• Journal of Nutrition and Health
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• v.27 no.2
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• pp.119-126
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• 1994

The effect of diets(high fat, high fat high energy, pectin, cellulose) on adipocyte of epididymal fat pads were investigated in 70 male rats for 8 weeks. The rats were assigned to a control(C), high fat(HF) and high fat high energy(HFHE) group for 4 wks. During the next 4 wks, reassigned to one of three treatments (high fat, pectin supplemented, cellulose supplemented) in the HF group and one of three treatment (high fat high energy, pectin, cellulose) in the HFHE group. Therefore, the total experimental groups were 7 (C, HF, HF-P, HF-C, HFHE, HFHE-P, HFHE-C). Parameters evaluated and compared for each diet were body weight, total energy intake, feed efficiency ratio and weight changes in epididymal fat pads. The results are summarized as follows ; 1) There was no significant difference in body weight gain among the groups. 2) Total energy intake was higher in the C group than other groups. 3) Feed efficiency ratio (F.E.R) of the HF and HFHE groups were greater than C group(2, 4 weeks). However, there were no significant differences between the HF and HFHE groups. 4) Epididymal fat pads(EFP 100g/B.W) of the FH and HFHE groups were higher than C group (2, 4 weeks). However, there were no significant differences between the HF and HFHE groups. There was no significant difference in weight gain of epididymal fat pads among the groups(8 weeks). 5) Cell number and cell size of epididymal fat pads of the HF and HFHE groups were higher than the C group. The pectin and the cellulose supplementation groups decreased cell number and cell size of epididymal fat pads. Especially, the pectin supplementation group decreased than the cellulose supplementation in HFHE group. Therefore, we can concluded that the HF and the HFHE diet has no effect on the epididymal fat pads.

• Preventive Nutrition and Food Science
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• v.11 no.3
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• pp.210-217
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• 2006

This study was performed to investigate effects of the experimental mixture containing soybean peptides, L-carnitine and Garcinia Cambogia extract on body weight and lipid metabolism in rats. Male Sprague-Dawley rats (n=40) of eight weeks old were raised for four weeks with high fat diet (40% fat as calorie) to induce obesity. After induction of obesity, rats were feed control (C) diet, containing either 0.16% (+1D), 1.6% (+10D), 8% (+50D) of experimental mixture for eight weeks. Plasma aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activity and total protein and albumin concentration were not different among groups. The Body weight gain was significantly lower in experimental mixture diet group compared to control group. Weights of perirenal fat pad and epididymal fat pad in the +50D group were significantly lower than those in the +1D and +10D groups. Plasma total lipid and liver total cholesterol levels in the experimental groups were significantly lower than those in the control group. Fecal total lipid and total cholesterol excretions were highest in +50D group. These results suggest that the experimental mixture containing peptides, L-carnitine and Garsinia Canbogia extract is effective for reducing the body weight and adipose tissue weight which may be due to the modulation of lipid metabolism and the increased fecal excretion of lipid.

• Journal of the Korean Home Economics Association
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• v.33 no.6
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• pp.89-97
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• 1995

This study was undertaken to examine the correlations between dietary intakes or anthropometric parameters and the plasma lipid level. measurements of dali nutrients intake, body weight, height, body bass index, skinfold thickness, blood pressure, plasma total lipid, triglyceride and cholesterol were made to each of 124 healthy adult(25-59yrs) : 56 males and 65 females. The mean energy and nutrients intake, anthropometric parameters and plasma lipid levels were all in normal range. In females, the fat and protein intake, the amount and percents to total energy intake, had positive association with the plasma total lipid, but the energy percent from carbohydrate intake was correlated negatively. And body mass index positively correlated with plasma total lipid level, in male and female, Therefore we could postulated the dietary fat intake and body mass index affected to plasma lipid levels in normal conditions of healthy adult.

