• 한국농업기계학회:학술대회논문집
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• 한국농업기계학회 2006년도 하계 학술대회 논문집
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• pp.333-337
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• 2006

• Archives of Plastic Surgery
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• 제42권5호
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• pp.652-655
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• 2015

• 대한치과의사협회지
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• 제5권1호
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• pp.56-59
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• 1964

The authors have observed a case of giant-cell reparative granuloma which were occurred in the mandible of 30 year old man . 1.The lesion of accompanying inflammation was lacated at the anterior portion of the mandible. 2.Radiograph shows ovoid radiolucent shadow with irregular margin. 3. Microscopic section reveals granulation tissue and many multinucleated gaint cells exist adjacent to the hemorrhagic areas.

• Animal cells and systems
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• 제6권2호
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• pp.167-170
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• 2002

The long terminal repeats (LTRs) of human endogenous retrovirus (HERV) have been found to be coexpressed with sequences of closely located genes. It has been suggested that the LTR elements have contributed to the structural change or genetic variation of human genome connected to various diseases and evolution. We examined the HERV-W LTR elements in various cancer cells (2F7, A43l , A549, HepG2, MIA-PaCa-2, PC-3, RT4, SiHa, U-937, and UO-31). Using genomic DNA from the cancer cells, we performed PCR amplification and identified twelve new HERV-W LTR elements. Those LTR elements showed a high degree of sequence similarity (88-99％) with HERV-W LTR (AF072500). A phylogenetic tree obtained by the neighbor-joining method revealed that HERV-W LTR elements could be mainly divided into two groups through evolutionary divergence. Three HERV-W LTR elements (RT4-2, A43l-1, and UO3l-2) belonged to Group 1, whereas nine LTR elements (2F7-2, A549-1, A549-3, HepG2-3, MP2-2, PC3-1, SiHa-8, SiHa-10, and U937-1) belonged to Group 11. Taken together, our new sequence data of the HERV-W LTR elements may contribute to an understanding of tissue-specific cancer by genomic instability of LTR integration.

• 한국방사선학회논문지
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• 제12권3호
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• pp.427-433
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• 2018

비침습적 치료 효과에 대한 기대로 집속 초음파를 이용한 하지정맥류 치료에 대한 많은 연구가 진행되고 있다. 본 연구에서는 초음파 정맥류 정맥 치료 효과 평가에 적용할 수 있는 생체 조직 팬텀과 조직 등가 팬텀을 제시 하였다. 제작된 팬텀은 음향학적 특징과 초음파 조사에 따른 수축률을 평가함으로써 유용성을 평가하였다. 하지정맥류가 발생하는 조직의 구조를 고려하여 피부, 지방, 근육의 세 층으로 된 다층 구조 팬텀을 제작하였으며, 각 층을 구성하는 물질은 인체와 유사한 특성을 갖도록 제작하였다. 또한 혈관 유사물질을 매식한 다층 구조 팬텀과 동물 혈관을 이용한 다층 구조 팬텀, 동물 조직을 이용한 다층 구조 팬텀을 제작하였으며, 초음파 조사에 따른 혈관 유사 물질 및 혈관 조직의 수축 정도를 B-mode 영상을 이용하여 평가하였다. 본 연구의 결과를 통하여 제시된 팬텀이 초음파 하지정맥류 치료 평가에 유효하게 활용될 수 있을 것으로 판단되었다. 또한, 집속 초음파를 이용한 하지정맥류 치료 장비 개발 및 치료 효과 검증에 중요한 역할을 할 것으로 판단된다.

• Investigative Magnetic Resonance Imaging
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• 제19권3호
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• pp.153-161
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• 2015

Purpose: To identify the differential MRI findings between myxoid tumors and benign peripheral nerve sheath tumors (BPNSTs) in the musculoskeletal system. Materials and Methods: The study participants included a total of 35 consecutive patients who underwent MRI between September 2011 and December 2013. The patients were pathologically diagnosed with myxoid tumors (22 patients) or BPNSTs (13 patients). Evaluation was done by two radiologists, based on the following characteristics: size, margin, degree of signal intensity (SI) on T2-weighted images (T2WI), homogeneity of SI on T2WI, enhancement pattern, enhancement homogeneity, presence of cystic portion, internal fat component, presence of fat split sign, presence of target sign, presence of continuation with adjacent neurovascular bundle, and presence of surrounding halo. Results: Large size, high SI on T2WI, heterogeneous enhancement, and internal fat component were commonly observed in myxoid tumors, while homogenous enhancement, fat split sign, target sign were common in BPNSTs. The differences were statistically significant (P < 0.05). Other findings, such as margin, homogeneity of SI on T2WI, enhancement pattern (peripheral or solid), internal cystic portion, continuation with neurovascular bundle, and surrounding halo, did not show significant difference between myxoid tumors and BPNSTs (P > 0.05). Conclusion: In the differential diagnosis of myxoid tumors and BPNSTs involving the musculoskeletal system, several MRI findings such as degree of SI on T2WI, enhancement homogeneity, internal fat component, fat split sign, and target sign, may be helpful in establishing the diagnosis.

