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'OFF' Response and Its Characteristics of Guinea Pig Ureter (기니픽 요관(尿管)에 있어서 OFF Response 발생과 그 특징)

  • Hong, K.W.;Rhim, B.Y.;Peter Binancani;Weiss Robert M.
    • The Korean Journal of Pharmacology
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    • v.16 no.1 s.26
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    • pp.25-34
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    • 1980
  • The in vitro guinea pig ureter responded to 5 sec trains of electrical stimuli with two contractions; the first an 'on response' (ON) occurred with $0.1{\sim}0.3$ sec after the onset o the stimulus train, the second an 'off response'(OFF) occurred $0.2{\sim}1.0$ sec after the termination of the stimulus train. Relaxation occurred between the two responses during a time when the stimulus was still being delivered. Longer duration and/or higher frequencies of stimuli within the train were required to elicit the OFF than the ON. Decreasing temperature from $37^{\circ}$ to $22^{\circ}$ decreased ON amplitude and increased OFF amplitude. $Ca^{++}$-free solution, 2 mM EDTA, 1 mM $Mn^{++}$ or $1{\mu}M$ verapamil rapidly abolished ON. OFF persisted when ON had disappeared by repeated stimulation at 0.12 train per sec. Conversely, caffeine, $50{\mu}M$ and theophylline, $10{\mu}M$ abolished OFF with only slight reduction of ON, and sodium nitroprusside decreased preferentially ON amplitude rather than OFF. Relaxation between ON and OFF was incomplete in low $Na^+$ solution. ON and OFF were not affected by the neural blockers tetrodotoxin, atropine or phentolamine, also pyrilamine and methysergide, and relaxation between ON and OFF was $Na^+$ dependent. Furthermore, ON depends on free $Ca^{++}$ and OFF is more dependent on bound or stored $Ca^{++}$.

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Changes of ecological niche in Quercus serrata and Quercus aliena under climate change (갈참나무와 졸참나무의 기후변화에 따른 생태지위 변화)

  • Yoon-Seo Kim;Jae-Hoon Park;Eui-Joo Kim;Jung-Min Lee;Ji-Won Park;Yeo-Bin Park;Se-Hee Kim;Ji-Hyun Seo;Bo-Yeon Jeon;Hae-In Yu;Gyu-Ri Kim;Ju-Seon Lee;Yeon-Jun Kang;Young-Han You
    • Journal of Wetlands Research
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    • v.25 no.3
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    • pp.205-212
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    • 2023
  • This study was attempted to find out how the ecological niche and interspecies relationship of Quercus aliena and Q. serrata, which are the main constituents of potential natural vegetation along the riverside of mountains in Korea, under climate change conditions. To this end, soil moisture and soil nutrients were treated with 4 grad ients under climate change conditions with elevated CO2 and temperature, plants we re harvested at the end of the growing season, growth responses of traits were measured, ecological niche breadth and overlap were calculated, and it was compared with that of the control group(ambient condition). In addition, the relationship between the two species was analyzed by principal component analysis using trait values. As a result, the ecological niche breadth of Q. aliena was wider than that of Q. serrata under the moisture environment conditions under climate change. Under nutrient conditions, the ecological niche of the two species were similar. In addition, the ecological overlap for soil moisture of Q. aliena and Q. serrata was wider than the soil nutrient gradient under climate change. The species with traits in which the increase in ecological niche breadth due to climate change occurred more than the decrease was Q. aliena in both water and nutrient gradients. And in the responses of the population level, due to climate change, the adaptability of Q. aliena was higher than that of Q. serrata under the soil moisture condition, but the two species were similar under the nutrient condition. These results mean that the competition between the two species occurs more severely in the water environment under climate change conditions, and at that time, Q. aliena has higher adaptability than Q. serrata.

