• 제목/요약/키워드: toxic substance

검색결과 234건 처리시간 0.026초

탄화수소 누출로 인한 위험분석 평가 방법론 연구 (A Methodology for Assessing Risk from Released Hydrocarbon)

  • Keun-Won Lee
    • 한국안전학회지
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    • 제13권2호
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    • pp.170-180
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    • 1998
  • 본 연구는 밀폐된 지역에서 경험적 증발속도식을 사용하여 누출된 탄화수소의 농도 계산방법을 소개하였다. 그 접근방법은 가정된 조건하에서 공기중의 탄화수소 누출 농도를 추정하여 노출된 근로자나 사람의 개인적 위험평가를 위해 probit 표현식에 의한 위험평가 방법론을 제시하였다. 벤젠-공기 및 톨루엔-공기계에 대해 독성기준과 사람의 노출데이타가 조사되어졌고, 위험평가를 위한 가이드라인를 제시하였다. 탄화수소와 비독성 물질의 혼합물의 치사농도의 몰분율에 다른 probit 상수값들을 예측하였다. 몰분율에 따라 계산된 probit값은 밀폐된 작업구간에서 독성을 예방하기 위한 가이드라인을 추정하기 위해 사용될 수 있다.

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소현세자(昭顯世子)의 사인(死因)에 관한 고찰(考察) (The Research of the crown prince So-Hyeon's death cause)

  • 김훈
    • 대한한의학원전학회지
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    • 제19권3호
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    • pp.210-227
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    • 2006
  • Many historians presume that several kings included the crown prince were killed by poison in the Jo-Soon dynasty. Above all, there is every possibility of killing the crown prince So-Hyoon(昭顯) by poison. The crown prince So-Hyeon was detained for 8 years in Sim-Yang(瀋陽). He died suddenly in two month from coming home. According to an authentic record, official death causes were malaria. But there is little possibility that a young crown prince die of malaria at the age of 34. His dead body shows change of skin color and bleeding from the ear, eye, mouth, and nose. This is the sufficient evidence that he was killed by poison. King In-Jo have a doubt that he was ousted from his post by crown prince So-Hyeon in conspiracy with cheong imperial court. Especially, after the crown prince So-Hyeon's death, owing to cold attitude that king In-Jo shows and a tragic affair that occurred to the crown prince's family, king In-Jo is under suspicion as the mastermind of the murder. Another poisoners are Jo-So Yong(趙昭容) and Lee-Hyeong Ik(李聲益). Jo-So Yong, a royal harem, intrigue against the couple of crown prince So-Hyoon. Lee-Hyeong Ik that win king In-Jo's favor take charge of the medical treatment. We supposed that toxic substance is arsenic poison.

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자외선 조사에 의한 수용액 중에 함유되어 있는 엔도설판 alpha, beta, sulfate의 광분해 (Photodegradation of Endosulfan alpha, beta, and sulfate in Aqueous Solution by UV Irradiation Only)

  • 유건상;김미향;이화성;황현직
    • 한국환경과학회지
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    • 제15권11호
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    • pp.1061-1067
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    • 2006
  • Photodegradation of endosulfan alpha, beta, and sulfate known as the most toxic substance among organochlorine pesticides by UV irradiation was studied at experimental conditions such as different pH aqueous solution and reaction time. The initial concentration of endosulfan alpha, beta, and sulfate in aqueous solution was 500 ppb, respectively. The experiment of photodegradation was conducted in a quartz reactor equipped with a low pressure mercury lamp (100 W, 240 nm). The samples were withdrawn from the photo reactor at intervals of 0, 10 min, 30 min, 1 hr, 2 hr, and 4 hr. Endosulfan sulfate was never hydrolyzed and photodegraded in wide range of pH. At pH 5 and reaction time (240 min), endosulfan alpha was photodegraded up to 67%. Both endosulfan alpha and beta were started to photodegrade at pH 6.5 with the lapse of time, resulting in approximately 99.9% and 87.2% of photodegradation efficiency, respectively. Furthermore, at pH 9, endosulfan alpha and beta was partially hydrolyzed and photodegraded to 99.5% at 120 min of reaction time. During the photolysis, any photo-products of endosulfan alpha, beta, and sulfate were not observed.