• Journal of Acupuncture Research
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• v.24 no.5
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• pp.67-88
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• 2007

Objectives : To present proper protocol as global standard- clinical study about acupuncture treatment, and to demonstrate effectiveness of Sa-am Acupuncture treatment for obesity. Methods : We randomly allocated participants to treatment group 1 and 2. The group 1 is treated by real acupuncture and the group 2 is treated by Kim Sham Acupuncture. We treated Bi-jang seung-gyeok (脾臟勝格) ; Daedon(LR1), EunBaek(SP1) Gyoung-geo(LU8) Sang-gu(SP5), to both group. Primary outcomes were measured by the Body Composition Analysis(Inbody. Korea). Secondary outcomes were measured by Blood Cholesterol, Triglyceride, HDL, LDL Cholesterol. Results : After treatment, the group 1 shown significant weight loss that analysed by Kruskal-Wallis certification, but didn't show notable change in body fat, total cholesterol, triglyceride, HDL cholesterol, LDL cholesterol. Group 2 didn't show significant change in body weight, body fat, triglyceride, HDL cholesterol, LDL cholesterol, but total cholesterol was notably decreased. Controled group was not changed in body weight, body fat. Aftter treatment, 3 groups didn't show significant change in body weight, body fat, triglyceride, HDL cholesterol, LDL cholesterol, total cholesterol.

• Journal of Korean Medicine Rehabilitation
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• v.18 no.4
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• pp.189-201
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• 2008

Objectives : This study was performed to find out the relationships between abdominal fat and eating attitude in obese climacteric women. Methods : 42 obese climacteric women were recruited in August 2007. Anthropometry has been done and abdominal fat distribution had been assessed by CT scan at the level of L4-5 and eating attitude was measured using Korean Eating Attitude Test-26. Results : There were significant correlations between body mass index, percent of body fat and eating attitude. Total abdominal fat and visceral fat also increased with KEAT-26. Conclusions : There were relationships among eating attitude total fat, abdominal fat and visceral fat in obese climacteric women.

• Journal of Korean Medicine for Obesity Research
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• v.1 no.1
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• pp.33-42
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• 2001

Objectives: This study was to investigate the reductive effects of oriental medicine on the body fat and abdominal obesity, Methods: The subject were selected among the patients who were treated with 4weeks total program, visited our obesity clinic from October 1999 to August 2000, We practiced combined therapy such as herbal medicine, acupuncture therapy, moxibution therapy, negative therapy, auricular acupuncture, electrolipolysis, colon hydrotherapy, heat therapy, Chuna therapy, low-calorie diet teaching, exercise teaching, and correcting life style for 4 weeks. Results and Conclusion: 1. Body weight, RBW, and BMI were significantly reduced each by 5.4kg, 10.4% and $2.2kg/m^2$ (p<0.01). 2. % Body fat was significantly reduced by 3.3%. Fat mass was reduced by 4.0kg(17.0%) and soft lean mass was reduced by 1.5kg(3.7%), thus it was acknowledged that fat mass was significantly reduced compared to soft lean mass by oriental medicine treatment for obesity. 3. WHR was significantly reduced by 0.02. Waist circumference was reduced by 6cm(6.6%) and hip circumference was reduced by 4.5cm(4.6%), thus it was acknowledged that waist fat was significantly reduced compared to hip circumference by oriental medicine treatment for obesity.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.3
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• pp.575-579
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• 2008

The purpose of this study was to investigate the effects of Astragali Radix on the diet-induced hyperlipidemia in rats. Hyperlipedemia was induced in rats with high fat diet. Rats were divided into 4 groups, normal group(supplied enough water and feeds only), high fat diet administered group(supplied high fat diet for 4 weeks, Control group) and Astragali Radix administered group(supplied high fat diet and Astragali Radix lyophilization extract for 4 weeks, 178.6 mg/kg(rat) in sample A, 297.8 mg/kg(rat) in sample B). Body weight, liver weight and serum lipid levels were evaluated. The water extract of Astragali Radix decreased body weight, liver weight, total cholesterol, LDL-cholesterol, triglyceride and phospolipid in high fat diet induced hyperlipidemia in rats, and increased HDL-cholesterol.