An Installation and Model Assessment of the UM, U.K. Earth System Model, in a Linux Cluster (U.K. 지구시스템모델 UM의 리눅스 클러스터 설치와 성능 평가)

  • Daeok Youn;Hyunggyu Song;Sungsu Park
    • Journal of the Korean earth science society
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    • v.43 no.6
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    • pp.691-711
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    • 2022
  • The state-of-the-art Earth system model as a virtual Earth is required for studies of current and future climate change or climate crises. This complex numerical model can account for almost all human activities and natural phenomena affecting the atmosphere of Earth. The Unified Model (UM) from the United Kingdom Meteorological Office (UK Met Office) is among the best Earth system models as a scientific tool for studying the atmosphere. However, owing to the expansive numerical integration cost and substantial output size required to maintain the UM, individual research groups have had to rely only on supercomputers. The limitations of computer resources, especially the computer environment being blocked from outside network connections, reduce the efficiency and effectiveness of conducting research using the model, as well as improving the component codes. Therefore, this study has presented detailed guidance for installing a new version of the UM on high-performance parallel computers (Linux clusters) owned by individual researchers, which would help researchers to easily work with the UM. The numerical integration performance of the UM on Linux clusters was also evaluated for two different model resolutions, namely N96L85 (1.875° ×1.25° with 85 vertical levels up to 85 km) and N48L70 (3.75° ×2.5° with 70 vertical levels up to 80 km). The one-month integration times using 256 cores for the AMIP and CMIP simulations of N96L85 resolution were 169 and 205 min, respectively. The one-month integration time for an N48L70 AMIP run using 252 cores was 33 min. Simulated results on 2-m surface temperature and precipitation intensity were compared with ERA5 re-analysis data. The spatial distributions of the simulated results were qualitatively compared to those of ERA5 in terms of spatial distribution, despite the quantitative differences caused by different resolutions and atmosphere-ocean coupling. In conclusion, this study has confirmed that UM can be successfully installed and used in high-performance Linux clusters.

A Method of Reproducing the CCT of Natural Light using the Minimum Spectral Power Distribution for each Light Source of LED Lighting (LED 조명의 광원별 최소 분광분포를 사용하여 자연광 색온도를 재현하는 방법)

  • Yang-Soo Kim;Seung-Taek Oh;Jae-Hyun Lim
    • Journal of Internet Computing and Services
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    • v.24 no.2
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    • pp.19-26
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    • 2023
  • Humans have adapted and evolved to natural light. However, as humans stay in indoor longer in modern times, the problem of biorhythm disturbance has been induced. To solve this problem, research is being conducted on lighting that reproduces the correlated color temperature(CCT) of natural light that varies from sunrise to sunset. In order to reproduce the CCT of natural light, multiple LED light sources with different CCTs are used to produce lighting, and then a control index DB is constructed by measuring and collecting the light characteristics of the combination of input currents for each light source in hundreds to thousands of steps, and then using it to control the lighting through the light characteristic matching method. The problem with this control method is that the more detailed the steps of the combination of input currents, the more time and economic costs are incurred. In this paper, an LED lighting control method that applies interpolation and combination calculation based on the minimum spectral power distribution information for each light source is proposed to reproduce the CCT of natural light. First, five minimum SPD information for each channel was measured and collected for the LED lighting, which consisted of light source channels with different CCTs and implemented input current control function of a 256-steps for each channel. Interpolation calculation was performed to generate SPD of 256 steps for each channel for the minimum SPD information, and SPD for all control combinations of LED lighting was generated through combination calculation of SPD for each channel. Illuminance and CCT were calculated through the generated SPD, a control index DB was constructed, and the CCT of natural light was reproduced through a matching technique. In the performance evaluation, the CCT for natural light was provided within the range of an average error rate of 0.18% while meeting the recommended indoor illumination standard.