건물 외벽 패널용 경량기포콘크리트(AAC)의 CaO/$SiO_2$ 혼합비에 따른 강도 특성 평가 (Strength Characteristics according to the mixed CaO/$SiO_2$ Ratio to Autoclaved Aerated Concrete(AAC) used on the Exterior Panel in Buildings)

  • 김영호
    • 한국디지털건축인테리어학회논문집
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    • 제11권3호
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    • pp.35-42
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    • 2011
  • The exterior system of buildings, which is the typical curtain wall, has been made with glass and metal. Theses materials, however, have weaknesses such as inadequate insulating quality, short durability, combustibility and toxic substance. On the other hand, Autoclaved Aerated Concrete(AAC) or Autoclaved Lightweight Concrete(ALC) possess the great energy efficiency and the superb insulating quality as substitute of existing exterior system materials. In this research, strength characteristics and bubble dispersion of hydrothermal synthesis process of AAC based on CaO/$SiO_2$(C/S) ratio are analyzed. C/S ratio is determinated and bubble distribution and compressive strength are studied through the test of varied water-to-solid mineral ratio(W/S). In hydrothermal synthesis program, final C/S ratio is determined as 0.7 consider of the manufacturing process and hydrothermal synthesis is done at $180^{\circ}C$ for 7 hours. The analysis shows slurry has about 2,300cP viscosity and 0.56 specific gravity therefore it is expected AAC has the appropriate facility in the manufacturing process and Hydrates of AAC's Expansion.

생석회와 실리카퓸을 활용한 경량기포콘크리트(ALC)의 강도특성 개선을 위한 실험적 연구 (An Experimental Study on the Strength Characteristic Improvement of the Autoclaved Lightweight Concrete(ALC) containing Quicklime and Silica Fume)

  • 김영호;송훈
    • 한국디지털건축인테리어학회논문집
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    • 제11권4호
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    • pp.21-27
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    • 2011
  • These materials in architecturally glass or metal have weaknesses such as inadequate insulating quality, combustibility and toxic gases in fires substance. However, Autoclaved Lightweight Concrete(ALC) has excellent thermal insulation properties and seem to possess the superb insulating quality as substitute of existing exterior materials. This research is to compare experimentally to the kind of the strength properties of ALC materials which mixed with blast furnace slag pounder and silica fume. For the purpose of increasing the strength, the plastic states of ALC evaluate the physical characteristics as microstructure and strength according to various specific gravity. According to the quicklime quantity the compressive strength is proportionate depend on the absolute dried specific gravity. When not putting in 10% quicklime, the compressive strength appeared most lowly with 14.0MPa. When putting in the quicklime, the strength appeared higher with 15.1MPa. And strength of specimen containing 2.25% silica fume is 15.6MPa increased 10.3% than reference specimen 14.0MPa.

Effect of Vitamin E Against the Cytotoxicity of Reactive Oxygen Species on Vascular Endothelial Cells

  • Kwon O-Yu;Park Seung-Taeck
    • 대한의생명과학회지
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    • 제12권3호
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    • pp.255-259
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    • 2006
  • Reactive oxygen species (ROS) is one of the main pathological factors in endothelial disorder. For example, an atherosclerosis is induced by the dysfunction of vascular endothelial cells. The dysfunction of vascular endothelial cells cascades to secrete intercellular adhesion molecule (ICAM)-l substance by ROS. Therefore, The ROS is regraded as an important factor of the injury of vascular endothelial cells and inducement of atherosclerosis. Oxygen radical scavengers playa key role to prevention of many diseases mediated by oxidative stress of ROS. In this study, the toxic effect of ROS on vascular endothelial cells and the effect of antioxidant, vitamin E on bovine pulmonary vascular endothelial cell line (BPVEC) treated with hydrogen peroxide were examined by the colorimetric assay. ROS decreased remarkably cell viability according to the dose- and time-dependent manners. In protective effect of vitamin E on BPVEC treated with hydrogen peroxide, vitamin E increased remarkably cell viability compared with control after BPVEC were treated with $15{\mu}M$ hydrogen peroxide for 6 hours. From these results, it is suggested that ROS has cytotoxicity on cultured BPVEC and oxygen radical scavenger such as vitamin E is very effective in prevention of oxidative stress-induced cytotoxicity.

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현장활동 소방공무원의 인간공학적 유해요인 노출이 결근에 미치는 영향 (Effects of Fire Fighters' Absence Ergonomics Risk Factor Exposer)

  • 최서연;박동현
    • 대한안전경영과학회지
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    • 제16권3호
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    • pp.101-110
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    • 2014
  • This study tried to identify the effects of ergonomic risk factors for absence from work of fire fighters in Korea. A self-administered questionnaire was prepared for this study. The questionnaire consisted of several parts such as 'general information', 'work-related factors', 'physical & chemical risk factors', 'ergonomic risk factors', and 'absence information'. A total of 7,098 fire fighters participated in this study. The data obtained from the survey was mainly analyzed by logistic regression. A total of 856 out of 7,098 fire fighters experienced absence from work. The risk factors such as gender, age, marital status, education level, total work year, work area. position, job rotation, noise, dust, organic solvent, skin contact with chemical substance, toxic waste, regional vibration, manual material handling, continuous standing posture, awkward working posture were associated with absence from work. Specifically, awkward working posture and manual material handling from ergonomic risk factors were major risk factors for absence from work.

