• The Korean Journal of Physiology and Pharmacology
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• v.20 no.6
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• pp.605-611
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• 2016

Ketamine is an anesthetic with hypertensive effects, which make it useful for patients at risk of shock. However, previous ex vivo studies reported vasodilatory actions of ketamine in isolated arteries. In this study, we reexamined the effects of ketamine on arterial tones in the presence and absence of physiological concentrations of 5-hydroxytryptamine (5-HT) and norepinephrine (NE) by measuring the isometric tension of endothelium-denuded rat mesenteric arterial rings. Ketamine little affected the resting tone of control mesenteric arterial rings, but, in the presence of 5-HT (100~200 nM), ketamine ($10{\sim}100{\mu}M$) markedly contracted the arterial rings. Ketamine did not contract arterial rings in the presence of NE (10 nM), indicating that the vasoconstrictive action of ketamine is 5-HT-dependent. The concentration-response curves (CRCs) of 5-HT were clearly shifted to the left in the presence of ketamine ($30{\mu}M$), whereas the CRCs of NE were little affected by ketamine. The left shift of the 5-HT CRCs caused by ketamine was reversed with ketanserin, a competitive 5-$HT_{2A}$ receptor inhibitor, indicating that ketamine facilitated the activation of 5-$HT_{2A}$ receptors. Anpirtoline and BW723C86, selective agonists of 5-$HT_{1B}$ and 5-$HT_{2B}$ receptors, respectively, did not contract arterial rings in the absence or presence of ketamine. These results indicate that ketamine specifically enhances 5-$HT_{2A}$ receptor-mediated vasoconstriction and that it is vasoconstrictive in a clinical setting. The facilitative action of ketamine on 5-$HT_{2A}$ receptors should be considered in ketamine-induced hypertension as well as in the pathogenesis of diseases such as schizophrenia, wherein experimental animal models are frequently generated using ketamine.

• The Journal of the Acoustical Society of Korea
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• v.24 no.2
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• pp.117-126
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• 2005

This study investigates the prosodic characteristics of Korean through the analysis of a large database. One female and one male speakers each read 650 sentences and they were segmentally and prosodically labeled. Statistical analyses were done on these utterances regarding the tonal pattern and the size of prosodic units, correlation between the size of higher level prosodic units and the number of lower level prosodic units. and the slope and F0 of the falling and rising contours of an accentual phrase. The results showed that the duration and the number of words and syllables of a prosodic unit were significantly different not only between speakers but also between its positions within a higher level prosodic nit. The munber of a prosodic unit showed a high correlation with the duration and the number of syllables of its higher level units. The slope of the falling contour within an accentual phrase was inversely Proportional to the number of its syllables. The slope was different depending on the first tone type of an accentual phrase, which could be explained with the F0 rising and the different amount of rising between tones when an accentual phrase starts with an H tone. The slope of the falling contour across an accentual phrase boundary showed a constant and larger value compared to one within an accentual phrase. The rising contours in the beginning and end of an accentual Phrase were similar in their slopes but they differ in the amount of F0 change : the former showed a larger amount of change. The slope of the rising contour which forms an accentual Phrase on its own was inversely Proportional to the number of its syllables.

• Applied Biological Chemistry
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• v.51 no.2
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• pp.102-107
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• 2008

Nitric oxide (NO) is a potent antihypertensive and vasodilator which plays an important role in regulating vascular tones. In this study, we investigated the effects of adventitious root extracts of wild ginseng on NO production and NO linked physiological activities. When human endothelial cell line (ECV304) was incubated with either water extracts of wild ginseng adventitious root (WE) or aqueous fraction of butanol extracts of wild ginseng adventitious root (ABE), considerable amounts of NO were released by the cells. The level of endothelial nitric oxide synthase (eNOS) expression was unchanged and about 6% of the angiotensin converting enzyme (ACE) was inhibited with treatment of ABE. The vasodilating activities of pulmonary artery rings in response to different doses of extracts were shown as 44.8% and 91.3% in 2.5 mg/ml WE and 0.1 mg/ml ABE, respectively. The blood pressure lowering effect was observed from the oral administered spontaneously hypertensive rat (SHR) with the lowest blood pressure (154.5${\pm}$8.6 mmHg) after 8 h. The blood pressure was recovered to the initial level after 24 h.