Ecological health assessment of Yangjaecheon and Yeouicheon using biotic index and water quality (생물지수와 수질을 이용한 양재천과 여의천의 생태건강성평가)

  • Jin Hyo Lee;Hyeon Han;Jun Yeon Lee;Young Seop Cha;Seog Ju Cho
    • Korean Journal of Environmental Biology
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    • v.40 no.2
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    • pp.172-186
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    • 2022
  • Benthic macroinvertebrates are important ecological and environmental indicators as primary or secondary consumers, and therefore are widely used in the evaluation of aquatic environments. However, there are no comprehensive river ecosystem monitoring surveys that link the major physicochemical water quality items with benthic macroinvertebrates in urban streams. Therefore, this study investigated the distribution characteristics of benthic macroinvertebrates and physicochemical water quality items (17 items) in Yangjaecheon and Yeouicheon from 2019 to 2020. At the same time, by applying Spearman's rank correlation analysis and nonmetric multidimensional scaling (nMDS) analysis in the water quality data and biotic index, we tried to provide basic data for diagnosing the current status of river ecosystems in major urban rivers in Seoul. Based on the study results, a total of 39 species and 3,787 individuals were identified in Yangjaecheon, the water quality(based on BOD, TOC, and TP) of Yangjaecheon was higher than Grade Ib(good), and the BMI using benthic macroinvertebrates appeared as Grade C(normal) at all the sites. In Yeouicheon, a total of 51 species and 4,199 individuals were identified, the water quality(based on BOD, TOC, TP) was higher than Grade Ib(good) similar to Yangjaecheon, and the BMI of both Upstream and Saewon bridge was Grade B(good), while Yeoui bridge was Grade C(normal). Overall, analysis results for the distribution of benthic macroinvertebrates by a nonmetric multidimensional scaling method showed no significant difference between the two streams (p=0.1491). Also, significant environmental variables related to benthic macroinvertebrates distribution were determined as water temperature and DO. On the other hand, the results of the correlation analysis between biotic index and major water quality items confirmed that R1 and BMI could be used for on-site urban river water quality evaluation.

A Comprehensive Review of Geological CO2 Sequestration in Basalt Formations (현무암 CO2 지중저장 해외 연구 사례 조사 및 타당성 분석)

  • Hyunjeong Jeon;Hyung Chul Shin;Tae Kwon Yun;Weon Shik Han;Jaehoon Jeong;Jaehwii Gwag
    • Economic and Environmental Geology
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    • v.56 no.3
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    • pp.311-330
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    • 2023
  • Development of Carbon Capture and Storage (CCS) technique is becoming increasingly important as a method to mitigate the strengthening effects of global warming, generated from the unprecedented increase in released anthropogenic CO2. In the recent years, the characteristics of basaltic rocks (i.e., large volume, high reactivity and surplus of cation components) have been recognized to be potentially favorable in facilitation of CCS; based on this, research on utilization of basaltic formations for underground CO2 storage is currently ongoing in various fields. This study investigated the feasibility of underground storage of CO2 in basalt, based on the examination of the CO2 storage mechanisms in subsurface, assessment of basalt characteristics, and review of the global research on basaltic CO2 storage. The global research examined were classified into experimental/modeling/field demonstration, based on the methods utilized. Experimental conditions used in research demonstrated temperatures ranging from 20 to 250 ℃, pressure ranging from 0.1 to 30 MPa, and the rock-fluid reaction time ranging from several hours to four years. Modeling research on basalt involved construction of models similar to the potential storage sites, with examination of changes in fluid dynamics and geochemical factors before and after CO2-fluid injection. The investigation demonstrated that basalt has large potential for CO2 storage, along with capacity for rapid mineralization reactions; these factors lessens the environmental constraints (i.e., temperature, pressure, and geological structures) generally required for CO2 storage. The success of major field demonstration projects, the CarbFix project and the Wallula project, indicate that basalt is promising geological formation to facilitate CCS. However, usage of basalt as storage formation requires additional conditions which must be carefully considered - mineralization mechanism can vary significantly depending on factors such as the basalt composition and injection zone properties: for instance, precipitation of carbonate and silicate minerals can reduce the injectivity into the formation. In addition, there is a risk of polluting the subsurface environment due to the combination of pressure increase and induced rock-CO2-fluid reactions upon injection. As dissolution of CO2 into fluids is required prior to injection, monitoring techniques different from conventional methods are needed. Hence, in order to facilitate efficient and stable underground storage of CO2 in basalt, it is necessary to select a suitable storage formation, accumulate various database of the field, and conduct systematic research utilizing experiments/modeling/field studies to develop comprehensive understanding of the potential storage site.

