• Journal of Pharmacopuncture
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• v.6 no.1
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• pp.61-66
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• 2003

In order to study the effects of Moschus Herbal-acupuncture on hyperlipidemia, we divided the rats into three groups(Normal group, Control group & Sample group) and performed the experimental research. Hyperlipidemia rats were induced by Triton WR-1339(150mg/kg) for 3days. Sample group was injected Moschus Herbal-acupuncture 0.1 ml/200g for 3 days and control group was injected equal dose of saline. And then we measured the amount of serum total cholesterol, triglyceride, phospholipid and HDL-cholesterol. The results were as follows : 1.Moschus Herbal-acupuncture showed decreasing effects on total cholesterol, triglyceride and phospholipid levels in serum significantly(p<0.05). 2.Moschus Herbal-acupuncture showed increasing effects on HDL-cholesterol level in serum significantly(p<0.05). According to the above results, Moschus Herbal-acupuncture showed significant decreasing effects on hyperlipidemia and it is considered that it is appropriate to apply for hyperlipidemia.

• The Journal of Internal Korean Medicine
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• v.15 no.1
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• pp.45-59
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• 1994

The present experiments were designed to investigate the effect of Ijntang, Sagoonjatang, and Yuggoonjatang on the hyperlipidemia induced rabbit. In order to control the precise chemical and physical condition, the experimental rabbits were supplied with calory limited food. The Hyperlipidemia rabbits were induced by oral administration of cholesterol (250mg/kg) for 4 weeks. The results were as followings : 1. The hyperlipidemia (control) group increased the concentration of serum glucose to $204.1{\pm}2.63\;mg/dl$ at the 4th. week, however, the other drug administrated groups such as Ijintang, Sagoonjatang, and Yuggoonjatang decreased significantly. 2. The control group increased the concentration of serum totalcholesterol to $299.0{\pm}4.18\;mg/dl$ at the 4th. week, however, the other drug administrated groups Ijintang, Sagoonjatang, and Yuggoonjatang decreased significantly. 3. The control group increased the concentration of serum total lipid to $429.1{\pm}1.72\;mg/dl$ at the 4th. week, however, the other drug administrated groups such as Ijintang, Sagoonjatang, and Yuggoonjatang decreased significantly. 4. The control group increased the concentration of serum triglyceride to $149.3{\pm}3.01\;g/dl$ at the 4th. week, however, the other drug administrated groups such as Ijintang, Sagoonjatang, and Yuggoonjatang decreased significantly. 5. The control group increased the concentration of serum HDL-cholesterol to $83.0{\pm}1.09$\;mg/dl$ at the 4th. week, and, the other drug administrated groups such as Ijintang, Sagoonjatang, and Yuggoonjatang increased significantly. 6. The lipid deposition to the aortic endothelium decreased more at the Yuggoonjatang group than the other groups. According to the above experimental results, Yuggoonjatang is assumed to have a more curative effect against hyperlipidemia than the other drug such as Ijintang and Sagoonjatang.

• Korean Journal of Food Science and Technology
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• v.40 no.1
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• pp.96-100
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• 2008

Pungent oils are fat sources that determine the taste, flavor, and satiety of foods. They are also energy sources and regulators of lipid metabolism in humans. The present study was performed to evaluate the effects of red pepper (Capsicum annuum L.) seed oil (RPO) and sancho (Zanthoxylum schinifolium) seed oil (SCO) as pungent oils on the lipid profiles of rats fed on hypercholesterolemic diets (0.12% cholesterol), as compared to common soybean oil (SBO). There were large differences in the n-6/n-3 fatty acid ratios of the experimental oils (SBO: 8.8, SCO: 1.2, RPO: 70.1). Serum cholesterol concentrations were higher in the RPO groups than in the other groups; whereas ratios of HDL-cholesterol/total cholesterol were lower in the RPO groups. On the other hand, liver cholesterol levels were markedly higher in the SCO groups than in the RPO groups, with the SBO groups having intermediate levels; these largely reflected cholesterol ester content differences in the rat livers. It is possible that the different serum cholesterol responses observed in the RPO and SCO groups might have been related to differences in the n-6/n-3 fatty acid ratio rather than the polyunsaturated fatty acids/saturated fatty acids ratio. Serum triacylglycerol concentrations were lower in the SCO groups as compared to the other groups. Overall, the results showed a hypocholesterolemic effect for sancho seed oil as compared to red pepper seed oil in rats fed diets containing 0.12% cholesterol.