• Journal of Pharmacopuncture
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• v.18 no.4
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• pp.26-31
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• 2015

Objectives: This study used semiology based on traditional Chinese medicine (TCM) to investigate vital energy (Qi) behavior in women with abdominal myofascial pain syndrome (AMPS). Methods: Fifty women diagnosed with chronic pelvic pain (CPP) secondary to AMPS were evaluated by using a questionnaire based on the theories of "yin-yang," "zang-fu", and "five elements". We assessed the following aspects of the illness: symptomatology; specific location of myofascial trigger points (MTrPs); onset, cause, duration and frequency of symptoms; and patient and family history. The patients tongues, lips, skin colors, and tones of speech were examined. Patients were questioned on various aspects related to breathing, sweating, sleep quality, emotions, and preferences related to color, food, flavors, and weather or seasons. Thirst, gastrointestinal dysfunction, excreta (feces and urine), menstrual cycle, the five senses, and characteristic pain symptoms related to headache, musculoskeletal pain, abdomen, and chest were also investigated. Results: Patients were between 22 and 56 years old, and most were married (78%), possessed a elementary school (66%), and had one or two children (76%). The mean body mass index and body fat were 26.86 kg/cm2 (range: 17.7 - 39.0) and 32.4% (range: 10.7 - 45.7), respectively. A large majority of women (96%) exhibited alterations in the kidney meridian, and 98% had an altered gallbladder meridian. We observed major changes in the kidney and the gallbladder Qi meridians in 76% and 62% of patients, respectively. Five of the twelve meridians analyzed exhibited Qi patterns similar to pelvic innervation Qi and meridians, indicating that the paths of some of these meridians were directly related to innervation of the pelvic floor and abdominal region. Conclusion: The women in this study showed changes in the behavior of the energy meridians, and the paths of some of the meridians were directly related to innervation of the pelvic floor and abdominal region.

• Korean Journal of Ichthyology
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• v.12 no.1
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• pp.38-45
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• 2000

Depending on the fish species the vascular tone is distinctively regulated by numerous vasoactive substances. In most fish species the regulatory role of autonomic neurotransmitters and other vasoactive substances are not well defined. This research was designed to delineate the regulatory role of various endogenous autonomic neurotransmitters known to be important in mammalian vascular systems on isolated Israeli carp ventral aorta. Acetylcholine(ACh) contracted the aorta regardless of the pre-existing level of vascular tone, and the contraction was almost completely abolished by a cholinergic-muscarinic antagonist atropine. Endogenous, multiple receptor ($\alpha$ and $\beta$)-acting adrenergic agonist epinephrine (Epi) relaxed the vessel in the presence and absence of the pre-existing tones. Another endogenous multiple receptoracting agonist norepinephrine (NE) weakly contracted the aorta in non-preconstrcted state, but the response was reversed to relaxation when preconstricted. Isoproterenol, ${\alpha}\;{\beta}$ adrenergic receptor agonist, was a potent vasodilator whereas an ${\alpha}_1$ agonist phenyephrine was a contractor. The ${\alpha}_2$ adrenergic receptor agonist clonidine has not any significant effect in altering the vascular tone. The vasorelaxing action of Epi, NE and isoproterenol was significantly attenuated by $\beta$ receptor antagonist propranolol. These results imply that ACh may primarily play a contractor role via muscarinic receptor activation while adrenergic agonists, Epi and NE, are relaxants through activation of $\beta$ adrenergic receptors in vivo.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.16 no.12 s.103
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• pp.1229-1238
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• 2005

OFDM(Orthogonal Frequency Division Multiplexing) communications system is very attractive for the high data rate wireless transmission. However, it may be distorted in the nonlinear HPA(High Power Amplifier) since OFDM signal has hish PAPR(Peak-to-Average Power Ratio). In this paper, a new method using control tone is studied for reducing the PAPR and we call it PCT(PAPR Control Tone) method. This proposed PCT method is to assign control tones for PAPR reduction at the predefined sub-carriers. After IFFT(Inverse Fast Fourier Transform) and PAPR calculation, the OFDM data signal of the lowest PAPR is selected to transmit. Unlike the conventional method, it can cut down the computational complexity because it does not require the transmission and demodulation process of side information about the phase rotation. Furthermore, if this method is made up in parallel configuration, it can solve the time delay problem so that it can be processed in real time processing. This proposed method is compared with the conventional selected mapping(SLM) technique. We find out the PAPR reduction performance and BER when the number of control tone is 6 and nonlinear HPA is considered.

• International Journal of Costume and Fashion
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• v.7 no.1
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• pp.49-61
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• 2007

The subject of study concerns the color characteristics of clothing/accessories from �Chosun�a nd modern Korea. It particularly focuses on the colors of the �Jeogori? traditional jacket) which represents Korean traditional clothing. Color data were collected from 353 woman�s �Jegori�s from �Chosun�a nd modern Korea and divided into the predominant colors & sub colors, and analyzed with HV/C and PCCS. According to the analysis, the representative the predominant color of 'Chosun Jeogori' for woman is YR, Y and side one is R, YR. The p, dp, sf, ltg colors are frequently found and the freshness of most of them is medium or low which shows a calm-feeling. The p, and ltg tones are often found as a the predominant color and p, dp are also often found as a the side color. In the 'Chosun Jeogori' for woman, the predominant colors and the side colors spread in a similar frequency and most of them have medium or low freshness of the color that shows a calm-feeling. The side color is one of the R colors and it shows characteristics of traditional coloring such as �Jajoo Goreum? Among the �Jeogori�f or modern women, the R, YR, Y, and B colors are often used for the single-color �Jeogori? the Y, GY, N, G colors are for the colorful �Jeogori? The P, lt, and b tons of the color are often used for a single-color �Jeogori�a nd the p, lt, and W are for the colorful �Jeogori? For the colorful �Jeogori? the side color have a high freshness which shows that a strong image was used frequently as the dp, s, dk tons of the color were often used. According to an analysis of the coloring, the predominant color and the side color of �Chosun Jeogori�a re applied to create a harmony of analogy & contrast in one aspect of Moon & Spencer�s view. It is found that the predominant color and the side color are similar or contrasting in one view of the color harmony, except that the traditional the �Jeogori�i s colored by ideological and symbolic meanings. The predominant color and the side color of modern the �Jeogori�a re complementary colors which are applied to the indistinct relationship or contrasting harmony in one aspect of Moon & Spencer�s view of the color harmony. The characteristics of the color as above show that traditional the �Jeogori�r egards the side color as both the harmony of the colors in general and also of symbolic meaning, while modern the �Jeogori�f or woman has a tendency toward a cultural transition and is mixed with new colors focusing more on its the predominant color than on the general harmony and character of ideological & traditional coloring.

