1-52%) for ligation of the fistula, 17% (95% CI < 1-64%) for interposition of a deltopectoral flap, 9% (95% CI < 1-28%) for primary closure, and 2% (95% CI < 1-20%) for interposition of a sternocleidomastoid muscle flap. Critical assessment of the reconstructive modality should take into consideration previous history of surgery or radiotherapy. Nonirradiated fields and small defects may benefit from fistula excision and tracheal and esophageal multilayer closure. In cases of previous radiotherapy, local flaps or free tissue transfer yield high successful TEP closure rates. Depending on the defect size, sternocleidomastoid muscle flap or fasciocutaneous free flaps are optimal alternatives.

• Clinical and Experimental Pediatrics
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• v.53 no.6
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• pp.705-710
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• 2010

Purpose: To determine the clinical manifestations and outcomes of patients with tracheoesophageal fistula (TEF) and esophageal atresia (EA) born at a single neonatal intensive care unit. Methods: A retrospective analysis was conducted for 97 patients with confirmed TEF and EA who were admitted to the neonatal intensive care unit between 1990 and 2007. Results: The rate of prenatal diagnosis was 12%. The average gestational age and birth weight were $37^{+2}$ weeks and $2.5{\pm}0.7kg$, respectively. Thirty-one infants were born prematurely (32%). Type C was the most common. The mean gap between the proximal and distal esophagus was 2 cm. Esophago-esophagostomy was performed in 72 patients at a mean age of 4 days after birth; gastrostomy or duodenostomy were performed in 8 patients. Forty patients exhibited vertebral, anorectal, cardiac, tracheoesophageal, renal, limb (VACTERL) association with at least 2 combined anomalies, and cardiac anomaly was the most common. The most common post-operative complications were esophageal stricture followed by gastroesophageal reflux. Balloon dilatation was performed for 1.3 times in 26 patients at a mean age of 3 months. The mortality and morbidity rates were 24% and 67%, respectively, and the most common cause of death was sepsis. The weight of approximately 40% patients was below the 10th percentile at 2 years of age. Conclusion: Mortality and morbidity rates of patients with TEF and EA are high as compared to those of infants with other neonatal surgical diseases. Further efforts must be taken to reduce mortality and morbidity and improve growth retardation.

• Journal of Chest Surgery
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• v.43 no.6
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• pp.820-823
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• 2010

There are still some controversies in treatment strategy for the very low-birth-weight baby with esophageal atresia even though the result of primary repair has been improving. We report a successful end to end anastomosis with staged approach in one of twin weighing 1,270 g at birth.

• Advances in pediatric surgery
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• v.1 no.2
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• pp.162-169
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• 1995

Since 1988, we have performed esophageal replacement with the reversed gastric tube on four esophageal atresia patients. Three patients had long-gap esophageal atresias and one patient had recurrent tracheoesophageal fistula that was previously operated on three times. One combined imperforate anus. The youngest patient was 6-month-old and the oldest, 34-month-old at the time of procedure. The technique of gastric tube construction is described. There have been both major and minor complications. Although two patients had shown distal tube strictures as late complications. those were solved with tuboplasties on 29 months and 48 months, postoperatively. Growth and development have been acceptable in all four patients, although most remain in the lower percentiles for growth and height, a condition that usually predates the esophageal substitution. Conclusively, reversed gastric tube interposition has proved very satisfactory for long-gap esophageal atresia that cannot be anastomosed primarily even by spiral myotomy and esophageal atresia with recurrent tracheoesophageal fistula having destroyed esophagus due to previous operation.

• Korean Journal of Bronchoesophagology
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• v.9 no.1
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• pp.30-38
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• 2003

Cancers of the cervical esophagus occur uncommonly, but treatment is remaining a challenging problem and surgery demands special knowledge of abdominal, thoracic, and neck surgery. The primary risk factor is chronic heartburn, leading to a sequence of esophagitis, Barrett's esophagus, reflux esophagitis and etc. Among the various treatment modalities, Surgery is still a mainstay of treatment. The main aim of surgery is not only oncologically adequate resection but also preservation or restoration of physiologic functions, such as deglutition and phonation. Surgical treatment of cervical esophageal cancer is influenced by special problems arising from tumor factors, patient factors and surgeon factors. Complete clearance of loco-regional disease and prevention of postoperative complications are of particular importance for the improvement of long-term survival in patients with these cancers. So the cervical and thoracic extension of these tumors usually required an extensive lymphadenectomy with primary resection. Radical resection of the primary site almostly include sacrifice of the larynx, but the voice could be rehabilitated with various methods, such as tracheoesophageal prosthesis or tracheoesophageal shunts, etc. Restoration of the esophageal conduit can be performed using gastric or colon interposition, radial forearm free flap or jejunum free flap, etc. Recently, the advances of radiation therapy and chemotherapy will enable less extended resections with greater rates of laryngeal preservation. At initial presentation, up to 50％ to 70％ of patients will have advanced locoregional or distant disease with virtually no chance for cure. Patients with advanced but potentially resectable esophageal cancer are generally treated by surgery with some form of neoadjuvant chemotherapy, radiotherapy, or both, with 5-year survivals in the 20％ to 30％ range. So the significant adverse factors affecting survival should be taken into account to select the candidates for surgery.