Phytoplankton Response to Short-term Environmental Changes in the Vicinity of a Fish Cage Farm of Tongyeong Obi in Summer (통영 오비도 어류양식장 주변에서 하계 수계 내 단주기 환경요인의 변화에 따른 미세조류 반응)

  • Lee, Minji;Baek, Seung Ho
    • Journal of Marine Life Science
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    • v.2 no.2
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    • pp.62-69
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    • 2017
  • In order to assess the potential environmental factors in the vicinity of a fish cage farm, we investigated the biotic and abiotic factors during a short-term period in summer 2016 in two inner stations of Tongyeong Obi. High water temperature on August 10th was apparent among the full depth of up to 29℃, which might have been related to the abnormally high temperatures of large amounts of the Changjiang River discharge along the Tongyeong coast. The concentration of nitrate+nitrite, ammonium, phosphate, and silicate ranged from 0.08 to 5.11 μM, 0.08 to 34.62 μM, 0.01 to 1.15 μM, and 1.46 to 31.79 μM, respectively. The nutrients were mainly supplied by precipitation and leaching from the bottom sediments in the fish culture farm area. It was not retained for a long duration because of the phytoplankton consumption and diffusion by water currents. The chlorophyll a concentration varied from 0.49 ㎍ l-1 to 7.39 ㎍ l-1. At that time, Chaetoceros debilis, C. pseudocurvisetus, and Pseudo-nitzschia delicatissima were rapidly proliferated and reached the level of 4.74 × 109 cells l-1. In particular, the lowest dissolved oxygen was recorded at 4.52 ㎍ l-1 at the bottom layer after bloom. Therefore, even though phytoplankton blooms in summer have frequently occurred in a fish culture farm area, the oxygen-deficient environments were not found in neither the surface nor bottom layers, which implied that the water masses might be well exchanged from the mouth of the northwest and southeast between Obi and Mireuk Island in the study area.

A Study on change in thermal properties and chemical structure of Zr-Ni delay system by aging (노화에 따른 Zr-Ni계 지연관의 열 특성 및 화학적 구조 변화에 관한 연구)

  • Park, Byung Chan;Chang, Il Ho;Kim, Sun Tae;Hwang, Taek Sung;Lee, Seungho
    • Analytical Science and Technology
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    • v.22 no.4
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    • pp.285-292
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    • 2009
  • It has been observed that, after long term storage, some ammunitions are misfired by tamping (combustionstopping) due to aging of the chemicals loaded in the ammunitions. Used in ammunitions are percussion powder which provides the initial energy, igniter which ignites the percussion powder, and a delay system that delays the combustion for a period of time. The percussion powder is loaded first, followed by the igniter and then the delay system, and the ammunitions explode by the energy being transferred in the same order. Tamping occurs by combustion-stopping of the igniter or insufficient energy transfer from the igniter to the delay system or the combustion-stopping of the delay system, which are suspected to be caused by low purity of the components, inappropriate mixing ratio, size distribution of particulate components, type of the binder, blending method, hydrolysis by the humidity penetrated during the long term storage, and chemical changes of the components by high temperature. Goal of this study is to find the causes of the combustion-stopping of the igniter and the delay system of the ammunitions after long term storage. In this study, a method was developed for testing of the combustion-stopping, and the size distributions of the particulate components were analyzed with field-flow fractionation (FFF), and then the mechanism of chemical change during long term storage was investigated by thermal analysis (differential scanning calorimetry), XRD (X-ray diffractometry), and XPS (X-ray photoelectron spectroscopy). For the ignition system, M (metal)-O (oxygen) and M-OH peaks were observed at the oxygen's 1s position in the XPS spectrum. It was also found by XRD that $Fe_3O_4$ was produced. Thus it can be concluded that the combustion-stopping is caused by reduction in energy due to oxidation of the igniter.