• Journal of the Korean Society of Costume
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• v.58 no.2
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• pp.62-77
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• 2008

This study aims to analyze color characteristics centered by women's suit styles that represent masculinity remarkably. Through this, it figures out color's type and continuance availability as a representing tool to express masculinity to provide useful color information which can be applied effectively to various color planning. For this research, related images were collected among women's pants suits appeared in $2004{\sim}2006's$ Paris, London, New York and Milan collection F/W that are most similar to modern man's suit. Among them, the study analyzes 319 pictures where the features of masculinity were represented effectively. The referred color values were earned by converting $L^*a^*b^*$ values measured through the color extracting tool of Computer program (Adobe Photoshop CS) and color tone characteristic were analyzed by classifying 12 color PCCS and 5 achromatic colors. The result of the study are as follows: First, based on standard of color hue and tone, in terms of color hue, PB, YR, Y were frequently shown up but G, BG series were not found much after analyzing overall women's pants suit color characteristics shown in $2004{\sim}2006$ Paris, London, New York and Milan collection. Second, the color analysis about 3years of $2004{\sim}2006$ tells that achromatic colors have been most widely used in every year. In terms of color hue, PB, YR, Y series were appeared most popular and G, BG classes weren't appeared frequently. In addition, once looking at yearly color tone distribution trend, like overall color tone distribution result, Bk, w, dkg, g, p were highly used as sequential and b, v, dp, sf, ItGy series show low distribution level. And such a distribution level of low and high in frequency has been showed continuously as a similar style. Accordingly, through the study, as a tool to express masculinity in women's suit, achromatic colors like black and white series and PB, YR, Y series color were investigated as most popular uses. And as color tones, Bk, w, dkg, g, p were used frequently.

• Archives of design research
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• v.21
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• pp.99-106
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• 1997

There were the changes of shapes and color tones when the soil materials e.g. Blue-Porcelain, White-Porcelain, Bunchong, mixed A and B, mullite, Sanchong and Ongki - used by most domestic ceramic artists - were glazed at $ 950^{\circ}C,; 1200^{\circ}C,; 1250^{\circ}C,; 1280^{\circ}C,;1300^{\circ}C$ After the materials were dried out at 120t: in an electric oven, they were mixed with water, keeping the percentage of moisture content 25% and kneaded specimens which are hexahedron by $$ 250{\times}30{\times}8mm$$were produced and dried after calibrated at 200mm interval with a vernier caliper. After the materials were dried and glazed, they showed few shape-changes at $950^{\circ}C$ but began to changed at $1200^{\circ}C$,especially Bunchong and Ongki made rapid changes. In the case of color-change, White-Porcelain changed very little. The color of Blue-Porcelain, mixed A and B, Sanchong, Mullite changed to ]aune brilliant as temperature went up but Bunchong and Ongki changed to dark brown or dark chocolate under the same conditions. This study aims at suggestion of the basic data which minimize failure rates by recognizing the property of the materials on the basis of this study and regulating shape-change phenomena and sensitive changes of color when ceramic artists work.

• Science of Emotion and Sensibility
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• v.17 no.2
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• pp.123-134
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• 2014

Sensibilities to the clothing components such as style and color tone of fashion product are considered important to the consumers in fashion industry today. So the combinational study of clothing sensibility and proper end-use style are needed to improve the product refinements in developing process through scientific research method. The purpose of this study is to measure the sensibilities of the blouse type as a clothing component for it is a representative garment of women and to look for the best matching color tone according to blouse type. We surveyed the questionnaire to two hundred college students and found that there was a meaningful relational consistency between blouse type and color tone. Blouses have been told the best if they are of Bright color tone. They preferred Shirt blouse type and Bright color tone best of all. They are fond of Vivid color tone but they think Vivid tone is not so proper to the blouses. Each blouse has 1~2 best-fit color tones, and color sensibility affect the harmony of blouse style and color tone. The sensibilities of blouse type and color tone are deeply correlated each other regardless of subject's major or gender except a few cases.