• Journal of Nutrition and Health
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• v.33 no.4
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• pp.374-385
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• 2000

The purpose of the present study was to investigate the effect of Korea leek on plasm lipids and platelet aggregation in hypercholesterolemic rats fed different dietary fat. Sprague-Dawley rats were fed with hyperlipidemic diet for 4 weeks in order to induce hyperlipidemia, followed by the feeding of experimental diets for additonal 4 weeks. We used three kinds of lipid(perilla oil, corn oil and lard). Korean leek of experimental diets was prepared by drying and milling. Powdered Cellulose and powdered Korean leek were added to experimental diets at the level of 5% (w/w). Serum concentrations of total lipid, total triglyceride, total cholesterol and LDL-cholesterol decreased in the order of perilla oil, corn oil and lard. Korean leek significantly decreased total lipid, total cholesterol, LDL-cholesterol, platelet count, prothrombin time, and platelet aggregation in rats fed a lard diet. The present observation indicates that Korean leek might be helpful for the prevention and threapy of hyperlipidemia and platelet aggregation.

• The Korean Journal of Food And Nutrition
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• v.20 no.2
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• pp.143-149
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• 2007

To examine the effects of pomegranate on cerebral blood flow and obesity, we observed regional cerebral blood flow in normal rats, as well as body weight, serum total cholesterol, serum HDL-cholesterol, serum LDL-cholesterol, serum triglycerides, serum total lipids, serum phospholipids and serum free fatty acid levels in rats fed a high fat diet. The results were as follows. Pomegranate seed extract significantly increased regional cerebral blood flow and the peel extract increased regional the cerebral blood flow in a dose dependent manner. In addition, the pomegranate extracts(seed, peel, juice) decreased body weight, serum total cholesterol, serum LDL-cholesterol, serum triglycerides, serum total lipids, serum phospholipids and serum free fatty acid levels, and increased serum HDL-cholesterol in the rats fed a high fat diet. More specially the seed extract significantly decreased serum total cholesterol, serum triglycerides and serum phospholipid levels.

• Applied Biological Chemistry
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• v.29 no.4
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• pp.346-351
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• 1986

This study was carried out to investigate the changes in bound, free, and neutral lipid components of malt during malting, two-rowed barley. During malting, the temperature and relative humidity were $17^{\circ}C$ and 80%, respectively. The content of free lipids in both two-rowed barley and their malt was much higher than that of bound lipids. Decrease in the content of free lipids during malting was more prominent than that of bound lipids. The content of neutral lipids was 21.0mg/g-d. w. out of 27.9mg/g-d. w. of total lipids extracted from two-rowed barley. The content of neutral lipids decreased during malting. Triglyceride, free fatty acid and sterol ester were the principal components of neutral lipids. The content of triglyceride decreased during malting, but the content of free fatty acid and sterol ester increased. Linoleic, palmitic, oleic and linolenic acid were the principal fatty acid of free and bound lipids. The content of palmitic acid in free lipids increased during malting, but that of bound lipids decreased. The content of oleic acid in free lipids decreased. The principal fatty acids of neutral lipids were similar to those of free lipids. The content of palmitic acid increased during malting, but that of linoleic and stearic acid decreased.

• Korean Journal of Pharmacognosy
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• v.27 no.4
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• pp.397-407
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• 1996