• 한국초지조사료학회지
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• 제41권3호
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• pp.162-167
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• 2021

Aluminum (Al) stress in acidic pH is known to decrease the growth and productivity of alfalfa. However, not much is known about how the application of silicon (Si) affects the Al stress response in alfalfa. This study was conducted to evaluate the effect of exogenous application of Si on the growth of alfalfa seedlings exposed to Al stress in pots. Alfalfa seedlings grown in pots for 2 weeks were treated either Al stress (pH 4.0, 0.2 mM Al) or Al stress + Si (1 mM) for 5 days, lengths and biomass of shoot and root, and chlorophyll and carotenoid contents in leaf tissues were analyzed respectively. Al stress treatment inhibited shoot and root growth, and decreased fresh and dry weights, and chlorophyll content in leaves, but increased carotenoid content. In contrast, when alfalfa seedlings treated with Al stress combined with Si, delayed growth caused by Al stress of shoot and root of alfalfa seedlings was restored, dry weight was increased and chlorophyll content of leaf tissue was increased, but carotenoid content was decreased. These results suggest that Si has a function of alleviating Al toxicity in alfalfa, of which it exhibits a mitigating effect by a function that overlaps with some of the intracellular functions of carotenoids.

• Archives of Plastic Surgery
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• 제43권6호
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• pp.551-558
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• 2016

Background Fascial free flaps have been widely used for reconstruction of the hand because they are thin. However, studies reporting objective data regarding the advantages of this approach are lacking. Thus, we report our experience with such flaps. Methods Forty-five cases of fascial free flaps between November 2006 and March 2014 were reviewed. Nine cases involving reconstructed dorsal or lateral defects were included. Four anterolateral thigh fascial free flaps and 5 lateral arm fascial free flaps were examined. Maximal flap contour was assessed by measuring reconstructed tissue thickness at the central area from the surface of the skin to below the bone in a vertical manner using ultrasonography and X-ray data. Contralateral regions were examined in the same manner and a comparative analysis was performed. A questionnaire survey regarding aesthetic satisfaction was also administered. Results All reconstructed parts had a thicker contour than the contralateral side. The average relative percentage of reconstructed tissue thickness was found to be 152% using ultrasonography and 143% using X-ray imaging. According to the aesthetic satisfaction survey, the average rate of satisfaction for patients was 62%, and satisfaction with the flap contour was 72%. Conclusions Using a fascial free flap, the reconstructed tissue was approximately $1.5{\times}$ as thick as the contour of the normal side, which led to positive responses regarding aesthetic satisfaction.

• Archives of Plastic Surgery
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• 제47권5호
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• pp.451-459
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• 2020

Background For volar soft tissue defects of the proximal interphalangeal (PIP) joint, free flaps are technically challenging, but have more esthetic and functional advantages than local or distant flaps. In this study, we compared the long-term surgical outcomes of arterial (hypothenar, thenar, or second toe plantar) and venous free flaps for volar defects of the PIP joint. Methods This was a single-center retrospective review of free flap coverage of volar defects between the distal interphalangeal and metacarpophalangeal joint from July 2010 to August 2019. Patients with severe crush injuries (degloving, tendon or bone defects, or comminuted/intra-articular fractures), thumb injuries, multiple-joint and finger injuries, dorsal soft tissue defects, and defects >6 cm in length were excluded from the study, as were those lost to follow-up within 6 months. Thirteen patients received arterial (hypothenar, thenar, or second toe plantar) free flaps and 12 received venous free flaps. Patients' age, follow-up period, PIP joint active range of motion (ROM), extension lag, grip-strength ratio of the injured to the uninjured hand, and Quick Disabilities of Arm, Shoulder & Hand (QuickDASH) score were compared between the groups. Results Arterial free flaps showed significantly higher PIP joint active ROM (P=0.043) and lower extension lag (P =0.035) than venous free flaps. The differences in flexion, grip strength, and QuickDASH scores were not statistically significant. Conclusions The surgical outcomes of arterial free flaps were superior to those of venous free flaps for volar defects of the PIP joint.

• Journal of Acupuncture Research
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• 제24권4호
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• pp.125-142
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• 2007

calculus pharmacopuncture. Porcine skin including fat tissue after treated Fel ursi and Bovis calculus pharmacopuncture by means of the dosage dependent variation are investigated the histologic changes after injection of these pharmacopuncture. Results: Following results were obtained from the preadipocyte proliferation and lipolysis of adipocyte and histologic investigation of fat tissue. 1. Fel ursi and Bovis calculus pharmacopuncture showed the effect of decreased preadipocyte proliferation on the high dosage($1mg/m{\ell}$). 2. Fel ursi pharmacopuncture showed the effect of decreased the activity of glycerol-3-phosphate dehydrogenase (GPDH) on the high dosage($1mg/m{\ell}$) and Bovis calculus pharmacopuncture significantly showed from $0.1mg/m{\ell}$ concentration. 3. Fel ursi pharmacopuncture was not showed the effect of lipolysis, but Bovis calculus pharmacopuncture was increased the effect of lipolysis in all concentration significantly. 4. Investigated the histological changes in porcine fat tissue after treated Fel ursi and Bovis calculus pharmacopuncture, we knew that these pharmacopuncture was showed significant activity to the lysis of cell membranes in all concentration. Conclusion : These results suggest that Fel ursi and Bovis calculus pharmacopuncture efficiently induces diminish proliferation of preadipocyte and lipolysis in adipose tissue.