자동차 엔진룸용 전장품 유무연 솔더 접합부의 열화특성 (Degradation Characteristics of Eutectic and Pb-free Solder Joint of Electronics mounted for Automotive Engine)

  • 김아영;홍원식
    • Journal of Welding and Joining
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    • 제32권3호
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    • pp.74-80
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    • 2014
  • Due to environmental regulations (RoHS, WEEE and ELV) of the European Union, electronics and automotive electronics have to eliminate toxic substance from their devices and system. Especially, reliability issue of lead-free solder joint is increasing in car electronics due to ELV (End-of-Life Vehicle) banning from 2016. We have prepared engine control unit (ECU) modules soldered with Sn-40Pb and Sn-3.0Ag-0.5Cu (SAC305) solders, respectively. Degradation characteristics of solder joint strength were compared with various conditions of automobile environment such as cabin and engine room. Thermal cycle test (TC, $-40^{\circ}C$ ~ ($85^{\circ}C$ and $125^{\circ}C$), 1500 cycles) were conducted with automotive company standard. To compare shear strength degradation rate with eutectic and Pb-free solder alloy, we measured shear strength of chip components and its size from cabin and engine ECU modules. Based on the TC test results, finally, we have known the difference of degradation level with solder alloys and use environmental conditions. Solder joints degradation rate of engine room ECU is superior to cabin ECU due to large CTE (coefficient of thermal expansion) mismatch in field condition. Degradation rate of engine room ECU is 50~60% larger than cabin room electronics.

Decomposition of PVC and Ion exchange resin in supercritical water

  • Lee, Sang-Hwan;Yasuyo, Hosgujawa;Kim, Jung-Sung;Park, Yoon-Yul;Hiroshi, Tomiyasu
    • 한국환경과학회:학술대회논문집
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    • 한국환경과학회 2005년도 봄 학술발표회지 제14권(제1호)
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    • pp.267-271
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    • 2005
  • This experiment was carried out at 450"C, which is relatively lower than the temperature for supercritical water oxidation (600-650$^{\circ}C$). In this experiment, the decomposition rates of various incombustible organic substances were very high. In addition, it was confirmed that hetero atoms existed in organic compounds and chlorine was neutralized by sodium(salt formation).However, to raise the decomposition rate, relatively large amount of sodium nitrate(3-4 times the equivalent weight) was required. When complete oxidation is intended as in the case with PCB, the amount of oxidizer and decomposition cost is important. But when vaporization reduction is required as in the case with nuclear wastes, the amount of radioactive wastes increases instead. But as can be seen in the result of XRD measurement, unreacted sodium nitrate remained unchanged. If oxidation reaction of organic substance simply depends on collision frequency, unreacted sodium nitrate can be recovered and reused, then oxidation equivalent weight would be sufficient. In the gas generated, toxic gas was not found. As the supercritical water medium has high reactivity, it is difficult to generate relatively low energy level SO$_{X}$, and NO$_{X}$.

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프로바이오틱스 Enterococcus faecium CKDB003의 항생제 내성 및 안전성 평가 (Antibiotic Resistance and Safety Assessment of Enterococcus faecium CKDB003 for Using as Probiotics)

  • 김한준;강순아
    • 한국식품영양학회지
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    • 제33권3호
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    • pp.223-236
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    • 2020
  • In this study, a safety evaluation was conducted to confirm if the Enterococcus faecium CKDB003 strain obtained by selection from a mixed fermentation of fruit and milk is suitable for use as a probiotic. The MIC value for the 10 antibiotics specified in the EFSA guidance was below the acceptable cut-off value. The antibiotic resistance genes aac(6')-li, eatAv, and msr(C) exist by whole genome sequencing, but are in the chromosome and not in the plasmid, thus confirming that there is no possibility of transmission to other microorganisms. It was confirmed that cytolysin (cylA, cylB, cylI, cylL-l, cylL-s, cylM, cylR1, cylR2), aggregation substance (asa1, asp1), collagen adhesion (ace), enterococcal surface protein (esp), endocarditis antigen (efaA), hyaluronidase (hyl) and gelatinase (gelE) were not present in the genome by examining the genes of factors related to virulence. Also, the biochemical analysis showed no toxic enzyme activities, and no virulence genes were detected by the PCR method. Thus, the E. faecium CKDB003 strain can be safely used as a health functional food probiotic, based on the results of the safety assessment.