This study was attempted to investigate the effect of Composite Preparation (Sam Whang Sasim-Tang: SWST, Whang Ryun Haedok-Tang: WRHT) on the activities of GOT and GPT, the content of total lipids, triglyceride, total cholesterol. Phospholipid and ${\beta}-lipoprotein$ in the serum, and the change ratio of body and liver weight in the experimentally induced hyperlipemic rats, making use of the extract 150, 200, 300 and 500 mg/kg p.o. Significant test was performed by comparision with the values of corresponding experimentally hyperlipemic rats. The activities of S-GPT was significantly decreased in all dose of SWST and WRHT respectively. The activities of S-GPT was significantly decreased in dose of SWST 500 mg/kg and in all dose of WRHT respectively. The content of total lipids, triglyceride, total cholesterol and phospholipids were significantly decreased in all dose of two the extract. The rate of decrease on total lipids and triglyceride were remarkable in dose of SWST 300, 500 mg/kg and WRHT 200, 500 mg/kg, and then the content of total cholesterol was more remarkable in dose SWST 300, 500 mg/kg, and WRHT 150, 300 mg/kg, and the content of phospholipids was more remarkable in dose of the extract 150, 200 and 300 mg/kg. The content of ${\beta}-lipoprotein$ was significantly decreased in dose of WRHT 150, 200 and in all dose of SWST. Increase ratio of the body and liver weight were significantly decreased in dose of two the extract 300, 500 mg/kg respectively.

• Journal of Nutrition and Health
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• v.24 no.3
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• pp.157-165
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• 1991

The purpose of this study was to investigate differences in body fat distribution between normal and obese subjects and the relationship between risk factors(fasting blood sugar, blood pressure. fasting serum lipids) and obesity. Measurements of height. weight, skinfold thickness. body circumference. percent body fat. blood pressure, fasting blood sugar and serum lipids were made and a dietary survey was performed on 120(Males 61. Females 59) adult subjects. 1) Among the female subjects, the obese group appeared to have significantly higher centrality of body fat than the normal group. Obese groups of both sexes appeared with higher blood pressure than normal groups. No differences in daily average nutrient intake, fasting blood sugar and fasting serum lipids concentrations were observed between obese and normal groups. 2) In males. the serum triglyceride concentration was observed to have a significantly positive correlation to body weight, body mass index and body circumference, additionally concentrations of total cholesterol and LDL-cholesterol were observed to have significantly positive correlations to the skinfold thickness. but the ratio of HDL-cholesterol/total cholesterol was observed to be significantly negatively correlated to the skinfold thickness. 3) In females. the obese group consumed about 47% of total energy intake at lunch. whereas the normal group consumed about 29% . The food habit score of males appeared to be negatively related to body weight, percent ideal body weight. But the food habit score of females appeared to be negatively related to percent body fat(r=-0.32, p<0.05) .

• Korean Journal of Adult Nursing
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• v.18 no.5
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• pp.809-818
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• 2006

Purpose: The purpose of this study was to evaluate the effect of antioxidant vitamins and magnesium supplementation on fasting blood glucose and lipids in patients with type 2 diabetes. Methods: This study is a unequivalent control group pretest-posttest design. Seventyone subjects with type 2 diabetes who were recruited from home visiting clients of a public health center, completed the trial. The experimental group entered a 12-week treatment period with antioxidant vitamins and magnesium and the control group with no antioxidant vitamins and magnesium. Results: Serum level of fasting blood glucose decreased from $134.7mg/d{\ell}$ to $125.0mg/d{\ell}$ and total-cholesterol decreased from $215.5mg/d{\ell}$ to $198.2mg/d{\ell}$ in the experimental group. No changes in fasting blood glucose and total-cholesterol were demonstrated in the control group. Conclusions: A short-term supplementation with antioxidant vitamins and magnesium can reduce fasting blood glucose and total-cholesterol in patients with type 2 diabetes. The continuous effect of this supplementation and the beneficial effect on the prevention of diabetes complication still needs to be demonstrated.