• Journal of Korean Biological Nursing Science
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• v.14 no.4
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• pp.231-238
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• 2012

Purpose: The purpose of this study was to investigate body composition, blood pressure, blood lipids, and glucose according to obesity degree by body fat percentage in female university students. Methods: A total of 231 subjects were participated between July and December 2010. The anthropometric measures and blood analyzer were used. Data were analyzed using descriptive statistics, ANOVA, and Pearson's correlation coefficient with SPSS 18.0. Results: Percentage of body fat (PBF)-defined obesity had higher prevalence than body mass index (BMI)-defined obesity. Weight, BMI, PBF, fat mass, Waist to hip ratio (WHR), Systolic blood pressure (SBP), Diastolic blood pressure (DBP) in obesity group were higher than normal group and Soft lean mass and Low density lipoprotein (LDL) in obesity group were lower than normal group. There were significant correlations between PFB, SBP, DBP, Triglyceride (TC), High density lipoprotein (HDL), and LDL. Conclusion: In conclusion, when screening for obesity in female university students, body fat should be considered. It is needed to develop obesity management program according to obesity degree and to identify the effectiveness.

• Journal of Acupuncture Research
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• v.24 no.5
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• pp.113-125
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• 2007

Objectives : This research was performed to investigate the effect of herbal acupuncture(Raphanus sativus) at Bisu($BL_{20}$) on weight gain, food intake, food efficiency, serum of lipid concentrations, liver function and HDL to total cholesterol ratio of rats fed high fat diet for 5weeks. Methods : Experimental groups were divided into high fat diet group(Control), high fat diet and saline in $BL_{20}$ treated group(Saline), high fat diet and Raphanus sativus-herbal acupuncture in $BL_{20}$ treated group(RHA-1, 0.058mg/ml/g), high fat diet and Raphanus sativus-herbal acupuncture in $BL_{20}$ treated group(RHA-2, 0.029mg/ml/g), high fat diet and Raphanus sativus-herbal acupuncture in $BL_{20}$ treated group(RHA-3, 0.011mg/ml/g), Herbal acupuncture was bilaterally treated at 0.2cc per 4days, total 14 times in 56days. Results : Body weight and food efficiency were decreased in saline, RHA-1, RHA-2. Feed intake was increased in saline, RHA-1, RHA- 2, RHA- 3. The level of serum total cholesterol was decreased in saline, RHA-1. The level of serum HDL-cholesterol, LDL-cholesterol were not significant. The level of serum triglyceride, Total Bilirubin were decreased in saline, RHA-1, RHA-2, RHA-3.The level of serum AST was decreased in RHA-1. But the level of serum ALT was increased in RHA-1. The level of atherogenic index was decreased in saline, RHA-1. The level of HTR was increased in saline, RHA-1. Conclusions : Raphanus sativus-herbal acupuncture in Bisu($BL_{20}$) can control body weight, feed intake and feed efficency ratio, total cholesterol, total bilirubin, and prevention cardiovascular risk.

• Journal of Nutrition and Health
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• v.10 no.4
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• pp.10-18
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• 1977

Activities of lipoprotein lipase (LPL) and hormone-sensitive lipase (HSL) in adipose tissue, accumulation of carcass fat, and serum triglyceride have been determined in meal-fed (MF) and ad libitum-fed (AD) rats. At each feeding frequency, the animals received diets providing total fat as 15% or 30% of calories and polyunsaturated fatty acids (PUFA) as 2.5% or 11% of calories. The food intake of the MF rats was 75% of that consumed by the AD rats but MF rat utilized their food more efficiently, as evidenced by weight gain per 100 Kcal consumed. Meal feeding, as contrasted to ad libitum feeding, resulted in greater activities of both LPL and HSL. This suggested a higher turnover of fat in the adipose tissue of MF rats. In AD rats, body fat was significantly correlated with LPL and the ratio of LPL/HSL. Meal feeding significantly increased the ratio of LPL/HSL, indicating a greater capacity for energy storage and fat deposition in the MF rat. However, at the limited caloric intake, MF rats failed to realize this potential; there was no significant difference in percentage of body fat at the two feeding frequencies. Body fat deposition was greater in rats fed the 30% fat diet, as compared with the 15% diet, regardless of the rate of food ingestion. This was coupled with a higher ratio of LPL/HSL. The significant correlation of serum triglycerides with body fat and with the ratio of LPL/HSL in AD rats suggests that LPL activity and fat deposition may be controlled by the concentration of circulating triglycerides. Both serum triglycerides and adipose LPL activity were significantly reduced when the diet contained high levels of PUFA. The percentage of body fat was also lower in animals whose intake of PUFA was high.