• Phonetics and Speech Sciences
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• v.5 no.4
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• pp.25-32
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• 2013

This research is aimed at finding the acoustic characteristics of different voice rehabilitation techniques, the electrolaryx (EL), standard esophageal (SE), and tracheoesophageal (TE), used on 17 patients with laryngectomees. The analysis of the voice qualities was achieved using MDVP. In order to compare the acoustic characteristics, patients were asked to produce the vowel /a/ sound. The acoustic analysis included fundamental frequency (f0), jitter, shimmer, and noise-to-harmonic ratio (NHR). The main acoustic results showed no significant statistical differences between the average measurements of SE and TE speakers. It was found that the current study showed the same tendency found in previous studies. There was also a significant difference between SE and EL speakers. On the other hand, there were no significant statistical differences between the average measurements of TE and EL speakers on all acoustic measurements. This research will contribute to establishing a baseline related to speech characteristics in voice rehabilitation for patients with laryngectomees. In future, the present findings and issues should be considered in the context of gender. Specifically, the number of women who are diagnosed with laryngeal cancer continues to rise and their acoustic characteristics may indeed differ from those of men.

• Phonetics and Speech Sciences
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• v.5 no.4
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• pp.17-24
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• 2013

This study is aimed at finding out different types of speech characteristics categorized based on voice rehabilitation techniques used on twenty-six patients (all-male) with total or partial laryngectomees. The speech intelligibility of standard esophageal (SE), tracheoesophageal speech (TE), and electriclarynx (EL) was measured by using the CSL and eleven listeners were instructed to rate the speech on a 5-point scale. The vowel space parameters such as vowel space, VAI, FCR, and F2 ratio were measured by averaging 5 repeats of each vowel (/a/, /e/, /i/, /u/) and the results were put into the parameter formula. The results showed significant statistical differences in speech intelligibility and vowel space between SE and TE. The speech intelligibility and vowel space of TE were higher than those of SE or EL and there was a high correlation between speech intelligibility and some parameters (vowel space, VAI, F2 ratio). The results also showed that TE's speech characteristics were most similar to normal groups comparing with SE and EL, but still very deviant in laryngeal speech. This was due to insufficient airflow intake into the esophagus when producing sounds, and because articulation movement was carried out differently among groups. Therefore, these findings will contribute to establishing a baseline related to speech characteristics in voice rehabilitation for patients with alaryngeal speech.

• Journal of Chest Surgery
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• v.30 no.6
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• pp.636-640
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• 1997

The common cause of tracheoesophageal fistula(T-I fistula) after tracheal intubation is ulceration and necrosis of the posterior wall of trachea by compression pressure generated by cuff. We experienced a young woman sustaining a T-I fistula which was found on the 12th day of intubation for cardiopulmonary resuscitation. Because spontaneous closure of the fistula is far uncommon, operative closure should be aimed for and should be done as soon as diagnosis is conformed. We delayed ope ative closure because of poor general condition of the patient. In spite of delayed reconstruction, the tracheal reconstruction itself was successful, but the patient died of peritonitis induced sepsis on the postoperative 41th day.

• Advances in pediatric surgery
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• v.17 no.2
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• pp.154-161
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• 2011

Tracheoesophageal fistula without esophageal atresia (H-type TEF) is a congenital anomaly that is characterized by a fistula between the posterior wall of the trachea and the anterior wall of the esophagus, not accompanied by esophageal atresia. The purpose of this study is to investigate the clinical characteristics, diagnostic time, the side of cervical approach and short term result after surgery by searching medical records of patients treated for H-type TEF. The search was done at University of Ulsan, Department of Pediatric Surgery of Asan Medical Center, and the total number of patients from May 1989 to December 2010 was 9 with M:F ratio of 1:2. The median gestational age was $39^{+6}$ ($32^{+6}{\sim}41^{+0}$) wks. Seven out of nine patients were born at term and the other two were born premature. The clinical presentation was aspiration pneumonia, difficulty in feeding, chronic cough, vomiting, abdominal distension and growth retardation. The symptoms presented right after birth. The diagnosis was made with esophagography and the median time of diagnosis was 52 days of life. The majority of surgical corrections were performed within two weeks of diagnosis (median; 15d, range; 1d - 6m). Six patients had associated anomalies, and cardiac anomalies were most common. The cervical approach was utilized in all cases (right 2, left 7). Transient vocal cord palsy and minor esophageal leakage complicated two cases. Although the diagnosis of H-type TEF was difficult and often delayed, we had a good short term result. The left cervical approach was preferred.