Evaluation of Water Quality Characteristics of Saemangeum Lake Using Statistical Analysis (통계분석을 이용한 새만금호의 수질특성 평가)

  • Jong Gu Kim
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.29 no.4
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    • pp.297-306
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    • 2023
  • Saemangeum Lake is the largest artificial lake in Korea. The continuous deterioration of lake water quality necessitates the introduction of novel water quality management strategies. Therefore, this study aims to identify the spatiotemporal water quality characteristics of Saemangeum Lake using data from the National Water Quality Measurement Network and provide basic information for water quality management. In the water quality parameters of Saemangeum Lake, water temperature and total phosphorous content were correlated, and salt, total nitrogen content, pH, and chemical oxygen demand were significantly correlated. Other parameters showed a low correlation. The spatial principal component analysis of Saemangeum Lake showed the characteristics of its four zones. The mid-to-downstream section of the river affected by freshwater inflow showed a high nutrient salt concentration, and the deep-water section of the drainage gate and the lake affected by seawater showed a high salt concentration. Two types of water qualities were observed in the intermediate water area where river water and outer sea water were mixed: waters with relatively low salt and high chemical oxygen demand, and waters with relatively low salt and high pH concentration. In the principal component analysis by time, the water quality was divided into four groups based on the observation month. Group I occurred during May and June in late spring and early summer, Group II was in early spring (March-April) and late autumn (November-December), Group III was in winter (January-February), and Group IV was in summer (July-October) during high temperatures. The water quality characteristics of Saemangeum Lake were found to be affected by the inflow of the upper Mangyeong and Dongjin rivers, and the seawater through the Garuk and Shinshi gates installed in the Saemangeum Embankment. In order to achieve the target water quality of Saemangeum Lake, it is necessary to establish water quality management measures for Saemangeum Lake along with pollution source management measures in the upper basin.

Spring Shoot Damage and Cold Hardiness of Grape in Different Varieties and Phenological Stages (봄철 포도 신초 저온 피해 양상과 품종별 전엽기 내한성 비교)

  • Dongyong Lee;Suhyun Ryu;Jae Hoon Jeong;Jeom Hwa Han;Jung-Gun Cho;Seul-Ki Lee;Sihyeong Jang
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.25 no.4
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    • pp.359-367
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    • 2023
  • Grapes are one of the most important fruit trees both domestically and globally. Recently, changes in plant phenology and frequent low temperatures due to climate change are increasing the possibility of damage to grape shoots in spring, which is a serious threat to grape production. This study was conducted to investigated the severity of shoots damage and the change of free sugar content in the plant organs by phenological stage, especially, from germination to leafing period. Furthermore, in order to compare the cold hardiness among grape varieties including 'Campbell Early', 'Kyoho' and 'Shine Muscat' widely grown in Korea, lethal temperature (LT50) and free sugar content by grape variety were analyzed. Shoot damage by low temperatures continued to increase as the phenological stage progressed gradually, from the bud burst to the fourth leafing stage. On the other hand, the free sugar content of each organ except leaves continued to decrease, showing pattern to similar to cold hardiness. This indicates a close relationship between free sugar content and cold hardiness. In terms of cold hardiness comparison among grape varieties, 'Shine Muscat' showed the highest cold resistance in the leafing stage with the lowest LT50 and the highest total free sugar content. Next was 'Kyoho' and 'Campbell Early'. There are clear differences in cold hardiness depending on the variety. However, it is not the same at all growth stage. It may change according to phenological stage and influenced by free sugar content at that time.