• Journal of the Korean Society of Food Science and Nutrition
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• v.15 no.4
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• pp.17-23
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• 1986

This study was designed to observe the effect of Undaria Pinnatifida (U. P.) Powder on serum and liver lipids concentration in rats. Adult male rats of Sprague-Dawley strain were divided into four diet groups: one control diet and the other three diets in which U.P. powder was mixed with the control diet at the rate of 1%, 2% and 3% respectively. The results of the above observation were as follows : Serum and liver total lipids in 3% U.P. group were lower an those in control group at the 6th week. There was no difference in serum and liver total cholesterol among the diet groups. Serum HDL-cholesterol and HDL-cholesterol per total cholesterol ratio in 3% U.P. group were higher than those in control group at the 3rd and 6th week. Serum triglyceride in 3% U.P. group was significantly lower than that in control group at the 3rd week. Serum phospholipid in 1% U.P. and 3% U.P. group was significantly lower than that in control group at the 3rd week, but there was no difference among them at the 6th week.

• Korean Journal of Clinical Laboratory Science
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• v.38 no.2
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• pp.105-110
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• 2006

This study was carried out to establish the normal values of serum lipids by age and sex for healthy adults and the frequency of dyslipidemia as a risk factor of coronary atherosclerosis. Total cholesterol, triglyceride, and HDL-cholesterol were measured for 14,485 average adults (8,712 males and 5,773 females) aged 20 to 69 years and analyzed using the auto-analyzer Hitach 7600 in enzyme method. Mean values of total cholesterol, LDL-cholesterol and atherogenic index were higher in men than in women at the ages of 20-40 years but significantly higher in women than in men in the age group of 60 years. Theses findings suggest that the mean concentrations of total cholesterol, triglyceride and LDL-cholesterol in men and women vary with age. The frequency of hypercholesterolemia ($${\geq_-}200mg/dL$$) in men and women was about 31.4% and increased with age.

• Applied Biological Chemistry
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• v.29 no.2
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• pp.122-129
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• 1986

The lipid compositions of corns produced in Korea were analyzed. Free and bound lipids of the corn kernels were fractionated, quantitated and compared by silicic acid column, thin layer and gas liquid chromatography. Corn kernels contained 5.02% total lipids, which is consisted of 4.09% free lipids and 0.93% bound lipids. Free lipids comprised of 89.61% neutral lipids, 3.75% glycolipids and 6.40% phospholipids, while bound lipids contained 14.26% neutral lipids, 46.06% glycolipids and 37.18% phospholipids. In the neutral lipids of free lipids, triglycerides were predominant (67.68%) and minor components such as esterified sterols, free sterols, free fatty acids, 1,3-diglycerides, 1,2-diglycerides were present. But in the neutral lipids of bound lipids, esterified sterols were not present and the contents of triglycerides were lower (47.68%) and free fatty acids were higher than those of free lipids. Among the phospholipids in free and bound lipids, phosphatidyl choline and phosphatidyl serines and phosphatidyl inositols were also present as minor components. The major fatty acids in the three lipid classes were linoleic, oleic and palmitic acids.

• Journal of Nutrition and Health
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• v.17 no.4
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• pp.253-261
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• 1984

The effect of fiber sources on lipid metabolism was investigated in relation to the level of dietary fat. After rats were fed each diet for 4 weeks, all animals were sacrificed to collect the liver, and blood samples by heart puncture. Total lipid, total cholesterol, phospholipid and HDL- cholesterol were determined in serum. Total lipid and total cholesterol were also determined in liver. These results were compared with the histochemical appearances by the method of Oil red-O staining. Higher level of fat in the diet appeared to increase the total lipid levels in serum and more fat in the liver cells were shown from the high fat diet judging from the E.M. pictures. Phospholipid concentration in serum was greater in the rats of high fat groups than those of the control or non-fat groups. High fat level caused to decrease the HDL- cholesterol concentration in serum. Pectin decreased serum and liver lipids and the deposit of fat in the liver cells. HDL-cholesterol levels in serum was increased by pectin. Whereas the cellulose supplementation had no effect to reduce serum and liver total lipid levels, and cellulose did not decreased the deposit of fat in the liver cells. From these results, it is concluded that dietary fat levels led to changes in the lipid metabolism of rats and pectin may exhibit a lowering total lipid contents in serum and liver. Cellulose may slightly elevate serum and liver levels, or have no lowering effect.